Novel full length cDNA

ABSTRACT

Novel full-length cDNAs are provided. 1970 cDNA derived from human have been isolated. The full-length nucleotide sequences of the cDNA and amino acid sequences encoded by the nucleotide sequences have been determined. Because the cDNA of the present invention are full-length and contain the translation start site, they provide information useful for analyzing the functions of the polypeptide.

FIELD OF THE INVENTION

The present invention relates to polynucleotides encoding novelpolypeptides, polypeptides encoded by the polynucleotides, and new usesof these.

BACKGROUND OF THE INVENTION

Currently, the sequencing projects, the determination and analysis ofthe genomic DNA of various living organisms have been in progress allover the world. The whole genomic sequences of more than 40 species ofprokaryotes, a lower eukaryote, yeast, a multicellular eukaryote, C.elegans, and a higher plants, arabidopsis, etc. are already determined.For human genome, presumably having 3 billion base pairs, the analysiswas advanced under global cooperative organization, and a draft sequencewas disclosed in 2001. Moreover, all the structures are to be clear andto be disclosed in 2002-2003. The aim of the determination of genomicsequence is to reveal the functions of all genes and their regulationand to understand living organisms as a network of interactions betweengenes, proteins, cells or individuals through deducing the informationin a genome, which is a blueprint of the highly complicated livingorganisms. To understand living organisms by utilizing the genomicinformation from various species is not only important as an academicsubject, but also socially significant from the viewpoint of industrialapplication.

However, determination of genomic sequences itself cannot identify thefunctions of all genes. For example, as for yeast, only the function ofapproximately half of the 6000 genes, which is predicted based on thegenomic sequence, was able to be deduced. On the other hand, the humangenome has been estimated to contain about 30,000-40,000 genes. Further,100,000 or more types of mRNAs are said to exist when variants producedby alternative splicing are taken into consideration. Therefore, it isdesirable to establish “a high throughput analysis system of the genefunctions” which allows us to identify rapidly and efficiently thefunctions of vast amounts of the genes obtained by the genomicsequencing.

Many genes in the eukaryotic genome are split by introns into multipleexons. Thus, it is difficult to predict correctly the structure ofencoded protein solely based on genomic information. In contrast, cDNA,which is produced from mRNA that lacks introns, encodes a protein as asingle continuous amino acid sequence and allows us to identify theprimary structure of the protein easily. In human cDNA research, todate, more than three million ESTs (Expression Sequence Tags) arepublicly available, and the ESTs presumably cover not less than 80% ofall human genes.

The information of ESTs is utilized for analyzing the structure of humangenome, or for predicting the exon-regions of genomic sequences or theirexpression profile. However, many human ESTs have been derived fromproximal regions to the 3′-end of cDNA, and information around the5′-end of mRNA is extremely little. Among human cDNAs, the number of thecorresponding mRNAs whose encoding full-length protein sequences arededuced is approximately 13,000.

It is possible to identify the transcription start site of mRNA on thegenomic sequence based on the 5′-end sequence of a full-length cDNA, andto analyze factors involved in the stability of mRNA that is containedin the cDNA, or in its regulation of expression at the translationstage. Also, since a full-length cDNA contains atg codon, thetranslation start site, in the 5′-region, it can be translated into aprotein in a correct frame. Therefore, it is possible to produce a largeamount of the protein encoded by the cDNA or to analyze biologicalactivity of the expressed protein by utilizing an appropriate expressionsystem. Thus, analysis of a full-length cDNA provides valuableinformation which complements the information from genome sequencing.Also, full-length cDNA clones that can be expressed are extremelyvaluable in empirical analysis of gene function and in industrialapplication.

Therefore, if a novel human full-length cDNA is isolated, it can be usedfor developing medicines for diseases in which the gene is involved. Theprotein encoded by the gene can be used as a drug by itself. Thus, ithas great significance to obtain a full-length cDNA encoding a novelhuman protein.

In particular, human secretory proteins or membrane proteins would beuseful by itself as a medicine like tissue plasminogen activator (TPA),or as a target of medicines like membrane receptors. In addition, genesfor signal transduction-related proteins (protein kinases, etc.),glycoprotein-related proteins, transcription-related proteins, etc. aregenes whose relationships to human diseases have been elucidated.Moreover, genes for disease-related proteins form a gene group rich ingenes whose relationships to human diseases have been elucidated.

Therefore, it has great significance to isolate novel full-length cDNAclones of human, only few of which has been isolated. Especially,isolation of a novel cDNA clone encoding a secretory protein or membraneprotein is desired since the protein itself would be useful as amedicine, and also the clones potentially include a gene involved indiseases. In addition, genes encoding proteins that are involved insignal transduction, glycoprotein, transcription, or diseases areexpected to be useful as target molecules for therapy, or as medicinesthemselves. These genes form a gene group predicted to be stronglyinvolved in diseases. Thus, identification of the full-length cDNAclones encoding those proteins has great significance.

SUMMARY OF THE INVENTION

An objective of the present invention is to provide polynucleotidesencoding novel polypeptides, polypeptides encoded by thepolynucleotides, and novel usages of these.

The inventors have developed a method for efficiently cloning, from acDNA library having very high fullness-ratio, a human full-length cDNAthat is predicted to be a full-length cDNA clone, where the cDNA libraryis synthesized by an improved method (WO 01/04286) of the oligo-cappingmethod (K. Maruyama and S. Sugano, Gene, 138: 171-174 (1994); Y. Suzukiet al., Gene, 200: 149-156 (1997)). Then, the nucleotide sequences ofcDNA clones whose fullness ratio is high, obtained by this method, weredetermined mainly from their 5′-ends, and, if required, from 3′-ends.

Further, representative clones, which were estimated to be novel andfull-length, among the clones obtained, were analyzed for theirfull-length nucleotide sequences. The determined full-length nucleotidesequences were analyzed by BLAST homology search of the databases shownbelow. Because the homology search of the present invention is carriedout based on the information of full-length cDNAs including the entirecoding regions, homology to every part of a polypeptide can be analyzed.Thus, in the present invention, the reliability of homology search hasbeen greatly improved.

-   [1] Swissprot    (http://www.ebi.ac.uk/ebi_docsSwissProt_db/swisshome.html),-   [2] GenBank (http://www.ncbi.nlm.nih.gov/web/GenBank),-   [3] UniGene (Human) (http://www.ncbi.nlm.nih.gov/UniGene), and-   [4] nr (a protein database, which has been constructed by combining    data of coding sequences (CDS) in nucleotide sequences deposited in    GenBank, and data of SwissProt, PDB    (http://www.rcsb.org/pdb/index.html), PIR    (http://pir.georgetown.edu/pirwww/pirhome.shtml), and PRF    (http://www.prf.or.jp/en/); overlapping sequences have been    removed.)

Further, the gene expression profiles of cDNA clones whose full-lengthnucleotide sequence had been determined were studied by analyzing thelarge-scale cDNA database constructed based on the 5′-end nucleotidesequences of cDNAs obtained. In addition to the analysis for theexpression profile by computer, the profiles of gene expression inliving cells were also determined by PCR. The present inventors revealedthe usefulness of the genes of the present invention based on theseanalysis results.

In the present invention, gene functions were revealed by the analysisof expression profiles in silico based on the information of full-lengthnucleotide sequences. The expression profiles used in the expressionfrequency analysis were studied based on the database containingsufficient amount of fragment sequence data. The expression frequencyanalysis was carried out by referring, for these expression profiles, tothe full-length nucleotide sequences of many cDNA clones obtained in thepresent invention. Thus, a highly reliable analysis can be achieved byreferring to the full-length nucleotide sequences of a wide variety ofgenes for the sufficiently large population for analysis (expressionprofiles). Namely, the results of expression frequency analysis usingthe full-length sequences of the present invention more preciselyreflect the gene expression frequency in tissues and cells from which acertain cDNA library was derived. In other words, the information offull-length cDNA nucleotide sequence of the present invention made itpossible to achieve the highly reliable expression frequency analysis.

The full-length cDNA clones of this invention were obtained by themethod comprising the steps of [1] preparing libraries containing cDNAswith the high fullness ratio by oligo-capping, and [2] assembling 5′-endsequences and selecting one with the highest probability of completenessin length in the cluster formed (there are many clones longer in the5′-end direction). However, the uses of primers designed based on the5′- and 3′-end sequences of polynucleotides provided by the presentinvention enable readily obtaining full-length cDNAs without such aspecial technique. The primer, which is designed to be used forobtaining cDNAs capable of being expressed, is not limited to the 5′-and 3′-end sequences of polynucleotide.

Specifically, the present invention relates to a polynucleotide selectedfrom the group consisting of the following (a) to (g):

-   -   (a) a polynucleotide comprising a protein-coding region of the        nucleotide sequence of any one of SEQ ID NOs shown in Table 1;    -   (b) a polynucleotide encoding a polypeptide comprising the amino        acid sequence of any one of SEQ ID NOs shown in Table 1;    -   (c) a polynucleotide comprising a nucleotide sequence encoding a        polypeptide comprising the amino acid sequence of any one of SEQ        ID NOs shown in Table 1, wherein, in said amino acid sequence,        one or more amino acids have been substituted, deleted,        inserted, and/or added, and wherein said nucleotide sequence        encodes a polypeptide functionally equivalent to a polypeptide        comprising the selected amino acid sequence;    -   (d) a polynucleotide hybridizing under stringent conditions to a        polynucleotide comprising the nucleotide sequence of any one of        SEQ ID NOs shown in Table 1, wherein said nucleotide sequence        encodes a polypeptide functionally equivalent to a polypeptide        encoded by the selected nucleotide sequence;    -   (e) a polynucleotide comprising a nucleotide sequence encoding a        partial amino acid sequence of a polypeptide encoded by the        polynucleotide according to any one of (a) to (d);    -   (f) a polynucleotide comprising a nucleotide sequence having at        least 70% identity to the nucleotide sequence of (a); and    -   (g) a polynucleotide comprising a nucleotide sequence having at        least 90% identity to the nucleotide sequence of (a).

The present invention also relates to a polypeptide encoded by theabove-mentioned polynucleotide or a partial peptide thereof, an antibodybinding to the polypeptide or the peptide, and a method forimmunologically assaying the polypeptide or the peptide, which comprisesthe steps of contacting the polypeptide or the peptide with theantibody, and observing the binding between the two.

Furthermore, the present invention features a vector comprising theabove-mentioned polynucleotide, a transformant carrying thepolynucleotide or the vector, a transformant carrying the polynucleotideor the vector in an expressible manner, and a method for producing thepolypeptide or the peptide, which comprises the steps of culturing thetransformant and recovering an expression product.

Another feature of the present invention is an oligonucleotidecomprising at least 15 nucleotides, said oligonucleotide comprising anucleotide sequence complementary to the nucleotide sequence of any oneof SEQ ID NOs: 1 to 1970 or to a complementary strand thereof. Thisoligonucleotide can be used as a primer for synthesizing theabove-mentioned polynucleotide or used as a probe for detecting thepolynucleotide. The present invention includes an antisensepolynucleotide against the polynucleotide or a part thereof, and amethod for detecting the polynucleotide, which comprises the followingsteps of:

-   a) incubating a target polynucleotide with the oligonucleotide under    hybridizable conditions, and-   b) detecting hybridization of the target polynucleotide with the    oligonucleotide.

Still another feature of the present invention is a database ofpolynucleotides and/or polypeptides, said database comprisinginformation on at least one of the nucleotide sequences of SEQ ID NOs: 1to 1970 and/or on at least one of the amino acid sequences of SEQ IDNOs: 1971 to 3940.

Herein, “polynucleotide” is defined as a molecule, such as DNA and RNA,in which multiple nucleotides are polymerized. There are no limitationson the number of the polymerized nucleotides. In case that the polymercontains relatively low number of nucleotides, it is also described asan “oligonucleotide”, which is included in the “polynucleotide” of thepresent invention. The polynucleotide or the oligonucleotide of thepresent invention can be a natural or chemically synthesized product.Alternatively, it can be synthesized using a template polynucleotide byan enzymatic reaction such as PCR. Furthermore, the polynucleotide ofthe present invention may be modified chemically. Moreover, not only asingle-strand polynucleotide but also a double-strand polynucleotide isincluded in the present invention. In this specification, especially inclaims, when the polynucleotide is described merely as “polynucleotide”,it means not only a single-strand polynucleotide but also adouble-strand polynucleotide. When it means double-strandpolynucleotide, the nucleotide sequence of only one chain is indicated.However, based on the nucleotide sequence of a sense chain, thenucleotide sequence of the complementary strand thereof is essentiallydetermined.

As used herein, an “isolated polynucleotide” is a polynucleotide thestructure of which is not identical to that of any naturally occurringpolynucleotide or to that of any fragment of a naturally occurringgenomic polynucleotide spanning more than three separate genes. The termtherefore includes, for example, (a) a DNA which has the sequence ofpart of a naturally occurring genomic DNA molecule in the genome of theorganism in which it naturally occurs; (b) a polynucleotide incorporatedinto a vector or into the genomic DNA of a prokaryote or eukaryote in amanner such that the resulting molecule is not identical to anynaturally occurring vector or genomic DNA; (c) a separate molecule suchas a cDNA, a genomic fragment, a fragment produced by polymerase chainreaction (PCR) or a restriction fragment; and (d) a recombinantnucleotide sequence that is part of a hybrid gene, i.e., a gene encodinga fusion polypeptide. Specifically excluded from this definition arepolynucleotides of DNA molecules present in mixtures of different (i)DNA molecules, (ii) transfected cells, or (iii) cell clones; e.g., asthese occur in a DNA library such as a cDNA or genomic DNA library.

The term “substantially pure” as used herein in reference to a givenprotein or polypeptide means that the protein or polypeptide issubstantially free from other biological macromolecules. For example,the substantially pure protein or polypeptide is at least 75%, 80%, 85%,95%, or 99% pure by dry weight. Purity can be measured by anyappropriate standard method known in the art, for example, by columnchromatography, polyacrylamide gel electrophoresis, or HPLC analysis.

All the cDNAs provided by the present invention are full-length cDNAs.The “full-length cDNA” herein means that the cDNA contains the ATGcodon, which is the start point of translation therein. The untranslatedregions upstream and downstream of the protein-coding region, both ofwhich are naturally contained in natural mRNAs, are not indispensable.It is preferable that the full-length cDNAs of the present inventioncontain the stop codon.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1 shows the restriction map of the vector pME18SFL3.

DETAILED DESCRIPTION OF THE INVENTION

All the clones (1970 clones) of the present invention are novel andencode the full-length polypeptides. Further, all the clones are cDNAswith the high fullness ratio, which were obtained by oligo-cappingmethod, and also clones which are not identical to any of known humanmRNAs (namely, novel clones) selected by searching, for the 5′-endsequences, mRNA sequences with the annotation of “complete cds” in theGenBank and UniGene databases by using the BLAST homology search [S. F.Altschul, W. Gish, W. Miller, E. W. Myers & D. J. Lipman, J. Mol. Biol.,215: 403-410 (1990); W. Gish & D. J. States, Nature Genet., 3: 266-272(1993)]; they are also clones that were assumed to have higher fullnessratio among the members in the cluster formed by assembling. Most of theclones assessed to have high fullness ratio in the cluster had thenucleotide sequences longer in the 5′-end direction.

All the full-length cDNAs of the present invention can be synthesized bya method such as PCR (Current protocols in Molecular Biology edit.Ausubel et al. (1987) Publish. John Wiley & Sons Section 6.1-6.4) usingprimer sets designed based on the 5′-end and 3′-end sequences or usingprimer sets of primers designed based on the 5′-end sequences and aprimer of oligo dT sequence corresponding to poly A sequence. Table 1contains the clone names of full-length cDNA of 1970 clones of thepresent invention, SEQ ID NOs of the full-length nucleotide sequences,CDS portions deduced from the full-length nucleotide sequences, and SEQID NOs of the translated amino acids. The positions of CDS are shownaccording to the rule of “DDBJ/EMBL/GenBank Feature Table Definition”(http://www.ncbi.nlm.nih.gov/collab/FT/index.html). The start positionnumber corresponds to the first letter of “ATG” that is the nucleotidetriplet encoding methionine; the termination position number correspondsto the third letter of the stop codon. These are indicated being flankedwith the mark “ . . . ”. However, with respect to the clones having nostop codon, the termination position is indicated by the mark “>”according to the above rule. TABLE 1 SEQ ID NO. SEQ ID NO. Clone ofnucleotide Position of amino acid name sequence of CDS sequenceADRGL20020290 1  62 . . . 1669 1971 ADRGL20021910 2 150 . . . 707 1972ADRGL20022600 3 464 . . . 814 1973 ADRGL20023920 4  375 . . . 1853 1974ADRGL20026790 5  113 . . . 2371 1975 ADRGL20027530 6 2013 . . . 23721976 ADRGL20036380 7 1129 . . . 1557 1977 ADRGL20036840 8 260 . . . 8891978 ADRGL20040310 9 539 . . . 844 1979 ADRGL20040770 10  817 . . . 12271980 ADRGL20046760 11 1108 . . . 1467 1981 ADRGL20047080 12  823 . . .1134 1982 ADRGL20047770 13 1532 . . . 1897 1983 ADRGL20057560 14 376 . .. 846 1984 ADRGL20059610 15  969 . . . 1961 1985 ADRGL20062330 16    799. . . >2117 1986 ADRGL20063770 17 344 . . . 664 1987 ADRGL20066770 18 22 . . . 1416 1988 ADRGL20067320 19  276 . . . 1016 1989 ADRGL2007906020  63 . . . 1748 1990 ADRGL20095330 21  929 . . . 1516 1991ASTRO20001910 22   1753 . . . >2216 1992 ASTRO20003720 23 2089 . . .2586 1993 ASTRO20004820 24  444 . . . 1040 1994 ASTRO20006530 25   2 . .. 1123 1995 ASTRO20009140 26  344 . . . 1714 1996 ASTRO20010010 27 1236. . . 1727 1997 ASTRO20010290 28  2 . . . 745 1998 ASTRO20012270 29 286. . . 627 1999 ASTRO20020240 30  12 . . . 335 2000 ASTRO20020350 31 1384. . . 1854 2001 ASTRO20022020 32  467 . . . 1093 2002 ASTRO20026320 33 473 . . . 2161 2003 ASTRO20027330 34  481 . . . 1101 2004 ASTRO2003840035  52 . . . 2025 2005 ASTRO20045840 36  263 . . . 1051 2006ASTRO20046280 37  140 . . . 1402 2007 ASTRO20047510 38 1240 . . . 16112008 ASTRO20050810 39  171 . . . 1694 2009 ASTRO20052420 40 1166 . . .2362 2010 ASTRO20053430 41  218 . . . 1885 2011 ASTRO20055530 42 209 . .. 559 2012 ASTRO20055570 43 242 . . . 733 2013 ASTRO20055930 44  343 . .. 1086 2014 ASTRO20058960 45  55 . . . 1215 2015 ASTRO20069200 46  71 .. . 1237 2016 ASTRO20075150 47 1004 . . . 1795 2017 ASTRO20076660 481594 . . . 1968 2018 ASTRO20085080 49  470 . . . 2011 2019 ASTRO2008895050  346 . . . 1530 2020 ASTRO20089600 51  142 . . . 1125 2021ASTRO20090680 52   1221 . . . >2631 2022 ASTRO20091180 53  12 . . . 12142023 ASTRO20091770 54  10 . . . 318 2024 ASTRO20141740 55  30 . . . 3472025 BGGI120000670 56 240 . . . 614 2026 BGGI120010750 57    72 . .. >2507 2027 BNGH410000570 58  957 . . . 2027 2028 BNGH420008150 59  596. . . 1606 2029 BNGH420014060 60 1072 . . . 1413 2030 BNGH420015760 61 92 . . . 1336 2031 BNGH420021680 62  147 . . . 2093 2032 BNGH42002387063  301 . . . 1851 2033 BNGH420024870 64  155 . . . 1960 2034BNGH420035290 65  114 . . . 2126 2035 BNGH420036410 66 1778 . . . 21432036 BNGH420040760 67  698 . . . 1162 2037 BNGH420042910 68 191 . . .721 2038 BNGH420045380 69  721 . . . 1254 2039 BNGH420046790 70 1079 . .. 1429 2040 BNGH420052350 71  787 . . . 1146 2041 BNGH420059680 72  213. . . 2393 2042 BNGH420061350 73  600 . . . 3131 2043 BNGH420062340 74294 . . . 641 2044 BNGH420070370 75  567 . . . 2429 2045 BNGH42007460076  125 . . . 1696 2046 BNGH420075940 77  31 . . . 510 2047BNGH420077980 78  288 . . . 2147 2048 BNGH420085100 79 243 . . . 5692049 BNGH420086030 80    107 . . . >2556 2050 BNGH420087430 81  195 . .. 1835 2051 BRACE10000510 82  642 . . . 1703 2052 BRACE20003310 83 1379. . . 2893 2053 BRACE20007330 84  339 . . . 2015 2054 BRACE20009050 851023 . . . 1493 2055 BRACE20014450 86  161 . . . 1096 2056 BRACE2001779087 304 . . . 639 2057 BRACE20018810 88  397 . . . 1146 2058BRACE20025820 89 453 . . . 767 2059 BRACE20038920 90 1122 . . . 14632060 BRACE20050870 91  110 . . . 1987 2061 BRACE20051600 92 443 . . .895 2062 BRACE20051930 93 173 . . . 901 2063 BRACE20052430 94  825 . . .1637 2064 BRACE20052530 95  98 . . . 490 2065 BRACE20054080 96  762 . .. 1382 2066 BRACE20054480 97 111 . . . 902 2067 BRACE20054600 98  392 .. . 1276 2068 BRACE20055560 99 136 . . . 735 2069 BRACE20057870 100 1169. . . 1825 2070 BRACE20059110 101 1452 . . . 1910 2071 BRACE20059810 102 689 . . . 2218 2072 BRACE20061620 103  162 . . . 1163 2073BRACE20062580 104 1164 . . . 1859 2074 BRACE20063540 105  378 . . . 16702075 BRACE20065470 106  427 . . . 1101 2076 BRACE20066360 107 233 . . .736 2077 BRACE20068710 108 1099 . . . 1440 2078 BRACE20069000 109 1355 .. . 2305 2079 BRACE20069110 110 576 . . . 917 2080 BRACE20069440 111 278 . . . 1504 2081 BRACE20079200 112  928 . . . 1413 2082BRACE20079370 113  158 . . . 1522 2083 BRACE20097540 114 1474 . . . 21032084 BRACE20098860 115  693 . . . 1193 2085 BRACE20099070 116  53 . . .1441 2086 BRACE20194670 117  11 . . . 616 2087 BRACE20196180 118  35 . .. 916 2088 BRACE20196960 119 1454 . . . 1912 2089 BRACE20200770 120 306. . . 683 2090 BRACE20200970 121 426 . . . 764 2091 BRACE20204670 122 760 . . . 2124 2092 BRACE20205840 123  40 . . . 387 2093 BRACE20207420124 119 . . . 469 2094 BRACE20212450 125 168 . . . 590 2095BRACE20215410 126  111 . . . 1361 2096 BRACE20216700 127 1403 . . . 17382097 BRACE20216950 128  911 . . . 1315 2098 BRACE20219360 129 198 . . .596 2099 BRAMY10000980 130 254 . . . 616 2100 BRAMY10001730 131  796 . .. 1158 2101 BRAMY20000210 132 134 . . . 445 2102 BRAMY20000250 133  190. . . 1932 2103 BRAMY20001510 134 129 . . . 917 2104 BRAMY20003540 135 144 . . . 2477 2105 BRAMY20003880 136 191 . . . 808 2106 BRAMY20005080137 1638 . . . 1958 2107 BRAMY20013670 138  551 . . . 2881 2108BRAMY20016780 139  273 . . . 1985 2109 BRAMY20020440 140 359 . . . 6852110 BRAMY20021580 141  67 . . . 555 2111 BRAMY20023390 142 1568 . . .1939 2112 BRAMY20023640 143 1684 . . . 2280 2113 BRAMY20024790 144 276 .. . 626 2114 BRAMY20027390 145 420 . . . 782 2115 BRAMY20027990 146  529. . . 1572 2116 BRAMY20028530 147  973 . . . 1278 2117 BRAMY20028620 1481048 . . . 1434 2118 BRAMY20035380 149  925 . . . 1707 2119BRAMY20035830 150 219 . . . 977 2120 BRAMY20036530 151 1411 . . . 17612121 BRAMY20036810 152 321 . . . 644 2122 BRAMY20038980 153    715 . .. >2057 2123 BRAMY20039290 154  81 . . . 1043 2124 BRAMY20040580 155 374. . . 769 2125 BRAMY20043520 156  942 . . . 1778 2126 BRAMY20043630 157 25 . . . 1119 2127 BRAMY20044920 158  40 . . . 1947 2128 BRAMY20045210159 367 . . . 750 2129 BRAMY20045420 160  4 . . . 888 2130 BRAMY20047560161 220 . . . 726 2131 BRAMY20050640 162 1802 . . . 2635 2132BRAMY20050940 163  23 . . . 385 2133 BRAMY20051820 164 1411 . . . 21572134 BRAMY20052440 165  29 . . . 448 2135 BRAMY20053910 166  11 . . .358 2136 BRAMY20055760 167  664 . . . 2253 2137 BRAMY20056620 168  46 .. . 726 2138 BRAMY20056840 169  40 . . . 1392 2139 BRAMY20063750 170 535 . . . 2166 2140 BRAMY20072440 171  823 . . . 1620 2141BRAMY20072870 172 437 . . . 910 2142 BRAMY20073080 173  3 . . . 353 2143BRAMY20074110 174 314 . . . 838 2144 BRAMY20074860 175 1135 . . . 15242145 BRAMY20076100 176  459 . . . 1019 2146 BRAMY20076130 177  59 . . .376 2147 BRAMY20076530 178 1010 . . . 1465 2148 BRAMY20083330 179  10 .. . 492 2149 BRAMY20083820 180  625 . . . 1113 2150 BRAMY20089770 181173 . . . 955 2151 BRAMY20091230 182  818 . . . 1579 2152 BRAMY20093490183  637 . . . 1080 2153 BRAMY20094890 184  30 . . . 2138 2154BRAMY20095080 185 239 . . . 613 2155 BRAMY20095570 186 109 . . . 8072156 BRAMY20096930 187 1381 . . . 1800 2157 BRAMY20100680 188 268 . . .870 2158 BRAMY20102900 189 200 . . . 760 2159 BRAMY20107980 190 343 . .. 669 2160 BRAMY20111780 191  584 . . . 2209 2161 BRAMY20117670 192  63. . . 782 2162 BRAMY20118410 193  24 . . . 782 2163 BRAMY20118490 194 39 . . . 791 2164 BRAMY20120170 195 1130 . . . 1459 2165 BRAMY20123400196 1420 . . . 1755 2166 BRAMY20124970 197  825 . . . 1226 2167BRAMY20125170 198 157 . . . 579 2168 BRAMY20125360 199  134 . . . 10602169 BRAMY20125550 200  29 . . . 1747 2170 BRAMY20126910 201 114 . . .518 2171 BRAMY20127310 202 1986 . . . 2336 2172 BRAMY20127760 203 317 .. . 691 2173 BRAMY20134050 204 199 . . . 522 2174 BRAMY20135720 205  57. . . 401 2175 BRAMY20137360 206  976 . . . 2193 2176 BRAMY20139440 207  2 . . . 1597 2177 BRAMY20139750 208  88 . . . 435 2178 BRAMY20143870209 1419 . . . 2102 2179 BRAMY20152510 210  296 . . . 1993 2180BRAMY20155500 211  722 . . . 1069 2181 BRAMY20158550 212 142 . . . 9512182 BRAMY20159250 213 286 . . . 810 2183 BRAMY20160020 214 143 . . .919 2184 BRAMY20173480 215 1544 . . . 1906 2185 BRAMY20190550 216  114 .. . 1640 2186 BRAMY20194680 217 1179 . . . 1517 2187 BRAMY20204270 218218 . . . 844 2188 BRAMY20206340 219  237 . . . 1805 2189 BRAMY20219620220 1014 . . . 1670 2190 BRAMY20221600 221 168 . . . 992 2191BRAMY20223010 222  466 . . . 1257 2192 BRAMY20225250 223 368 . . . 6732193 BRAMY20225320 224 241 . . . 840 2194 BRAMY20227230 225 1327 . . .2067 2195 BRAMY20227860 226  10 . . . 657 2196 BRAMY20227960 227 1148 .. . 1558 2197 BRAMY20231150 228  199 . . . 1146 2198 BRAMY20234820 229 199 . . . 2079 2199 BRAMY20237190 230 397 . . . 870 2200 BRAMY20238630231  303 . . . 1331 2201 BRAMY20243120 232 1756 . . . 2451 2202BRAMY20244490 233 257 . . . 982 2203 BRAMY20245140 234   3 . . . 12952204 BRAMY20245350 235  94 . . . 750 2205 BRAMY20245760 236  35 . . .1375 2206 BRAMY20251210 237  68 . . . 955 2207 BRAMY20251750 238  97 . .. 846 2208 BRAMY20263000 239  216 . . . 1553 2209 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CTONG20017490 319  346 . . . 2235 2289 CTONG20020660 320 219 . . .635 2290 CTONG20020950 321  24 . . . 3257 2291 CTONG20027660 322 103 . .. 942 2292 CTONG20029030 323  102 . . . 2492 2293 CTONG20030280 324  219. . . 2891 2294 CTONG20031150 325 2175 . . . 2546 2295 CTONG20031890 326  8 . . . 1705 2296 CTONG20032930 327  352 . . . 3102 2297 CTONG20033500328 1683 . . . 2018 2298 CTONG20033610 329    404 . . . >3203 2299CTONG20033750 330  95 . . . 1999 2300 CTONG20035240 331  234 . . . 26872301 CTONG20036800 332 432 . . . 770 2302 CTONG20036990 333 1568 . . .2347 2303 CTONG20039370 334 114 . . . 470 2304 CTONG20041150 335  406 .. . 1164 2305 CTONG20041260 336  477 . . . 2276 2306 CTONG20042640 337  6 . . . 2381 2307 CTONG20044230 338 1199 . . . 3205 2308 CTONG20044870339  17 . . . 2554 2309 CTONG20045500 340  226 . . . 1950 2310CTONG20046690 341 385 . . . 840 2311 CTONG20049480 342    216 . .. >3268 2312 CTONG20050490 343 428 . . . 859 2313 CTONG20051100 344  48. . . 419 2314 CTONG20051450 345 1239 . . . 1823 2315 CTONG20052780 346 976 . . . 1656 2316 CTONG20053990 347   2233 . . . >2955 2317CTONG20055670 348 2306 . . . 2620 2318 CTONG20055850 349  506 . . . 12462319 CTONG20056150 350  95 . . . 1150 2320 CTONG20057750 351 2355 . . .2849 2321 CTONG20057950 352 3061 . . . 3420 2322 CTONG20059130 353  109. . . 2613 2323 CTONG20060040 354  204 . . . 2630 2324 CTONG20061290 355226 . . . 819 2325 CTONG20062730 356 307 . . . 687 2326 CTONG20063770357  108 . . . 3203 2327 CTONG20063930 358  250 . . . 2700 2328CTONG20065240 359 1983 . . . 2333 2329 CTONG20065680 360 2369 . . . 27972330 CTONG20066110 361  122 . . . 1972 2331 CTONG20068360 362 1136 . . .1876 2332 CTONG20069320 363  843 . . . 1238 2333 CTONG20069420 364 130 .. . 600 2334 CTONG20070090 365  561 . . . 2960 2335 CTONG20070720 366 431 . . . 2677 2336 CTONG20070780 367   2 . . . 2896 2337 CTONG20070910368  87 . . . 1397 2338 CTONG20071040 369  16 . . . 1551 2339CTONG20071680 370    189 . . . >2419 2340 CTONG20072930 371 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2367 CTONG20174290 398  96 . . . 1826 2368 CTONG20174440 3991246 . . . 1623 2369 CTONG20174580 400   1 . . . 1023 2370 CTONG20176040401 147 . . . 737 2371 CTONG20179390 402 1423 . . . 1881 2372CTONG20179890 403  335 . . . 2344 2373 CTONG20179980 404 1821 . . . 22102374 CTONG20180620 405 1556 . . . 1915 2375 CTONG20180690 406  366 . . .1442 2376 CTONG20181350 407 1167 . . . 1607 2377 CTONG20183430 408  319. . . 2706 2378 CTONG20183830 409  393 . . . 2687 2379 CTONG20184130 4101970 . . . 2536 2380 CTONG20184830 411  323 . . . 1204 2381CTONG20186140 412  21 . . . 443 2382 CTONG20186290 413 2170 . . . 28112383 CTONG20186370 414  156 . . . 1244 2384 CTONG20186520 415  211 . . .2136 2385 CTONG20186550 416 260 . . . 811 2386 CTONG20188080 417  207 .. . 2774 2387 CTONG20189000 418  174 . . . 1682 2388 CTONG20190290 419 220 . . . 2205 2389 CTONG20190630 420  34 . . . 2082 2390 DFNES20016470421 288 . . . 851 2391 DFNES20018000 422  40 . . . 1596 2392DFNES20025500 423  766 . . . 1134 2393 DFNES20028170 424  289 . . . 17342394 DFNES20029660 425  356 . . . 2443 2395 DFNES20032550 426  35 . . .931 2396 DFNES20043710 427 108 . . . 929 2397 DFNES20046840 428  786 . .. 1310 2398 DFNES20055400 429  343 . . . 1584 2399 DFNES20057660 430  25. . . 795 2400 DFNES20063460 431  26 . . . 406 2401 DFNES20072990 432 62 . . . 1156 2402 DFNES20073320 433  377 . . . 1735 2403 DFNES20076340434 167 . . . 898 2404 DFNES20080880 435  11 . . . 1669 2405DFNES20088810 436 171 . . . 548 2406 DFNES20094820 437  107 . . . 18072407 FCBBF10000230 438  104 . . . 3247 2408 FCBBF10002200 439 480 . . .782 2409 FCBBF10004760 440  578 . . . 1978 2410 FCBBF20018680 441  177 .. . 1724 2411 FCBBF20020440 442 382 . . . 885 2412 FCBBF20021110 443 158. . . 517 2413 FCBBF20023490 444  64 . . . 1779 2414 FCBBF20028980 445 694 . . . 1014 2415 FCBBF20029280 446 1680 . . . 2021 2416FCBBF20032930 447  90 . . . 452 2417 FCBBF20033360 448  315 . . . 23692418 FCBBF20035430 449 196 . . . 726 2419 FCBBF20035490 450  131 . . .1387 2420 FCBBF20036360 451  16 . . . 366 2421 FCBBF20038230 452 1468 .. . 1908 2422 FCBBF20038950 453 648 . . . 992 2423 FCBBF20041380 454 612 . . . 2174 2424 FCBBF20043730 455    45 . . . >2063 2425FCBBF20054390 456 1367 . . . 1756 2426 FCBBF20056580 457    82 . .. >2394 2427 FCBBF20059660 458  672 . . . 1226 2428 FCBBF20061310 4591582 . . . 1980 2429 FCBBF20066340 460  116 . . . 1024 2430FCBBF20070800 461  968 . . . 1447 2431 FCBBF20070950 462    50 . .. >2299 2432 FCBBF30000010 463  74 . . . 643 2433 FCBBF30001020 464  16. . . 348 2434 FCBBF30001100 465    341 . . . >3125 2435 FCBBF30001150466 1209 . . . 1631 2436 FCBBF30002270 467 319 . . . 927 2437FCBBF30002280 468  113 . . . 4036 2438 FCBBF30002330 469  6 . . . 6112439 FCBBF30003610 470 1015 . . . 2019 2440 FCBBF30004340 471  120 . . .1013 2441 FCBBF30004730 472  368 . . . 1027 2442 FCBBF30005180 473  155. . . 2734 2443 FCBBF30005360 474  29 . . . 2710 2444 FCBBF30005500 475 251 . . . 2494 2445 FCBBF30019140 476  40 . . . 2979 2446 FCBBF30019180477  140 . . . 1669 2447 FCBBF30019240 478 1214 . . . 2269 2448FCBBF30021900 479  63 . . . 1973 2449 FCBBF30022680 480 1308 . . . 24802450 FCBBF30026580 481  170 . . . 2725 2451 FCBBF30029250 482  52 . . .4086 2452 FCBBF30035570 483    217 . . . >2468 2453 FCBBF30042610 484 33 . . . 1244 2454 FCBBF30048420 485  144 . . . 1094 2455 FCBBF30053300486  62 . . . 2182 2456 FCBBF30056980 487 1098 . . . 1415 2457FCBBF30062490 488  128 . . . 1063 2458 FCBBF30063990 489 250 . . . 8282459 FCBBF30068210 490  51 . . . 2762 2460 FCBBF30071500 491    227 . .. >2898 2461 FCBBF30072440 492 2485 . . . 2865 2462 FCBBF30072480 493  2602 . . . >3057 2463 FCBBF30074530 494 1031 . . . 1432 2464FCBBF30074620 495  840 . . . 1316 2465 FCBBF30075970 496 146 . . . 4602466 FCBBF30076310 497  42 . . . 1007 2467 FCBBF30078600 498  113 . . .1399 2468 FCBBF30079770 499  693 . . . 2777 2469 FCBBF30080730 500  54 .. . 467 2470 FCBBF30081000 501 526 . . . 924 2471 FCBBF30085560 502  60. . . 1919 2472 FCBBF30088700 503    39 . . . >3015 2473 FCBBF30089380504   8 . . . 2701 2474 FCBBF30091010 505    172 . . . >3465 2475FCBBF30091520 506  56 . . . 2284 2476 FCBBF30093170 507  974 . . . 15282477 FCBBF30095410 508  64 . . . 1002 2478 FCBBF30099490 509 2939 . . .3256 2479 FCBBF30100080 510 1237 . . . 1656 2480 FCBBF30100120 511   8 .. . 2305 2481 FCBBF30100410 512  121 . . . 1374 2482 FCBBF30101240 5131696 . . . 2382 2483 FCBBF30101300 514   3802 . . . >4413 2484FCBBF30105080 515  973 . . . 1836 2485 FCBBF30105440 516 1354 . . . 20402486 FCBBF30105860 517    355 . . . >2524 2487 FCBBF30106950 518 192 . .. 944 2488 FCBBF30107290 519 1002 . . . 1610 2489 FCBBF30107330 520  703. . . 1071 2490 FCBBF30114180 521 1777 . . . 2289 2491 FCBBF30114850 522 769 . . . 1503 2492 FCBBF30115230 523 417 . . . 755 2493 FCBBF30115920524  543 . . . 1802 2494 FCBBF30118670 525  891 . . . 2807 2495FCBBF30118890 526    184 . . . >2630 2496 FCBBF30125460 527  67 . . .1926 2497 FCBBF30125880 528 185 . . . 670 2498 FCBBF30128420 529 1789 .. . 2130 2499 FCBBF30129010 530  184 . . . 1236 2500 FCBBF30130410 5311149 . . . 1874 2501 FCBBF30130580 532  156 . . . 2123 2502FCBBF30132050 533  718 . . . 1854 2503 FCBBF30132660 534  86 . . . 10512504 FCBBF30135890 535    214 . . . >2483 2505 FCBBF30136230 536  24 . .. 3338 2506 FCBBF30138000 537  646 . . . 2901 2507 FCBBF30142290 538 679 . . . 1662 2508 FCBBF30143550 539  111 . . . 3191 2509FCBBF30145670 540 1533 . . . 1880 2510 FCBBF30151190 541  974 . . . 13122511 FCBBF30153170 542  16 . . . 2307 2512 FCBBF30157270 543    84 . .. >3303 2513 FCBBF30161780 544  21 . . . 659 2514 FCBBF30164510 545  561. . . 3035 2515 FCBBF30166220 546 178 . . . 483 2516 FCBBF30169280 547116 . . . 901 2517 FCBBF30169870 548 102 . . . 407 2518 FCBBF30170710549  8 . . . 382 2519 FCBBF30171230 550 1735 . . . 2361 2520FCBBF30172330 551 2497 . . . 2952 2521 FCBBF30173960 552    106 . .. >3530 2522 FCBBF30175350 553  2 . . . 721 2523 FCBBF30177290 554 378 .. . 923 2524 FCBBF30179180 555   2382 . . . >3452 2525 FCBBF30179740 556299 . . . 721 2526 FCBBF30181730 557  43 . . . 351 2527 FCBBF30194370558  698 . . . 1057 2528 FCBBF30194550 559   9 . . . 1982 2529FCBBF30195690 560  15 . . . 1682 2530 FCBBF30195700 561  14 . . . 3762531 FCBBF30197840 562  406 . . . 3015 2532 FCBBF30198670 563  421 . . .2733 2533 FCBBF30201630 564 1407 . . . 2561 2534 FCBBF30212210 565 1669. . . 2502 2535 FCBBF30215240 566  774 . . . 1586 2536 FCBBF30220050 5671431 . . . 2006 2537 FCBBF30222910 568 117 . . . 614 2538 FCBBF30223110569  647 . . . 1129 2539 FCBBF30223210 570 141 . . . 680 2540FCBBF30225930 571  166 . . . 1956 2541 FCBBF30228940 572  79 . . . 4532542 FCBBF30230610 573  99 . . . 440 2543 FCBBF30236670 574 1889 . . .2719 2544 FCBBF30250980 575  214 . . . 2514 2545 FCBBF30255680 576    27. . . >2480 2546 FCBBF30257370 577   2 . . . 1873 2547 FCBBF30259050 578 104 . . . 1600 2548 FCBBF30260210 579    115 . . . >2494 2549FCBBF30260480 580  28 . . . 519 2550 FCBBF30263080 581 535 . . . 9002551 FCBBF30266510 582  445 . . . 3378 2552 FCBBF30271990 583  187 . . .1704 2553 FCBBF30275590 584    51 . . . >2374 2554 FCBBF30282020 585 123 . . . 1721 2555 FCBBF30285930 586 260 . . . 697 2556 FCBBF30287940587 1636 . . . 2079 2557 FCBBF40000610 588  586 . . . 1131 2558FCBBF40001920 589  753 . . . 1082 2559 FCBBF40005000 590  57 . . . 4462560 FCBBF50000410 591  930 . . . 1256 2561 FCBBF50000610 592 383 . . .697 2562 FCBBF50001650 593  562 . . . 1815 2563 FCBBF50003530 594 127 .. . 921 2564 FCBBF50004950 595 2156 . . . 2545 2565 FEBRA20005040 596 295 . . . 2100 2566 FEBRA20007820 597 160 . . . 690 2567 FEBRA20018670598  184 . . . 1077 2568 FEBRA20026820 599  103 . . . 1836 2569FEBRA20027070 600  663 . . . 1736 2570 FEBRA20029620 601  565 . . . 12062571 FEBRA20031000 602  380 . . . 2551 2572 FEBRA20031150 603 2925 . . .3293 2573 FEBRA20031280 604  362 . . . 3124 2574 FEBRA20031810 605 1093. . . 1455 2575 FEBRA20035200 606 2607 . . . 3215 2576 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633 1302 . . . 2021 2603 FEBRA20090160 634  1 . .. 732 2604 FEBRA20090220 635  106 . . . 2271 2605 FEBRA20091620 636 1528. . . 1935 2606 FEBRA20092760 637  694 . . . 1317 2607 FEBRA20093270 6382205 . . . 2507 2608 FEBRA20093280 639 2165 . . . 2485 2609FEBRA20095410 640 267 . . . 647 2610 FEBRA20098040 641  43 . . . 4592611 FEBRA20099860 642  55 . . . 573 2612 FEBRA20101410 643 396 . . .740 2613 FEBRA20108020 644 181 . . . 492 2614 FEBRA20108580 645 542 . .. 901 2615 FEBRA20115930 646  58 . . . 1494 2616 FEBRA20116650 647 178 .. . 573 2617 FEBRA20121200 648  972 . . . 1490 2618 FEBRA20121950 6491217 . . . 1723 2619 FEBRA20141980 650 644 . . . 955 2620 FEBRA20150420651  314 . . . 3124 2621 FEBRA20151750 652    52 . . . >2299 2622FEBRA20163980 653  93 . . . 1223 2623 FEBRA20170240 654  385 . . . 16322624 FEBRA20172230 655  377 . . . 1363 2625 FEBRA20173330 656  462 . . .2378 2626 FEBRA20175020 657 2040 . . . 2438 2627 FEBRA20175330 658  62 .. . 520 2628 FEBRA20177800 659 1918 . . . 2289 2629 FEBRA20180510 660350 . . . 889 2630 FEBRA20182030 661 341 . . . 745 2631 FEBRA20187460662 395 . . . 736 2632 FEBRA20191720 663 417 . . . 836 2633HCHON10000150 664 197 . . . 670 2634 HCHON10001660 665  913 . . . 13382635 HCHON20000870 666  442 . . . 1857 2636 HCHON20002650 667  4 . . .792 2637 HCHON20002710 668  169 . . . 1437 2638 HCHON20015050 669  529 .. . 1995 2639 HEART10001420 670   4 . . . 1476 2640 HEART10001490 671 159 . . . 1121 2641 HEART20009590 672 1369 . . . 1938 2642HEART20019310 673  47 . . . 1693 2643 HEART20022200 674  11 . . . 13782644 HEART20031680 675 1033 . . . 3018 2645 HEART20047640 676  595 . . .2904 2646 HEART20063100 677 131 . . . 826 2647 HEART20082570 678  18 . .. 1022 2648 HHDPC10001140 679  506 . . . 1102 2649 HHDPC20051850 680  21. . . 422 2650 HHDPC20081230 681  132 . . . 2195 2651 HHDPC20082790 682150 . . . 608 2652 HHDPC20082970 683 1445 . . . 1771 2653 HHDPC20088160684    214 . . . >2639 2654 HLUNG20008460 685  157 . . . 1818 2655HLUNG20009260 686 1035 . . . 1856 2656 HLUNG20009550 687  16 . . . 6572657 HLUNG20010130 688 1083 . . . 1400 2658 HLUNG20011260 689 135 . . .479 2659 HLUNG20011440 690  803 . . . 1207 2660 HLUNG20011460 691  43 .. . 1587 2661 HLUNG20012140 692 188 . . . 508 2662 HLUNG20014590 693  1015 . . . >2241 2663 HLUNG20015070 694  377 . . . 1945 2664HLUNG20015180 695  468 . . . 1808 2665 HLUNG20020500 696 1232 . . . 16872666 HLUNG20020850 697  802 . . . 1179 2667 HLUNG20021450 698  753 . . .1109 2668 HLUNG20023030 699 2466 . . . 2855 2669 HLUNG20024050 700  651. . . 1568 2670 HLUNG20025620 701 1424 . . . 1765 2671 HLUNG20028110 702 164 . . . 1996 2672 HLUNG20029420 703 160 . . . 774 2673 HLUNG20029490704 135 . . . 563 2674 HLUNG20030420 705  116 . . . 1906 2675HLUNG20030490 706  553 . . . 1608 2676 HLUNG20030610 707  920 . . . 14652677 HLUNG20031620 708  604 . . . 1038 2678 HLUNG20032460 709  29 . . .1582 2679 HLUNG20033060 710   1085 . . . >2287 2680 HLUNG20033310 7111319 . . . 1654 2681 HLUNG20033350 712   1035 . . . >2205 2682HLUNG20034970 713 1046 . . . 1747 2683 HLUNG20037140 714 1342 . . . 16982684 HLUNG20037160 715 1704 . . . 3152 2685 HLUNG20037780 716 1190 . . .1855 2686 HLUNG20038330 717  433 . . . 1284 2687 HLUNG20041540 718  199. . . 1542 2688 HLUNG20041590 719    130 . . . >2341 2689 HLUNG20042730720  150 . . . 1484 2690 HLUNG20045340 721 189 . . . 608 2691HLUNG20047070 722 1310 . . . 1672 2692 HLUNG20050760 723 1813 . . . 21182693 HLUNG20051330 724    55 . . . >2821 2694 HLUNG20052300 725  88 . .. 1008 2695 HLUNG20054790 726 1418 . . . 2548 2696 HLUNG20055240 727 204. . . 554 2697 HLUNG20056560 728  6 . . . 512 2698 HLUNG20057380 729 303. . . 788 2699 HLUNG20059240 730 1529 . . . 1870 2700 HLUNG20060670 731 753 . . . 1517 2701 HLUNG20063700 732 1356 . . . 1685 2702HLUNG20065700 733  90 . . . 911 2703 HLUNG20065990 734  344 . . . 12312704 HLUNG20067810 735 178 . . . 639 2705 HLUNG20068120 736  853 . . .1281 2706 HLUNG20069350 737  198 . . . 1871 2707 HLUNG20070410 738 474 .. . 929 2708 HLUNG20072100 739  164 . . . 1879 2709 HLUNG20072190 7401394 . . . 1723 2710 HLUNG20072450 741 127 . . . 468 2711 HLUNG20074330742   1621 . . . >1976 2712 HLUNG20079310 743 1484 . . . 2050 2713HLUNG20081390 744  123 . . . 1910 2714 HLUNG20081530 745 1218 . . . 18892715 HLUNG20082350 746  313 . . . 2109 2716 HLUNG20083330 747  770 . . .1138 2717 HLUNG20083480 748  183 . . . 1895 2718 HLUNG20083840 749 1389. . . 1811 2719 HLUNG20083960 750 1214 . . . 1630 2720 HLUNG20084790 7511185 . . . 1745 2721 HLUNG20085210 752 138 . . . 779 2722 HLUNG20088750753 1321 . . . 1635 2723 HLUNG20092530 754 224 . . . 577 2724HLUNG20093030 755 1836 . . . 2246 2725 HLUNG20094130 756 2129 . . . 25542726 KIDNE20011600 757 197 . . . 601 2727 KIDNE20016360 758  81 . . .2798 2728 KIDNE20024380 759   1017 . . . >1994 2729 KIDNE20027980 760 329 . . . 1891 2730 KIDNE20080690 761   1 . . . 1500 2731 KIDNE20081170762 1356 . . . 2444 2732 KIDNE20083150 763  863 . . . 1342 2733KIDNE20083620 764  216 . . . 1142 2734 KIDNE20084030 765  28 . . . 15722735 KIDNE20084040 766 318 . . . 926 2736 KIDNE20084730 767  580 . . .2511 2737 KIDNE20084800 768  9 . . . 332 2738 KIDNE20086490 769  162 . .. 1919 2739 KIDNE20086660 770 341 . . . 700 2740 KIDNE20086970 771 202 .. . 846 2741 KIDNE20087880 772  668 . . . 1003 2742 KIDNE20088240 773 101 . . . 1135 2743 KIDNE20089870 774  212 . . . 1621 2744KIDNE20091090 775 272 . . . 670 2745 KIDNE20094260 776 125 . . . 4422746 KIDNE20094670 777  997 . . . 2232 2747 KIDNE20095530 778   1573 . .. >1878 2748 KIDNE20133460 779    210 . . . >1556 2749 KIDNE20133880 780 743 . . . 1057 2750 KIDNE20134130 781 174 . . . 797 2751 KIDNE20134890782 384 . . . 923 2752 KIDNE20137310 783 304 . . . 876 2753KIDNE20138450 784 499 . . . 828 2754 KIDNE20140870 785    750 . .. >3206 2755 KIDNE20141120 786 1387 . . . 1932 2756 KIDNE20141700 7871825 . . . 2286 2757 KIDNE20142680 788  796 . . . 1239 2758KIDNE20142900 789  45 . . . 764 2759 KIDNE20143200 790  982 . . . 14522760 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LIVER20007690 817 329 . . . 760 2787 LIVER20007750818  176 . . . 1549 2788 LIVER20010510 819  757 . . . 1143 2789LIVER20010760 820  95 . . . 838 2790 LIVER20010990 821  305 . . . 10092791 LIVER20011640 822 1187 . . . 2086 2792 LIVER20013890 823 1528 . . .2199 2793 LIVER20026440 824 1019 . . . 1963 2794 LIVER20030650 825 1469. . . 2239 2795 LIVER20032340 826 2181 . . . 2504 2796 LIVER20038000 827 78 . . . 1004 2797 LIVER20040740 828  195 . . . 1370 2798 LIVER20055270829  148 . . . 1347 2799 MESAN20006200 830 2690 . . . 3235 2800MESAN20007110 831 1401 . . . 1823 2801 MESAN20008150 832  136 . . . 35672802 MESAN20008940 833 122 . . . 514 2803 MESAN20009090 834  247 . . .1992 2804 MESAN20016270 835  346 . . . 2031 2805 MESAN20021130 836 1540. . . 2676 2806 MESAN20021220 837  94 . . . 2322 2807 MESAN20021470 838 658 . . . 1446 2808 MESAN20021860 839  217 . . . 1113 2809MESAN20026870 840  63 . . . 2450 2810 MESAN20027240 841  39 . . . 19402811 MESAN20027900 842  212 . . . 3322 2812 MESAN20029780 843 1900 . . .2331 2813 MESAN20030350 844    142 . . . >2239 2814 MESAN20030370 845 735 . . . 2462 2815 MESAN20030390 846  3 . . . 389 2816 MESAN20033220847  68 . . . 478 2817 MESAN20034440 848  42 . . . 2183 2818MESAN20038520 849  31 . . . 2547 2819 MESAN20041380 850  7 . . . 3422820 MESAN20045750 851  145 . . . 1002 2821 MESAN20056890 852  187 . . .1125 2822 MESAN20057240 853 101 . . . 778 2823 MESAN20058110 854  174 .. . 1022 2824 MESAN20059570 855  280 . . . 1782 2825 MESAN20060220 856464 . . . 775 2826 MESAN20060430 857 1589 . . . 3469 2827 MESAN20065990858 213 . . . 533 2828 MESAN20067430 859 1287 . . . 1973 2829MESAN20069530 860    336 . . . >3472 2830 MESAN20084150 861  78 . . .665 2831 MESAN20085360 862 1168 . . . 1656 2832 MESAN20089260 863  169 .. . 1254 2833 MESAN20090190 864  256 . . . 2898 2834 MESAN20094180 8651696 . . . 2139 2835 MESAN20095220 866 1118 . . . 1972 2836MESAN20095800 867  31 . . . 1137 2837 NESOP20004520 868  109 . . . 15122838 NESOP20005040 869  316 . . . 1308 2839 NT2NE20018740 870 1413 . . .1772 2840 NT2NE20018890 871  39 . . . 1061 2841 NT2NE20021860 872  268 .. . 1653 2842 NT2NE20026200 873 1888 . . . 2907 2843 NT2NE20026510 874 338 . . . 1381 2844 NT2NE20028700 875  166 . . . 1377 2845NT2NE20033150 876 496 . . . 912 2846 NT2NE20037050 877  19 . . . 4112847 NT2NE20038870 878  190 . . . 1548 2848 NT2NE20039210 879 226 . . .639 2849 NT2NE20042550 880  708 . . . 1568 2850 NT2NE20045190 881  33 .. . 599 2851 NT2NE20047870 882  314 . . . 1207 2852 NT2NE20053230 883 622 . . . 1068 2853 NT2NE20053950 884 133 . . . 993 2854 NT2NE20059210885  35 . . . 391 2855 NT2NE20059680 886 120 . . . 443 2856NT2NE20060750 887 239 . . . 928 2857 NT2NE20061030 888 160 . . . 6002858 NT2NE20062880 889 201 . . . 539 2859 NT2NE20064780 890  284 . . .1771 2860 NT2NE20066590 891  821 . . . 1204 2861 NT2NE20069580 892 1404. . . 2282 2862 NT2NE20070520 893 347 . . . 661 2863 NT2NE20073650 894 756 . . . 1088 2864 NT2NE20077250 895 1815 . . . 3185 2865NT2NE20077270 896    250 . . . >3642 2866 NT2NE20077860 897  589 . . .1053 2867 NT2NE20079670 898  404 . . . 1867 2868 NT2NE20080770 899 1181. . . 1483 2869 NT2NE20082130 900 1026 . . . 1457 2870 NT2NE20082600 901 688 . . . 1227 2871 NT2NE20086070 902 503 . . . 823 2872 NT2NE20087270903  276 . . . 1709 2873 NT2NE20087850 904  9 . . . 326 2874NT2NE20088030 905  682 . . . 1023 2875 NT2NE20092950 906  142 . . . 18842876 NT2NE20095230 907  547 . . . 1602 2877 NT2NE20104000 908 217 . . .702 2878 NT2NE20107810 909  29 . . . 376 2879 NT2NE20108420 910   1135 .. . >2525 2880 NT2NE20111190 911 202 . . . 651 2881 NT2NE20112210 912 963 . . . 2231 2882 NT2NE20114850 913   1441 . . . >1794 2883NT2NE20117580 914 271 . . . 912 2884 NT2NE20119980 915 445 . . . 8432885 NT2NE20123610 916 118 . . . 717 2886 NT2NE20124570 917 1279 . . .1620 2887 NT2NE20126030 918 1054 . . . 1548 2888 NT2NE20127900 919  85 .. . 1599 2889 NT2NE20140130 920 355 . . . 753 2890 NT2NE20140280 921 126. . . 989 2891 NT2NE20141040 922  53 . . . 811 2892 NT2NE20145250 923 94 . . . 531 2893 NT2NE20146510 924 125 . . . 661 2894 NT2NE20148690925 544 . . . 861 2895 NT2NE20149500 926 454 . . . 888 2896NT2NE20150610 927  73 . . . 432 2897 NT2NE20152620 928 1080 . . . 25162898 NT2NE20153620 929  133 . . . 1512 2899 NT2NE20155650 930  716 . . .1210 2900 NT2NE20157120 931  927 . . . 1271 2901 NT2NE20165190 932  85 .. . 531 2902 NT2NE20167660 933  20 . . . 349 2903 NT2NE20173970 934   274 . . . >2188 2904 NT2NE20177210 935 115 . . . 675 2905NT2NE20181760 936 201 . . . 785 2906 NT2NE20181800 937  784 . . . 11372907 NT2NE20184720 938 1033 . . . 1506 2908 NT2RI20016240 939 359 . . .748 2909 NT2RI20021200 940 534 . . . 875 2910 NT2RI20033920 941  269 . .. 1444 2911 NT2RI20093010 942 1478 . . . 1816 2912 NT2RP70001120 943 172 . . . 1518 2913 NT2RP70001730 944  166 . . . 1935 2914NT2RP70003110 945  15 . . . 1868 2915 NT2RP70012830 946  280 . . . 23372916 NT2RP70022820 947   2819 . . . >3760 2917 NT2RP70027790 948  389 .. . 2965 2918 NT2RP70029780 949  156 . . . 1349 2919 NT2RP70030840 950 278 . . . 2983 2920 NT2RP70031070 951  148 . . . 1740 2921NT2RP70031340 952  107 . . . 1576 2922 NT2RP70031480 953  203 . . . 29472923 NT2RP70035110 954 106 . . . 765 2924 NT2RP70046410 955  155 . . .1582 2925 NT2RP70049610 956  834 . . . 1889 2926 NT2RP70056290 957 2748. . . 3182 2927 NT2RP70056690 958    253 . . . >3053 2928 NT2RP70057500959  216 . . . 2615 2929 NT2RP70064570 960  636 . . . 2162 2930NT2RP70074800 961 199 . . . 684 2931 NT2RP70075300 962  226 . . . 15392932 NT2RP70075800 963  211 . . . 3801 2933 NT2RP70080150 964 306 . . .674 2934 NT2RP70084540 965  8 . . . 406 2935 NT2RP70087140 966  175 . .. 1074 2936 NT2RP70090870 967  272 . . . 2617 2937 NTONG20002230 968   50 . . . >3211 2938 NTONG20005310 969  88 . . . 471 2939NTONG20017620 970  40 . . . 432 2940 NTONG20029850 971  110 . . . 12582941 NTONG20031580 972 126 . . . 863 2942 NTONG20032100 973  65 . . .1132 2943 NTONG20034540 974  163 . . . 2523 2944 NTONG20035150 975  543. . . 2477 2945 NTONG20043080 976  22 . . . 2679 2946 NTONG20048440 977 89 . . . 1849 2947 NTONG20049180 978  155 . . . 1300 2948 NTONG20053630979  321 . . . 3821 2949 NTONG20053730 980  121 . . . 1701 2950NTONG20053910 981  47 . . . 2758 2951 NTONG20055200 982  122 . . . 19692952 NTONG20058010 983  237 . . . 1559 2953 NTONG20058220 984  67 . . .1314 2954 OCBBF20000740 985  165 . . . 2402 2955 OCBBF20001780 986 1990. . . 2334 2956 OCBBF20005220 987  590 . . . 2299 2957 OCBBF20009820 988281 . . . 823 2958 OCBBF20011860 989 145 . . . 528 2959 OCBBF20012520990  786 . . . 3023 2960 OCBBF20016390 991  667 . . . 1617 2961OCBBF20016810 992  123 . . . 2351 2962 OCBBF20109450 993 204 . . . 5062963 OCBBF20109780 994 253 . . . 573 2964 OCBBF20110210 995   8 . . .1072 2965 OCBBF20110730 996 1346 . . . 1666 2966 OCBBF20111370 997  296. . . 1345 2967 OCBBF20111600 998  375 . . . 1823 2968 OCBBF20112280 999447 . . . 860 2969 OCBBF20112320 1000  72 . . . 857 2970 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1052 1188 . . .1562 3022 PLACE60055460 1053  160 . . . 1197 3023 PLACE60055590 1054 123 . . . 1406 3024 PLACE60056910 1055 1028 . . . 1549 3025PLACE60057860 1056 1617 . . . 1940 3026 PLACE60061370 1057   1 . . .1899 3027 PLACE60062660 1058  97 . . . 954 3028 PLACE60062870 1059  604. . . 1278 3029 PLACE60063940 1060 459 . . . 797 3030 PLACE60064180 1061 167 . . . 1240 3031 PLACE60064740 1062 302 . . . 952 3032 PLACE600669701063  697 . . . 1998 3033 PLACE60068710 1064  363 . . . 1139 3034PLACE60069880 1065  898 . . . 1374 3035 PLACE60070500 1066  765 . . .1718 3036 PLACE60071800 1067  689 . . . 1333 3037 PLACE60072390 1068 145. . . 522 3038 PLACE60072420 1069 289 . . . 684 3039 PLACE60073090 1070 384 . . . 1814 3040 PLACE60074820 1071  38 . . . 727 3041 PLACE600778701072 2280 . . . 2609 3042 PLACE60080360 1073 285 . . . 938 3043PLACE60081260 1074 1192 . . . 1860 3044 PLACE60082850 1075  665 . . .1132 3045 PLACE60087680 1076  3 . . . 836 3046 PLACE60088240 1077  94 .. . 570 3047 PLACE60092280 1078 180 . . . 869 3048 PLACE60092370 1079371 . . . 691 3049 PLACE60093380 1080  433 . . . 1335 3050 PLACE600952401081  956 . . . 1312 3051 PLACE60095600 1082     4 . . . >2605 3052PLACE60098350 1083  86 . . . 1852 3053 PLACE60104630 1084 1267 . . .1671 3054 PLACE60105680 1085 1290 . . . 1631 3055 PLACE60107010 1086 128. . . 829 3056 PLACE60109910 1087  4 . . . 567 3057 PLACE60113340 1088 127 . . . 1518 3058 PLACE60118810 1089  101 . . . 1657 3059PLACE60119700 1090 199 . . . 516 3060 PLACE60120280 1091  61 . . . 7053061 PLACE60122970 1092    861 . . . >1396 3062 PLACE60132200 1093  240. . . 1082 3063 PLACE60132320 1094  471 . . . 1121 3064 PLACE601328801095  495 . . . 1406 3065 PLACE60138840 1096  729 . . . 1553 3066PLACE60140640 1097  840 . . . 1919 3067 PLACE60150510 1098  215 . . .1246 3068 PLACE60154450 1099  25 . . . 873 3069 PLACE60155910 1100 255 .. . 701 3070 PLACE60157310 1101 1156 . . . 1482 3071 PLACE60162100 1102 885 . . . 1226 3072 PLACE60175640 1103 242 . . . 556 3073 PLACE601778801104  104 . . . 1327 3074 PLACE60177910 1105  59 . . . 442 3075PLACE60181870 1106 131 . . . 673 3076 PLACE60184410 1107  995 . . . 14833077 PLACE60184870 1108    86 . . . >1402 3078 PLACE60188630 1109  571 .. . 1395 3079 PROST10001100 1110  716 . . . 1219 3080 PROST10001360 11111506 . . . 1997 3081 PROST10002150 1112  840 . . . 2345 3082PROST20007170 1113  216 . . . 1679 3083 PROST20007600 1114  29 . . . 7423084 PROST20011160 1115 150 . . . 548 3085 PROST20011800 1116 1297 . . .1629 3086 PROST20014140 1117 1901 . . . 3022 3087 PROST20014150 11181632 . . . 1961 3088 PROST20014650 1119 1243 . . . 1653 3089PROST20015210 1120  711 . . . 1499 3090 PROST20015400 1121  49 . . . 3993091 PROST20016760 1122  62 . . . 1870 3092 PROST20022120 1123 301 . . .762 3093 PROST20024250 1124  38 . . . 445 3094 PROST20028970 1125  30 .. . 821 3095 PROST20033240 1126  39 . . . 1682 3096 PROST20035170 1127 689 . . . 1078 3097 PROST20035830 1128 1154 . . . 1468 3098PROST20036280 1129 1801 . . . 2295 3099 PROST20036350 1130  22 . . .2175 3100 PROST20039300 1131  87 . . . 635 3101 PROST20041460 1132 427 .. . 855 3102 PROST20042700 1133  461 . . . 1081 3103 PROST20045700 1134472 . . . 975 3104 PROST20047440 1135 1058 . . . 1441 3105 PROST200481701136  73 . . . 555 3106 PROST20050390 1137 1358 . . . 2035 3107PROST20051310 1138 1913 . . . 2737 3108 PROST20052720 1139 1195 . . .1515 3109 PROST20052850 1140  430 . . . 1185 3110 PROST20054660 1141  55. . . 753 3111 PROST20058860 1142 506 . . . 892 3112 PROST20060200 1143103 . . . 429 3113 PROST20062820 1144  415 . . . 1215 3114 PROST200634301145  126 . . . 1199 3115 PROST20065100 1146  95 . . . 1522 3116PROST20065790 1147  225 . . . 2555 3117 PROST20073280 1148  891 . . .1277 3118 PROST20075280 1149  97 . . . 885 3119 PROST20078710 1150  347. . . 1213 3120 PROST20082430 1151 2077 . . . 2436 3121 PROST200844701152  728 . . . 1498 3122 PROST20084680 1153 395 . . . 733 3123PROST20084720 1154 1528 . . . 1839 3124 PROST20087240 1155  766 . . .1452 3125 PROST20093470 1156 1288 . . . 1647 3126 PROST20094000 1157 376 . . . 1011 3127 PROST20097310 1158 1502 . . . 1903 3128PROST20097360 1159  99 . . . 602 3129 PROST20097840 1160  687 . . . 12893130 PROST20099090 1161  85 . . . 792 3131 PROST20102190 1162  86 . . .406 3132 PROST20102500 1163 1467 . . . 2051 3133 PROST20103820 1164 1770. . . 2078 3134 PROST20105450 1165 1027 . . . 1911 3135 PROST201060601166  97 . . . 705 3136 PROST20108850 1167 1173 . . . 1664 3137PROST20110120 1168  804 . . . 1139 3138 PROST20114100 1169  74 . . . 7723139 PROST20120070 1170  442 . . . 1593 3140 PROST20121570 1171  673 . .. 1185 3141 PROST20122490 1172  10 . . . 753 3142 PROST20124000 1173 943 . . . 1371 3143 PROST20125420 1174 1480 . . . 1968 3144PROST20127450 1175 255 . . . 857 3145 PROST20130320 1176  549 . . . 23093146 PROST20138730 1177 494 . . . 829 3147 PROST20146590 1178  618 . . .2351 3148 PROST20151370 1179  99 . . . 482 3149 PROST20152510 1180 1095. . . 2168 3150 PROST20152870 1181  258 . . . 1322 3151 PROST201553701182  606 . . . 2255 3152 PROST20156360 1183 1557 . . . 1898 3153PROST20159320 1184  67 . . . 567 3154 PROST20168600 1185  336 . . . 17003155 PUAEN10000650 1186 341 . . . 943 3156 PUAEN10000870 1187 1676 . . .2029 3157 PUAEN10001640 1188  332 . . . 1138 3158 PUAEN20000800 1189 327 . . . 1811 3159 PUAEN20001520 1190  155 . . . 1243 3160PUAEN20002470 1191   3 . . . 2417 3161 PUAEN20003120 1192  93 . . . 22163162 SALGL10001070 1193  89 . . . 997 3163 SKMUS20006790 1194  389 . . .1330 3164 SKMUS20007260 1195    47 . . . >1320 3165 SKMUS20008730 1196 91 . . . 1407 3166 SKMUS20017400 1197  84 . . . 815 3167 SKMUS200207701198 179 . . . 781 3168 SKMUS20026340 1199  57 . . . 1202 3169SKMUS20040440 1200  27 . . . 1091 3170 SKMUS20064810 1201  91 . . . 4593171 SKMUS20073150 1202    17 . . . >822 3172 SKMUS20073590 1203 438 . .. 824 3173 SKMUS20079150 1204  165 . . . 1235 3174 SKMUS20091900 1205 57 . . . 359 3175 SKNMC10001230 1206  87 . . . 1814 3176 SKNMC200063501207  326 . . . 1738 3177 SKNSH10001010 1208 1189 . . . 1530 3178SKNSH20007160 1209 113 . . . 562 3179 SKNSH20009710 1210  71 . . . 6223180 SKNSH20030640 1211 1635 . . . 2090 3181 SKNSH20040390 1212 246 . .. 911 3182 SKNSH20052400 1213  926 . . . 2017 3183 SKNSH20057920 1214 369 . . . 1352 3184 SKNSH20068220 1215  504 . . . 1235 3185SKNSH20094350 1216  70 . . . 591 3186 SMINT20000070 1217  752 . . . 18583187 SMINT20002320 1218  607 . . . 1761 3188 SMINT20006020 1219 1215 . .. 2348 3189 SMINT20006090 1220  75 . . . 602 3190 SMINT20007470 1221 154 . . . 1650 3191 SMINT20008110 1222  784 . . . 1557 3192SMINT20011830 1223  34 . . . 447 3193 SMINT20011950 1224  732 . . . 20063194 SMINT20012220 1225 239 . . . 616 3195 SMINT20013970 1226 1117 . . .1686 3196 SMINT20014610 1227 287 . . . 814 3197 SMINT20016150 1228  911. . . 1675 3198 SMINT20017310 1229 1220 . . . 1561 3199 SMINT200212601230 1066 . . . 1407 3200 SMINT20023110 1231 1696 . . . 2073 3201SMINT20024140 1232  31 . . . 555 3202 SMINT20026200 1233  323 . . . 21703203 SMINT20028800 1234  476 . . . 1696 3204 SMINT20028840 1235  89 . .. 823 3205 SMINT20030740 1236  172 . . . 1833 3206 SMINT20031280 1237 542 . . . 1489 3207 SMINT20035050 1238  227 . . . 2149 3208SMINT20035510 1239    168 . . . >1891 3209 SMINT20036440 1240  207 . . .2084 3210 SMINT20038660 1241  289 . . . 1449 3211 SMINT20039050 1242   175 . . . >2338 3212 SMINT20043390 1243 1465 . . . 2094 3213SMINT20044140 1244  30 . . . 1718 3214 SMINT20044730 1245  45 . . . 17873215 SMINT20045470 1246 1156 . . . 1539 3216 SMINT20045830 1247  287 . .. 1882 3217 SMINT20045890 1248  893 . . . 1372 3218 SMINT20047290 1249 2 . . . 637 3219 SMINT20048720 1250   1834 . . . >2374 3220SMINT20049920 1251 1384 . . . 1860 3221 SMINT20052130 1252 271 . . . 8913222 SMINT20054050 1253  361 . . . 1839 3223 SMINT20056230 1254  73 . .. 1674 3224 SMINT20056240 1255 1108 . . . 1533 3225 SMINT20062050 1256 75 . . . 1964 3226 SMINT20067080 1257  138 . . . 2075 3227SMINT20070620 1258  44 . . . 445 3228 SMINT20074330 1259  71 . . . 5323229 SMINT20077920 1260  843 . . . 1166 3230 SMINT20077960 1261 1010 . .. 2467 3231 SMINT20081330 1262 250 . . . 618 3232 SMINT20083290 1263  80. . . 1606 3233 SMINT20084910 1264 664 . . . 987 3234 SMINT20085310 1265129 . . . 500 3235 SMINT20085450 1266  66 . . . 437 3236 SMINT200862501267 1958 . . . 2287 3237 SMINT20086720 1268  233 . . . 1003 3238SMINT20088440 1269  31 . . . 438 3239 SMINT20088690 1270  26 . . . 5803240 SMINT20089210 1271 1259 . . . 1672 3241 SMINT20089600 1272  241 . .. 1335 3242 SMINT20091190 1273  290 . . . 1765 3243 SMINT20092120 1274 33 . . . 416 3244 SMINT20092160 1275 439 . . . 780 3245 SMINT200936301276 1822 . . . 2241 3246 SMINT20094150 1277 511 . . . 966 3247SMINT20094680 1278  36 . . . 452 3248 SPLEN20005160 1279 2342 . . . 26593249 SPLEN20005370 1280 1497 . . . 1856 3250 SPLEN20006950 1281  702 . .. 1343 3251 SPLEN20011350 1282 1127 . . . 1537 3252 SPLEN20012450 1283134 . . . 442 3253 SPLEN20015030 1284 376 . . . 945 3254 SPLEN200151001285 1367 . . . 2137 3255 SPLEN20016500 1286 328 . . . 816 3256SPLEN20017610 1287  940 . . . 1314 3257 SPLEN20017810 1288 101 . . . 5563258 SPLEN20019120 1289 176 . . . 487 3259 SPLEN20020530 1290 358 . . .762 3260 SPLEN20023430 1291 1067 . . . 1426 3261 SPLEN20023540 1292  644. . . 1903 3262 SPLEN20023850 1293    467 . . . >1879 3263 SPLEN200241901294  319 . . . 1368 3264 SPLEN20024510 1295 1070 . . . 1423 3265SPLEN20024620 1296   3 . . . 1514 3266 SPLEN20024770 1297  134 . . .2353 3267 SPLEN20024930 1298 1150 . . . 3069 3268 SPLEN20029170 1299  67. . . 750 3269 SPLEN20036780 1300 1432 . . . 1752 3270 SPLEN200391801301  359 . . . 1534 3271 SPLEN20040780 1302 1675 . . . 2346 3272SPLEN20041810 1303  801 . . . 1142 3273 SPLEN20042200 1304 1123 . . .1935 3274 SPLEN20043430 1305 224 . . . 565 3275 SPLEN20043460 1306  55 .. . 1899 3276 SPLEN20043680 1307 1337 . . . 2371 3277 SPLEN20045550 1308  5 . . . 1513 3278 SPLEN20048800 1309 2038 . . . 2352 3279SPLEN20049840 1310  82 . . . 3378 3280 SPLEN20050090 1311  418 . . .2202 3281 SPLEN20051420 1312  685 . . . 1983 3282 SPLEN20054160 1313 186 . . . 2069 3283 SPLEN20054500 1314  667 . . . 1443 3284SPLEN20055600 1315  146 . . . 1033 3285 SPLEN20057830 1316  507 . . .1163 3286 SPLEN20057900 1317 1883 . . . 2431 3287 SPLEN20058180 1318 803 . . . 1120 3288 SPLEN20059270 1319  162 . . . 1586 3289SPLEN20062830 1320 282 . . . 785 3290 SPLEN20063250 1321  315 . . . 15353291 SPLEN20063890 1322 133 . . . 996 3292 SPLEN20067010 1323   2702 . .. >3023 3293 SPLEN20071820 1324  876 . . . 1592 3294 SPLEN20073500 1325 174 . . . 2210 3295 SPLEN20073880 1326  220 . . . 2595 3296SPLEN20076190 1327  20 . . . 331 3297 SPLEN20076470 1328  575 . . . 17143298 SPLEN20080070 1329   5 . . . 1339 3299 SPLEN20081640 1330  946 . .. 1308 3300 SPLEN20085910 1331 1084 . . . 1434 3301 SPLEN20087370 13322670 . . . 3098 3302 SPLEN20087860 1333 255 . . . 755 3303 SPLEN200908801334 1742 . . . 2194 3304 SPLEN20098030 1335  268 . . . 1077 3305SPLEN20100040 1336 101 . . . 862 3306 SPLEN20101950 1337  122 . . . 11983307 SPLEN20104150 1338 1146 . . . 2219 3308 SPLEN20104690 1339 661 . .. 990 3309 SPLEN20105100 1340 1425 . . . 1859 3310 SPLEN20108000 1341 887 . . . 1351 3311 SPLEN20108460 1342 2254 . . . 2607 3312SPLEN20110180 1343  147 . . . 1292 3313 SPLEN20110210 1344 1831 . . .2271 3314 SPLEN20110860 1345 1489 . . . 1887 3315 SPLEN20111450 13462768 . . . 3208 3316 SPLEN20114190 1347  154 . . . 1440 3317SPLEN20116720 1348   9 . . . 1583 3318 SPLEN20117580 1349  218 . . .1240 3319 SPLEN20118050 1350  145 . . . 1122 3320 SPLEN20121790 1351 569 . . . 1054 3321 SPLEN20125230 1352  971 . . . 1324 3322SPLEN20126110 1353 254 . . . 991 3323 SPLEN20135030 1354  40 . . . 18483324 SPLEN20136700 1355 1296 . . . 1628 3325 SPLEN20136730 1356 1312 . .. 1644 3326 SPLEN20137530 1357 2676 . . . 3221 3327 SPLEN20138600 13581166 . . . 1582 3328 SPLEN20139100 1359  63 . . . 1532 3329SPLEN20139360 1360  763 . . . 1827 3330 SPLEN20175920 1361 1123 . . .1590 3331 SPLEN20176130 1362  16 . . . 549 3332 SPLEN20177400 1363 1078. . . 1431 3333 SPLEN20180980 1364 410 . . . 823 3334 SPLEN20181570 1365   214 . . . >2609 3335 SPLEN20182850 1366 168 . . . 659 3336SPLEN20182990 1367  55 . . . 1881 3337 SPLEN20183020 1368 265 . . . 7233338 SPLEN20183950 1369 402 . . . 746 3339 SPLEN20187490 1370    98 . .. >2458 3340 SPLEN20190080 1371  914 . . . 1342 3341 SPLEN20190430 1372   884 . . . >1942 3342 SPLEN20190770 1373  97 . . . 771 3343SPLEN20191020 1374  140 . . . 1426 3344 SPLEN20192570 1375 325 . . . 6543345 SPLEN20193230 1376 253 . . . 588 3346 SPLEN20193490 1377 321 . . .854 3347 SPLEN20193750 1378  845 . . . 1306 3348 SPLEN20193790 1379  290. . . 2278 3349 SPLEN20195710 1380  64 . . . 516 3350 SPLEN20197090 1381 11 . . . 550 3351 SPLEN20197740 1382  2 . . . 499 3352 SPLEN201979301383    803 . . . >1625 3353 SPLEN20198390 1384  14 . . . 1873 3354SPLEN20199850 1385  575 . . . 1009 3355 SPLEN20200070 1386 353 . . . 6553356 SPLEN20200340 1387 1047 . . . 1814 3357 SPLEN20201830 1388  143 . .. 1177 3358 SPLEN20203590 1389 160 . . . 471 3359 SPLEN20204670 1390  6. . . 311 3360 SPLEN20205120 1391  682 . . . 1542 3361 TESOP100003501392 1646 . . . 2101 3362 TESOP10001600 1393  282 . . . 1352 3363TESTI10000190 1394  84 . . . 2042 3364 TESTI10000850 1395  925 . . .1311 3365 TESTI10001570 1396  141 . . . 1919 3366 TESTI20004310 1397  55. . . 2484 3367 TESTI20005980 1398   1350 . . . >1866 3368 TESTI200061601399  53 . . . 1720 3369 TESTI20006830 1400  313 . . . 1719 3370TESTI20012080 1401  89 . . . 1867 3371 TESTI20012360 1402 178 . . . 5943372 TESTI20016970 1403  133 . . . 1842 3373 TESTI20019590 1404 210 . .. 752 3374 TESTI20028020 1405  201 . . . 1298 3375 TESTI20029100 14061743 . . . 2147 3376 TESTI20030200 1407  94 . . . 2091 3377TESTI20030440 1408  60 . . . 1931 3378 TESTI20030610 1409  547 . . .1371 3379 TESTI20031310 1410  889 . . . 2235 3380 TESTI20031410 1411 201 . . . 1655 3381 TESTI20032770 1412  163 . . . 1002 3382TESTI20034750 1413 472 . . . 804 3383 TESTI20035330 1414  13 . . . 5583384 TESTI20035790 1415  16 . . . 2163 3385 TESTI20038240 1416  163 . .. 2502 3386 TESTI20040850 1417  52 . . . 669 3387 TESTI20041630 1418 330 . . . 1526 3388 TESTI20043130 1419 410 . . . 715 3389 TESTI200431801420  68 . . . 2515 3390 TESTI20043220 1421 1496 . . . 1957 3391TESTI20043910 1422  37 . . . 1728 3392 TESTI20043990 1423  311 . . .1153 3393 TESTI20044900 1424  234 . . . 1595 3394 TESTI20045390 1425 156 . . . 2108 3395 TESTI20045740 1426 199 . . . 549 3396 TESTI200461101427  24 . . . 1826 3397 TESTI20046490 1428  554 . . . 2542 3398TESTI20046540 1429  123 . . . 2309 3399 TESTI20046870 1430  278 . . .1645 3400 TESTI20046890 1431  276 . . . 2702 3401 TESTI20047370 1432   2. . . 2134 3402 TESTI20047930 1433  239 . . . 1843 3403 TESTI200490601434 1191 . . . 1784 3404 TESTI20049410 1435  281 . . . 2170 3405TESTI20049990 1436 355 . . . 915 3406 TESTI20050170 1437 314 . . . 8083407 TESTI20050400 1438 111 . . . 440 3408 TESTI20050720 1439  68 . . .1621 3409 TESTI20051200 1440 1561 . . . 2145 3410 TESTI20051730 1441 183 . . . 1943 3411 TESTI20052670 1442  759 . . . 1910 3412TESTI20053070 1443  98 . . . 1285 3413 TESTI20053260 1444 456 . . . 8423414 TESTI20053780 1445  176 . . . 1948 3415 TESTI20053800 1446  42 . .. 1694 3416 TESTI20053950 1447    528 . . . >1782 3417 TESTI200547001448  19 . . . 1956 3418 TESTI20055680 1449  53 . . . 1510 3419TESTI20055880 1450  127 . . . 1644 3420 TESTI20056030 1451  543 . . .1658 3421 TESTI20057200 1452 279 . . . 611 3422 TESTI20057430 1453  131. . . 1858 3423 TESTI20057590 1454  37 . . . 1062 3424 TESTI200578401455  180 . . . 1271 3425 TESTI20057880 1456  39 . . . 1697 3426TESTI20058350 1457  25 . . . 1368 3427 TESTI20058920 1458  108 . . .1088 3428 TESTI20059080 1459 2134 . . . 3069 3429 TESTI20059330 1460 540. . . 845 3430 TESTI20059370 1461  655 . . . 1137 3431 TESTI200594801462  52 . . . 1362 3432 TESTI20059790 1463  203 . . . 1336 3433TESTI20059810 1464    324 . . . >1914 3434 TESTI20060080 1465 172 . . .858 3435 TESTI20060150 1466  383 . . . 1663 3436 TESTI20060350 1467  81. . . 1427 3437 TESTI20060450 1468 1306 . . . 1752 3438 TESTI200608301469  54 . . . 2543 3439 TESTI20061090 1470 382 . . . 798 3440TESTI20061200 1471  382 . . . 1938 3441 TESTI20062120 1472  37 . . .1632 3442 TESTI20062180 1473  169 . . . 1413 3443 TESTI20062580 1474 863 . . . 1165 3444 TESTI20063330 1475 1334 . . . 1678 3445TESTI20063410 1476 2175 . . . 2501 3446 TESTI20063600 1477 1399 . . .1809 3447 TESTI20064370 1478  201 . . . 1706 3448 TESTI20064530 1479  68. . . 2737 3449 TESTI20064650 1480  353 . . . 2542 3450 TESTI200649901481  733 . . . 1290 3451 TESTI20065650 1482  374 . . . 1609 3452TESTI20066150 1483  98 . . . 2473 3453 TESTI20066170 1484  143 . . .1309 3454 TESTI20066280 1485 100 . . . 879 3455 TESTI20066330 1486  26 .. . 1528 3456 TESTI20066590 1487 306 . . . 740 3457 TESTI20066650 1488 415 . . . 1362 3458 TESTI20067350 1489  342 . . . 1073 3459TESTI20067440 1490  196 . . . 1887 3460 TESTI20067480 1491  127 . . .1758 3461 TESTI20068530 1492  791 . . . 1369 3462 TESTI20068790 1493  1033 . . . >1738 3463 TESTI20068940 1494    55 . . . >1867 3464TESTI20070400 1495  147 . . . 2300 3465 TESTI20070740 1496  743 . . .1480 3466 TESTI20071130 1497  224 . . . 1738 3467 TESTI20071630 1498  38. . . 727 3468 TESTI20073460 1499  97 . . . 1584 3469 TESTI20075240 1500 259 . . . 1686 3470 TESTI20076570 1501  622 . . . 1110 3471TESTI20076920 1502  90 . . . 608 3472 TESTI20079060 1503  105 . . . 20963473 TESTI20079220 1504  54 . . . 2252 3474 TESTI20079980 1505  62 . . .1300 3475 TESTI20080460 1506 1458 . . . 1787 3476 TESTI20081890 1507 184 . . . 2520 3477 TESTI20083890 1508 1102 . . . 1596 3478TESTI20084250 1509  386 . . . 2035 3479 TESTI20085670 1510 1459 . . .2001 3480 TESTI20086840 1511  10 . . . 1488 3481 TESTI20088840 1512  172. . . 1587 3482 TESTI20089290 1513  26 . . . 421 3483 TESTI20090180 1514 527 . . . 1657 3484 TESTI20090970 1515  548 . . . 2308 3485TESTI20091360 1516  745 . . . 1230 3486 TESTI20092170 1517  882 . . .1256 3487 TESTI20093900 1518  265 . . . 1791 3488 TESTI20094620 15191897 . . . 2319 3489 TESTI20095200 1520  94 . . . 1149 3490TESTI20095440 1521 1134 . . . 1496 3491 TESTI20095770 1522    278 . .. >2225 3492 TESTI20095880 1523  144 . . . 1775 3493 TESTI20097270 1524157 . . . 693 3494 TESTI20099350 1525    123 . . . >1773 3495TESTI20100090 1526 1020 . . . 2057 3496 TESTI20102390 1527 1873 . . .2247 3497 TESTI20103690 1528  71 . . . 1048 3498 TESTI20104090 1529  364. . . 1716 3499 TESTI20105130 1530  320 . . . 1966 3500 TESTI201059101531  151 . . . 2265 3501 TESTI20106170 1532  235 . . . 1338 3502TESTI20106820 1533 1191 . . . 1604 3503 TESTI20107240 1534  163 . . .2844 3504 TESTI20107320 1535 377 . . . 787 3505 TESTI20107340 1536 1229. . . 1723 3506 TESTI20108060 1537 371 . . . 925 3507 TESTI20112540 1538 148 . . . 1554 3508 TESTI20112860 1539  285 . . . 1829 3509TESTI20113150 1540  374 . . . 1042 3510 TESTI20113940 1541 1185 . . .1598 3511 TESTI20114480 1542  161 . . . 2032 3512 TESTI20116050 1543 218 . . . 1756 3513 TESTI20116120 1544  17 . . . 1276 3514TESTI20117500 1545 140 . . . 508 3515 TESTI20118460 1546  69 . . . 15803516 TESTI20120500 1547 135 . . . 926 3517 TESTI20120900 1548  60 . . .665 3518 TESTI20121040 1549   8 . . . 1525 3519 TESTI20121710 1550  278. . . 1543 3520 TESTI20122070 1551  145 . . . 1359 3521 TESTI201224401552  25 . . . 465 3522 TESTI20124440 1553 469 . . . 801 3523TESTI20125280 1554  371 . . . 1363 3524 TESTI20125440 1555 342 . . . 6713525 TESTI20125920 1556  31 . . . 1680 3526 TESTI20126280 1557  169 . .. 2562 3527 TESTI20130530 1558  298 . . . 1692 3528 TESTI20131440 1559 223 . . . 1278 3529 TESTI20132310 1560 204 . . . 713 3530 TESTI201326801561 1011 . . . 1448 3531 TESTI20134010 1562  334 . . . 1464 3532TESTI20134270 1563  59 . . . 601 3533 TESTI20134680 1564  324 . . . 27263534 TESTI20134970 1565  197 . . . 1873 3535 TESTI20136010 1566    152 .. . >1415 3536 TESTI20140970 1567 376 . . . 801 3537 TESTI20142480 15681466 . . . 1939 3538 TESTI20142540 1569 1231 . . . 1593 3539TESTI20143180 1570  201 . . . 1946 3540 TESTI20144390 1571  776 . . .1552 3541 TESTI20145780 1572 1315 . . . 1746 3542 TESTI20148380 1573  32. . . 2680 3543 TESTI20149880 1574 581 . . . 982 3544 TESTI20150420 1575 221 . . . 1162 3545 TESTI20150920 1576  142 . . . 1713 3546TESTI20151050 1577 1290 . . . 1736 3547 TESTI20151800 1578  671 . . .1099 3548 TESTI20152490 1579  717 . . . 1226 3549 TESTI20153310 1580 151 . . . 1317 3550 TESTI20154370 1581  192 . . . 1544 3551TESTI20159380 1582  852 . . . 1679 3552 TESTI20161010 1583  33 . . . 5393553 TESTI20162780 1584  607 . . . 1299 3554 TESTI20162980 1585  224 . .. 1414 3555 TESTI20164210 1586  526 . . . 1593 3556 TESTI20165680 1587154 . . . 552 3557 TESTI20165990 1588 201 . . . 992 3558 TESTI201662901589  351 . . . 2786 3559 TESTI20166670 1590  754 . . . 1938 3560TESTI20167580 1591   1152 . . . >1543 3561 TESTI20168880 1592 201 . . .524 3562 TESTI20169500 1593  280 . . . 1674 3563 TESTI20170170 1594  199. . . 1530 3564 TESTI20170280 1595  1 . . . 696 3565 TESTI20170690 1596 61 . . . 474 3566 TESTI20170890 1597  882 . . . 1238 3567 TESTI201710701598 1088 . . . 1501 3568 TESTI20173050 1599  724 . . . 1218 3569TESTI20173110 1600 1194 . . . 1586 3570 TESTI20173960 1601  376 . . .1764 3571 TESTI20175370 1602  828 . . . 1724 3572 TESTI20176450 1603  1. . . 996 3573 TESTI20179230 1604  162 . . . 1709 3574 TESTI201795101605   1702 . . . >2042 3575 TESTI20180600 1606 162 . . . 857 3576TESTI20182210 1607  736 . . . 1182 3577 TESTI20182760 1608  266 . . .1390 3578 TESTI20183680 1609    778 . . . >1927 3579 TESTI20184280 1610   35 . . . >1732 3580 TESTI20184750 1611  899 . . . 2116 3581TESTI20184760 1612  161 . . . 1741 3582 TESTI20184820 1613 189 . . . 7223583 TESTI20186110 1614  221 . . . 1606 3584 TESTI20192570 1615 109 . .. 687 3585 TESTI20193080 1616  149 . . . 2194 3586 TESTI20193520 1617 311 . . . 1375 3587 TESTI20194880 1618  616 . . . 1554 3588TESTI20196690 1619 271 . . . 945 3589 TESTI20196970 1620  789 . . . 15653590 TESTI20197030 1621  263 . . . 1717 3591 TESTI20197290 1622  643 . .. 1314 3592 TESTI20197600 1623 100 . . . 909 3593 TESTI20198540 1624  21. . . 1553 3594 TESTI20198600 1625  909 . . . 1328 3595 TESTI201991101626  622 . . . 1617 3596 TESTI20199980 1627  764 . . . 1102 3597TESTI20200120 1628 661 . . . 966 3598 TESTI20200840 1629 378 . . . 8183599 TESTI20201760 1630  22 . . . 603 3600 TESTI20202830 1631 631 . . .972 3601 TESTI20204260 1632  714 . . . 1406 3602 TESTI20205100 1633  270. . . 1763 3603 TESTI20205150 1634 1286 . . . 1663 3604 TESTI202052501635  32 . . . 1888 3605 TESTI20207170 1636  1 . . . 795 3606TESTI20209050 1637  269 . . . 1900 3607 TESTI20210030 1638 328 . . . 6753608 TESTI20210570 1639  280 . . . 1362 3609 TESTI20211380 1640 372 . .. 848 3610 TESTI20212970 1641  93 . . . 2102 3611 TESTI20214630 1642 690 . . . 1106 3612 TESTI20215310 1643 294 . . . 899 3613 TESTI202191101644  982 . . . 1344 3614 TESTI20219390 1645 253 . . . 573 3615TESTI20220230 1646 116 . . . 967 3616 TESTI20221790 1647  109 . . . 18303617 TESTI20222030 1648  277 . . . 2277 3618 TESTI20222460 1649  162 . .. 1889 3619 TESTI20223380 1650 322 . . . 831 3620 TESTI20226520 1651 178 . . . 1392 3621 TESTI20227380 1652  20 . . . 1747 3622TESTI20228120 1653  31 . . . 858 3623 TESTI20228740 1654  607 . . . 10263624 TESTI20244220 1655  757 . . . 2448 3625 TESTI20244430 1656  17 . .. 1444 3626 TESTI20244460 1657  684 . . . 1511 3627 TESTI20244730 1658 127 . . . 1044 3628 TESTI20245600 1659  255 . . . 1523 3629TESTI20245860 1660  684 . . . 1058 3630 TESTI20246410 1661 1513 . . .1818 3631 TESTI20246480 1662  380 . . . 1399 3632 TESTI20247440 1663 425. . . 907 3633 TESTI20248850 1664   3 . . . 1829 3634 TESTI20249360 1665 600 . . . 1565 3635 TESTI20250220 1666  63 . . . 2015 3636TESTI20250630 1667  482 . . . 1690 3637 TESTI20251440 1668  42 . . .1271 3638 TESTI20251610 1669  430 . . . 1218 3639 TESTI20251740 1670 730 . . . 1104 3640 TESTI20252690 1671 1182 . . . 2138 3641TESTI20254030 1672  363 . . . 1958 3642 TESTI20254090 1673  878 . . .1360 3643 TESTI20254480 1674  320 . . . 1390 3644 TESTI20254990 1675 693 . . . 1799 3645 TESTI20255460 1676  152 . . . 2710 3646TESTI20256560 1677    169 . . . >2257 3647 TESTI20257910 1678  457 . . .1311 3648 TESTI20258720 1679  38 . . . 1630 3649 TESTI20259110 1680  486. . . 1805 3650 TESTI20259200 1681  227 . . . 1369 3651 TESTI202601401682 1113 . . . 1421 3652 TESTI20260640 1683   6 . . . 1109 3653TESTI20261040 1684  14 . . . 970 3654 TESTI20261160 1685 257 . . . 8683655 TESTI20261680 1686 1422 . . . 1901 3656 TESTI20262150 1687  315 . .. 2765 3657 TESTI20262940 1688  255 . . . 1574 3658 TESTI20264530 1689 150 . . . 1580 3659 TESTI20264910 1690 1638 . . . 2378 3660TESTI20265150 1691 1023 . . . 1409 3661 TESTI20265340 1692  965 . . .1552 3662 TESTI20265890 1693  994 . . . 1308 3663 TESTI20266050 1694 116 . . . 1522 3664 TESTI20268240 1695  70 . . . 1638 3665TESTI20269250 1696    17 . . . >1926 3666 TESTI20269360 1697  682 . . .1005 3667 TESTI20270130 1698  99 . . . 512 3668 TESTI20271790 1699  101. . . 1822 3669 TESTI20272380 1700 121 . . . 492 3670 TESTI20274960 1701 619 . . . 1716 3671 TESTI20277300 1702  263 . . . 1600 3672TESTI20278280 1703  80 . . . 607 3673 TESTI20282420 1704  52 . . . 5283674 TESTI20282530 1705  699 . . . 1985 3675 TESTI20282900 1706  30 . .. 341 3676 TESTI20284260 1707  29 . . . 493 3677 TESTI20285230 1708 1710. . . 2366 3678 TESTI20286590 1709  519 . . . 1121 3679 TESTI202877601710  775 . . . 2634 3680 THYMU10004280 1711 617 . . . 988 3681THYMU20006020 1712  608 . . . 1387 3682 THYMU20007020 1713 1755 . . .2111 3683 THYMU20007750 1714 1077 . . . 1499 3684 THYMU20008000 17151506 . . . 1955 3685 THYMU20009460 1716 1334 . . . 1723 3686THYMU20009500 1717  717 . . . 2117 3687 THYMU20009710 1718 247 . . . 7623688 THYMU20010180 1719 191 . . . 634 3689 THYMU20010710 1720  850 . . .1164 3690 THYMU20012020 1721 1160 . . . 1561 3691 THYMU20012560 1722  47. . . 517 3692 THYMU20013250 1723  131 . . . 1309 3693 THYMU200138101724 196 . . . 927 3694 THYMU20014430 1725 1280 . . . 1678 3695THYMU20017270 1726  16 . . . 660 3696 THYMU20018250 1727 1205 . . . 21223697 THYMU20018390 1728  237 . . . 1373 3698 THYMU20019000 1729 405 . .. 758 3699 THYMU20019260 1730 317 . . . 736 3700 THYMU20020370 1731 1332. . . 1733 3701 THYMU20020800 1732  600 . . . 1196 3702 THYMU200210901733  211 . . . 1281 3703 THYMU20021540 1734  100 . . . 1578 3704THYMU20023560 1735 1429 . . . 1884 3705 THYMU20024500 1736  199 . . .1584 3706 THYMU20025480 1737 1362 . . . 1751 3707 THYMU20026950 1738  9. . . 920 3708 THYMU20028150 1739  233 . . . 1222 3709 THYMU200284101740  10 . . . 1086 3710 THYMU20029830 1741  46 . . . 456 3711THYMU20030460 1742  453 . . . 1175 3712 THYMU20030690 1743 1658 . . .2269 3713 THYMU20031330 1744  90 . . . 569 3714 THYMU20032820 1745  250. . . 1176 3715 THYMU20034400 1746  791 . . . 1123 3716 THYMU200347901747 120 . . . 452 3717 THYMU20036500 1748  56 . . . 1657 3718THYMU20039320 1749  584 . . . 1339 3719 THYMU20043440 1750 1301 . . .1615 3720 THYMU20043560 1751 292 . . . 621 3721 THYMU20044100 1752 1800. . . 2228 3722 THYMU20044520 1753 1387 . . . 1899 3723 THYMU200463501754 1863 . . . 2351 3724 THYMU20046770 1755 321 . . . 671 3725THYMU20049060 1756 172 . . . 732 3726 THYMU20050010 1757  206 . . . 16813727 THYMU20051340 1758  886 . . . 1209 3728 THYMU20052460 1759 1300 . .. 1683 3729 THYMU20052830 1760  92 . . . 1504 3730 THYMU20054800 1761479 . . . 880 3731 THYMU20055450 1762 112 . . . 426 3732 THYMU200554601763  20 . . . 361 3733 THYMU20055740 1764  901 . . . 1341 3734THYMU20055760 1765 232 . . . 738 3735 THYMU20058550 1766 1170 . . . 14933736 THYMU20060480 1767   2046 . . . >2453 3737 THYMU20062520 1768 299 .. . 655 3738 THYMU20062610 1769  136 . . . 1953 3739 THYMU20062770 1770 381 . . . 1199 3740 THYMU20063650 1771 264 . . . 800 3741 THYMU200646801772 253 . . . 621 3742 THYMU20066660 1773  405 . . . 1487 3743THYMU20069130 1774 341 . . . 961 3744 THYMU20069460 1775 231 . . . 5753745 THYMU20069650 1776  728 . . . 1036 3746 THYMU20070250 1777  81 . .. 1703 3747 THYMU20071120 1778  170 . . . 1792 3748 THYMU20071460 1779152 . . . 499 3749 THYMU20072580 1780 1981 . . . 2286 3750 THYMU200730701781  551 . . . 1225 3751 THYMU20073080 1782  755 . . . 1198 3752THYMU20077250 1783  645 . . . 1241 3753 THYMU20078020 1784 1290 . . .1598 3754 THYMU20078240 1785 1506 . . . 1838 3755 THYMU20079690 17861049 . . . 1714 3756 THYMU20080490 1787  57 . . . 398 3757 THYMU200811101788  629 . . . 1246 3758 THYMU20083390 1789 592 . . . 924 3759THYMU20083500 1790  744 . . . 1067 3760 THYMU20083830 1791  155 . . .1786 3761 THYMU20084520 1792 286 . . . 597 3762 THYMU20086430 1793  769. . . 1077 3763 THYMU20087270 1794  842 . . . 2008 3764 THYMU200891701795 305 . . . 619 3765 THYMU20089900 1796 1008 . . . 1421 3766THYMU20090230 1797 106 . . . 594 3767 THYMU20091040 1798  728 . . . 10543768 THYMU20095920 1799 1809 . . . 2378 3769 THYMU20096580 1800 120 . .. 692 3770 THYMU20097920 1801  95 . . . 2086 3771 THYMU20098350 1802  99. . . 1802 3772 THYMU20099060 1803  80 . . . 1573 3773 THYMU201009401804   8 . . . 2218 3774 THYMU20104480 1805  39 . . . 1451 3775THYMU20106990 1806  673 . . . 1464 3776 THYMU20110720 1807  372 . . .1070 3777 THYMU20112570 1808 117 . . . 455 3778 THYMU20112590 1809  112. . . 1827 3779 THYMU20115380 1810 1507 . . . 1839 3780 THYMU201157301811  943 . . . 1632 3781 THYMU20117850 1812 1625 . . . 1948 3782THYMU20120240 1813 1239 . . . 3002 3783 THYMU20120730 1814 1257 . . .2459 3784 THYMU20121040 1815  230 . . . 2323 3785 THYMU20128910 1816 181 . . . 1185 3786 THYMU20129020 1817   1545 . . . >2019 3787THYMU20130470 1818  87 . . . 1169 3788 THYMU20134260 1819 1845 . . .2171 3789 THYMU20137050 1820  958 . . . 1341 3790 THYMU20137570 18212113 . . . 2571 3791 THYMU20139160 1822  69 . . . 686 3792 THYMU201405101823 1312 . . . 1626 3793 THYMU20143230 1824  575 . . . 2023 3794THYMU20145990 1825 1330 . . . 2262 3795 THYMU20148010 1826 326 . . . 8203796 THYMU20149230 1827 581 . . . 925 3797 THYMU20150190 1828 1516 . . .1908 3798 THYMU20151610 1829  218 . . . 1663 3799 THYMU20153210 18301135 . . . 2340 3800 THYMU20154790 1831 1220 . . . 1753 3801THYMU20157620 1832  771 . . . 1487 3802 THYMU20163600 1833 1216 . . .1650 3803 THYMU20170080 1834  944 . . . 1399 3804 THYMU20170230 1835 835 . . . 1941 3805 THYMU20171580 1836  821 . . . 1150 3806THYMU20174490 1837  52 . . . 453 3807 THYMU20174790 1838  29 . . . 3703808 THYMU20175260 1839  991 . . . 1452 3809 THYMU20176010 1840  12 . .. 2039 3810 THYMU20177070 1841 1059 . . . 1415 3811 THYMU20178440 1842 81 . . . 1517 3812 THYMU20181890 1843  102 . . . 1652 3813THYMU20184550 1844  171 . . . 1886 3814 THYMU20185470 1845 161 . . . 8173815 THYMU20185650 1846  36 . . . 536 3816 THYMU20187210 1847 190 . . .507 3817 THYMU20191970 1848  230 . . . 1597 3818 TKIDN10000620 1849 1075. . . 1419 3819 TKIDN10001710 1850 1685 . . . 2365 3820 TKIDN100019201851  98 . . . 793 3821 TRACH20011010 1852  228 . . . 2033 3822TRACH20011540 1853 125 . . . 478 3823 TRACH20012490 1854  83 . . . 16003824 TRACH20021000 1855 234 . . . 854 3825 TRACH20021380 1856  313 . . .1890 3826 TRACH20025370 1857  947 . . . 1456 3827 TRACH20026640 1858 964 . . . 1557 3828 TRACH20029880 1859  201 . . . 1607 3829TRACH20040390 1860  125 . . . 3319 3830 TRACH20041090 1861 1254 . . .1589 3831 TRACH20043360 1862  30 . . . 2066 3832 TRACH20044990 1863 209. . . 790 3833 TRACH20049500 1864  840 . . . 1166 3834 TRACH200515901865  927 . . . 1247 3835 TRACH20057200 1866 2082 . . . 2393 3836TRACH20058000 1867  187 . . . 1647 3837 TRACH20073990 1868  98 . . . 4543838 TRACH20080810 1869   2073 . . . >2910 3839 TRACH20081270 1870  1681 . . . >2025 3840 TRACH20090060 1871  309 . . . 1781 3841TRACH20091070 1872  129 . . . 1841 3842 TRACH20093400 1873  131 . . .2251 3843 TRACH20093480 1874  694 . . . 1092 3844 TRACH20098510 1875 142 . . . 1944 3845 TRACH20101590 1876 1660 . . . 2220 3846TRACH20104510 1877  144 . . . 1184 3847 TRACH20108240 1878  36 . . . 7913848 TRACH20113020 1879  177 . . . 1352 3849 TRACH20122980 1880  732 . .. 1562 3850 TRACH20123870 1881 235 . . . 540 3851 TRACH20124970 1882 109. . . 486 3852 TRACH20125620 1883  22 . . . 387 3853 TRACH20129180 18841545 . . . 1898 3854 TRACH20131230 1885  123 . . . 2939 3855TRACH20139280 1886  152 . . . 1474 3856 TRACH20140180 1887 203 . . . 5533857 TRACH20143710 1888 1219 . . . 1998 3858 TRACH20149500 1889 163 . .. 906 3859 TRACH20149720 1890  187 . . . 1695 3860 TRACH20149740 1891 864 . . . 1505 3861 TRACH20158240 1892 254 . . . 796 3862 TRACH201593901893 1618 . . . 1941 3863 TRACH20160800 1894 1223 . . . 1531 3864TRACH20163470 1895  971 . . . 2356 3865 TRACH20164100 1896 372 . . . 7223866 TRACH20164810 1897 1685 . . . 2104 3867 TRACH20165330 1898  704 . .. 1102 3868 TRACH20165540 1899  810 . . . 1514 3869 TRACH20167090 1900 57 . . . 1148 3870 TRACH20170860 1901  186 . . . 1625 3871TRACH20173680 1902  83 . . . 1597 3872 TRACH20174980 1903  93 . . . 10883873 TRACH20182780 1904 1669 . . . 2070 3874 TRACH20185120 1905  13 . .. 339 3875 TRACH20188350 1906  248 . . . 1015 3876 TRACH20190460 1907 351 . . . 1526 3877 UMVEN10001380 1908 2122 . . . 2436 3878UTERU10001060 1909 187 . . . 552 3879 UTERU10001870 1910 1681 . . . 20313880 UTERU20000230 1911 120 . . . 608 3881 UTERU20000950 1912  240 . . .1658 3882 UTERU20011760 1913 1719 . . . 2090 3883 UTERU20013890 19141544 . . . 1951 3884 UTERU20016580 1915  25 . . . 1287 3885UTERU20026620 1916 1020 . . . 1556 3886 UTERU20027360 1917 1624 . . .1992 3887 UTERU20029930 1918  82 . . . 1902 3888 UTERU20031350 1919  35. . . 520 3889 UTERU20035770 1920  920 . . . 1282 3890 UTERU200401501921  917 . . . 1717 3891 UTERU20040370 1922  22 . . . 1866 3892UTERU20040390 1923  727 . . . 1200 3893 UTERU20040730 1924   1009 . .. >2303 3894 UTERU20041630 1925  105 . . . 1328 3895 UTERU20041970 1926 26 . . . 484 3896 UTERU20045200 1927  6 . . . 917 3897 UTERU200517901928  415 . . . 1341 3898 UTERU20064120 1929  147 . . . 1061 3899UTERU20065470 1930 389 . . . 694 3900 UTERU20079240 1931 408 . . . 7133901 UTERU20083020 1932  23 . . . 826 3902 UTERU20086530 1933 1274 . . .1783 3903 UTERU20087070 1934 1274 . . . 2467 3904 UTERU20087850 1935 464. . . 991 3905 UTERU20089300 1936  906 . . . 1253 3906 UTERU200893901937  11 . . . 1729 3907 UTERU20089620 1938 132 . . . 725 3908UTERU20090940 1939 122 . . . 631 3909 UTERU20091470 1940 260 . . . 6973910 UTERU20094830 1941  127 . . . 1578 3911 UTERU20095100 1942 1593 . .. 1913 3912 UTERU20099040 1943  59 . . . 883 3913 UTERU20099510 1944 705 . . . 2375 3914 UTERU20101150 1945  874 . . . 1188 3915UTERU20102260 1946 270 . . . 671 3916 UTERU20103040 1947 1164 . . . 17723917 UTERU20103200 1948 374 . . . 709 3918 UTERU20104310 1949  90 . . .425 3919 UTERU20106510 1950 1649 . . . 2275 3920 UTERU20121140 1951  880. . . 1644 3921 UTERU20122520 1952    572 . . . >2146 3922 UTERU201258101953  21 . . . 329 3923 UTERU20127030 1954  618 . . . 1763 3924UTERU20127150 1955  707 . . . 1699 3925 UTERU20128560 1956 203 . . . 7213926 UTERU20132620 1957  330 . . . 1007 3927 UTERU20134830 1958  121 . .. 1341 3928 UTERU20139760 1959  982 . . . 1659 3929 UTERU20140010 1960 42 . . . 368 3930 UTERU20167570 1961  57 . . . 710 3931 UTERU201689601962  317 . . . 1468 3932 UTERU20169020 1963  30 . . . 782 3933UTERU20173030 1964   1985 . . . >2355 3934 UTERU20176230 1965 1004 . . .1372 3935 UTERU20177150 1966  3 . . . 350 3936 UTERU20181270 1967 153 .. . 620 3937 UTERU20185220 1968  521 . . . 1357 3938 UTERU20188670 1969 231 . . . 1886 3939 UTERU20188840 1970 1834 . . . 2181 3940

Namely, primers used to synthesize polynucleotides can be designed basedon the nucleotide sequences of polynucleotides of the present inventionshown in SEQ ID NOs in the above Table 1. When one intends to synthesizefull-length cDNAs, an oligo dT primer can be used as the 3′-end primer.The length of the primers is usually 15-100 bp, and favorably between15-35 bp. In case of LA PCR, which is described below, the primer lengthof 25-35 bp may provide a good result.

A method to design a primer that enables a specific amplification basedon the aimed nucleotide sequence is known to those skilled in the art(Current Protocols in Molecular Biology, Ausubel et al. edit, (1987)John Wiley & Sons, Section 6.1-6.4). In designing a primer based on the5′-end sequence, the primer is designed so as that, in principle, theamplification products will include the translation start site.Accordingly, for example, when the 5′-end primer is designed based onthe nucleotide sequence of 5′ untranslated region (5′UTR), any part ofthe 5′-end, which ensures the specificity to the cDNA of interest, canbe selected as the primer.

When synthesizing a full-length cDNA, the target nucleotide sequence tobe amplified can extend to several thousand bp in some cDNA. However, itis possible to amplify such a long nucleotides by using such as LA PCR(Long and Accurate PCR). It is advantageous to use LA PCR whensynthesizing long DNA. In LA PCR, in which a special DNA polymerasehaving 3′->5′ exonuclease activity is used, misincorporated nucleotidescan be removed. Accordingly, accurate synthesis of the complementarystrand can be achieved even with a long nucleotide sequence. By using LAPCR, it is reported that amplification of a nucleotide with 20 kb longercan be achieved under desirable conditions (Takeshi Hayashi (1996)Jikken-Igaku Bessatsu, “Advanced Technologies in PCR” Youdo-sha).

A template DNA for synthesizing the full-length cDNA of the presentinvention can be obtained by using cDNA libraries that are prepared byvarious methods. The full-length cDNA clones of the present inventionare clones with high probability of completeness in length, which wereobtained by the method comprising the steps of [1] preparing librariescontaining cDNAs with the very high fullness ratio by oligo-capping, and[2] assembling the 5′-end sequences and selecting one with the highestprobability of completeness in length in the cluster formed (there aremany clones longer in the 5′-end direction).

However, the uses of primers designed based on the full-lengthnucleotide sequences provided by the present invention enable easilyobtaining full-length cDNAs without such a special technique.

The problem with the cDNA libraries prepared by the known methods orcommercially available is that mRNA contained in the libraries has verylow fullness ratio. Thus, it is difficult to screen full-length cDNAclone directly from the library using ordinary cloning methods. Thepresent invention has revealed a nucleotide sequence of novelfull-length cDNA. If a full-length nucleotide sequence is provided, itis possible to synthesize a target full-length cDNA by using enzymaticreactions such as PCR. In particular, a full-length-enriched cDNAlibrary, synthesized by methods such as oligo-capping, is desirable tosynthesize a full-length cDNA with more reliability.

The 5′-end sequence of the full-length cDNA clones of the invention canbe used to isolate the regulatory element of transcription including thepromoter on the genome. A rough draft of the human genome (analysis ofhuman genomic sequence with lower accuracy), which covers 90% of thegenome, has been reported (Nature, Vol. 409, 814-823, 2001), and by theyear 2003, analysis of the entire human genomic sequence is going to befinished. However, it is hard to analyze with software the transcriptionstart sites on the human genome, in which long introns exist. Bycontrast, it is easy to specify the transcription start site on thegenomic sequence using the nucleotide sequence which includes the 5′-endof the full-length cDNA clone of the present invention, and thus it iseasy to obtain the genomic region involved in transcription regulation,which includes the promoter that is contained in the upstream of thetranscription start site.

The polypeptide encoded by the full-length cDNA of the invention can beprepared as a recombinant polypeptide or as a natural polypeptide. Forexample, the recombinant polypeptide can be prepared by inserting thepolynucleotide encoding the polypeptide of the invention into a vector,introducing the vector into an appropriate host cell and purifying thepolypeptide expressed within the transformed host cell, as describedbelow. In contrast, the natural polypeptide can be prepared, forexample, by utilizing an affinity column to which an antibody againstthe polypeptide of the invention (Current Protocols in Molecular Biology(1987) Ausubel et al. edit, John Wiley & Sons, Section 16.1-16.19) isattached. The antibody used for affinity purification may be either apolyclonal antibody, or a monoclonal antibody. Alternatively, in vitrotranslation (See, for example, “On the fidelity of mRNA translation inthe nuclease-treated rabbit reticulocyte lysate system.” Dasso M. C.,and Jackson R. J. (1989) Nucleic Acids Res. 17: 3129-3144) may be usedfor preparing the polypeptide of the invention.

Polypeptides functionally equivalent to the polypeptides of the presentinvention can be prepared based on the activities, which were clarifiedin the above-mentioned manner, of the polypeptides of the presentinvention. Using the biological activity possessed by the polypeptide ofthe invention as an index, it is possible to verify whether or not aparticular polypeptide is functionally equivalent to the polypeptide ofthe invention by examining whether or not the polypeptide has saidactivity.

Polypeptides functionally equivalent to the polypeptides of the presentinvention can be prepared by those skilled in the art, for example, byusing a method for introducing mutations into an amino acid sequence ofa polypeptide (for example, site-directed mutagenesis (Current Protocolsin Molecular Biology, edit, Ausubel et al., (1987) John Wiley & Sons,Section 8.1-8.5) Besides, such polypeptides can be generated byspontaneous mutations. The present invention also includes a polypeptidecomprising the amino acid sequence shown in Table 1 in which one or moreamino acids are substituted, deleted, inserted, and/or added, as long asthe polypeptides have the equivalent functions to those of thepolypeptides identified in the present Examples described later.

There are no limitations on the number and sites of amino acidmutations, as long as the polypeptides maintain the functions thereof.The number of mutations typically corresponds to 30% or less, or 20% orless, or 10% or less, preferably 5% or less, or 3% or less of the totalamino acids, more preferably 2% or less or 1% or less of the total aminoacids. Alternatively, herein, substitution of one or more amino acidsincludes substitution of several amino acids. As used herein, the term“several amino acids” means, for example, 5 amino acids, preferably 4 or3 amino acids, more preferably 2 amino acids, and further preferably 1amino acid.

From the viewpoint of maintaining the polypeptide function, it ispreferable that a substituted amino acid has a similar property to thatof the original amino acid. For example, Ala, Val, Leu, Ile, Pro, Met,Phe and Trp are assumed to have similar properties to one anotherbecause they are all classified into a group of non-polar amino acids.Similarly, substitution can be performed among non-charged amino acidsuch as Gly, Ser, Thr, Cys, Tyr, Asn, and Gln, acidic amino acids suchas Asp and Glu, and basic amino acids such as Lys, Arg, and His.

In addition, polypeptides functionally equivalent to the polypeptides ofthe present invention can be isolated by using techniques ofhybridization or gene amplification known to those skilled in the art.Specifically, using the hybridization technique (Current Protocols inMolecular Biology, edit, Ausubel et al., (1987) John Wiley & Sons,Section 6.3-6.4)), those skilled in the art can usually isolate apolynucleotide highly homologous to the polynucleotide encoding thepolypeptide identified in the present Example based on the identifiednucleotide sequence (Table 1) or a portion thereof and obtain thefunctionally equivalent polypeptide from the isolated polynucleotide.The present invention include polypeptides encoded by thepolynucleotides hybridizing with the polynucleotides encoding thepolypeptides identified in the present Example, as long as thepolypeptides are functionally equivalent to the polypeptides identifiedin the present Example. Organisms from which the functionally equivalentpolypeptides are isolated are illustrated by vertebrates such as human,mouse, rat, rabbit, pig and bovine, but are not limited to theseanimals.

Washing conditions of hybridization for the isolation of polynucleotidesencoding the functionally equivalent polypeptides are usually “1×SSC,0.1% SDS, 37° C.”; more stringent conditions are “0.5×SSC, 0.1% SDS, 42°C.”; and still more stringent conditions are “0.1×SSC, 0.1% SDS, 65°C.”. Alternatively, the following conditions can be given ashybridization conditions of the present invention. Namely, conditions inwhich the hybridization is done at “6×SSC, 40% Formamide, 25° C.”, andthe washing at “1×SSC, 55° C.” can be given. More preferable conditionsare those in which the hybridization is done at “6×SSC, 40% Formamide,37° C.”, and the washing at “0.2×SSC, 55° C.”. Even more preferable arethose in which the hybridization is done at “6×SSC, 50% Formamide, 37°C.”, and the washing at “0.1×SSC, 62° C.”. The more stringent theconditions of hybridization are, the more frequently the polynucleotideshighly homologous to the probe sequence are isolated. Therefore, it ispreferable to conduct hybridization under stringent conditions. Examplesof stringent conditions in the present invention are, washing conditionsof “0.5×SSC, 0.1% SDS, 42° C.”, or alternatively, hybridizationconditions of “6×SSC, 40% Formamide, 37° C.”, and the washing at“0.2×SSC, 55° C.”.

One skilled in the art can suitably select various conditions, such asdilution ratios of SSC, formamide concentrations, and temperatures toaccomplish a similar stringency.

However, the above-mentioned combinations of SSC, SDS and temperatureconditions are indicated just as examples. Those skilled in the art canselect the hybridization conditions with similar stringency to thosementioned above by properly combining the above-mentioned or otherfactors (for example, probe concentration, probe length and duration ofhybridization reaction) that determines the stringency of hybridization.

The amino acid sequences of polypeptides isolated by using thehybridization techniques usually have high identity to those of thepolypeptides of the present invention, which are shown in Table 1. Thepresent invention encompasses a polynucleotide comprising a nucleotidesequence that has a high identity to the nucleotide sequence of claim 1(a). Furthermore, the present invention encompasses a peptide, orpolypeptide comprising an amino acid sequence that has a high identityto the amino acid sequence encoded by the polynucleotide of claim 1 (b).The term “high identity” indicates sequence identity of at least 40% ormore; preferably 60% or more; and more preferably 70% or more.Alternatively, more preferable is identity of 90% or more, or 93% ormore, or 95% or more, furthermore, 97% or more, or 99% or more. Theidentity can be determined by using the BLAST search algorithm.

As used herein, “percent identity” of amino acid sequences or nucleicacids is determined using the algorithm BLAST of Karlin and Altschul(Proc. Natl. Acad. Sci. USA 90:5873-5877, 1993). Such an algorithm isincorporated into the BLASTN and BLASTX programs of Altschul et al. (J.Mol. Biol. 215:403-410, 1990). BLAST nucleotide searches are performedwith the BLASTN program, for example, score=100, wordlength=12. BLASTprotein searches are performed with the BLASTX program, for example,score=50, wordlength=3. When utilizing BLAST and Gapped BLAST programs,the default parameters of the respective programs are used. Seehttp://www.ncbi.nlm.nih.gov.

With the gene amplification technique (PCR) (Current Protocols inMolecular Biology, edit, Ausubel et al., (1987) John Wiley & Sons,Section 6.1-6.4)) using primers designed based on the nucleotidesequence (Table 1) or a portion thereof identified in the presentExample, it is possible to isolate a polynucleotide fragment highlyhomologous to the polynucleotide sequence or a portion thereof and toobtain functionally equivalent polypeptide to a particular polypeptideidentified in the present Example based on the isolated polynucleotidefragment.

The present invention also provides a polynucleotide containing at least15 nucleotides complementary to a polynucleotide comprising a nucleotidesequence of SEQ ID NOs shown in Table 1 or the complementary strandthereof. Herein, the term “complementary strand” is defined as onestrand of a double strand DNA composed of A:T and G:C base pair to theother strand. Also, “complementary” is defined as not only thosecompletely matching within a continuous region of at least 15nucleotides, but also having a identity of at least 70%, favorably 80%or higher, more favorably 90% or higher, and most favorably 95% orhigher within that region. The identity may be determined using thealgorithm described herein.

Such a polynucleotide includes probes and primers used for the detectionand amplification of a polynucleotide encoding the inventivepolypeptide. When used as a primer, the polynucleotide usually comprises15 to 100 bp, and preferably of 15 to 35 bp. When used as a probe, thepolynucleotide comprises the whole or a part of the sequence of apolynucleotide of the invention, and comprises at least 15 bp. When usedas primers, such polynucleotides are complementary at the 3′-end, andrestriction enzyme recognition sequences or tags can be added to the5′-end.

Furthermore, polynucleotides of the present invention include anantisense polynucleotide for suppressing the expression of a polypeptideof the invention, which comprises an amino acid sequence of SEQ ID NOsshown in Table 1. To exert an antisense effect, an antisensepolynucleotide has at least 15 bp or more, for example 50 bp or more,preferably 100 bp or more, and more preferably 500 bp or more, andusually has 3000 bp or less, and preferably 2000 bp or less. Antisensepolynucleotides can be used in the gene therapy of diseases caused byabnormalities of the polypeptides of the invention (abnormal function orabnormal expression). An antisense polynucleotide can be prepared, forexample, by the phosphorothioate method (“Physicochemical properties ofphosphorothioate oligodeoxynucleotides.” Stein (1988) Nucleic Acids Res.16: 3209-3221) based on the sequence information of polynucleotideencoding a polypeptide of the invention (for example, the nucleotidesequences of SEQ ID NO: 1 to 1970).

The polynucleotides or antisense polynucleotides of the presentinvention can be used in, for example, gene therapy. As target diseases,for example, cancers or various inflammatory diseases may be preferable.These molecules can be used for gene therapy, for example, byadministrating them to patients by the in vivo or ex vivo method usingvirus vectors such as retrovirus vectors, adenovirus vectors, andadeno-related virus vectors, or non-virus vectors such as liposomes.

The present invention also includes a partial peptide of thepolypeptides of the invention. The partial peptide comprises apolypeptide generated as a result that a signal peptide has been removedfrom a secretory protein. If the polypeptide of the present inventionhas an activity as a receptor or a ligand, the partial peptide mayfunction as a competitive inhibitor of the polypeptide and may bind tothe receptor (or ligand). In addition, the present invention includes anantigen peptide for raising antibodies. For the peptides to be specificfor the polypeptide of the invention, the peptides comprise at least 7amino acids, preferably 8 amino acids or more, more preferably 9 aminoacids or more, and even more preferably 10 amino acids or more. Thepeptide can be used for preparing antibodies against the polypeptide ofthe invention, or competitive inhibitors of them, and also screening fora receptor that binds to the polypeptide of the invention. The partialpeptides of the invention can be produced, for example, by geneticengineering methods, known methods for synthesizing peptides, ordigesting the polypeptide of the invention with an appropriatepeptidase.

The present invention also relates to a vector into which apolynucleotide of the invention is inserted. The vector of the inventionis not limited as long as it contains the inserted polynucleotidestably. For example, if E. coli is used as a host, vectors such aspBluescript vector (Stratagene) are preferable as a cloning vector. Toproduce the polypeptide of the invention, expression vectors areespecially useful. Any expression vector can be used as long as it iscapable of expressing the polypeptide in vitro, in E. coli, in culturedcells, or in vivo. For example, pBEST vector (Promega) is preferable forin vitro expression, pET vector (Invitrogen) for E. coli, pME18S-FL3vector (GenBank Accession No. AB009864) for cultured cells, and pME18Svector (Mol. Cell. Biol. (1988) 8: 466-472) for in vivo expression. Toinsert the polynucleotide of the invention, ligation utilizingrestriction sites can be performed according to the standard method(Current Protocols in Molecular Biology (1987) Ausubel et al. edit, JohnWiley & Sons, Section 11.4-11.11).

Recently, the technique of GATEWAY™ system (Invitrogen), which is anexpression vector construction system for polypeptide expression, hasbeen developed (Experimental Medicine, Vol. 18, No. 19 (December),p2716-2717, 2000). This system includes two types of site-specificrecombinases (BP CLONASE™ and LR CLONASE™) derived from lambda phage anduses BP CLONASE™-specific recombination sites for an Entry Vector and LRCLONASE™-specific recombination sites for a Destination Vector, whichmay comprise a tag useful for polypeptide purification. With thissystem, an expression vector can be obtained by using homologousrecombination.

First, a polynucleotide fragment of interest is inserted into the entryvector using the first recombination. Then, the secondary recombinationis allowed to take place between the entry vector, where thepolynucleotide fragment of interest has been inserted, and thedestination vector. Thus, the expression vector can be prepared rapidlyand highly efficiently. With the above-mentioned typical method usingrestriction enzyme and ligase reactions, the step of expression vectorconstruction and expression of polypeptide of interest takes about 7 to10 days. However, with the GATEWAY™ system, the polypeptide of interestcan be expressed and prepared in only 3 to 4 days. Thus, the systemensures a high-throughput functional analysis for expressed polypeptides(http://biotech.nikkeibp.co.jp/netlink/lto/gateway/).

The present invention also relates to a transformant carrying the vectorof the invention. Any cell can be used as a host into which the vectorof the invention is inserted, and various kinds of host cells can beused depending on the purposes. For strong expression of the polypeptidein eukaryotic cells, COS cells or CHO cells can be used, for example.

Introduction of the vector into host cells can be performed, forexample, by calcium phosphate precipitation method, electroporationmethod (Current Protocols in Molecular Biology (1987) Ausubel et al.edit, John Wiley & Sons, Section 9.1-9.9), lipofectamine method(GIBCO-BRL), or microinjection method, etc.

Further, a polynucleotide containing at least 15 nucleotides comprisinga nucleotide sequence of any one of the polynucleotides comprising thenucleotide sequences of SEQ ID NOs shown in Table 1 or the complementarystrand thereof can be used not only as a primer for synthesizingfull-length cDNAs but also for testing and diagnosing the abnormalitiesof the polypeptide encoded by the full-length cDNA of the presentinvention. For example, by utilizing polymerase chain reaction (genomicDNA-PCR, or RT-PCR) using the polynucleotide of the invention as aprimer, polynucleotide encoding the polypeptide of the invention can beamplified. It is also possible to obtain the regulatory region ofexpression in the 5′-upstream by using PCR or hybridization since thetranscription start site within the genomic sequence can be easilyspecified based on the 5′-end sequence of the full-length cDNA. Theobtained genomic region can be used for detection and/or diagnosis ofthe abnormality of the sequence by RFLP analysis, SSCP, or sequencing.Especially, in the case where expression of the mRNA of the presentinvention varies according to a specific disease, analysis of the amountof expression of the mRNA using the polynucleotide of the presentinvention as a probe or a primer enables detection and diagnosis of thedisease.

The present invention also relates to antibodies that bind to thepolypeptide of the invention. There are no limitations in the form ofthe antibodies of the invention. They include polyclonal antibodies,monoclonal antibodies, or their portions that can bind to an antigen.They also include antibodies of all classes. Furthermore, specialantibodies such as humanized antibodies and chimeric antibodies are alsoincluded.

The polyclonal antibody of the invention can be obtained according tothe standard method by synthesizing an oligopeptide corresponding to theamino acid sequence and immunizing rabbits with the peptide (CurrentProtocols in Molecular Biology (1987) Ausubel et al. edit, John Wiley &Sons, Section 11.12-11.13). The monoclonal antibody of the invention canbe obtained according to the standard method by purifying thepolypeptide expressed in E. coli, immunizing mice with the polypeptide,and producing a hybridoma cell by fusing the spleen cells and myelomacells (Current Protocols in Molecular Biology (1987) Ausubel et al.edit, John Wiley & Sons, Section 11.4-11.11).

The antibody binding to the polypeptide of the present invention can beused for purification of the polypeptide of the invention, and also fordetection and/or diagnosis of the abnormalities of the expression andstructure of the polypeptide. Specifically, polypeptides can beextracted, for example, from tissues, blood, or cells, and thepolypeptide of the invention is detected by Western blotting,immunoprecipitation, or ELISA, etc. for the above purpose.

Furthermore, the antibody binding to the polypeptide of the presentinvention can be utilized for treating the diseases that associates withthe polypeptide of the invention. If the antibodies are used fortreating patients, human antibodies, humanized antibodies, or chimericantibodies are preferable in terms of their low antigenicity. The humanantibodies can be prepared by immunizing a mouse whose immune system isreplaced with that of human (e.g., see “Functional transplant ofmegabase human immunoglobulin loci recapitulates human antibody responsein mice” Mendez, M. J. et al. (1997) Nat. Genet. 15: 146-156). Thehumanized antibodies can be prepared by recombination of thehypervariable region of a monoclonal antibody (Methods in Enzymology(1991) 203: 99-121).

A cDNA of the present invention encodes, for example, an amino acidsequence of a protein that is predicted to have the following function.The use of the amino acid sequences of the polypeptides encoded by thecDNAs of the present invention enables predicting that the polypeptideshave the following functions. It can be predict, from the results ofhomology search of SwissProt, GenBank, UniGene, or nr, that thesepolypeptides have such functions. Specifically, for instance, as shownin Examples, searching for a known gene or polypeptide that ishomologous to the partial sequence of the full-length cDNA of theinvention (1970 clone) and referring the function of the gene and of thepolypeptide encoded by the gene make it possible to predict the functionof the polypeptide encoded by the cDNA of the invention. In this way,each of 1078 clones out of the 1970 full-length cDNA clones of theinvention was predicted to encode a polypeptide that was classified intothe following categories.

-   -   Secretory and/or membrane protein (516 clones)    -   Glycoprotein-related protein (121 clones)    -   Signal transduction-related protein (88 clones)    -   Transcription-related protein (143 clones)    -   Disease-related protein (331 clones)    -   Enzyme and/or metabolism-related protein (219 clones)    -   Cell division- and/or cell proliferation-related protein (44        clones)    -   Cytoskeleton-related protein (80 clones)    -   Nuclear protein and/or RNA synthesis-related protein (70 clones)    -   Protein synthesis- and/or transport-related protein (20 clones)    -   Cellular defense-related protein (10 clones)    -   Development and/or differentiation-related protein (19 clones)    -   DNA- and/or RNA-binding protein (168 clones)    -   ATP- and/or GTP-binding protein (93 clones)

The functions of the polypeptides encoded by the cDNAs of the presentinvention can be predicted by assessing the presence of signal sequence,transmembrane region, nuclear translocation signal, glycosylationsignal, phosphorylation site, and zinc finger motif, SH3 domain, etc. inthe amino acid sequences. The programs, PSORT (Nakai K., and Kanehisa M.(1992) Genomics 14: 897-911), SOSUI (Hirokawa T. et al. (1998)Bioinformatics 14: 378-379) (Mitsui Knowledge Industry), and MEMSAT(Jones D. T., Taylor W. R., and Thornton J. M. (1994) Biochemistry 33:3038-3049) can be used to predict the existence of the signal sequenceor transmembrane region. Alternatively, a partial amino acid sequence ofthe polypeptide is fused with another polypeptide such as GFP, thefusion polypeptide is transfected into cultured cells, and thelocalization is analyzed to predict the function of the originalpolypeptide.

Based on the determined nucleotide sequences of the full-length cDNAsobtained in the present invention, it is possible to predict moredetailed functions of the polypeptides encoded by the cDNA clones, forexample, by searching the databases such as GenBank, Swiss-Prot,UniGene, and nr for homologies of the cDNAs; or by searching the aminoacid sequences deduced from the full-length cDNAs for signal sequencesby using software programs such as PSORT, for transmembrane regions byusing software programs such as SOSUI or for motifs by using softwareprograms such as Pfam(http://www.sanger.ac.uk/Software/Pfam/index.shtml) and PROSITE(http://www.expasy.ch/prosite/). As a matter of course, the functionsare often predictable by using partial sequence information (preferably300 nucleotides or more) instead of the full-length nucleotidesequences. However, the result of the prediction by using partialnucleotide sequence does not always agree with the result obtained byusing full-length nucleotide sequence, and thus, it is needless to saythat the prediction of function is preferably performed based on thefull-length nucleotide sequences.

GenBank, Swiss-Prot, UniGene and nr databases were searched forhomologies of the full-length nucleotide sequences of the 1970 clones(see Example 6). The amino acid sequences deduced from the full-lengthnucleotide sequences were searched for functional domains by PSORT,SOSUI and Pfam. Prediction of functions of polypeptides encoded by theclones and the categorization thereof were performed based on theseresults obtained. The categorization was carried out by the followingmethod.

[1] Firstly, the cDNA clones were classified into the above-mentioned 14functional categories based on the results of annotation-basedcategorization (using the keywords in the case of Swiss-Prot hit data;using Definition or Reference information in the case of GenBank,UniGene, or nr hit data), and the signal sequence search of the deducedORFs by PSORT and the transmembrane region search by SOSUI.

[2] Secondly, clones which had been unassignable to the categories bythe method of [1] were searched for functional domains and/or motifs byPfam. Based on the results, the clones were additionally classified intothe above-mentioned 14 types of categories when they had a functionaldomain and/or motif assignable to any one of the categories.

The following 516 clones presumably belong to secretory and/or membraneproteins. ADRGL20020290, ADRGL20021910, ADRGL20036380, ADRGL20036840,ADRGL20059610, ADRGL20063770, ADRGL20066770, ASTRO20010010,ASTRO20020240, ASTRO20045840, ASTRO20053430, ASTRO20055530,ASTRO20055570, ASTRO20055930, ASTRO20088950, ASTRO20091180,BNGH420021680, BNGH420023870, BNGH420046790, BNGH420052350,BNGH420059680, BNGH420075940, BNGH420077980, BRACE10000510,BRACE20051930, BRACE20052530, BRACE20054080, BRACE20066360,BRACE20068710, BRACE20069000, BRACE20069110, BRACE20194670,BRACE20204670, BRACE20216950, BRAMY10001730, BRAMY20003880,BRAMY20013670, BRAMY20024790, BRAMY20027390, BRAMY20028530,BRAMY20035380, BRAMY20044920, BRAMY20045210, BRAMY20047560,BRAMY20050940, BRAMY20053910, BRAMY20055760, BRAMY20072440,BRAMY20083820, BRAMY20089770, BRAMY20091230, BRAMY20094890,BRAMY20096930, BRAMY20118410, BRAMY20123400, BRAMY20125550,BRAMY20127310, BRAMY20127760, BRAMY20135720, BRAMY20137360,BRAMY20139440, BRAMY20152510, BRAMY20194680, BRAMY20204270,BRAMY20225320, BRAMY20237190, BRAMY20245140, BRAMY20251750,BRAMY20285650, BRAWH20020470, BRAWH20021910, BRAWH20026010,BRAWH20030000, BRAWH20039640, BRAWH20055330, BRAWH20078620,BRAWH20093070, BRAWH20185270, BRCAN10000760, BRCAN10001680,BRCAN20001480, BRCAN20004180, BRCAN20005230, BRCOC20000470,BRCOC20003600, BRHIP10000720, BRHIP10001040, BRHIP20000210,BRSSN20001970, BRSSN20074640, BRSSN20091190, CD34C20001750,CTONG20017490, CTONG20036990, CTONG20041260, CTONG20044870,CTONG20045500, CTONG20049480, CTONG20051450, CTONG20055850,CTONG20056150, CTONG20059130, CTONG20060040, CTONG20063770,CTONG20065680, CTONG20068360, CTONG20069320, CTONG20071680,CTONG20076810, CTONG20078340, CTONG20079590, CTONG20083980,CTONG20084020, CTONG20085210, CTONG20167750, CTONG20168240,CTONG20179890, CTONG20183830, CTONG20184830, DFNES20018000,DFNES20029660, DFNES20057660, DFNES20072990, DFNES20080880,FCBBF20018680, FCBBF20029280, FCBBF20032930, FCBBF20036360,FCBBF20054390, FCBBF30004340, FCBBF30022680, FCBBF30029250,FCBBF30042610, FCBBF30062490, FCBBF30075970, FCBBF30078600,FCBBF30091520, FCBBF30095410, FCBBF30105440, FCBBF30118670,FCBBF30132660, FCBBF30135890, FCBBF30145670, FCBBF30164510,FCBBF30169870, FCBBF30171230, FCBBF30172330, FCBBF30177290,FCBBF30179740, FCBBF30195690, FCBBF30197840, FCBBF30212210,FCBBF30223110, FCBBF30223210, FCBBF30225930, FCBBF30230610,FCBBF30260480, FCBBF30266510, FCBBF30287940, FCBBF50000610,FCBBF50004950, FEBRA20007820, FEBRA20018670, FEBRA20031280,FEBRA20031810, FEBRA20038220, FEBRA20039260, FEBRA20040230,FEBRA20040560, FEBRA20046280, FEBRA20080860, FEBRA20084750,FEBRA20088810, FEBRA20115930, FEBRA20116650, FEBRA20121950,FEBRA20141980, FEBRA20177800, FEBRA20182030, FEBRA20191720,HCHON10001660, HCHON20015050, HEART10001490, HEART20031680,HHDPC10001140, HHDPC20051850, HHDPC20082790, HHDPC20088160,HLUNG20015070, HLUNG20015180, HLUNG20020850, HLUNG20029490,HLUNG20032460, HLUNG20033350, HLUNG20034970, HLUNG20037160,HLUNG20041540, HLUNG20042730, HLUNG20050760, HLUNG20052300,HLUNG20060670, HLUNG20065990, HLUNG20074330, HLUNG20081390,HLUNG20088750, HLUNG20092530, KIDNE20016360, KIDNE20083150,KIDNE20084030, KIDNE20084040, KIDNE20084800, KIDNE20086490,KIDNE20086660, KIDNE20094670, KIDNE20134130, KIDNE20142900,KIDNE20143200, KIDNE20148080, KIDNE20160960, KIDNE20163710,KIDNE20169180, KIDNE20182540, KIDNE20186170, KIDNE20188630,KIDNE20189960, LIVER20007750, LIVER20010510, LIVER20010990,LIVER20026440, LIVER20030650, LIVER20038000, MESAN20007110,MESAN20008150, MESAN20021220, MESAN20027900, MESAN20058110,MESAN20059570, MESAN20060430, MESAN20067430, MESAN20084150,MESAN20095220, NT2NE20018740, NT2NE20021860, NT2NE20039210,NT2NE20053230, NT2NE20059210, NT2NE20064780, NT2NE20069580,NT2NE20080770, NT2NE20082130, NT2NE20092950, NT2NE20140130,NT2NE20145250, NT2NE20146510, NT2NE20152620, NT2NE20167660,NT2NE20181800, NT2RI20016240, NT2RI20021200, NT2RI20033920,NT2RP70003110, NT2RP70027790, NT2RP70031070, NT2RP70031480,NT2RP70056690, NT2RP70087140, NTONG20034540, NTONG20053630,OCBBF20000740, OCBBF20012520, OCBBF20109780, OCBBF20110210,OCBBF20110730, OCBBF20112280, OCBBF20118720, OCBBF20120010,OCBBF20123200, OCBBF20155030, OCBBF20165900, OCBBF20165910,OCBBF20170350, OCBBF20176650, OCBBF20185630, OCBBF20191950,PANCR10000860, PEBLM20001800, PLACE50001290, PLACE60004260,PLACE60006300, PLACE60053280, PLACE60055590, PLACE60056910,PLACE60057860, PLACE60061370, PLACE60064740, PLACE60070500,PLACE60087680, PLACE60104630, PLACE60107010, PLACE60113340,PLACE60138840, PLACE60154450, PLACE60184870, PROST10001100,PROST20011160, PROST20014150, PROST20035830, PROST20045700,PROST20050390, PROST20065100, PROST20073280, PROST20082430,PROST20084680, PROST20084720, PROST20099090, PROST20105450,PROST20106060, PROST20108850, PROST20110120, PROST20114100,PROST20146590, PROST20152510, PROST20168600, PUAEN10000870,SKMUS20006790, SKMUS20020770, SKMUS20073150, SKMUS20091900,SKNMC20006350, SKNSH20094350, SMINT20006090, SMINT20008110,SMINT20024140, SMINT20028840, SMINT20045470, SMINT20077960,SMINT20081330, SMINT20086250, SMINT20088440, SMINT20088690,SMINT20092160, SPLEN20015100, SPLEN20017610, SPLEN20017810,SPLEN20024190, SPLEN20024620, SPLEN20054500, SPLEN20058180,SPLEN20063890, SPLEN20073880, SPLEN20080070, SPLEN20090880,SPLEN20101950, SPLEN20104690, SPLEN20105100, SPLEN20108000,SPLEN20110180, SPLEN20110860, SPLEN20118050, SPLEN20121790,SPLEN20125230, SPLEN20136700, SPLEN20138600, SPLEN20139100,SPLEN20175920, SPLEN20177400, SPLEN20182850, SPLEN20183020,SPLEN20183950, SPLEN20190080, SPLEN20190770, SPLEN20193230,SPLEN20193490, SPLEN20193790, SPLEN20201830, SPLEN20204670,TESOP10000350, TESTI10000190, TESTI20006160, TESTI20029100,TESTI20031310, TESTI20032770, TESTI20038240, TESTI20043130,TESTI20043220, TESTI20045390, TESTI20046540, TESTI20046870,TESTI20047370, TESTI20050400, TESTI20051200, TESTI20051730,TESTI20053260, TESTI20053780, TESTI20057200, TESTI20057590,TESTI20059080, TESTI20061200, TESTI20062120, TESTI20063330,TESTI20063410, TESTI20063600, TESTI20066330, TESTI20068530,TESTI20070400, TESTI20070740, TESTI20073460, TESTI20086840,TESTI20095200, TESTI20095440, TESTI20095880, TESTI20100090,TESTI20102390, TESTI20105910, TESTI20113940, TESTI20116120,TESTI20121040, TESTI20121710, TESTI20131440, TESTI20142540,TESTI20149880, TESTI20151800, TESTI20162780, TESTI20170170,TESTI20173050, TESTI20182760, TESTI20183680, TESTI20184750,TESTI20186110, TESTI20198540, TESTI20199110, TESTI20202830,TESTI20204260, TESTI20210030, TESTI20214630, TESTI20219110,TESTI20244730, TESTI20245600, TESTI20245860, TESTI20246410,TESTI20251610, TESTI20257910, TESTI20260640, TESTI20261040,TESTI20262150, TESTI20262940, TESTI20264910, TESTI20271790,TESTI20278280, TESTI20282420, TESTI20282900, TESTI20286590,THYMU20007020, THYMU20012020, THYMU20017270, THYMU20020800,THYMU20025480, THYMU20028150, THYMU20030690, THYMU20034790,THYMU20046350, THYMU20046770, THYMU20050010, THYMU20052830,THYMU20054800, THYMU20055740, THYMU20055760, THYMU20062770,THYMU20078240, THYMU20079690, THYMU20083390, THYMU20087270,THYMU20100940, THYMU20115380, THYMU20137050, THYMU20137570,THYMU20143230, THYMU20150190, THYMU20153210, THYMU20154790,THYMU20163600, THYMU20171580, THYMU20178440, THYMU20185470,TRACH20011010, TRACH20011540, TRACH20021380, TRACH20073990,TRACH20081270, TRACH20090060, TRACH20149720, TRACH20149740,TRACH20159390, TRACH20163470, TRACH20165330, TRACH20167090,TRACH20173680, TRACH20190460, UMVEN10001380, UTERU20035770,UTERU20040150, UTERU20045200, UTERU20064120, UTERU20086530,UTERU20087070, UTERU20087850, UTERU20089300, UTERU20089620,UTERU20095100, UTERU20099040, UTERU20103200, UTERU20125810,UTERU20127030, UTERU20127150, UTERU20139760, UTERU20188840

The following 121 clones presumably belong to glycoprotein-relatedproteins. ADRGL20020290, ADRGL20036840, ADRGL20059610, ADRGL20066770,ASTRO20055570, BNGH420046790, BNGH420077980, BRACE20051930,BRACE20069000, BRACE20204670, BRACE20216950, BRAMY20013670,BRAMY20089770, BRAMY20251210, BRAWH20039640, BRCAN10000760,BRCAN20005230, BRCOC20003600, CD34C20001750, CTONG20017490,CTONG20036990, CTONG20045500, CTONG20059130, CTONG20079590,CTONG20085210, CTONG20184830, DFNES20018000, DFNES20080880,FCBBF30004340, FCBBF30029250, FCBBF30062490, FCBBF30091520,FCBBF30164510, FCBBF30171230, FCBBF30195690, FCBBF30223210,FEBRA20038220, HCHON20015050, HLUNG20015070, HLUNG20032460,HLUNG20037160, HLUNG20041540, KIDNE20142900, KIDNE20169180,KIDNE20186170, KIDNE20189960, MESAN20021220, MESAN20058110,NT2NE20064780, NT2NE20140130, NT2NE20155650, NT2RP70056690,NTONG20053630, OCBBF20000740, OCBBF20012520, OCBBF20110210,OCBBF20120010, OCBBF20165900, OCBBF20165910, OCBBF20191950,PEBLM20001800, PLACE60004260, PLACE60087680, PLACE60113340,PLACE60184870, PROST20033240, PROST20099090, PROST20108850,PROST20146590, SKMUS20073150, SKNMC20006350, SMINT20028840,SMINT20056230, SMINT20083290, SMINT20091190, SPLEN20024620,SPLEN20063890, SPLEN20080070, SPLEN20090880, SPLEN20118050,SPLEN20139100, SPLEN20183020, SPLEN20201830, TESTI10000190,TESTI20031310, TESTI20043990, TESTI20045390, TESTI20051200,TESTI20057590, TESTI20059080, TESTI20066330, TESTI20086840,TESTI20100090, TESTI20105910, TESTI20154370, TESTI20164210,TESTI20182760, TESTI20184750, TESTI20199110, TESTI20219110,TESTI20220230, TESTI20245600, TESTI20251610, TESTI20257910,TESTI20286590, THYMU20024500, THYMU20028150, THYMU20052830,THYMU20062770, THYMU20099060, THYMU20170080, THYMU20178440,TRACH20011010, TRACH20011540, TRACH20021380, TRACH20149740,TRACH20170860, TRACH20190460, UTERU20086530, UTERU20087070,UTERU20127030

The following 88 clones presumably belong to signal transduction-relatedproteins. ASTRO20050810, ASTRO20052420, ASTRO20085080, ASTRO20090680,BNGH420008150, BNGH420015760, BNGH420035290, BNGH420086030,BRAMY20035830, BRAMY20043630, BRAMY20118490, BRAMY20206340,BRAMY20244490, BRAMY20251210, BRAMY20263000, BRAWH20093040,BRAWH20190550, CTONG20004520, CTONG20029030, CTONG20030280,CTONG20063930, CTONG20070720, CTONG20189000, FCBBF30001100,FCBBF30076310, FCBBF30100080, FCBBF30143550, FCBBF30153170,FCBBF30175350, FCBBF30250980, FEBRA20090160, FEBRA20173330,HCHON20000870, HLUNG20011260, HLUNG20084790, KIDNE20089870,KIDNE20160360, LIVER20011640, MESAN20021130, MESAN20027240,MESAN20065990, NT2NE20018890, NT2NE20042550, NT2R270075800,NTONG20043080, NTONG20048440, PLACE60071800, PROST20033240,PROST20052850, PROST20065790, PROST20075280, SKNSH20052400,SKNSH20057920, SMINT20006020, SMINT20035050, SPLEN20023540,SPLEN20039180, SPLEN20048800, SPLEN20049840, SPLEN20054160,SPLEN20085910, SPLEN20191020, SPLEN20198390, TESTI20046490,TESTI20049060, TESTI20053070, TESTI20066650, TESTI20081890,TESTI20095770, TESTI20106820, TESTI20112860, TESTI20145780,TESTI20150420, TESTI20168880, TESTI20205250, TESTI20228120,TESTI20244220, TESTI20244460, TESTI20251740, TESTI20261160,TESTI20264530, THYMU20013250, THYMU20039320, THYMU20106990,THYMU20145990, THYMU20170080, THYMU20176010, TRACH20188350

The following 143-clones presumably belong to transcription-relatedproteins. ASTRO20038400, ASTRO20075150, BNGH420070370, BNGH420074600,BNGH420087430, BRACE20003310, BRACE20061620, BRAMY20001510,BRAMY20040580, BRAMY20076100, BRAMY20111780, BRAWH20040680,BRAWH20050740, BRAWH20080580, BRAWH20082920, BRAWH20095900,BRSSN20066440, CTONG20020950, CTONG20044230, CTONG20053990,CTONG20072930, CTONG20074000, CTONG20084660, CTONG20186370,CTONG20186520, DFNES20028170, DFNES20046840, DFNES20073320,FCBBF30003610, FCBBF30019140, FCBBF30021900, FCBBF30093170,FCBBF30114850, FCBBF30129010, FCBBF30136230, FCBBF30143550,FCBBF30220050, FCBBF30228940, FCBBF30263080, FCBBF30285930,FCBBF50003530, FEBRA20026820, FEBRA20027070, FEBRA20046510,FEBRA20057010, FEBRA20063720, FEBRA20170240, HCHON10000150,HCHON20002650, HEART20019310, HLUNG20014590, HLUNG20028110,HLUNG20063700, KIDNE20140870, LIVER20006260, MESAN20016270,MESAN20038520, NT2NE20038870, NT2NE20053950, NT2NE20060750,NT2NE20061030, NT2NE20079670, NT2NE20082600, NT2RP70001120,NT2RP70029780, NT2RP70046410, NT2RP70057500, NT2RP70075300,NT2RP70090870, OCBBF20116250, OCBBF20120950, OCBBF20121910,OCBBF20156450, OCBBF20157970, OCBBF20166900, OCBBF20175360,OCBBF20177540, PEBLM20003260, PLACE60052940, PLACE60066970,PLACE60122970, PLACE60150510, PLACE60177880, PROST20007170,PROST20024250, PROST20035170, PROST20127450, PROST20151370,PROST20155370, PUAEN10000650, PUAEN20003120, SMINT20011950,SMINT20026200, SMINT20030740, SMINT20039050, SMINT20044140,SMINT20086720, SPLEN20042200, SPLEN20043680, SPLEN20055600,SPLEN20059270, SPLEN20063250, SPLEN20098030, SPLEN20197930,TESTI10001570, TESTI20057430, TESTI20057840, TESTI20059810,TESTI20067480, TESTI20068790, TESTI20075240, TESTI20079220,TESTI20088840, TESTI20104090, TESTI20122070, TESTI20166670,TESTI20171070, TESTI20173960, TESTI20184760, TESTI20194880,TESTI20197600, TESTI20228740, TESTI20254030, TESTI20254990,TESTI20266050, TESTI20274960, TESTI20282530, THYMU10004280,THYMU20019260, THYMU20032820, THYMU20071120, THYMU20077250,TKIDN10001920, UTERU20016580, UTERU20026620, UTERU20041630,UTERU20094830, UTERU20099510, UTERU20101150, UTERU20169020,UTERU20177150, UTERU20185220, UTERU20188670

The following 331 clones presumably belong to disease-related proteins.ADRGL20020290, ADRGL20021910, ADRGL20026790, ADRGL20036840,ADRGL20059610, ADRGL20066770, ASTRO20038400, ASTRO20052420,ASTRO20055570, ASTRO20075150, ASTRO20088950, BNGH420008150,BNGH420086030, BRACE10000510, BRACE20003310, BRACE20069000,BRACE20097540, BRACE20194670, BRACE20196180, BRACE20204670,BRACE20216950, BRAMY20003540, BRAMY20005080, BRAMY20035830,BRAMY20040580, BRAMY20043630, BRAMY20044920, BRAMY20051820,BRAMY20056620, BRAMY20089770, BRAMY20111780, BRAMY20152510,BRAMY20190550, BRAMY20221600, BRAMY20227860, BRAMY20274510,BRAWH20082920, BRAWH20093040, BRAWH20095900, BRAWH20190530,BRAWH20191980, BRCAN10000760, BRCAN10001050, BRCAN20005230,BRSSN20066440, CTONG20004520, CTONG20029030, CTONG20042640,CTONG20045500, CTONG20052780, CTONG20053990, CTONG20070780,CTONG20070910, CTONG20072930, CTONG20083980, CTONG20084660,CTONG20165750, CTONG20169040, CTONG20183430, CTONG20183830,CTONG20186290, CTONG20189000, DFNES20016470, DFNES20025500,DFNES20046840, DFNES20055400, DFNES20080880, FCBBF10000230,FCBBF20035490, FCBBF20066340, FCBBF30002270, FCBBF30002280,FCBBF30019140, FCBBF30053300, FCBBF30071500, FCBBF30072440,FCBBF30076310, FCBBF30080730, FCBBF30100080, FCBBF30115920,FCBBF30118670, FCBBF30129010, FCBBF30132050, FCBBF30136230,FCBBF30153170, FCBBF30164510, FCBBF30166220, FCBBF30171230,FCBBF30175350, FCBBF30194550, FCBBF30220050, FCBBF30223210,FCBBF30259050, FCBBF30263080, FCBBF30275590, FCBBF50001650,FEBRA20027070, FEBRA20045380, FEBRA20046200, FEBRA20046510,FEBRA20057010, FEBRA20063720, FEBRA20078800, FEBRA20087550,FEBRA20088810, FEBRA20090160, FEBRA20092760, FEBRA20151750,FEBRA20170240, FEBRA20173330, FEBRA20191720, HCHON10000150,HCHON20015050, HEART20009590, HEART20022200, HEART20063100,HHDPC20081230, HLUNG20008460, HLUNG20014590, HLUNG20032460,HLUNG20063700, HLUNG20065990, HLUNG20069350, HLUNG20081530,HLUNG20082350, HLUNG20083330, HLUNG20085210, KIDNE20081170,KIDNE20084040, KIDNE20088240, KIDNE20089870, KIDNE20133460,KIDNE20134890, KIDNE20141700, KIDNE20142900, KIDNE20150730,KIDNE20152440, KIDNE20160360, KIDNE20165390, KIDNE20169180,KIDNE20173430, KIDNE20189960, LIVER20026440, MESAN20006200,MESAN20021130, MESAN20033220, MESAN20056890, MESAN20057240,MESAN20065990, MESAN20067430, MESAN20069530, NESOP20004520,NT2NE20018890, NT2NE20026200, NT2NE20037050, NT2NE20053950,NT2NE20061030, NT2NE20111190, NT2NE20117580, NT2NE20119980,NT2NE20140130, NT2NE20141040, NT2RI20093010, NT2RP70003110,NT2RP70046410, NT2RP70075300, NTONG20032100, NTONG20034540,OCBBF20000740, OCBBF20012520, OCBBF20111600, OCBBF20120010,OCBBF20156450, OCBBF20157970, OCBBF20191950, PEBLM20001800,PEBLM20003260, PLACE60004260, PLACE60012620, PLACE60054230,PLACE60054870, PLACE60062660, PLACE60087680, PLACE60184870,PROST20015210, PROST20024250, PROST20036350, PROST20050390,PROST20058860, PROST20063430, PROST20065790, PROST20084720,PROST20099090, PROST20120070, PROST20127450, PROST20146590,PROST20152510, PROST20168600, PUAEN10000650, PUAEN20003120,SKMUS20008730, SKMUS20017400, SKMUS20040440, SKMUS20073590,SKMUS20079150, SKNSH20009710, SMINT20002320, SMINT20007470,SMINT20008110, SMINT20011950, SMINT20016150, SMINT20026200,SMINT20030740, SMINT20049920, SMINT20077960, SMINT20083290,SMINT20086250, SMINT20089600, SMINT20091190, SPLEN20023540,SPLEN20024190, SPLEN20042200, SPLEN20043680, SPLEN20055600,SPLEN20057830, SPLEN20059270, SPLEN20063890, SPLEN20073500,SPLEN20080070, SPLEN20085910, SPLEN20090880, SPLEN20098030,SPLEN20118050, SPLEN20136730, SPLEN20138600, SPLEN20139100,SPLEN20139360, SPLEN20180980, SPLEN20187490, SPLEN20193790,SPLEN20201830, TESTI10000190, TESTI20031310, TESTI20035790,TESTI20041630, TESTI20049060, TESTI20050720, TESTI20051200,TESTI20057430, TESTI20057590, TESTI20059080, TESTI20062120,TESTI20067480, TESTI20071630, TESTI20099350, TESTI20105130,TESTI20105910, TESTI20108060, TESTI20125920, TESTI20130530,TESTI20131440, TESTI20134680, TESTI20142540, TESTI20143180,TESTI20150420, TESTI20154370, TESTI20164210, TESTI20166670,TESTI20168880, TESTI20171070, TESTI20182760, TESTI20184750,TESTI20193080, TESTI20194880, TESTI20196970, TESTI20197600,TESTI20201760, TESTI20207170, TESTI20219110, TESTI20228740,TESTI20244430, TESTI20246480, TESTI20251740, TESTI20252690,TESTI20254030, TESTI20257910, TESTI20258720, TESTI20266050,TESTI20271790, TESTI20274960, TESTI20282530, TESTI20286590,THYMU10004280, THYMU20006020, THYMU20013250, THYMU20019260,THYMU20023560, THYMU20028150, THYMU20032820, THYMU20034400,THYMU20055460, THYMU20063650, THYMU20070250, THYMU20071120,THYMU20081110, THYMU20090230, THYMU20095920, THYMU20098350,THYMU20099060, THYMU20120730, THYMU20121040, THYMU20170080,THYMU20185650, THYMU20191970, TKIDN10000620, TKIDN10001920,TRACH20011540, TRACH20091070, TRACH20143710, TRACH20170860,UTERU10001060, UTERU20026620, UTERU20041630, UTERU20086530,UTERU20087070, UTERU20087850, UTERU20099510, UTERU20101150,UTERU20104310, UTERU20127030, UTERU20185220

The following 219 clones presumably belong to the category of enzymesand/or metabolism-related proteins. ADRGL20059610, ASTRO20026320,ASTRO20050810, ASTRO20088950, BNGH420008150, BNGH420035290,BNGH420074600, BRACE20050870, BRACE20097540, BRACE20200770,BRACE20204670, BRACE20215410, BRAMY20003540, BRAMY20005080,BRAMY20027990, BRAMY20028620, BRAMY20044920, BRAMY20055760,BRAMY20056620, BRAMY20072870, BRAMY20093490, BRAMY20096930,BRAMY20118490, BRAMY20125360, BRAMY20143870, BRAMY20152510,BRAMY20231150, BRAMY20244490, BRAMY20251210, BRAWH20021910,BRAWH20082920, BRAWH20093040, BRAWH20094900, BRAWH20183170,BRAWH20188750, BRAWH20190550, BRAWH20191980, BRCAN20005230,BRCOC20003600, CTONG20051100, CTONG20070910, CTONG20076810,CTONG20079590, CTONG20080140, CTONG20085210, CTONG20186290,DFNES20063460, DFNES20080880, FCBBF20023490, FCBBF20066340,FCBBF30004340, FCBBF30019140, FCBBF30022680, FCBBF30029250,FCBBF30072440, FCBBF30076310, FCBBF30085560, FCBBF30091520,FCBBF30107290, FCBBF30125880, FCBBF30132050, FCBBF30143550,FCBBF30153170, FCBBF30166220, FCBBF30171230, FCBBF30175350,FCBBF30236670, FCBBF30260480, FEBRA20038220, FEBRA20040560,FEBRA20078800, FEBRA20090160, FEBRA20172230, FEBRA20173330,HCHON20000870, HCHON20002710, HEART10001490, HEART20022200,HEART20047640, HEART20082570, HLUNG20011260, HLUNG20032460,HLUNG20041540, HLUNG20042730, HLUNG20054790, KIDNE20080690,KIDNE20083620, KIDNE20084040, KIDNE20147170, KIDNE20152440,KIDNE20173150, KIDNE20186170, KIDNE20189960, LIVER20011640,LIVER20026440, LIVER20055270, MESAN20021130, MESAN20033220,MESAN20038520, MESAN20057240, MESAN20058110, MESAN20065990,MESAN20095800, NT2NE20026200, NT2NE20042550, NT2NE20117580,NT2NE20127900, NT2RI20093010, NT2RP70064570, NTONG20034540,NTONG20043080, NTONG20053630, NTONG20053730, NTONG20058010,OCBBF20120010, OCBBF20167290, OCBBF20191950, PANCR10000860,PLACE60052940, PLACE60064180, PLACE60073090, PLACE60095600,PLACE60184410, PLACE60188630, PROST20007600, PROST20033240,PROST20036350, PROST20039300, PROST20050390, PROST20051310,PROST20052850, PROST20065790, PROST20075280, PROST20084720,PROST20099090, PROST20108850, PROST20152510, PUAEN20001520,PUAEN20002470, SKNMC20006350, SKNSH20057920, SMINT20008110,SMINT20049920, SMINT20094680, SPLEN20023540, SPLEN20024930,SPLEN20043680, SPLEN20048800, SPLEN20054500, SPLEN20057900,SPLEN20071820, SPLEN20080070, SPLEN20085910, SPLEN20108000,SPLEN20136730, SPLEN20180980, TESTI20012080, TESTI20030200,TESTI20031310, TESTI20038240, TESTI20050720, TESTI20051200,TESTI20059080, TESTI20062120, TESTI20066330, TESTI20076570,TESTI20103690, TESTI20105130, TESTI20106820, TESTI20108060,TESTI20112860, TESTI20121040, TESTI20130530, TESTI20131440,TESTI20168880, TESTI20170170, TESTI20196690, TESTI20196970,TESTI20199110, TESTI20205250, TESTI20212970, TESTI20222030,TESTI20226520, TESTI20227380, TESTI20244460, TESTI20244730,TESTI20250630, TESTI20260640, TESTI20262940, TESTI20264530,TESTI20285230, THYMU20006020, THYMU20013250, THYMU20034400,THYMU20039320, THYMU20055460, THYMU20055760, THYMU20063650,THYMU20066660, THYMU20070250, THYMU20087270, THYMU20096580,THYMU20100940, THYMU20110720, THYMU20120240, THYMU20120730,THYMU20170230, TRACH20011010, TRACH20021380, TRACH20091070,TRACH20113020, TRACH20143710, TRACH20164100, TRACH20190460,UTERU20087070, UTERU20089620, UTERU20104310, UTERU20185220,UTERU20188670

The following 44 clones presumably belong to the category of celldivision- and/or cell proliferation-related proteins. ASTRO20090680,BRACE20079370, BRAMY20234820, BRCAN10001050, BRCAN20005410,CTONG20032930, FCBBF20070950, FCBBF30002270, FCBBF30053300,FCBBF30105860, FCBBF30175350, FCBBF30215240, FCBBF30275590,FEBRA20045380, HLUNG20068120, KIDNE20134890, KIDNE20150730,MESAN20021470, NT2NE20077250, NT2NE20153620, NT2RP70030840,NTONG20053910, OCBBF20111370, OCBBF20174580, PROST20063430,SKNMC10001230, SMINT20028800, SPLEN20023540, SPLEN20057830,SPLEN20139360, TESTI20031410, TESTI20057840, TESTI20065650,TESTI20066650, TESTI20107320, TESTI20108060, TESTI20114480,TESTI20134680, TESTI20143180, TESTI20150920, TESTI20201760,TESTI20278280, TESTI20284260, THYMU20097920

The following 80 clones presumably belong to the category ofcytoskeleton-related proteins. ADRGL20062330, ASTRO20053430,BGGI120000670, BRACE20079370, BRAMY20038980, BRAMY20083330,BRAMY20094890, CTONG20004110, CTONG20032930, CTONG20077760,CTONG20083980, CTONG20169040, CTONG20183430, DFNES20018000,FCBBF30105860, FCBBF30130410, FCBBF30194550, FCBBF30201630,FCBBF30271990, FEBRA20005040, FEBRA20046200, FEBRA20099860,HCHON20015050, HLUNG20081530, KIDNE20081170, NT2RP70001730,NT2RP70003110, NTONG20032100, OCBBF20166890, OCBBF20174890,PLACE60054870, PLACE60055590, PLACE60071800, PLACE60118810,PROST20015210, PROST20097840, PROST20120070, PROST20146590,SKMUS20007260, SKMUS20008730, SKMUS20017400, SKMUS20073590,SMINT20062050, SMINT20074330, SMINT20077960, SPLEN20039180,SPLEN20049840, SPLEN20076470, SPLEN20182990, SPLEN20187490,SPLEN20195710, TESTI10000190, TESTI20041630, TESTI20057880,TESTI20058920, TESTI20060080, TESTI20064530, TESTI20064650,TESTI20065650, TESTI20067440, TESTI20071130, TESTI20099350,TESTI20112540, TESTI20125280, TESTI20136010, TESTI20153310,TESTI20175370, TESTI20222460, TESTI20244430, TESTI20254030,TESTI20258720, THYMU20024500,THYMU20062610, THYMU20098350,TRACH20043360, TRACH20098510, TRACH20149500, UTERU20089390,UTERU20122520, UTERU20168960

The following 70 clones presumably belong to the category of nuclearproteins and/or RNA synthesis-related proteins. ASTRO20026320,BRACE20050870, BRACE20200770, BRAMY20134050, BRAWH20063010,BRAWH20093040, BRAWH20174330, BRAWH20176850, CTONG20042640,FCBBF20023490, FCBBF20035490, FCBBF20070950, FCBBF30002270,FCBBF30048420, FCBBF30080730, FCBBF30115920, FCBBF30236670,FEBRA20035240, FEBRA20092760, FEBRA20173330, HHDPC20081230,HLUNG20011460, HLUNG20068120, KIDNE20089870, KIDNE20150730,MESAN20056890, MESAN20057240, NT2NE20037050, NT2NE20167660,NT2RP70031070, NTONG20053730, PLACE60064180, PLACE60095600,PROST20016760, PROST20051310, PROST20058860, PROST20152510,PUAEN20002470, SKMUS20079150, SKNSH20030640, SPLEN20023850,SPLEN20057830, SPLEN20139360, SPLEN20190430, TESTI20006830,TESTI20030200, TESTI20031410, TESTI20035790, TESTI20062120,TESTI20065650, TESTI20081890, TESTI20150920, TESTI20153310,TESTI20201760, TESTI20212970, TESTI20227380, TESTI20251740,TESTI20256560, TESTI20260640, TESTI20270130, TESTI20284260,TESTI20285230, THYMU20021090, THYMU20049060, THYMU20066660,THYMU20081110, THYMU20090230, THYMU20120240, UTERU10001060,UTERU20104310

The following 20 clones presumably belong to the category of proteinsynthesis- and/or protein transport-related proteins. BRAMY20038980,BRAMY20274510, CTONG20008190, CTONG20033610, FCBBF20018680,FEBRA20090220, KIDNE20141700, NT2NE20167660, NTONG20055200,PLACE60012620, PROST20036350, PROST20062820, SKMUS20040440,SMINT20000070, SPLEN20180980, TESTI20055680, TESTI20067440,TESTI20107240, THYMU20096580, THYMU20121040

The following 10 clones presumably belong to the category of cellulardefense-related proteins. ASTRO20089600, BRAMY20117670, FEBRA20087550,HLUNG20081390, MESAN20057240, NTONG20031580, PROST20007600,SPLEN20023850, SPLEN20043680, TESTI20261680

The following 19 clones presumably belong to the category of developmentand/or differentiation-related proteins. BRACE20061620, BRACE20200770,BRAMY20013670, CTONG20017490, CTONG20020950, HCHON10000150,MESAN20021470, OCBBF20165910, PROST20155370, PUAEN20002470,TESTI20079220, TESTI20079980, TESTI20166670, TESTI20184760,TESTI20252690, TRACH20040390, UTERU20089620, UTERU20094830,UTERU20169020

The following 168 clones presumably belong to the category of DNA-and/or RNA-binding proteins. ASTRO20038400, BGGI120010750,BNGH420070370, BRACE20003310, BRACE20061620, BRAMY20001510,BRAMY20040580, BRAMY20076100, BRAMY20111780, BRAMY20274510,BRAWH20040680, BRAWH20050740, BRAWH20063010, BRAWH20080580,BRAWH20095900, BRAWH20174330, BRSSN20066440, CTONG20020950,CTONG20044230, CTONG20053990, CTONG20072930, CTONG20074000,CTONG20165750, CTONG20186370, CTONG20186520, DFNES20046840,DFNES20073320, FCBBF20035430, FCBBF20070950, FCBBF30002270,FCBBF30003610, FCBBF30019140, FCBBF30021900, FCBBF30048420,FCBBF30080730, FCBBF30093170, FCBBF30114850, FCBBF30129010,FCBBF30136230, FCBBF30220050, FCBBF30228940, FCBBF30236670,FCBBF30263080, FCBBF30285930, FCBBF50003530, FEBRA20026820,FEBRA20027070, FEBRA20035240, FEBRA20046510, FEBRA20057010,FEBRA20063720, FEBRA20087550, FEBRA20092760, FEBRA20170240,FEBRA20177800, HCHON20002650, HEART20019310, HEART20063100,HHDPC20081230, HLUNG20011460, HLUNG20014590, HLUNG20028110,HLUNG20063700, HLUNG20068120, KIDNE20140870, LIVER20006260,MESAN20016270, MESAN20056890, MESAN20057240, NT2NE20038870,NT2NE20053950, NT2NE20060750, NT2NE20079670, NT2NE20082600,NT2NE20087270, NT2RP70029780, NT2RP70046410, NT2RP70057500,NT2RP70075300, NT2RP70090870, OCBBF20116250, OCBBF20120950,OCBBF20121910, OCBBF20156450, OCBBF20157970, OCBBF20166900,OCBBF20175360, OCBBF20177540, PEBLM10001470, PEBLM20003260,PLACE60066970, PLACE60122970, PLACE60177880, PROST20007170,PROST20024250, PROST20035170, PROST20051310, PROST20058860,PROST20151370, PROST20155370, PUAEN20003120, SMINT20011950,SMINT20030740, SMINT20039050, SMINT20044140, SMINT20086720,SPLEN20042200, SPLEN20043680, SPLEN20055600, SPLEN20059270,SPLEN20063250, SPLEN20139360, SPLEN20190430, TESTI10001570,TESTI20006830, TESTI20030200, TESTI20031410, TESTI20035790,TESTI20057430, TESTI20059810, TESTI20062120, TESTI20067480,TESTI20068790, TESTI20075240, TESTI20079220, TESTI20088840,TESTI20104090, TESTI20134970, TESTI20166670, TESTI20171070,TESTI20173960, TESTI20184760, TESTI20197600, TESTI20201760,TESTI20212970, TESTI20227380, TESTI20228740, TESTI20246480,TESTI20254030, TESTI20254990, TESTI20266050, TESTI20268240,TESTI20270130, TESTI20274960, TESTI20282530, TESTI20284260,TESTI20285230, THYMU10004280, THYMU20019260, THYMU20023560,THYMU20032820, THYMU20049060, THYMU20066660, THYMU20071120,THYMU20077250, THYMU20081110, THYMU20090230, TKIDN10001920,TRACH20108240, UTERU10001060, UTERU20026620, UTERU20041630,UTERU20094830, UTERU20099510, UTERU20101150, UTERU20169020,UTERU20177150, UTERU20188670

The following 93 clones presumably belong to the category of ATP- and/orGTP-binding proteins. ASTRO20026320, BNGH420035290, BRACE20050870,BRACE20079370, BRACE20200770, BRAMY20055760, BRAMY20118490,BRAMY20244490, BRAMY20251210, BRAWH20093040, BRAWH20190550,BRCAN10001050, BRCOC20003600, CTONG20008190, CTONG20030280,CTONG20032930, CTONG20176040, CTONG20184830, FCBBF20023490,FCBBF30019140, FCBBF30076310, FCBBF30105860, FCBBF30175350,FCBBF30201630, FCBBF30236670, FEBRA20005040, FEBRA20090160,FEBRA20173330, HCHON20000870, HLUNG20011260, HLUNG20052300,KIDNE20081170, KIDNE20134890, LIVER20030650, LIVER20055270,MESAN20065990, NT2NE20042550, NTONG20043080, NTONG20055200,OCBBF20182060, PLACE60054870, PLACE60064180, PLACE60095600,PLACE60140640, PROST20015210, PROST20033240, PROST20036350,PROST20051310, PROST20052850, PROST20062820, PROST20075280,PROST20120070, PUAEN20002470, SKNSH20052400, SKNSH20057920,SMINT20008110, SPLEN20023850, SPLEN20043680, SPLEN20049840,SPLEN20136730, SPLEN20180980, SPLEN20193790, TESTI20055680,TESTI20058920, TESTI20060080, TESTI20064650, TESTI20071130,TESTI20099350, TESTI20106820, TESTI20112860, TESTI20134680,TESTI20136010, TESTI20143180, TESTI20175370, TESTI20212970,TESTI20222460, TESTI20227380, TESTI20244220, TESTI20244460,TESTI20264530, THYMU20013250, THYMU20039320, THYMU20062610,THYMU20066660, THYMU20087270, THYMU20096580, THYMU20100940,THYMU20176010, TRACH20043360, TRACH20098510, TRACH20113020,UTERU20185220, UTERU20188670

Among the clones other than the ones shown above, BNGH420036410,FCBBF30257370 are clones which were predicted to highly possibly belongto the category of secretory protein and/or membrane protein based onthe result of domain search by Pfam.

SMINT20044730, TESTI20140970

The two clones shown above are clones which were predicted to highlypossibly belong to the category of glycoprotein-related protein based onthe result of domain search by Pfam. BRACE20055560, CTONG20046690,DFNES20043710, FCBBF30005500, MESAN20030350, MESAN20030370,PLACE60074820, TESTI20058350, TESTI20106170, TRACH20131230,UTERU20000950

The 11 clones shown above are clones which were predicted to highlypossibly belong to the category of signal transduction-related proteinbased on the result of domain search by Pfam. ASTRO20010290,BRACE20099070, CTONG20007660, DFNES20076340, DFNES20094820,FCBBF30125460, FCBBF30142290, FCBBF30169280, FEBRA20031000,NT2NE20026510, NT2RP70031340, PLACE50001390, SPLEN20135030,TESTI20046890, TESTI20060350, TESTI20166290, TESTI20259110,THYMU20184550

The 18 clones shown above are clones which were predicted to highlypossibly belong to the category of transcription-related protein basedon the result of domain search by Pfam. ADRGL20047770, ADRGL20079060,BRACE20014450, BRACE20051600, BRAWH20185260, CTONG20033750,CTONG20070090, CTONG20190290, FCBBF20020440, FCBBF30005360,FCBBF30173960, FEBRA20031000, KIDNE20087880, LIVER20013890,MESAN20030350, MESAN20030370, OCBBF20113110, PLACE60074820,PLACE60093380, PROST20028970, PROST20102190, SALGL10001070,SPLEN20006950, SPLEN20011350, SPLEN20050090, TESTI20060830,TESTI20066150, TESTI20120900, TESTI20132310, TESTI20148380,TESTI20162980, TESTI20166290, TESTI20205100, THYMU20112590,TRACH20029880

The 35 clones shown above are clones which were predicted to highlypossibly belong to the category of enzyme and/or metabolism-relatedprotein based on the result of domain search by Pfam.

PLACE60054820, TESTI20197030

The two clones shown above are clones which were predicted to highlypossibly belong to the category of cell division and/or cellproliferation-related protein based on the result of domain search byPfam.

ASTRO20006530, OCBBF20016390, TRACH20058000

The three clones shown above are clones which were predicted to highlypossibly belong to the category of cytoskeleton-related protein based onthe result of domain search by Pfam.

BRACE20065470, PLACE60054820

The two clones shown above are clones which were predicted to highlypossibly belong to the category of nuclear protein and/or RNAsynthesis-related protein based on the result of domain search by Pfam.ASTRO20010290, BRACE20099070, BRAWH20014590, CTONG20007660,DFNES20076340, DFNES20094820, FCBBF30125460, FCBBF30142290,FCBBF30169280, FEBRA20031000, MESAN20034440, NT2NE20026510,NT2RP70031340, PLACE50001390, SPLEN20135030, TESTI20046890,TESTI20060350, TESTI20166290, TESTI20259110, THYMU20104480,THYMU20184550

The 21 clones shown above are clones which were predicted to highlypossibly belong to the category of DNA- and/or RNA-binding protein basedon the result of domain search by Pfam.

KIDNE20133880, MESAN20030350, MESAN20030370, TESTI20059480

The four clones shown above are clones which were predicted to highlypossibly belong to the category of ATP- and/or GTP-binding proteinsbased on the result of domain search by Pfam.

The 205 clones shown below are clones which were unassignable to any ofthe above-mentioned categories, but have been predicted to have somefunctions based on homology search using their full-length nucleotidesequences and motif search in their estimated ORFs. Clone Name,Definition in the result of homology search or Motif Name in the motifsearch, demarcated by a double slash mark (//), are shown below.

-   ADRGL20022600//DIAPHANOUS PROTEIN HOMOLOG 1 (P140MDIA).-   ADRGL20023920//ABC1 PROTEIN HOMOLOG PRECURSOR.-   ASTRO20001910//Rattus norvegicus mRNA for annexin V-binding protein    (ABP-10), partial cds.-   ASTRO20009140//PUTATIVE COMPETENCE-DAMAGE PROTEIN.-   ASTRO20046280//PSU1 PROTEIN.-   ASTRO20058960//DNA damage inducible protein homolog—fission yeast    (Schizosaccharomyces pombe)-   BNGH420024870//C2 domain//C2 domain//C2 domain-   BRACE20007330//RING CANAL PROTEIN (KELCH PROTEIN).-   BRACE20052430//Homo sapiens AMSH mRNA, complete cds.-   BRACE20054600//Xenopus laevis mRNA for Kielin, complete cds.-   BRACE20059810//TSC-22/dip/bun family-   BRACE20063540//MEROZOITE SURFACE PROTEIN CMZ-8 (FRAGMENT).-   BRACE20079200//Xenopus laevis mRNA for Kielin, complete cds.-   BRAMY20016780//Proprotein convertase P-domain-   BRAMY20023640//UBX domain-   BRAMY20045420//Domain found in Dishevelled, Egl-10, and Pleckstrin-   BRAMY20056840//UBE-1c2-   BRAMY20063750//Homo sapiens HRIHFB2007 mRNA, partial cds.-   BRAMY20102900//Homo sapiens RU1 (RU1) mRNA, complete cds.-   BRAMY20158550//CALMODULIN.-   BRAMY20223010//Mus musculus leucine-rich glioma-inactivated 1    protein precursor, (Lgi1) mRNA, complete cds.-   BRAMY20238630//TETRATRICOPEPTIDE REPEAT PROTEIN 4.-   BRAMY20245760//Araneus diadematus fibroin-4 mRNA, partial cds.-   BRAWH20047790//HMG (high mobility group) box-   BRSSN20005610//Mus musculus semaphorin cytoplasmic domain-associated    protein 3A (Semcap3) mRNA, complete cds.-   BRSSN20005660//Bacterial type II secretion system protein-   BRSSN20093890//Homo sapiens mRNA for Kelch motif containing protein,    complete cds.-   CTONG20041150//Streptomyces ansochromogenes strain 7100 SanE (sanE)    gene, complete cds.-   CTONG20066110//Homo sapiens DEME-6 mRNA, partial cds.-   CTONG20069420//Ribosomal protein S14p/S29e-   CTONG20071040//BETA CRYSTALLIN B2 (BP).-   CTONG20074170//DENN (AEX-3) domain-   CTONG20083430//Nuclear transition protein 2-   CTONG20170940//MYOTROPHIN (V-1 PROTEIN) (GRANULE CELL    DIFFERENTIATION PROTEIN).-   CTONG20174290//TRICHOHYALIN.-   CTONG20174580//Homo sapiens mRNA for vascular Rab-GAP/TBC-containing    protein complete cds.-   CTONG20180690//Collagen triple helix repeat (20 copies)-   CTONG20186550//cca3 protein—rat-   CTONG20188080//TPR Domain-   FCBBF10004760//Homo sapiens GAP-like protein (N61) mRNA, complete    cds.-   FCBBF20033360//RING CANAL PROTEIN (KELCH PROTEIN).-   FCBBF20041380//SAM domain (Sterile alpha motif)-   FCBBF20043730//UBA domain-   FCBBF20056580//Mus musculus NSD1 protein mRNA, complete cds.-   FCBBF20059660//TPR Domain-   FCBBF30019180//SERINE/THREONINE PROTEIN PHOSPHATASE 2A, 65 KDA    REGULATORY SUBUNIT A, ALPHA ISOFORM (PP2A, SUBUNIT A, PR65-ALPHA    ISOFORM) (PP2A, SUBUNIT A, R1-ALPHA ISOFORM).-   FCBBF30026580//Homo sapiens retinoblastoma-associated protein RAP140    mRNA, complete cds.-   FCBBF30035570//C2 domain-   FCBBF30079770//D-isomer specific 2-hydroxyacid dehydrogenases-   FCBBF30100120//Mus musculus semaphorin cytoplasmic domain-associated    protein 3A (Semcap3) mRNA, complete cds.-   FCBBF30100410//Mus musculus testis-specific Y-encoded-like protein    (Tspyl1) mRNA, complete cds.-   FCBBF30118890//Drosophila melanogaster La related protein (larp)    mRNA, partial cds.-   FCBBF30138000//trg protein—rat-   FCBBF30157270//Rattus norvegicus PAPIN mRNA, complete cds.-   FCBBF30161780//gag gene protein p24 (core nucleocapsid    protein)//Zinc knuckle-   FCBBF30198670//dof protein—fruit fly (Drosophila melanogaster)-   FCBBF30222910//Mus musculus Rap2 interacting protein 8 (RPIP8) mRNA,    complete cds.-   FCBBF30255680//Rattus norvegicus brain specific cortactin-binding    protein CBP90 mRNA, partial cds.-   FCBBF30260210//Drosophila melanogaster KISMET-L long isoform (kis)    mRNA, complete cds.-   FCBBF30282020//cca3 protein—rat-   FCBBF40000610//late gestation lung 2 protein [Rattus norvegicus].-   FEBRA20029620//Leucine Rich Repeat//Leucine Rich Repeat//Leucine    Rich Repeat-   FEBRA20031150//Homo sapiens HSKM-B (HSKM-B) mRNA, complete cds.-   FEBRA20038330//Corticotropin-releasing factor family-   FEBRA20038970//Homo sapiens mRNA for stabilin-1 (stab1 gene).-   FEBRA20088610//CELLULAR RETINALDEHYDE-BINDING PROTEIN (CRALBP).-   FEBRA20150420//HYPOTHETICAL 131.5 KDA PROTEIN C02F12.7 IN CHROMOSOME    X.-   FEBRA20175330//D-isomer specific 2-hydroxyacid dehydrogenases-   HEART10001420//Mus musculus skm-BOP1 (Bop) mRNA, complete cds.-   HLUNG20024050//Rubredoxin-   HLUNG20030420//Mus musculus mRNA for MAIL, complete cds.-   HLUNG20030490//Ambystoma tigrinum RPE65 protein mRNA, complete cds.-   HLUNG20033060//Homo sapiens GAP-like protein (N61) mRNA, complete    cds.-   HLUNG20041590//ubiquitous tetratricopeptide containing protein RoXaN    [Homo sapiens].-   HLUNG20045340//MOB2 PROTEIN (MPS1 BINDER 2).-   HLUNG20051330//FHIPEP family-   HLUNG20070410//Dihydropyridine sensitive L-type calcium channel    (Beta subunit)-   HLUNG20072100//Gallus gallus Dach2 protein (Dach2) mRNA, complete    cds.-   HLUNG20083480//Chicken mRNA for TSC-22 variant, complete cds, clone    SLFEST52.-   KIDNE20027980//SAM domain (Sterile alpha motif)-   KIDNE20084730//Homo sapiens FH1/FH2 domain-containing protein FHOS    (FHOS) mRNA, complete cds.-   KIDNE20149780//NG28 [Mus musculus]-   KIDNE20154330//Rattus norvegicus mRNA for multi PDZ domain protein.-   KIDNE20170400//Leucine Rich Repeat//Leucine Rich Repeat//Leucine    Rich Repeat//Protein kinase C terminal domain//Rubredoxin-   KIDNE20189890//Homo sapiens mRNA for KARP-1-binding protein 2    (KAB2), complete cds.-   LIVER20010760//Homo sapiens C-type lectin-like receptor-1 mRNA,    complete cds.-   LIVER20040740//RETINAL-BINDING PROTEIN (RALBP).-   MESAN20009090//Homo sapiens CEGP1 protein (CEGP1), mRNA-   MESAN20026870//PAN domain//TBC domain-   MESAN20090190//CEGP1 protein [Homo sapiens].-   NT2NE20059680//Homo sapiens integrin cytoplasmic domain associated    protein (Icap-1a) mRNA, complete cds.-   NT2NE20077270//Adenovirus EB1 55K protein/large t-antigen-   NT2NE20087850//ANTER-SPECIFIC PROLINE-RICH PROTEIN APG (PROTEIN CEX)    (FRAGMENT).-   NT2NE20095230//Homo sapiens HSKM-B (HSKM-B) mRNA, complete cds.-   NT2NE20108420//KES1 PROTEIN.-   NT2NE20173970//Rattus norvegicus beta-catenin binding protein mRNA,    complete cds.-   NT2NE20177210//Leishmania major partial ppg1 gene for    proteophosphoglycan.-   NT2RP70012830//CALPHOTIN.-   NT2RP70035110//Caenorhabditis elegans UNC-89 (unc-89) gene, complete    cds.-   NTONG20002230//Mus musculus RW1 protein mRNA, complete cds.-   NTONG20005310//Ribosomal protein S9/S16-   NTONG20029850//CALCYPHOSINE (R2D5 ANTIGEN).-   NTONG20035150//RING CANAL PROTEIN (KELCH PROTEIN).-   NTONG20058220//Homo sapiens phosphoprotein pp75 mRNA, partial cds.-   OCBBF20005220//Rattus norvegicus Fos-related antigen mRNA, complete    cds.-   OCBBF20011860//Mus musculus epithelial protein lost in neoplasm-a    (Eplin) mRNA, complete cds.-   OCBBF20016810//enhancer of polycomb [Mus musculus]-   OCBBF20147070//DNA polymerase (viral) C-terminal domain-   OCBBF20160380//liver stage antigen LSA-1—Plasmodium falciparum-   OCBBF20177910//Corticotropin-releasing factor family-   PEBLM20005020//Virion host shutoff protein-   PLACE60055460//Homo sapiens leucine-zipper protein FKSG13 (FKSG13)    mRNA, complete cds.-   PLACE60068710//SUPPRESSOR PROTEIN SRP40.-   PLACE60080360//mucin [Homo sapiens]-   PLACE60082850//Pathogenesis-related protein Bet v I family-   PLACE60098350//Human hepatocellular carcinoma associated protein    (JCL-1) mRNA, complete cds.-   PLACE60105680//Homo sapiens mRNA for TU12B1-TY, complete cds.-   PLACE60119700//Homo sapiens mRNA for ABP32, complete cds.-   PLACE60120280//SER/THR-RICH PROTEIN T10 IN DGCR REGION.-   PLACE60132200//TRICHOHYALIN.-   PLACE60181870//Pentaxin family-   PROST20084470//Plasmodium berghei strain NYU2 merozoite surface    protein-1 mRNA, partial cds.-   PROST20087240//gag gene protein p24 (core nucleocapsid protein)-   PROST20122490//Gallus gallus syndesmos mRNA, complete cds.-   PROST20130320//S-100/ICaBP type calcium binding domain-   PROST20152870//Homo sapiens APC2 gene, exon 14.-   PUAEN10001640//Mus musculus cerebellar postnatal development    protein-1 (Cpd1) mRNA, partial cds.-   PUAEN20000800//Bleomycin resistance protein-   SMINT20012220//Collagen triple helix repeat (20 copies)-   SMINT20035510//Drosophila melanogaster La related protein (larp)    mRNA, partial cds.-   SMINT20036440//Drosophila melanogaster epsin-like protein mRNA,    complete cds.-   SMINT20038660//Homo sapiens HNOEL-iso (HNOEL-iso) mRNA, complete    cds.-   SMINT20043390//Ras association (RalGDS/AF-6) domain-   SMINT20048720//Cytochrome P450//Cytochrome P450-   SMINT20052130//Rattus norvegicus mRNA for gankyrin homologue,    complete cds.-   SMINT20054050//ABC1 PROTEIN HOMOLOG PRECURSOR.-   SPLEN20024770//Rattus norvegicus (rsec6) mRNA, complete cds.-   SPLEN20040780//CORNIFIN B (SMALL PROLINE-RICH PROTEIN 1B) (SPR1B)    (SPR1 B).-   SPLEN20041810//BC-2 protein [Homo sapiens]-   SPLEN20100040//258.1 KDA PROTEIN C210RF5 (KIAA0933).-   SPLEN20104150//Ribosomal protein L36-   SPLEN20116720//Homo sapiens misato mRNA, partial cds.-   SPLEN20176130//Homo sapiens mRNA for ALEX1, complete cds.-   SPLEN20181570//TRICHOHYALIN.-   TESTI20004310//TRICHOHYALIN.-   TESTI20016970//TPR Domain-   TESTI20030440//TRICHOHYALIN.-   TESTI20043180//mouse mRNA for megakaryocyte potentiating factor,    complete cds.-   TESTI20043910//IQ calmodulin-binding motif//IQ calmodulin-binding    motif//IQ calmodulin-binding motif//IQ calmodulin-binding motif//IQ    calmodulin-binding motif-   TESTI20044900//Strongylocentrotus purpuratus radial spokehead mRNA,    complete cds.-   TESTI20046110//Extracellular link domain-   TESTI20047930//Homo sapiens NY-REN-2 antigen mRNA, complete cds.-   TESTI20049410//Proprotein convertase P-domain-   TESTI20053950//IQ calmodulin-binding motif-   TESTI20054700//Streptococcus pneumoniae strain g375 surface protein    PspC (pspC) gene, pspC-8.1 allele, complete cds.-   TESTI20055880//Serum amyloid A protein-   TESTI20056030//Homo sapiens 88-kDa Golgi protein (GM88) mRNA,    complete cds.-   TESTI20061090//Keratin, high sulfur B2 protein-   TESTI20064370//TPR Domain//TPR Domain//TPR Domain//TPR    Domain//Synaptobrevin-   TESTI20084250//OXYSTEROL-BINDING PROTEIN.-   TESTI20092170//ENV polyprotein (coat polyprotein)-   TESTI20116050//UBX domain-   TESTI20120500//Kelch motif//Kelch motif-   TESTI20126280//Mus musculus STAP mRNA for sperm tail associated    protein, complete cds.-   TESTI20144390//TESTIS-SPECIFIC PROTEIN PBS13.-   TESTI20165990//Ribosomal protein L36-   TESTI20169500//HYPOTHETICAL 51.9 KDA PROTEIN C27F1.04C IN CHROMOSOME    I.-   TESTI20170280//Flagellar L-ring protein-   TESTI20176450//thioredoxin interacting factor [Mus musculus].-   TESTI20179230//Dihydropyridine sensitive L-type calcium channel    (Beta subunit)-   TESTI20180600//Homo sapiens HOM-TES-85 tumor antigen mRNA, complete    cds.-   TESTI20209050//HYPOTHETICAL 113.1 KDA PROTEIN IN PRE5-FET4    INTERGENIC REGION.-   TESTI20210570//RETINAL-BINDING PROTEIN (RALBP).-   TESTI20215310//Homo sapiens calcyclin binding protein mRNA, complete    cds.-   TESTI20247440//Human BLu protein testis isoform (BLu) mRNA, complete    cds.-   TESTI20249360//Homo sapiens DEME-6 mRNA, partial cds.-   TESTI20250220//TRICHOHYALIN.-   TESTI20251440//Rattus norvegicus (rsec6) mRNA, complete cds.-   TESTI20255460//Mus musculus mRNA for MIWI (piwi), complete cds.-   THYMU20009500//TPR Domain-   THYMU20010180//MOB1 PROTEIN (MPS1 BINDER 1).-   THYMU20013810//Human SEC7 homolog Tic (TIC) mRNA, complete cds.-   THYMU20018250//TPR Domain-   THYMU20026950//Mus musculus ROSA 26 transcription AS ROSA26AS mRNA,    complete cds.-   THYMU20028410//Mus musculus Pax transcription activation domain    interacting protein PTIP mRNA, complete cds.-   THYMU20030460//Homo sapiens tumor endothelial marker 7 precursor    (TEM7) mRNA, complete cds.-   THYMU20031330//Homo sapiens putative nucleotide binding protein    mRNA, complete cds.-   THYMU20052460//PHORBOLIN I (FRAGMENTS).-   THYMU20055450//Zona pellucida-like domain-   THYMU20083830//Homo sapiens angiostatin binding protein 1 mRNA,    complete cds.-   THYMU20139160//Uncharacterized protein family UPF0031-   THYMU20151610//Homo sapiens antigen NY-CO-1 (NY-CO-1) mRNA, complete    cds.-   TRACH20093400//TRICHOHYALIN.-   TRACH20104510//Uncharacterized protein family UPF0005-   TRACH20122980//HYPOTHETICAL PROTEIN MJ0798.-   TRACH20139280//PX domain-   TRACH20164810//D-isomer specific 2-hydroxyacid dehydrogenases-   TRACH20165540//Human alpha-1 type I collagen gene surrounding    osteogenesis imperfecta OI type II deletion.-   UTERU20051790//guanylate kinase-interacting protein 1 Maguin-1,    membrane-associated—rat-   UTERU20083020//Domain of unknown function DUF71-   UTERU20121140//Rhodanese-like domain-   UTERU20128560//26.4 KDA PROTEIN IN RUVC-ASPS INTERGENIC REGION.-   UTERU20132620//AXONEME-ASSOCIATED PROTEIN MST101(2).-   UTERU20134830//pellino (Drosophila) homolog 2 [Homo sapiens]-   UTERU20181270//Zinc knuckle

Further, the reason is that a polypeptide does not always belong solelyto a single category of the above-described functional categories, andtherefore, a polypeptide may belong to any of the predicted functionalcategories. Besides, additional functions can be found for the clonesclassified into these functional categories by further analyses.

Since the polypeptide encoded by clones of the invention containsfull-length amino acid sequence, it is possible to analyze itsbiological activity, and its effect on cellular conditions such as cellproliferation and differentiation by expressing the polypeptide as arecombinant polypeptide using an appropriate expression system,injecting the recombinant into the cell, or raising a specific antibodyagainst the polypeptide.

The biological activities of respective polypeptides can be analyzed bythe methods as shown below. Secretory protein, transmembrane protein:

-   -   ‘Ion Channels’ (Ed., R. H. Ashley, 1995) of “The Practical        Approach Series” (IRL PRESS),    -   “Growth Factors” (Eds., I. McKay, I. Leigh, 1993),    -   “Extracellular Matrix” (Eds., M. A. Haralson, J. R. Hassell,        1995);        Glycoprotein-Related Protein:    -   “Glycobiology” (Eds., M. Fukuda, A. Kobata, 1993) of “The        Practical Approach Series” (IRL PRESS),    -   “Glycoprotein Analysis in Biomedicine” (Ed., Elizabeth F.        Hounsell, 1993) of “Method in Molecular Biology” (Humana Press)        series;        Signal Transduction-Related Protein:    -   “Signal Transduction” (Ed., G. Milligan, 1992) of “The Practical        Approach Series” (IRL PRESS),    -   “Protein Phosphorylation” (Ed., D. G. Hardie, 1993), or    -   “Signal Transduction Protocols” (Eds., David A. Kendall,        Stephen J. Hill, 1995) of “Method in Molecular Biology” (Humana        Press) series;        Transcription-Related Protein:    -   “Gene Transcription” (Eds., B. D. Hames, S. J. Higgins, 1993) of        “The Practical Approach Series” (IRL PRESS),    -   “Transcription Factors” (Ed., D. S. Latchman, 1993);        Enzyme and/or Metabolism-Related Protein:    -   “Enzyme Assays” (Eds., ROBERT EISENTHAL and MICHAEL J.        DANSON, 1992) of “The Practical Approach Series” (IRL PRESS);        Cell Division and/or Cell Proliferation-Related Protein:    -   “Cell Growth, Differentiation and Senescence” (Ed., GEORGE        STUDZINSKI, 2000) of “The Practical Approach Series” (IRL        PRESS);        Cytoskeleton-Related Protein:    -   “Cytoskeleton: Signalling and Cell Regulation” (Eds., KERMIT L.        CARRAWAY and CAROLIE A. CAROTHERS CARRAWAY, 2000) of “The        Practical Approach Series” (IRL PRESS),    -   “Cytoskeleton Methods and Protocols” (Ed., Gavin, Ray H., 2000)        of “Method in Molecular Biology” (Humana Press) series;        Nuclear Protein and/or RNA Synthesis-Related Protein:    -   “Nuclear Receptors” (Ed., DIDIER PICARD, 1999) of “The Practical        Approach Series” (IRL PRESS),    -   “RNA Processing” (Eds., STEPHEN J. HIGGINS and B. DAVID HAMES,        1994);        Protein Synthesis and/or Transport-Related Protein:    -   “Membrane Transport” (Ed., STEPHEN A. BALDWIN, 2000) of “The        Practical Approach Series” (IRL PRESS),    -   “Protein Synthesis Methods and Protocols” (Eds., Martin,        Robin, 1998) of “Method in Molecular Biology” (Humana Press)        series;        Cellular Defense-Related Protein:    -   “DNA Repair Protocols” (Henderson, Daryl S., 1999) of “Method in        Molecular Biology” (Humana Press) series,    -   “Chaperonin Protocols” (Eds., Schneider, Christine, 2000);        Development and/or Differentiation-Related Protein:    -   “Developmental Biology Protocols” (Eds., ROBERT EISENTHAL and        MICHAEL J. DANSON, 1992) of “Method in Molecular Biology”        (Humana Press) series;        DNA- and/or RNA-Binding Protein:    -   “DNA-Protein Interactions Principles and Protocols” (Eds.,        Kneale, G. Geoff, 1994) of “Method in Molecular Biology” (Humana        Press) series,    -   “RNA-Protein Interaction Protocols” (Eds., Haynes, Susan R.,        1999);        ATP- and/or GTP-Binding Protein:    -   “Signal Transduction Protocols” (Eds., David A. Kendall,        Stephen J. Hill, 1995) of “Method in Molecular Biology” (Humana        Press) series.

In the categorization, the clone predicted to belong to the category ofsecretory and/or membrane protein means a clone having hit data withsome annotation, such as growth factor, cytokine, hormone, signal,transmembrane, membrane, extracellular matrix, receptor, G-proteincoupled receptor, ionic channel, voltage-gated channel, calcium channel,cell adhesion, collagen, connective tissue, etc., suggesting that it wasa secretory or membrane protein, or a clone in which the presence ofnucleotide sequence encoding a signal sequence or transmembrane regionwas suggested by the results of PSORT and SOSUI analyses for deducedORF.

The clone predicted to belong to the category of glycoprotein-relatedprotein means a clone having hit data with some annotation, such asglycoprotein, suggesting that the clone encodes a glycoprotein-relatedprotein.

The clone predicted to belong to the category of signaltransduction-related protein means a clone having hit data with someannotation, such as serine/threonine-protein kinase, tyrosine-proteinkinase, SH3 domain, SH2 domain, etc., suggesting that the clone encodesa signal transduction-related protein.

The clone predicted to belong to the category of transcription-relatedprotein means a clone having hit data with some annotation, such astranscription regulation, zinc finger, homeobox, etc., suggesting thatthe clone encodes a transcription-related protein.

The clone predicted to belong to the category of disease-related proteinmeans a clone having hit data with some annotation, such as diseasemutation, syndrome, etc., suggesting that the clone encodes adisease-related protein, or a clone whose full-length nucleotidesequence has hit data for Swiss-Prot, GenBank, UniGene, or nr, where thehit data corresponds to genes or polypeptides which have been depositedin the Online Mendelian Inheritance in Man (OMIM)(http://www.ncbi.nlm.nih.gov/Omim/), which is the human gene and diseasedatabase described later.

The clone predicted to belong to the category of enzyme and/ormetabolism-related protein means a clone having hit data with someannotation, such as metabolism, oxidoreductase, E. C. No. (Enzymecommission number), etc., suggesting that the clone encodes an enzymeand/or metabolism-related protein.

The clone predicted to belong to the category of cell division and/orcell proliferation-related protein means a clone having hit data withsome annotation, such as cell division, cell cycle, mitosis, chromosomalprotein, cell growth, apoptosis, etc., suggesting that the clone encodesa cell division and/or cell proliferation-related protein.

The clone predicted to belong to the category of cytoskeleton-relatedprotein means a clone having hit data with some annotation, such asstructural protein, cytoskeleton, actin-binding, microtubles, etc.,suggesting that the clone encodes a cytoskeleton-related protein.

The clone predicted to belong to the category of nuclear protein and/orRNA synthesis-related protein means a clone having hit data with someannotation, such as nuclear protein, RNA splicing, RNA processing, RNAhelicase, polyadenylation, etc., suggesting that the clone encodes anuclear protein and/or RNA synthesis-related protein.

The clone predicted to belong to the category of protein synthesisand/or transport-related protein means a clone having hit data with someannotation, such as translation regulation, protein biosynthesis,amino-acid biosynthesis, ribosomal protein, protein transport, signalrecognition particle, etc., suggesting that the clone encodes a proteinsynthesis and/or transport-related protein.

The clone predicted to belong to the category of cellulardefense-related protein means a clone having hit data with someannotation, such as heat shock, DNA repair, DNA damage, etc., suggestingthat the clone encodes a cellular defense-related protein.

The clone predicted to belong to the category of development and/ordifferentiation-related proteins means a clone having hit data with someannotation, such as developmental protein, etc., suggesting that theclone encodes a development and/or differentiation-related protein.

The clone predicted to belong to the category of DNA- and/or RNA-bindingprotein means a clone having hit data with some annotation, such asDNA-binding, RNA-binding, etc.

The clone predicted to belong to the category of ATP-and/or GTP-bindingprotein means a clone having hit data with some annotation, such asATP-binding, GTP-binding, etc.

As to a protein involved in a disease, it is possible to perform afunctional analysis as described above, but also possible to analyzecorrelation between the expression or the activity of the protein and acertain disease by using a specific antibody that is obtained by usingexpressed protein. Alternatively, it is possible to utilize the databaseOMIM, which is a database of human genes and diseases, to analyze theprotein. Further, new information is constantly being deposited in theOMIM database. Therefore, it is possible for one skilled in the art tofind a new relationship between a particular disease and a gene of thepresent invention in the most up-to-date database. The proteins involvedin diseases are useful for developing a diagnostic marker or medicinesfor regulation of their expression and activity, or as a target of genetherapy.

Also, as for a secretory protein, membrane protein, signaltransduction-related protein, glycoprotein-related protein, ortranscription-related protein, etc., search of the OMIM with thefollowing keywords resulted in the finding that the proteins areinvolved in many diseases (the result of the OMIM search for secrete andmembrane proteins is shown below). Also, association between proteinsrelated to signal transduction or transcription and diseases is reportedin “Transcription Factor Research-1999” (Fujii, Tamura, Morohashi,Kageyama, and Satake edit, (1999) Jikken-Igaku Zoukan, Vol. 17, No. 3),and “Gene Medicine”, (1999) Vol. 3, No. 2). When cancer is used as anexample, as described in “Biology of Cancer” (S. Matsubara, 1992) ofLife Science series (Shokabo), many proteins are involved in cancers,which include enzyme and/or metabolism-related proteins,cytoskeleton-related proteins, cell division and/or cellproliferation-related proteins as well as secretory proteins, membraneproteins, signal transduction-related proteins, glycoprotein-relatedproteins, transcription-related proteins. As clearly seen by the aboveexample, it is evident that not only disease-related proteins but alsosecretory proteins, membrane proteins, signal transduction-relatedproteins, glycoprotein-related proteins, transcription-related proteins,etc. are often involved in diseases, and thus they can be useful targetsin the field of medical industry.

The result of the OMIM search for secretory and membrane proteins isshown below, in which the keywords,

-   -   (1) secretion protein,    -   (2) membrane protein,    -   (3) channel, and    -   (4) extracellular matrix were used.

Shown in the search result are only the accession numbers in the OMIM.Using the number, data showing the relationship between a disease and agene or protein can be seen. The OMIM data has been renewed everyday.

1) Secretion Protein

354 entries found, searching for “secretion protein” *604667, *104760,*176860, *151675, *139320, *107400, *604029, *118910, #200100, *176880,*603850, *147572, *604028, *179513, *125950, *139250, *246700, *600946,*600560, *602926, 185860, *605083, *603215, *602421, *157147, *179512,*600174, *109270, *604710, *138120, *179510, *600998, *179509, *170280,*179511, *600626, *603831, *601489, *154545, *179490, *603826, *122559,*603216, *102720, *147290, *164160, *603062, *112262, *602672, *605435,*605322, *131230, *601652, *603166, *601746, *601591, *179508, #160900,*104311, *600759, *147545, *167805, #104300, *167770, #219700, *168470,*601684, *602049, *601146, *605227, *602434, *602534, *114840, *603489,*604323, *107470, *600753, *600768, *118825, *600564, *604252, *173120,*134370, *192340, *308230, *600322, *605359, *600046, *300090, 106160,*600041, #262500, *605563, *150390, *158106, *182590, #103580, *104610,#173900, *134797, *143890, #145980, *306900, *308700, *176300, *227500,*137350, #154700, *138079, *600760, *107730, *142410, *147670, *124092,*590050, *152760, *600509, *605646, *201910, *227600, *152790, *300200,*300300, 300800, *138160, *107741, *120150, *601199, *120180, *120160,*176730, *133170, *122560, *107300, *137241, *120140, *101000, *193400,*217000, *272800, *600937, #201710, *600377, #174800, *106100, #274600,*173350, #177170, *147620, *214500, *131244, *202110, *120120, *601007,*191160, *147470, *603372, *600733, *252800, *190160, *138040, *158070,*162151, #125700, #130070, *113811, *603355, *171060, *136435, #184700,*603732, *190180, *164008, *186590, *120220, *604312, *152200, *138130,*605085, *605353, *600840, #166210, *188545, *207750, *173360, *601933,#194050, *153450, *138850, *253200, *307030, *157145, *600514, *600262,*264080, *147380, *600281, #204000, #227810, *232200, *188826, *232800,*161561, #166200, *188400, *153620, *182099, *218040, #265800, *172400,#177200, *176805, #211600, #214700, #176410, *152780, *600633, *601771,*301500, *605402, *601922, *307800, *147892, *147720, *312060, #520000,*147660, *106150, *602358, *107270, *601769, *147440, *604558, *131530,*600270, *601610, *603692, *603401, *600423, *601604, *603345, #125853,*602843, *142640, *603044, *605740, *134830, *602779, *130660, *139191,*137035, *600761, *601340, *600823, *107740, *130160, *600877, *605110,*600945, *130080, *600957, #130050, *605580, *118444, *601124, *124020,122470, *120700, *603201, *137216, *601185, *138945, *218030, *600839,#240600, #262400, #162300, *162330, *188450, #265850, *263200, *162641,*300159, *601038, #191390, *201810, *601398, *602384, *131240, *602423,*139392, *142703, *602663, *232700, *602682, #602722, *602730, *600734,*188540, *182452, *601538, *603061, *146880, *603140, *603160, *142704,#252650, *182280, *125255, *603252, #131750, *182139, *182100, #259420,#261100, *603493, *601745, *182098, *603795, *123812, *600264, *147940,*180246, *180245, *118888, #604284, *168450, *118455, *604398, *604433,*601919, *118445, *600031, *604961, *605032, *605033, *171050, #171300,*131243, *109160, *605254, 274900, #171400, *600042, *151670, *184600,*605470, *605546, *176760, *602008, *102200, *605720, *600732, *6059012) Membrane Protein

1489 entries found, searching for “membrane protein” *130500, *605704,*305360, *153330, *173610, *109270, *170995, *170993, *104776, *602333,*309060, *605703, *120920, *605943, *602690, *159430, *600897, *133090,*601178, *602413, *602003, *604405, *605940, *603237, *109280, *600378,*602173, *107776, *602334, *602335, *125305, *601134, *309845, *605731,*154045, *603241, *603718, *600594, *603214, *185881, *603657, *600182,*603177, *605331, *601476, *605456, *601114, *605190, *600723, *603904,*136950, *300222, *602879, *185880, *605348, *300096, *602257, *177070,*310200, *603062, *603344, *600039, *602977, *300100, *128240, *600959,*600322, *227400, *186945, *600946, *602534, *602048, *182900, *601097,*600267, *602625, *136430, *602421, *601047, *107450, *143450, *603141,*184756, *164730, *159440, *154050, *600579, *312080, *604202, *603700,*600447, *256540, *604691, *158343, *600403, *602414, *137290, *176640,*176981, *600179, *600754, *604456, *604693, *605875, *604605, *188860,*300172, *602910, *604323, *219800, *601848, *603179, *600279, *602251,#222700, *603831, *605072, *605377, *601028, *604155, *108733, *104225,*601896, *601510, *173335, *107770, *601767, *600046, *603850, *600040,*603784, *603234, 188560, *605863, *121015, *605862, *605861, *186946,*604252, *603215, *142461, *604597, *603143, *605264, *603735, *176860,*605536, *176801, *180721, *603355, *104760, *131560, *310300, *602631,*304700, #309400, *603142, *143890, *605431, *600753, *115501, *176790,*600266, *601691, *168468, *601239, *602216, #104300, *605613, *601595,*605550, *125950, *605475, *602217, *602261, *603534, *602262, *604631,*190315, *601313, *604306, *104311, *604672, *605000, *602461, *605548,*602296, *604376, *121014, *121011, *600691, *604262, *139310, *304040,*605445, *179514, *179512, *151460, #160900, *120130, *128239, *601158,*601403, *176943, *601014, 300800, *300294, *601757, *185470, *273800,*605034, *602887, #185000, *604871, *603593, *603583, *605454, *104775,*605872, *141180, *602713, *603531, *139150, *601531, *601832, *605452,*134651, *604156, *120620, *605883, *604142, *166945, *605324, *600816,*604699, *300112, *605182, *600164, *182180, *605071, *300023, *605057,*308240, *300249, *176947, *176894, *605081, *605035, *602044, *182860,*107271, *305100, *153390, *113730, *602689, *180069, *603518, *300017,*191275, *177061, *601693, *601789, *604241, *600934, *138160, *604424,*603868, *600174, *600718, *600523, *604141, *601009, *605251, *600481,*600874, *155550, *605227, *601017, *162230, 601138, *604157, *601212,*600763, *604110, *604158, *601107, *601326, 600621, *600587, 601137,*600917, *600855, *605058, *194355, *605194, *603291, *102720, *136425,*170715, *603216, *605547, *135630, *602926, *600168, *605002, *602474,*600157, *603025, *603893, *231200, *120090, *601966, *131230, *604722,*604721, *604515, *246700, *602101, *605628, *303630, *605787, *602857,*602285, *605708, *602488, *605025, *603817, *300051, *603293, *176878,*603646, 605707, 185860, *112205, *300187, *602654, *120070, *603648,*604850, *602655, *602514, *300118, *182309, *179590, *602701, *600759,*204200, *604170, *175100, #103580, *147670, *306400, *143100, *182870,*257220, *180380, #116920, *301000, *193300, *157147, *131550, *139200,*139130, *190195, *605406, *155760, *155960, *605734, *155970, *605385,*111700, *155975, *150370, 605709, *151430, *605438, *151510, *116952,*157655, *158105, *605777, *176877, *153619, *120131, *185430, *109190,*120190, *109170, *605093, *605250, *153432, *107777, *186590, *160993,*605699, *605698, *605813, *605697, *605616, *605300, *162060, *605219,*163970, *135620, *165040, *605478, *604964, *103195, *604932, *604923,*605906, *605496, *605914, *166490, 138277, *604915, *114070, *605213,*605933, *180297, *101000, *191163, *191164, *605101, *603167, *600772,*603164, *600708, *604001, *191328, *313440, *602672, *604009, *604299,*192974, *604256, *603048, *600515, *604221, *602632, *604196, *601179,603290, *604661, *601023, *601110, *304800, *203200, *300212, *602933,*603352, *208900, *604418, *604838, *600551, #212140, *604837, *602049,*600552, *600553, *300213, *602574, *600583, *600932, *603452, *604775,*516020, *604617, *604464, *603498, *300145, *601523, *602694, *600632,*604762, *604492, *400015, *604504, *601717, *601728, *300242, *602426,*604194, *603821, *604730, *600695, *603823, *603869, *300241, *600707,*603822, *602370, *602202, *604193, *601181, *604089, *602507, *604195,*602306, *300284, *601805, *601895, *601275, *604660, *600752, *603820,*604192, *602207, *308230, *600894, *312600, *603199, *604029, *602500,*102680, *235200, #256300, *601633, #219700, 262890, *156225, *173470,*193400, *173910, *600354, *113705, *600065, *107741, *107400, *600024,*131195, *113811, #118220, *601638, *300011, *276903, *604144, *311770,*601758, #173900, *604592, *120120, *179605, *603130, *603372, *110750,*222900, *602509, *256100, *602469, *602281, *229300, *224100, *110900,*190180, *261600, *602997, *603616, *603189, 601791, *601567, *312700,*171060, *308700, *604027, *162643, *516000, *176261, *604028, *314850,#145980, *601383, *600930, *305900, *601253, *136350, *605537, *138140,*604033, *605070, *139250, *300500, *603967, *300041, *603866, #130600,*120150, *601050, *604942, *605204, *605248, *272750, *600163, *604235,*600682, *107266, *306900, *191092, #262500, *600106, *152790, *186720,*227650, *153700, *308380, *$$03390, *605646, *164920, *604478, #252650,*173850, *173350, *602505, *246530, *194380, *602575, *603030, #209920,*212138, #214100, *605767, *600582, *189980, #176200, *604653, *604678,*256550, *300037, *253700, #253300, #226700, *604766, #244400, *190000,*188040, *604824, *214500, #237500, *232300, *605014, *604477, *190930,*605124, *604475, *604594, #227810, *306700, #301050, *600135, *600143,*605145, #2699$$0, *300104, *277900, *300135, *300231, *192500, *182138,*191190, *176805, *600185, *186591, *604889, *603051, *165360, *147545,*601040, #156575, *107269, *603009, *602934, *123825, *60$$081, *602924,*163890, *600381, *602909, *150330, *109690, *1$$3900, *603434, *603491,*110700, *602581, *125647, #154700, *114760, *141900, *603690, *120220,*601199, #145500, *601309, *602382, *120325, *600877, *604205, *604090,601497, *602377, *605464, *138720, *603728, *120950, *604026, *600580,*601610, *137167, *603960, *603931, *601880, *603126, *138190, *130130,*601997, *601975, *600395, *516040, *600418, *600650, *605245, *605172,*600509, *16476$$, *310400, *600308, *605109, *600544, *600359, *600103,*6052$$7, *312610, *176100, *308100, *158070, *605123, *173325,#312$$50, *600839, *158120, #604369, *604465, *173510, #161200, *151525,*605369, *604237, *516050, #600886, *604517, *165180, *605381, *605399,*307800, *604365, *155740, *147795, 601709, *604673, *147730, *602122,*147557, *193245, *600978, *604990, *603261, *603274, *601007, *131100,*602941, *107941, *146710, *276901, *131244, *602872, *603411, *186357,*176290, *601066, *185050, *232200, *143030, *601843, #236700, *604122,*142800, *134638, *604985, *182380, *603930, *142410, *137060, *604586,*601193, *120650, *252500, *253800, *120930, *604858, *605874, 601274,*602158, *605873, *193210, *203100, *601295, *604095, #201710, *126150,*108740, #205400, *601373, *300167, *109545, *602894, *603361, #300257,*266200, *603401, *131390, *180470, *605908, *604798, #221770, *223360,*180901, *605641, *605745, *604018, *300200, *604603, *230800, *602676,#604004, *605692, *602640, *601599, *134637, *245900, *118425, 601614,*605725, *120110, *300189, *300035, *603102, *250800, *602282, *602458,*123610, *603754, *300278, *601463, *300224, *601581, *182160, *601653,*139191, *601733, *600748, *142460, *601194, *152390, *153620, *601615,*601814, *601617, *601613, *300191, #308300, *600798, 601858, *601872,*601597, #601588, *600821, *147840, *152427, *138850, *600823, *601492,*300256, *600840, *300267, *601411, *139080, *139090, 600851, *300334,*179080, *602095, *601284, *601282, #177200, *601681, *601252, *176000,*602184, *602188, #266510, #154020, *186711, *257200, *601711, *600667,*602241, *186745, *255125, *300126, *600644, *123890, #255120, #175200,*600004, *302060, *123580, *186760, *122561, *602316, *600017, *120940,140300, *151690, *120700, *602354, *600019, *600857, *182175, *600536,*158380, *600516, *120290, *600493, *182310, #252010, *182530, *186830,*601839, *142790, *159465, *118990, *250790, *248600, #248250, *186845,*601153, *142600, *116930, *114860, *171834, #303600, *186880, *600444,*142871, *601852, *602602, *602607, *114207, *186910, #232220, 600880,*134635, *112203, #112100, *111680, *231680, *311030, *111250, *111200,*134390, #226670, #145600, *226200, *602714, *171760, *133550, *602727,*161555, *602744, *602746, #131705, *602835, *600423, *176267, *602859,#600918, 277175, *602874, *601020, *109770, *600170, *217070, *173515,*602893, *147280, *154360, *171050, *108780, *176257, *600979, *600377,*108360, *204500, *170260, *146880, *154582, *601011, *600997, *602992,*201475, *603005, *190198, *147360, #270400, *600238, #164970, *306250,#126600, *193065, #181350, *106180, *602136, *600937, *603086, *603087,*307030, *182099, *103320, *601683, #192430, *103180, *102681, *192321,*600244, *191740, *191315, *603152, *102642, *191305, #266140, *100500,*600867, *604585, *604404, *604345, *603201, *605430, *603207, *603208,*605433, *604101, *603969, *605896, *604616, *605851, *605768, *604576,*605754, *605730, *605477, *603263, *605538, *603283, *604402, *605453,*605427, *603302, *605458, 603313, *604415, *603345, *605541, *603353,*605295, *603879, *605268, *605266, *605246, *603377, *603380, *605181,*604203, *603425, *603867, *605106, *605017, *603842, *604936, *603510,*604857, *605932, *605816, *603765, *603551, *605357, *605237, *604204,*603594, *605110, *604190, *603861, *604962, *603639, *603644, *605007,*605349, *604943, *604918, *604907, *603667, *603681, *605396, *605561,*603712, *603713, *605688, *605942, *604878, *604843, *604659, *604671,*603798, *604682, *604056, *604705, *603749, 602586, *603647, *602515,#602475, *603717, *602359, *602372, *602380, *602518, *603652, *602573,*603626, 602587, *603598, *602871, *603613, *603750, *603875, *602608,*602666, *602345, *602935, *603564, *603548, *603927, 601876, *602343,*603943, *603787, *601730, *601611, *602679, *603788, *602243, 603790,*601535, *603796, *601488, *601485, *602314, *601478, *604047, *604048,*602297, *604057, *602715, *602192, *601459, *601416, *603833, *602190,*604102, *602106, *604111, *602724, *603499, *602736, *601123, *601002,*600923, *601987, *604149, *601929, *600910, *600900, *600864, *604165,*600782, *602836, *600769, *600742, *602783, *601905, *600535, *604198,*601901, *600534, *602876, *603356, *600530, *604216, *604217, *602890,*602905, *600465, *600464, *600446, *602891, *603366, *601894, *604272,*603926, *603312, *600368, *602914, *600327, *603151, *603202, 602911,*602974, *603006, *601883, *603008, *600074, *603007, *603046, #603903,*604433, *600016, *603925, *516005, *516004, *516003, *601756, *604487,*516001, *313475, *313470, #307810, *604527, *604528, *601745, *604551,*604555, *603243, *603242, *603061, *603063, *603217, *300335, *300283,*300281, *604600, *300197, *603097, *603220, *601625, *604623, *603118,*601590, *604646, *300008, *601568, *300007, *275630, *601533, #275200,*270200, #261550, *604031, *604683, #254800, *251100, #242300, *604058,*604720, *240500, *233690, #232240, #226730, *223100, *222100, #220100,*216950, *604832, 212750, 212067, *604066, *193067, 601315, *193001,*604862, *604870, *191306, *600385, *604879, *191191, *601296, *604914,*190181, *604119, #188550, *604925, *188410, #601287, *604939, *188380,*604126, *604945, *604148, *188060, *604982, *186854, *604988, *186360,*186355, *185250, *600916, *605008, *605009, 185020, *600734, *605024,*182331, *605032, *605033, *182305, *180903, #179800, *179610, *605060,*179410, *178990, *176802, *605080, *176266, *176263, *176260, *600732,*173490, *604199, *173445, *173391, 172290, *605147, *605149, *171890,*600528, *171833, *605185, #170500, *605193, #168000, *605196, *167055,*605205, *605208, 166900, *605216, *162651, *162010, *600504, #161400,*604253, #160800, *159460, *154540, *605254, *605261, *153634, *600429,*153337, *600424, *605292, #604286, #152700, 152423, *152310, *151625,*600153, *604313, *151523, *150325, *150320, *150292, *603150, *150290,*150210, *605410, *605415, *605416, *605417, *605421, *603149, *604349,*147940, *600282, *147880, *146928, *146661, *600150, *146630, *142622,*600018, *605461, *138981, *138590, *600023, *138330, *605495, *138297,*605512, *138230, #136900, #301310, *516006, *605545, *605546, *136131,*134660, *134350, *516002, *605589, *131235, #130050, *605625, *126455,*126064, #125310, *605670, *604534, *125240, *123836, *123830, *123620,*605702, #122200, *120980, *120360, *118510, *114835, *605710, *605716,*605722, *114217, *604561, *113810, *111740, #110800, *605748, *605752,*604564, *110600, *603160, *109610, *605784, #107480, *107273, *603192,*300169, *106195, *105210, *104615, *104614, *104210, *103850, 103581,*605876, *605877, *605879, *103220, *605887, *300150, *102910, *102670,*102576, *605916, *604629, *102575, *102573, *300132, *101800, *6059473) Channel (Member of Membrane Protein)

361 entries found, searching for “channel” *176266, *600724, *182390,*123825, *114208, *114206, *176267, *114205, *601784, *600937, *114204,*603415, *600053, *114207, *114209, *605427, *604527, *604528, *600760,*601011, *192500, *118425, *600228, *176261, *602235, *600761, *600359,*300008, *182389, *600877, *602232, *176263, *182391, *601328, *600054,*603939, *602208, *601534, *600504, *602323, *603208, *601958, *603537,*601012, *601327, *600734, *602780, *602781, *604433, *603220, *182392,*605874, *605873, *601745, *603888, *603219, *602604, *603796, *302910,*602866, *601013, *602905, *602906, *603967, *600163, #170500, *152427,*180901, *176260, #601462, *603951, *601141, *604492, *600702, *602023,*600308, *602754, *107776, *176257, *602024, *601949, *605222, *601142,*602983, *193245, *600681, *176265, *600235, *176262, *176258, *605206,*604427, *605411, *603305, *601219, *600150, *604065, *602343, *605223,*605720, *603906, *138249, *138253, *600843, *604385, *600003, *600935,*603940, *602727, *602158, 602911, *600397, *602726, *600845, *605080,*600580, *602872, *602106, *176264, *603953, *605722, *300110, *138252,*604111, *602717, *602420, *600570, 600844, *603493, *600932, *605716,*138254, *603652, *300138, *605410, *176268, *605214, *605696, *300334,*604660, *176256, *605879, *603749, *603583, *602345, *604661, *603787,603313, *602982, *604337, *600846, *604662, *300328, *300281, *602566,*602836, *604003, *603788, *603651, *602421, *107777, #177200, *100725,#219700, *100690, *100710, #160800, #603830, #183086, *600509, #220400,#601144, *173910, *180902, *605692, #264350, #160900, #145600, #255700,*602076, *603061, *601313, *154275, #604233, *604532, #108500, #121201,#170400, *300225, *121014, *139311, #125800, #160120, *118503, 601439,#141500, #168300, *304040, #601887, #256450, *186945, *154276, #300009,#216900, *600040, *601014, *601042, *602512, *601383, *605445, *602368,*603831, #117000, *601218, *108745, *605248, #177735, #173900, *601212,*182139, *601059, *600039, *601485, *180903, *186360, *603319, #600101,*118509, *600109, #121200, *600170, *604187, *176975, *137163, #310468,#263800, #262300, *603750, *600229, *124030, *602251, #603829, *137143,#145500, *600669, *147450, *154050, *603353, *600516, *601157, *600855,*601154, *602522, *249210, *600968, #252650, *171060, *600919, *156490,#259700, #601678, *601764, #310500, *131244, *300041, *121011, *125950,*114180, *602974, *600637, *113730, *118504, *605145, *604669, *118800,*121013, *121015, *138491, *600421, *104610, *604045, *604594, *131230,*605487, *138247, *600467, #602485, *602481, *138251, *137192, *602403,600851, *277900, *603785, *603152, *603199, *603475, #168600, #272120,*170280, *603852, #241200, *603053, *600465, #603034, *142461, *164920,*137164, *600884, *600442, *123885, *604001, *600232, *232200, *171050,*602103, *602014, *300211, *600983, *602887, *604415, *604418, *300242,#300071, *604471, *600837, 168350, *118511, 193007, *600300, *604654,#601820, *180297, *600046, *603853, *604678, *604693, #604772, *118508,*603855, *605204, #254210, *182099, *182307, #130600, *601109, *114080,*300103, *182860, *605438, *601129, *603964, *600019, *516060, #185000,*138079, *104210, *605818, *603418, *305990, *3054504) Extracellular Matrix

218 entries found, searching for “extracellular matrix” *605912,*603479, *602201, *604633, *601418, *601548, *115437, *154870, *600754,*602261, *602285, *602262, *134797, *120361, *604629, *604871, *603321,*603320, *601807, #154700, *116935, *185261, *120360, *185250, *605470,*603767, *253700, *190180, *128239, *308700, *276901, *193300, *120324,*188826, *602109, *155760, *600514, *600261, #177170, *600536, *147557,#116920, *150240, *601313, *120140, 601614, *605158, *120150, *120180,#200610, *605127, *193400, *192240, #173900, *152200, #136900, *135821,#130070, *120320, *120220, *112260, *310200, *600900, *600262, *605670,*600985, *179590, #245150, *602574, *601463, 183850, *601211, *604241,*600758, *186745, *604710, *602369, *602090, *190182, *192975, *602178,*230740, *600065, *601652, *158106, *190181, *156790, #158810, *193210,*155120, *192977, *193065, #226700, *187380, *231050, *182120, *188060,*186355, 163200, *164010, #156550, *151510, *150370, *253800, *156225,*150325, #194050, *150290, *216550, *147620, *600215, *222600, *147559,*165380, *182888, *600491, *146650, *146640, *600564, *600596, *600616,*600700, *600742, *138297, *182889, *154705, *600930, *301870, *153619,*601050, *601090, *601105, *165070, *305370, *135820, *130660, *310300,*601492, *128240, *601587, #126600, *601636, *600119, *601692, *601728,*125485, 601858, *601915, *602048, *175100, *602108, *121010, *600245,*120470, *120328, *120325, *602264, *120280, *602366, *600309, *602402,*602415, *602428, *602453, *602505, #166210, *602600, *602941, *603005,*603196, 603209, *603221, *603234, *603319, *120250, *120210, *120120,*603489, *603551, *118938, *603799, *603842, *603924, *603963, *604042,*604063, *604149, *604160, *601028, *604467, *604510, *604592, *116930,*116806, *601284, *604724, *604806, *604807, *604808, *107269, *605007,*605008, *605009, *600214, *600076, *605174, *605175, *605292, *605343,*605351, #600204, *605497, *605546, *605587, *605623, *600211, *605702,*103320

In addition to these, the various keywords shown in the above-mentionedcategorization or others can be used for the OMIM search and the resultmay suggest the involvement thereof in diseases.

Further, the use of nucleotide sequences of cDNAs of the presentinvention enables analyzing the expression frequency of genescorresponding to the cDNAs. In addition, functions of the genes can bepredicted based on the information obtained by the expression frequencyanalysis.

There are several methods for analyzing the expression levels of genesinvolved in diseases. Differences in gene expression levels betweendiseased and normal tissues are studied by the analytical methods using,for example, Northern hybridization, RT-PCR, DNA microarray, etc.(Experimental Medicine, Vol. 17, No. 8, 980-1056 (1999); CellEngineering (additional volume) DNA Microarray and Advanced PCR Methods,Muramatsu & Nawa (eds.), Shujunsya (2000)). By computer analysis, inaddition to these analysis methods, the nucleotide sequences ofexpressed genes can be compared to analyze the expression frequency. Forexample, there is a database called “BODYMAP”; gene clones are extractedat random from cDNA libraries of various tissues and/or cells, and theclones homologous to one another are assigned to a single cluster basedon the information of nucleotide sequence homology at the 3′-end; genesare classified into any clusters, and the numbers of clones in therespective clusters are compared to gain the information on expressionfrequency (http://bodymap.ims.u-tokyo.ac.jp/).

When explicit difference in the expression levels between diseasedtissues and normal tissues is observed for a gene by these analyticalmethods, it can be conclude that the gene is closely involved in adisease or disorder. Instead of diseased tissues, when gene expressionis explicitly different between normal cells and cells reproducingdisease-associated specific features, it can be concluded that the geneis closely involved in a disease or disorder.

From the 1970 clones whose full-length nucleotide sequences had beenrevealed, genes involved in particular pathology or functions wereselected by the use of databases shown below (see Example 7; “Expressionfrequency analysis in silico”). The database used in the analyses of thepresent invention contains nucleotide sequences of 770,546 clones, andthe population of the database is large enough for the analysis. Thesequence information in the database was obtained by selecting cDNAclones at random from cDNA libraries derived from the various tissuesand cells shown in Example 1 and determining the 5′-end sequencesthereof.

Then, the nucleotide sequences of respective clones in this databasewere categorized (clustered) based on the nucleotide sequence homologydetermined with a search program; the number of clones belonging toevery cluster of each library was determined and normalized; thus, theratio of a certain gene in a cDNA library was determined. This analysisprovided the information of the expression frequency of a gene in atissue or cell that is the source of the cDNA library.

Then, in order to analyze the expression of genes corresponding to thenucleotide sequences of cDNAs of the present invention in tissues andcells, the libraries from the tissues or cells, which had been used inthe large-scale cDNA analyses, were taken as subjects to compare theexpression levels between different tissues or cells. Namely, theexpression frequency was analyzed by comparing the previously normalizedvalues between tissues or cells from which 600 or more cDNA clones whosenucleotide sequences had been analyzed were derived. The result of thisanalysis showed that the cDNA clones corresponded to the genes involvedin the pathology and functions, which are indicated below. Each value inTables 3 to 39 indicated below represents a relative expressionfrequency; the higher the value, the higher the expression level.

Osteoporosis-Related Genes

Osteoporosis is a pathology in which bones are easily broken owing tooverall decrease in components of bone. The onset correlates to thebalance between the functions of osteoblast producing bone andosteoclast absorbing bone, namely bone metabolism. Thus, the genesinvolved in the increase of osteoclasts differentiating from precursorcells of monocyte/macrophage line (Molecular Medicine 38. 642-648.(2001)) are genes involved in osteoporosis relevant to bone metabolism.

A nucleotide sequence information-based analysis was carried out toidentify the genes whose expression frequencies are higher or lower inCD34+ cell (cell expressing a glycoprotein CD34) treated with theosteoclast differentiation factor (Molecular Medicine 38. 642-648.(2001)) than in the untreated CD34+ cell, which is the precursor cell ofmonocyte/macrophage line. The result of comparative analysis for thefrequency between the cDNA libraries prepared from the RNA of CD34+cells (CD34C) and from the RNA of CD34+ cells treated with theosteoclast differentiation factor (D30ST, D60ST or D90ST) showed thatthe genes whose expression levels were different between the two were 26clones indicated in Table 3. These clones are involved in osteoporosis.

Genes Involved in Neural Cell Differentiation

Genes involved in neural cell differentiation are useful for treatingneurological diseases. Genes with varying expression levels in responseto induction of cellular differentiation in neural cells are thought tobe involved in neurological diseases.

A survey was performed for genes whose expression levels are varied inresponse to induction of differentiation (stimulation by retinoic acid(RA) or growth inhibitor treatment after RA stimulation) in culturedcells of a neural strain, NT2. The result of comparative analysis ofcDNA libraries derived from undifferentiated NT2 cells (NT2RM) and thecells subjected to the differentiation treatment (NT2RP, NT2RI or NT2NE)showed that the genes whose expression levels were different between thetwo were 193 clones indicated in Table 4. These genes are neurologicaldisease-related genes.

Cancer-Related Genes

It has been assumed that, distinct from normal tissues, cancer tissuesexpress a distinct set of genes, and thus the expression thereof cancontribute to the carcinogenesis in tissues and cells. Thus, genes whoseexpression patterns in cancer tissues are different from those in normaltissues are cancer-related genes. Search was carried out for the geneswhose expression levels in cancer tissues were different from those innormal tissues.

The result of comparative analysis of cDNA libraries derived from breasttumor (TBAES) and normal breast (BEAST) showed that the genes whoseexpression levels were different between the two were 4 clones indicatedin Table 5.

The result of comparative analysis of cDNA libraries derived cervicaltumor (TCERX) and normal cervical duct (CERVX) showed that the geneswhose expression levels were different between the two was one cloneindicated in Table 6.

The result of comparative analysis of cDNA libraries derived from colontumor (TCOLN) and normal colon (COLON) showed that the genes whoseexpression levels were different between the two was one clone indicatedin Table 7.

The result of comparative analysis of cDNA libraries derived fromesophageal tumor (TESOP) and normal esophagus (NESOP) showed that thegenes whose expression levels were different between the two were 6clones indicated in Table 8.

The result of comparative analysis of cDNA libraries derived from kidneytumor (TKIDN) and normal kidney (KIDNE) showed that the genes whoseexpression levels were different between the two were 132 clonesindicated in Table 9.

The result of comparative analysis of cDNA libraries derived from livertumor (TLIVE) and normal liver (LIVER) showed that the genes whoseexpression levels were different between the two were 25 clonesindicated in Table 10.

The result of comparative analysis of cDNA libraries derived from lungtumor (TLUNG) and normal lung (HLUNG) showed that the genes whoseexpression levels were different between the two were 99 clonesindicated in Table 11.

The result of comparative analysis of cDNA libraries derived from ovarytumor (TOVER) and normal ovary (NOVER) showed the genes whose expressionlevels were different between the two were 3 clones indicated in Table12.

The result of comparative analysis of cDNA libraries derived fromstomach tumor (TSTOM) and normal stomach (STOMA) showed that the geneswhose expression levels were different between the two were 15 clonesindicated in Table 13.

The result of comparative analysis of cDNA libraries derived fromuterine tumor (TUTER) and normal uterus (UTERU) showed that the geneswhose expression levels were different between the two were 97 clonesindicated in Table 14.

The result of comparative analysis of cDNA libraries derived from tonguecancer (CTONG) and normal tongue (NTONG) showed that the genes whoseexpression levels were different between the two were 203 clonesindicated in Table 15.

These genes are involved in cancers.

Further, there is a method to search for genes involved in developmentand differentiation, which is the expression frequency analysis in whichthe expression levels of genes are compared between developing and/ordifferentiating tissues and/or cells and adult tissues and/or cells. Thegenes involved in tissue development and/or differentiation are genesparticipating in tissue construction and expression of function, andthus are useful genes, which are available for regenerative medicineaiming at convenient regeneration of injured tissues.

By using the information of gene expression frequency gained from thedatabase of 5′-end nucleotide sequences described above, genes involvedin development or differentiation of particular tissues were selectedfrom the 1970 clones whose full-length nucleotide sequence had beenrevealed (see Example 7).

The result of comparative analysis of cDNA libraries derived from fetalbrain (FCBBF, FEBRA or OCBBF) and adult brain (BRACE, BRALZ, BRAMY,BRAWH, BRCAN, BRCOC, BRHIP, BRSSN, BRSTN or BRTHA) showed that the geneswhose expression levels were different between the two were 775 clonesindicated in Tables 16 to 36.

The result of comparative analysis of cDNA libraries derived from fetalheart (FEHRT) and adult heart (HEART) showed that the genes whoseexpression levels were different between the two were 28 clonesindicated in Table 37.

The result of comparative analysis of cDNA libraries derived from fetalkidney (FEKID) and adult kidney (KIDNE) showed that the genes whoseexpression levels were different between the two were 95 clonesindicated in Table 38.

The result of comparative analysis of cDNA libraries derived from fetallung (FELNG) and adult lung (HLUNG) showed that the genes whoseexpression levels were different between the two were 99 clonesindicated in Table 39. These genes are involved in regeneration oftissues and/or cells.

The expression frequency or the like can be analyzed by PCR based on thenucleotide sequences of cDNAs of the present invention. There are someknown methods for comparing the quantities of amplification productsobtained by PCR. For example, the band intensities can be determined byethidium bromide staining. With R1-labeled or fluorescently labeledprimers, the R1 signal or fluorescence intensity can be assayed for thequantity of labeled amplification products. Alternatively, the quantityof amplification products can also be determined by measuring the RIsignal or the fluorescence intensity from the RI-labeled orfluorescently labeled probe hybridizing to the products. The assayresults thus obtained are compared and then the clones exhibitingdifferences in the expression levels can be selected.

There are some quantitative PCR methods: a PCR method using internalstandards; a competitive PCR, in which the quantification is achieved byadding, to a sample, a dilution series of a known quantity of a templateRNA and by comparing the quantity of an amplification product derivedfrom the RNA of interest with the quantity of an amplification productderived from the template RNA. These methods overcome the problems oferrors in the amount of amplification products among tubes and of theplateau effect. ATAC-PCR (Adaptor-tagged competitive PCR) is a method ofcompetitive PCR which is practiced by using multiple adapters ofdifferent sizes attached to a gene whose 3′-end nucleotide sequence haspreviously been determined. The ratio of expression frequency of asingle mRNA species from a number of tissues (cells) can be assayed in asingle step (Nucleic Acids Research 1997, 25 (22): 4694-4696; “DNAMicro-array and Advanced PCR Techniques”, Cell Technology, supplement,Eds., Muramatsu and Nawa (Shujunsha, 2000): 104-112).

If it is observed, by using these analytical methods, that theexpression levels of genes are evidently varied during major cellularevents (such as differentiation and apoptosis), the genes are involvedin the cellular events and accordingly are candidates for disease-and/or disorder-related genes. Further, genes exhibiting tissue-specificexpression are genes playing important parts in the tissue functionsand, therefore, can be candidates for genes involved in diseases and/ordisorders affecting the tissues.

For example, inflammation is an important biological response that isknown to be involved in various diseases. The representativeinflammation-inducing factors include TNF-α (Tumor NecrosisFactor-alpha). There exists a signaling cascade activated by TNF-αstimulations, wherein NF-κB is a transducing molecule (Cell 1995,80:529-532). It has also been revealed that many inflammation-relatedgenes, including IL-2, IL-6 and G-CSF, are varied in the expressionlevels thereof in response to the signal through the pathway (TrendsGenet. 1999, 15 (6): 229-235). It is assumed that genes whose expressionlevels are varied in response to the stimulation of TNF-α alsoparticipate in inflammation.

Further, the infection of Helicobacter pylori to the gastric epitheliais known to cause gastritis and gastroduodenal ulcer (Mebio 2000, July,17 (7): 16-33). Thus, the genes whose expression levels are altereddepending on co-culturing cells with Helicobacter pylori may be involvedin gastritis and gastroduodenal ulcer. A recent study has suggested thatHelicobacter pylori strongly activates the NF-κB pathway(Gastroenterology 2000, 119: 97-108).

THP-1 cell, which is a human monocyte cell line, was cultured in thepresence of TNF-α (Tumor Necrosis Factor-alpha). The genes whoseexpression levels were altered owing to the presence of TNF-α weresearched for, and the result showed that the clones whose expressionlevels were increased owing to the presence of TNF-α were ASTRO20055530,ASTRO20055930, ASTRO20088950, BRAMY20027390, BRAMY20076130,BRAMY20118410, BRAMY20125360, BRAMY20237190, BRCAN20001480,BRHIP10000720, CD34C20001750, CTONG20078340, CTONG20085210,DFNES20063460, FCBBF20029280, FCBBF20033360, FCBBF30078600,FEBRA20007820, FEBRA20031280, FEBRA20031810, FEBRA20040290,HLUNG20041540, HLUNG20092530, MESAN20021860, MESAN20067430,MESAN20084150, NT2NE20092950, NT2RP70031070, OCBBF20012520,OCBBF20142290, OCBBF20165900, OCBBF20170350, OCBBF20176650,PLACE60006300, PROST20011160, PROST20106060, SPLEN20040780,SPLEN20110860, SPLEN20177400, TESTI20030610, TESTI20043130,TESTI20059370, TESTI20254480, THYMU10004280, THYMU20030460,THYMU20062520, THYMU20078240, THYMU20150190, TRACH20090060,TRACH20125620, UTERU20026620, UTERU20045200, UTERU20064120,UTERU20103200.

On the other hand, the clones whose expression levels were decreasedowing to the presence of TNF-α were BNGH420052350, BRACE20052530,BRAMY20003880, CTONG20170940, FCBBF30022680, FCBBF30225930,FCBBF30257370, FEBRA20046280, KIDNE20084030, KIDNE20188630,NT2NE20082130, OCBBF20110210, PLACE60061370, PROST20041460,PROST20075280, PROST20110120, SMINT20006020, TESTI20046540,TESTI20057200, TESTI20113940, TESTI20257910, TESTI20262940,TRACH20149740.

These clones are inflammation-related genes.

MKN45, which is a gastric cancer cell line, was co-cultured withHelicobacter pylori. The genes whose expression levels were alteredowing to the presence of Helicobacter pylori were searched for, and theresult showed that the clones whose expression levels were increasedowing to the presence of Helicobacter pylori were BRAMY20028530,BRAMY20035380, OCBBF20170350, PROST20011160, SKMUS20091900,SPLEN20040780, THYMU20078240, TRACH20190460, UTERU20045200,UTERU20064120, ASTRO20055530, CTONG20170940, FEBRA20040290,MESAN20067430, PROST20016760, THYMU10004280, TRACH20090060,UTERU20041970, OCBBF20142290, TESTI20030610.

On the other hand, the clones whose expression levels were decreasedowing to the presence of Helicobacter pylori were ASTRO20088950,BRACE20052530, BRAMY20003880, BRAMY20027390, BRAMY20036530,BRAMY20118410, BRHIP20000210, FCBBF20032930, FCBBF30022680,FCBBF30169870, FEBRA20182030, KIDNE20182540, LIVER20007750,MESAN20021220, NT2NE20059210, NT2NE20082130, OCBBF20155030,PROST20065100, PROST20075280, SPLEN20110860, TESTI20057200,TESTI20113940, TESTI20149880, TESTI20151800, TESTI20198600,TESTI20257910, THYMU20046770, THYMU20058550, THYMU20150190,FCBBF20033360, FCBBF30257370, FEBRA20098040, SMINT20006020.

These clones are involved in gastritis or gastroduodenal ulcer.

For example, if the polypeptide encoded by the cDNA of the presentinvention is a regulatory factor of cellular conditions such as growthand differentiation, it can be used for developing medicines as follows.The polypeptide or antibody provided by the invention is injected into acertain kind of cells by microinjection. Then, using the cells, it ispossible to screen low molecular weight compounds, etc. by measuring thechange in the cellular conditions, or the activation or inhibition of aparticular gene. The screening can be performed as follows.

First, the polypeptide is expressed and purified as recombinant. Thepurified polypeptide is microinjected into cells such as various celllines, or primary culture cells, and the cellular change such as growthand differentiation can be examined. Alternatively, the induction ofgenes whose expression is known to be involved in a particular change ofcellular conditions may be detected by the amount of mRNA orpolypeptide. Alternatively, the amount of intracellular molecules (lowmolecular weight compounds, etc.) that is changed by the function of thegene product (polypeptide) which is known to be involved in a particularchange of cellular conditions may be detected.

The compounds to be screened (both low and high molecular compounds areacceptable) can be added to the culture media and assessed for theiractivity by measuring the change of the cellular conditions.

Instead of microinjection, cell lines introduced with the gene obtainedin the invention can be used for the screening. If the gene product isturn out to be involved in a particular change in the cellularconditions, the change of the product can be used as a measurement forscreening. Once a compound is screened out which can activate or inhibitthe function of the polypeptide of the invention, it can be applied fordeveloping medicines.

If the polypeptide encoded by the cDNA of the present invention is asecretory protein, membrane protein, or protein involved in signaltransduction, glycoprotein, transcription, or diseases, it can be usedin functional assays for developing medicines.

In case of a membrane protein, it is most likely to be a polypeptidethat functions as a receptor or ligand on the cell surface. Therefore,it is possible to reveal a new relationship between a ligand andreceptor by screening the membrane protein of the invention based on thebinding activity with the known ligand or receptor. Screening can beperformed according to the known methods.

For example, a ligand against the polypeptide of the invention can bescreened in the following manner. Namely, a ligand that binds to aspecific polypeptide can be screened by a method comprising the stepsof: (a) contacting a test sample with the polypeptide of the inventionor a partial peptide thereof, or cells expressing these, and (b)selecting a test sample that binds to said polypeptide, said partialpeptide, or said cells.

On the other hand, for example, screening using cells expressing thepolypeptide of the present invention that is a receptor protein can alsobe performed as follows. It is possible to screen receptors that iscapable of binding to a specific polypeptide by using procedures (a)attaching the sample cells to the polypeptide of the invention or itspartial peptide, and (b) selecting cells that can bind to the saidpolypeptide or its partial peptide.

In a following screening as an example, first the polypeptide of theinvention is expressed, and the recombinant polypeptide is purified.Next, the purified polypeptide is labeled, binding assay is performedusing a various cell lines or primary cultured cells, and cells that areexpressing a receptor are selected (Growth and differentiation factorsand their receptors, Shin-Seikagaku Jikken Kouza Vol. 7 (1991) Honjyo,Arai, Taniguchi, and Muramatsu edit, p203-236, Tokyo-Kagaku-Doujin). Apolypeptide of the invention can be labeled with RI such as ¹²⁵I, andenzyme (alkaline phosphatase etc.).

Alternatively, a polypeptide of the invention may be used withoutlabeling and then detected by using a labeled antibody against thepolypeptide. The cells that are selected by the above screening methods,which express a receptor of the polypeptide of the invention, can beused for the further screening of an agonists or antagonists of the saidreceptor.

Once the ligand binding to the polypeptide of the invention, thereceptor of the polypeptide of the invention or the cells expressing thereceptor are obtained by screening, it is possible to screen a compoundthat binds to the ligand and receptor. Also it is possible to screen acompound that can inhibit both bindings (agonists or antagonists of thereceptor, for example) by utilizing the binding activities.

When the polypeptide of the invention is a receptor, the screeningmethod comprises the steps of (a) contacting the polypeptide of theinvention or cells expressing the polypeptide of the invention with theligand, in the presence of a test sample, (b) detecting the bindingactivity between said polypeptide or cells expressing said polypeptideand the ligand, and (c) selecting a compound that reduces said bindingactivity when compared to the activity in the absence of the testsample. Furthermore, when the polypeptide of the invention is a ligand,the screening method comprises the steps of (a) contacting thepolypeptide of the invention with its receptor or cells expressing thereceptor in the presence of samples, (b) detecting the binding activitybetween the polypeptide and its receptor or the cells expressing thereceptor, and (c) selecting a compound that can potentially reduce thebinding activity compared to the activity in the absence of the sample.

Samples to screen include cell extracts, expressed products from a genelibrary, synthesized low molecular compound, synthesized peptide, andnatural compounds, for example, but are not construed to be listed here.A compound that is isolated by the above screening using a bindingactivity of the polypeptide of the invention can also be used as asample.

A compound isolated by the screening may be a candidate to be an agonistor an antagonist of the receptor of the polypeptide. By utilizing anassay that monitors a change in the intracellular signaling such asphosphorylation which results from reduction of the binding between thepolypeptide and its receptor, it is possible to identify whether theobtained compound is an agonist or antagonist of the receptor. Also, thecompound may be a candidate of a molecule that can inhibit theinteraction between the polypeptide and its associated proteins(including a receptor) in vivo. Such compounds can be used fordeveloping drugs for precaution or cures of a disease in which thepolypeptide is involved.

Secretory proteins may regulate cellular conditions such as growth anddifferentiation. It is possible to find out a novel factor thatregulates cellular conditions by adding the secretory protein of theinvention to a certain kind of cell, and performing a screening byutilizing the cellular changes in growth or differentiation, oractivation of a particular gene.

The screening can be performed, for example, as follows. First, thepolypeptide of the invention is expressed and purified in a recombinantform. Then, the purified polypeptide is added to a various kind of celllines or primary cultured cells, and the change in the cell growth anddifferentiation is monitored. The induction of a particular gene that isknown to be involved in a certain cellular change is detected by theamounts of mRNA and polypeptide. Alternatively, the amount of anintracellular molecule (low-molecular-weight compounds, etc.) that ischanged by the function of a gene product (polypeptide) that is known tofunction in a certain cellular change is used for the detection.

Once the screening reveals that the polypeptide of the invention canregulate cellular conditions or the functions, it is possible to applythe polypeptide as a pharmaceutical and diagnostic medicine for relateddiseases by itself or by altering a part of it into an appropriatecomposition.

As is above described for membrane proteins, the secretory proteinprovided by the invention may be used to explore a novel ligand-receptorinteraction using a screening based on the binding activity to a knownligand or receptor. A similar method can be used to identify an agonistor antagonist. The resulting compounds obtained by the methods can be acandidate of a compound that can inhibit the interaction between thepolypeptide of the invention and an interacting molecule (including areceptor). The compounds may be able to use as a preventive,therapeutic, and diagnostic medicine for the diseases, in which thepolypeptide may play a certain role.

Proteins involved in signal transduction or transcription may be afactor that affects a certain polypeptide or gene in response tointracellular/extracellular stimuli. It is possible to find out a novelfactor that can affect a polypeptide or gene by expressing thepolypeptide provided by the invention in a certain types of cells, andperforming a screening utilizing the activation of a certainintracellular polypeptide or gene.

The screening may be performed as follows. First, a transformed cellline expressing the polypeptide is obtained. Then, the transformed cellline and the untransformed original cell line are compared for thechanges in the expression of a certain gene by detecting the amount ofits mRNA or polypeptide. Alternatively, the amount of an intracellularmolecule (low molecular weight compounds, etc.) that is changed by thefunction of a certain gene product (polypeptide) may be used for thedetection. Furthermore, the change of the expression of a certain genecan be detected by introducing a fusion gene that comprises a regulatoryregion of the gene and a marker gene (luciferase, β-galactosidase, etc.)into a cell, expressing the polypeptide provided by the invention intothe cell, and estimating the activity of a marker gene product(polypeptide).

If the polypeptide or gene of the invention is involved in diseases, itis possible to screen a gene or compound that can regulate itsexpression and/or activity either directly or indirectly by utilizingthe polypeptide of the present invention.

For example, the polypeptide of the invention is expressed and purifiedas a recombinant polypeptide. Then, the polypeptide or gene thatinteracts with the polypeptide of the invention is purified, andscreened based on the binding. Alternatively, the screening can beperformed by adding with a compound of a candidate of the inhibitoradded in advance and monitoring the change of binding activity. Inanother method, a transcription regulatory region locating in the5′-upstream of the gene encoding the polypeptide of the invention thatis capable of regulating the expression of other genes is obtained, andfused with a marker gene. The fusion is introduced into a cell, and thecell is added with compounds to explore a regulatory factor of theexpression of the said gene.

The compound obtained by the screening can be used for developingpharmaceutical and diagnostic medicines for the diseases in which thepolypeptide of the present invention is involved. Similarly, if theregulatory factor obtained in the screening is turn out to be apolypeptide, compounds that can newly affect the expression or activityof the polypeptide may be used as a medicine for the diseases in whichthe polypeptide of the invention is involved.

If the polypeptide of the invention has an enzymatic activity,regardless as to whether it is a secretory protein, membrane protein, orproteins involved in signal transduction, glycoprotein, transcription,or diseases, a screening may be performed by adding a compound to thepolypeptide of the invention and monitoring the change of the compound.The enzymatic activity may also be utilized to screen a compound thatcan inhibit the activity of the polypeptide.

In a screening given as an example, the polypeptide of the invention isexpressed and the recombinant polypeptide is purified. Then, compoundsare contacted with the purified polypeptide, and the amount of thecompound and the reaction products is examined. Alternatively, compoundsthat are candidates of an inhibitor are pretreated, then a compound(substrate) that can react with the purified polypeptide is added, andthe amount of the substrate and the reaction products is examined.

The compounds obtained in the screening may be used as a medicine fordiseases in which the polypeptide of the invention is involved. Alsothey can be applied for tests that examine whether the polypeptide ofthe invention functions normally in vivo.

Whether the secretory protein, membrane protein, signaltransduction-related protein, glycoprotein-related protein, ortranscription-related protein of the present invention is a novelprotein involved in diseases or not is determined in another method thandescribed above, by obtaining a specific antibody against thepolypeptide of the invention, and examining the relationship between theexpression or activity of the polypeptide and a certain disease. In analternative way, it may be analyzed referred to the methods in“Molecular Diagnosis of Genetic Diseases” (Elles R. edit, (1996) in theseries of “Method in Molecular Biology” (Humana Press).

Proteins involved in diseases are targets of screening as mentioned, andthus are very useful in developing drugs which regulate their expressionand activity. Also, the proteins are useful in the medicinal industry asa diagnostic marker of the related disease or a target of gene therapy.

Compounds isolated as mentioned above can be administered patients as itis, or after formulated into a pharmaceutical composition according tothe known methods. For example, a pharmaceutically acceptable carrier orvehicle, specifically sterilized water, saline, plant oil, emulsifier,or suspending agent can be mixed with the compounds appropriately. Thepharmaceutical compositions can be administered to patients by a methodknown to those skilled in the art, such as intraarterial, intravenous,or subcutaneous injections. The dosage may vary depending on the weightor age of a patient, or the method of administration, but those skilledin the art can choose an appropriate dosage properly. If the compound isencoded by polynucleotide, the polynucleotide can be cloned into avector for gene therapy, and used for gene therapy. The dosage of thepolynucleotide and the method of its administration may vary dependingon the weight or age of a patient, or the symptoms, but those skilled inthe art can choose properly.

The present invention further relates to databases comprising at least asequence of polynucleotide and/or polypeptide, or a medium recorded insuch databases, selected from the sequence data of the nucleotide and/orthe amino acids indicated in Table 1. The term “database” means a set ofaccumulated information as machine-searchable and readable informationof nucleotide sequence. The databases of the present invention compriseat least one of the novel nucleotide sequences of polynucleotidesprovided by the present invention. The databases of the presentinvention can consist of only the sequence data of the novelpolynucleotides provided by the present invention or can comprise otherinformation on nucleotide sequences of known full-length cDNAs or ESTs.The databases of the present invention can be comprised of not only theinformation on the nucleotide sequences but also the information on thegene functions revealed by the present invention. Additional informationsuch as names of DNA clones carrying the full-length cDNAs can berecorded or linked together with the sequence data in the databases.

The database of the present invention is useful for gaining completegene sequence information from partial sequence information of a gene ofinterest. The database of the present invention comprises nucleotidesequence information of full-length cDNAs. Consequently, by comparingthe information in this database with the nucleotide sequence of apartial gene fragment yielded by differential display method orsubtraction method, the information on the full-length nucleotidesequence of interest can be gained from the sequence of the partialfragment as a starting clue.

The sequence information of the full-length cDNAs constituting thedatabase of the present invention contains not only the information onthe complete sequences but also extra information on expressionfrequency of the genes as well as homology of the genes to known genesand known polypeptides. Thus the extra information facilitates rapidfunctional analyses of partial gene fragments. Further, the informationon human genes is accumulated in the database of the present invention,and therefore, the database is useful for isolating a human homologue ofa gene originating from other species. The human homologue can beisolated based on the nucleotide sequence of the gene from the originalspecies.

At present, information on a wide variety of gene fragments can beobtained by differential display method and subtraction method. Ingeneral, these gene fragments are utilized as tools for isolating thefull-length sequences thereof. When the gene fragment corresponds to analready-known gene, the full-length sequence is easily obtained bycomparing the partial sequence with the information in known databases.However, when there exists no information corresponding to the partialsequence of interest in the known databases, cDNA cloning should becarried out for the full-length cDNA. It is often difficult to obtainthe full-length nucleotide sequence using the partial sequenceinformation as an initial clue. If the full-length of the gene is notavailable, the amino acid sequence of the polypeptide encoded by thegene remains unidentified. Thus the database of the present inventioncan contribute to the identification of full-length cDNAs correspondingto gene fragments, which cannot be revealed by using databases of knowngenes.

The present invention has provided 1970 polynucleotides. As has not yetproceeded the isolation of full-length cDNA within the human, theinvention has great significance. It is known that secretory proteins,membrane proteins, signal transduction-related proteins,glycoprotein-related proteins, transcription-related proteins, and so onare involved in many diseases. The genes and proteins involved indiseases are useful for developing a diagnostic marker or medicines forregulation of their expression and activity, or as a target of genetherapy.

In particular, cDNA assumed to encode secretory proteins, which wereprovided by this invention, are very important for the industry sincethe encoded proteins themselves are expected to be useful aspharmaceutical agents and many disease-related genes may be included inthem. In addition, membrane proteins, signal transduction-relatedproteins, transcription-related proteins, disease-related proteins, andgenes encoding them can be used as indicators for diseases, etc. ThesecDNA are also very important for the industry, which are expected toregulate the activity or expression of the encoded protein to treatdiseases, etc.

Any patents, patent applications, and publications cited herein areincorporated by reference.

The invention is illustrated more specifically with reference to thefollowing examples, but is not to be construed as being limited thereto.

EXAMPLE 1 Preparation of cDNA Library by Oligo-Capping

(1) Extraction and Purchase of mRNA

Total RNAs as mRNA sources were extracted from human tissues (shownbelow) by the method as described in the reference (J. Sambrook, E. F.Fritsch & T. Maniatis, Molecular Cloning Second edition, Cold Springharbor Laboratory Press, 1989). Further, by the method as described inthe reference (J. Sambrook, E. F. Fritsch & T. Maniatis, MolecularCloning Second edition, Cold Spring harbor Laboratory Press, 1989),total RNAs as mRNA sources were extracted from human culture cells andhuman primary culture cells (shown below) which had been cultivated bythe methods described in the catalogs.

The library names and the origins are indicated below in the order of“Library name: Origin”. When a library was prepared by the subtractionmethod, the item is followed by a description of how to prepare thesubtracted library.

<Extraction of mRNA from Human Tissues>

-   NTONG: Normal tongue;-   CTONG: Tongue cancer;-   FCBBF: Fetal brain;-   OCBBF: Fetal brain;-   PLACE: Placenta;-   SYNOV: Synovial membrane tissue (from rheumatioid arthritis).    <Extraction of mRNA from Culture Cells>-   BNGH4: H4 cells (ATCC #HTB-148);-   IMR32: IMR32 cells (ATCC #CCL-127);-   SKNMC: SK-N-MC cells (ATCC #HTB-10);-   3NB69: NB69 cells (RCB #RCB0480);-   BGGI1: GI1 cells (RCB #RCB0763);-   NB9N4: NB9 cells (RCB #RCB0477);-   SKNSH: SK-N-SH cells (RCB #RCB0426);-   NT2RM: NT2 cells (STARATAGENE #204101);-   NT2RP: NT2 cells treated with retinoic acid (RA) for 5 weeks to    induce the differentiation;-   NT2R1: NT2 cells treated with RA for 5 weeks to induce the    differentiation, followed by the treatment with the growth inhibitor    for 2 weeks;-   NT2NE: NT2 cells were treated with RA and the growth inhibitor for    the neuronal differentiation, and the resultant neurons were    concentrated and harvested (NT2 Neuron);-   NTISM: NT2 cells (STARATAGENE #204101) were treated with RA for 5    weeks to induce the differentiation, and then treated with the    growth inhibitor for 2 weeks; mRNA was prepared from the cells and a    cDNA library was constructed from the mRNA; the cDNAs of the library    whose nucleotide sequences were shared by those of mRNAs from    undifferentiated NT2 cells were subtracted by using a Subtract Kit    (Invitrogen #K4320-01); the subtracted library (NT2R1-NT2RM) was    provided by this procedure.

RCB indicates that the cell was provided by the Cell Bank, RIKEN GENEBANK, The Institute of Physical and Chemical Research; ATCC indicatesthat the cell was provided by American Type Culture Collection.

<Extraction of mRNA from Primary Culture Cells>

-   ASTRO: Normal human astrocyte NHA5732, Takara Shuzo #CC2565;-   DFNES: Normal human dermal fibroblast (neonatal skin); NHDF-Neo    NHDF2564, Takara Shuzo #CC2509;-   MESAN: Normal human mesangial cell NHMC56046-2, Takara Shuzo    #CC2559;-   NHNPC: Normal human neural progenitor cell NHNP5958, Takara Shuzo    #CC2599;-   PEBLM: Normal human peripheral blood mononuclear cell HPBMC5939,    Takara Shuzo #CC2702;-   HSYRA: Human synoviocyte HS-RA (from rheumatioid arthritis), Toyobo    #T404K-05;-   PUAEN: Normal human pulmonary artery endothelial cells, Toyobo    #T302K-05;-   UMVEN: Normal human umbilical vein endothelial cell HUVEC, Toyobo    #T200K-05;-   HCASM: Normal human coronary artery smooth muscle cell HCASMC,    Toyobo #T305K-05;-   HCHON: Normal human chondrocyte HC, Toyobo #T402K-05;-   HHDPC: Normal human dermal papilla cell HDPC, Toyobo #THPCK-001;-   CD34C: CD34+ cells (AllCells, LLC #CB14435M);-   D30ST: CD34+ cells treated with the osteoclast differentiation    factor (ODF) for 3 days to induce the differentiation;-   D60ST: CD34+ cells treated with ODF for 6 days to induce the    differentiation;-   D90ST: CD34+ cells treated with ODF for 9 days to induce the    differentiation.

Then, total RNAs extracted from the following human tissues werepurchased and used as mRNA sources. The library names and the originsare indicated below in the order of “Library name: Origin”. When alibrary was prepared by the subtraction method, the item is followed bya description of how to prepare the subtracted library.

<Purchase of Total RNA Containing mRNA Extracted from Human Tissues>

-   ADRGL: Adrenal gland, CLONTECH #64016-1;-   BRACE: Brain (cerebellum), CLONTECH #64035-1;-   BRAWH: Whole brain, CLONTECH #64020-1;-   FEBRA: Fetal brain, CLONTECH #64019-1;-   FELIV: Fetal liver, CLONTECH #64018-1;-   HEART: Heart, CLONTECH #64025-1;-   HLUNG: Lung, CLONTECH #64023-1;-   KIDNE: Kidney, CLONTECH #64030-1;-   LIVER: Liver, CLONTECH #64022-1;-   MAMGL: Mammary Gland, CLONTECH #64037-1;-   PANCR: Pancreas, CLONTECH #64031-1;-   PROST: Prostate, CLONTECH #64038-1;-   SALGL: Salivary Gland, CLONTECH #64026-1;-   SKMUS: Skeletal Muscle, CLONTECH #64033-1;-   SMINT: Small Intestine, CLONTECH #64039-1;-   SPLEN: Spleen, CLONTECH #64034-1;-   STOMA: Stomach, CLONTECH #64090-1;-   TBAES: Breast (Tumor), CLONTECH #64015-1;-   TCERX: Cervix (Tumor), CLONTECH #64010-1;-   TCOLN: Colon (Tumor), CLONTECH #64014-1;-   TESTI: Testis, CLONTECH #64027-1;-   THYMU: Thymus, CLONTECH #64028-1;-   TLUNG: Lung (Tumor), CLONTECH #64013-1;-   TOVAR: Ovary (Tumor), CLONTECH #64011-1;-   TRACH: Trachea, CLONTECH #64091-1;-   TUTER: Uterus (Tumor), CLONTECH #64008-1;-   UTERU: Uterus, CLONTECH #64029-1;-   ADIPS: Adipose, Invitrogen #D6005-01;-   BLADE: Bladder, Invitrogen #D6020-01;-   BRALZ: Cerebral cortex from an Alzheimer patient (Brain, cortex,    Alzheimer), Invitrogen #D6830-01;-   CERVX: Cervix, Invitrogen #D6047-01;-   COLON: Colon, Invitrogen #D6050-0;-   NESOP: Esophagus, Invitrogen #D6060-01;-   PERIC: Pericardium, Invitrogen #D6105-01;-   RECTM: Rectum, Invitrogen #D6110-01;-   TESOP: Esophageal (Tumor), Invitrogen #D6860-01;-   TKIDN: Kidney (Tumor), Invitrogen #D6870-01;-   TLIVE: Liver (Tumor), Invitrogen #D6880-01;-   TSTOM: Stomach (Tumor), Invitrogen #D6920-01;-   BEAST: Adult breast, STARATAGENE #735044;-   FEHRT: Fetal heart, STARATAGENE #738012;-   FEKID: Fetal kidney, STARATAGENE #738014;-   FELNG: Fetal lung, STARATAGENE #738020;-   NOVAR: Adult ovary, STARATAGENE #735260;-   BRASW: subtracted library (BRALZ-BRAWH). A cDNA library was    constructed from mRNA prepared from tissues of cerebral cortex    obtained from an Alzheimer patient [BRALZ: Cerebral cortex from an    Alzheimer patient (Brain, cortex, Alzheimer), Invitrogen #D6830-01];    the cDNAs of this library whose nucleotide sequences were shared by    those of mRNAs from whole brain tissue [BRAWH: Whole brain, CLONTECH    #64020-1] were subtracted by using a Subtract Kit (Invitrogen    #K4320-01).

Further, mRNAs extracted and purified as poly A(+) RNAs from the humantissues shown below were purchased. A cDNA library was prepared from anRNA mixture in which the poly A(+) RNA from each tissue had beencombined with poly A(−) RNA. The poly A(−) RNA was prepared by removingpoly A(+) RNA from the total RNA of whole brain tissue (CLONTECH#64020-1) by using oligo dT cellulose. The library names and the originsare indicated below in the order of “Library name: Origin”.

<Purchase of mRNAs of Human Tissues as Poly A(+) RNAs>

-   BRAMY: Brain (amygdala), CLONTECH #6574-1;-   BRCAN: Brain (caudate nucleus), CLONTECH #6575-1;-   BRCOC: Brain (corpus callosum), CLONTECH #6577-1;-   BRHIP: Brain (hippocampus), CLONTECH #6578-1;-   BRSSN: Brain (substantia nigra), CLONTECH #6580-1;-   BRSTN: Brain (subthalamic nucleus), CLONTECH #6581-1;-   BRTHA: Brain (thalamus), CLONTECH #6582-1.    (2) Preparation of cDNA Library

cDNA library was prepared from each RNA by the improved method (WO01/04286) of oligo capping [M. Maruyama and S. Sugano, Gene, 138:171-174 (1994)]. A series of procedures, BAP (Bacterial AlkalinePhosphatase) treatment, TAP (Tobacco Acid Pyrophosphatase) treatment,RNA ligation, first strand cDNA synthesis and RNA removal, were carriedout using the oligo-cap linker (SEQ ID NO: 4093) and oligo dT primer(SEQ ID NO: 4094), as described in WO 01/04286. Then, thesingle-stranded cDNA was converted to a double-stranded cDNA by PCR(polymerase chain reaction) using 5′ (SEQ ID NO: 4095) and 3′ (SEQ IDNO: 4096) PCR primers, and then digested with SfiI. Then, a fraction ofcDNA fragments, typically 2-kb or longer (3-kb or longer in some cases),was unidirectionally cloned into a DraIII-digested pME18SFL3 vector(FIG. 1) (GenBank AB009864, Expression vector); the cDNA library wasthus prepared.

The names of cDNA libraries, which were used in the analysis offull-length cDNA sequences, and their origins are shown in Table 2.TABLE 2 Library Type Origin, etc. ADRGL Tissue Adrenal gland (CLONTECH#64016-1) ASTRO Primary Normal Human Astrocyte NHA5732 (Takara Shuzo#CC2565) culture cell BGGI1 Culture cell GI1 cells (RCB #RCB0763) BNGH4Culture cell H4 cells (ATCC #HTB-148) BRACE Tissue Brain, cerebellum(CLONTECH #64035-1) BRAMY Tissue Brain, amygdala (CLONTECH #6574-1)BRAWH Tissue Brain, whole (CLONTECH #64020-1) BRCAN Tissue Brain,caudate nucleus (CLONTECH #6575-1) BRCOC Tissue Brain, corpus callosum(CLONTECH #6577-1) BRHIP Tissue Brain, hippocampus (CLONTECH #6578-1)BRSSN Tissue Brain, substantia nigra (CLONTECH #6580-1) CD34C PrimaryCD34+ cells (AllCells, LLC #CB14435M) culture cell CTONG Tissue Tongue,Cancer DFNES Primary Normal Human Dermal Fibroblasts (Neonatal Skin):NHDF-Neo culture cell NHDF2564 (Takara Shuzo #CC2509) FCBBF TissueBrain, Fetal FEBRA Tissue Brain, Fetal (CLONTECH #64019-1) HCHON PrimaryHuman Chondrocytes HC (Toyobo #T402K-05) culture cell HEART Tissue Heart(CLONTECH #64025-1) HHDPC Primary Human dermal papilla cells HDPC(Toyobo #THPCK-001) culture cell HLUNG Tissue Lung (CLONTECH #64023-1)KIDNE Tissue Kidney (CLONTECH #64030-1) LIVER Tissue Liver (CLONTECH#64022-1) MESAN Primary Normal human mesangial cells NHMC56046-2 (TakaraShuzo culture cell #CC2559) NESOP Tissue Esophagus (Invitrogen#D6060-01) NT2NE Culture cell NT2 cells concentrated afterdifferentiation (NT2 Neuron) NT2RI Culture cell NT2 cells treated bygrowth inhibitor for 2 weeks after RA induction for 5 weeks NT2RPCulture cell NT2 cells treated by RA for 5 weeks NTONG Tissue TongueOCBBF Tissue Brain, Fetal PANCR Tissue Pancreas (CLONTECH #64031-1)PEBLM Primary Human peripheral blood mononuclear cells HPBMC5939 culturecell (Takara Shuzo #CC2102) PLACE Tissue Placenta PROST Tissue Prostate(CLONTECH #64038-1) PUAEN Primary Human pulmonary artery endothelialcells (Toyobo #T302K-05) culture cell SALGL Tissue Salivary Gland(CLONTECH #64026-1) SKMUS Tissue Skeletal Muscle (CLONTECH #64033-1)SKNMC Culture cell SK-N-MC cells (ATCC #HTB-10) SKNSH Culture cellSK-N-SH cells (RCB #RCB0426) SMINT Tissue Small Intestine (CLONTECH#64039-1) SPLEN Tissue Spleen (CLONTECH #64034-1) TESOP TissueEsophageal, Tumor (Invitrogen #D6860-01) TESTI Tissue Testis (CLONTECH#64027-1) THYMU Tissue Thymus (CLONTECH #64028-1) TKIDN Tissue Kidney,Tumor (Invitrogen #D6870-01) TRACH Tissue Trachea (CLONTECH #64091-1)UMVEN Primary Human umbilical vein endothelial cells HUVEC (Toyoboculture cell #T200K-05) UTERU Tissue Uterus (CLONTECH #64029-1)

The cDNA library with the high fullness ratio (the fullness ratio of5′-end, which was calculated for each cDNA library by using the proteincoding region found in known mRNA species as an index, was 90% inaverage) prepared by the improved oligo-capping method was constructedby using a eukaryotic expression vector pME18SFL3. The vector containsSRα promoter and SV40 small t intron in the upstream of the cloningsite, and SV40 polyA added signal sequence site in the downstream. Asthe cloning site of pME18SFL3 has asymmetrical DraIII sites, and theends of cDNA fragments contain SfiI sites complementary to the DraIIIsites, the cloned cDNA fragments can be inserted into the downstream ofthe SRα promoter unidirectionally. Therefore, clones containingfull-length cDNA can be expressed transiently by introducing theobtained plasmid directly into COS cells, etc. Thus, the clones can beanalyzed very easily in terms of the proteins that are the gene productsof the clones, or in terms of the biological activities of the proteins.

(3) Assessment of the 5′-end Completeness of Clones Derived from thecDNA Library Prepared by Oligo-Capping

With respect to the plasmid DNAs of clones derived from the libraries,the nucleotide sequences of cDNA 5′-ends (3′-ends as well in some cases)were determined in a DNA sequencer (ABI PRISM 3700, PE Biosystems),after sequencing reaction was conducted by using a DNA sequencingreagent (BigDye Terminator Cycle Sequencing FS Ready Reaction Kit, PEBiosystems) according to the manual. A database was constructed based onthe obtained data.

The 5′-end completeness of about 770,000 clones derived from the humancDNA libraries prepared by the improved oligo-capping method wasdetermined by the following method. The clones whose 5′-end sequenceswere consistent with those of known human mRNA in the public databasewere judged to be “full-length” if they had a longer 5′-end sequencethan that of the known human mRNA; or even though the 5′-end sequencewas shorter, if it contained the translation initiation codon it wasjudged to have the “full-length” sequence. Clones which did not containthe translation initiation codon were judged to be “not-full-length”.The fullness ratio ((the number of full-length clones)/(the number offull-length and not-full-length clones)) at the 5′-end of the cDNAclones was determined by comparing with known human mRNA. As a result,the fullness ratio of the 5′-ends was 90%. The result indicates that thefullness ratio at the 5′-end sequence was extremely high in the humancDNA clones obtained by the oligo-capping method.

EXAMPLE 2 Sequencing Analysis of cDNA Ends and Selection of Full-LengthClones

With respect to the plasmid DNAs of clones obtained from each cDNAlibrary, the 5′-end nucleotide sequences of the cDNAs were determined ina DNA sequencer (ABI PRISM 3700, PE Biosystems), after sequencingreaction was conducted by using a DNA sequencing reagent (Dye TerminatorCycle Sequencing FS Ready Reaction Kit, dRhodamine Terminator CycleSequencing FS Ready Reaction Kit or BigDye Terminator Cycle SequencingFS Ready Reaction Kit, PE Biosystems) according to the manual. Adatabase was constructed using the data obtained.

For the analyzed 5′-end sequences of cDNA clones, the data with theannotation of “complete cds” in the GenBank and UniGene were searched byBLAST homology search. When identical to certain human mRNA sequences,such cDNA clones were excluded. Then, clustering was carried out. Whenthe identity was 90% or higher, and the length of consensus sequence was50 base pairs or longer, the cDNA clones were assumed to belong to anidentical cluster, and thus clustered. cDNA clones longer in the 5′direction were selected from the members belonging to a cluster; ifrequired, the 31-end sequences of the selected clones were determined bythe same analysis method as used to determine the 5′-end sequences. Thedata of the end sequences obtained were analyzed, and then the clonesforming a sequence contig at 5′- and 3′-ends were excluded. Further, asmentioned above, the data was analyzed again by BLAST homology search;when identical to certain human mRNA sequences (including sequencespatented and applied for), the cDNA clones were excluded. Thus, thecDNAs clones to be analyzed for their nucleotide sequence were obtained.

EXAMPLE 3 Analysis of the Full-Length Nucleotide Sequences

The full-length nucleotide sequences of the selected clones weredetermined. The nucleotide sequence determination was mainly performedby primer walking method comprising the dideoxy terminator method usingcustom-made synthetic DNA primers. Namely, the nucleotide sequences ofthe DNAs were determined in a sequencer from PE Biosystems, aftersequencing reaction was carried out with a DNA sequencing reagent fromthe same supplier using the custom-made synthetic DNA primers accordingto the manual. A part of the clones were analyzed with a DNA sequencerfrom Licor.

Further, the nucleotide sequences of a part of the clones weredetermined by the shotgun method where the plasmids containing the cDNAswere digested at random were used, instead of the use of custom-madeprimers, by the same method in the DNA sequencer. The full-lengthnucleotide sequences were finally determined by completely assemblingthe partial nucleotide sequences obtained by the above method.

Then, the regions translatable to proteins were deduced from thedetermined full-length nucleotide sequences, and thereby the amino acidsequences were determined. SEQ ID NOs corresponding to the respectivesequences are shown in Table 1.

EXAMPLE 4 Functional Prediction by Homology Search

For the determined nucleotide sequences, GenBank, SwissProt, UniGene,and nr were searched by BLAST. The clones exhibiting higher homology,which were convenient to predict their functions based on the nucleotidesequences and deduced amino acid sequences, were selected based on theBLAST search hit data whose P value or E value was 10⁻⁴ or lower and forwhich the length of consensus sequence×homology=30 or higher in theamino acid database search. Further, from them, representative cloneswere selected, which are shown as Homology Search Result Data in thelast part herein. Accordingly, the data shown herein are merely therepresentative data, and the molecule exhibiting homology to each cloneis not limited thereto. Further, with respect to a part of clones, theBLAST search hit data that did not meet the criteria as described aboveare not shown herein.

EXAMPLE 5 Search for Signal Sequence, Transmembrane Domain and OtherFunctional Domains in the Deduced Amino Acid Sequences

With respect to the amino acid sequences deduced from the full-lengthnucleotide sequences, the prediction was made for the presence of signalsequence at the amino terminus, the presence of transmembrane domain,and the presence of functional protein domains (motifs). The signalsequence at the amino terminus was searched for by PSORT [K. Nakai & M.Kanehisa, Genomics, 14: 897-911 (1992)]; the transmembrane domain, bySOSUI [T. Hirokawa et al., Bioinformatics, 14: 378-379 (1998)] (MitsuiKnowledge Industry); the function domain, by Pfam(http://www.sanger.ac.uk/Software/Pfam/index.shtml). The amino acidsequence in which the signal sequence at the amino terminus ortransmembrane domain had been predicted to be present by PSORT or SOSUIwere assumed to be a secretory or membrane protein. Further, when theamino acid sequence hit a certain functional domain by the Pfamfunctional domain search, the protein function can be predicted based onthe hit data, for example, by referring to the function categories onthe PROSITE (http://www.expasy.ch/cgi-bin/prosite-list.pl). In addition,the functional domain search can also be carried out on the PROSITE.

The search results obtained with the respective programs are shownbelow.

The clones whose deduced amino acid sequences were detected to have thesignal sequences by PSORT are as follows. ADRGL20021910, ADRGL20036380,ADRGL20063770, ASTRO20020240, BNGH420052350, BNGH420077980,BRACE20054080, BRACE20194670, BRAMY20044920, BRAMY20047560,BRAMY20137360, BRAMY20204270, BRAMY20237190, BRAMY20251750,BRAWH20020470, BRAWH20093070, BRCAN10001680, BRHIP10000720,BRSSN20091190, CD34C20001750, CTONG20059130, CTONG20069320,FCBBF30062490, FCBBF30132660, FEBRA20039260, FEBRA20040230,FEBRA20040560, FEBRA20046280, FEBRA20182030, HCHON10001660,HCHON20015050, HEART10001490, HHDPC20088160, HLUNG20032460,HLUNG20034970, HLUNG20050760, HLUNG20081390, HLUNG20088750,KIDNE20134130, KIDNE20143200, LIVER20007750, LIVER20010510,MESAN20021220, MESAN20027900, MESAN20095220, NT2NE20069580,NT2NE20082130, NT2NE20167660, NT2RP70003110, OCBBF20000740,OCBBF20012520, OCBBF20110730, OCBBF20118720, OCBBF20155030,OCBBF20170350, OCBBF20191950, PANCR10000860, PEBLM20001800,PLACE60004260, PLACE60006300, PLACE60055590, PLACE60056910,PLACE60057860, PLACE60104630, PLACE60184870, PROST20050390,PROST20084680, PROST20105450, PROST20106060, PR0ST20110120,SKMUS20091900, SKNMC20006350, SMINT20024140, SMINT20028840,SMINT20086250, SMINT20088440, SMINT20088690, SPLEN20017810,SPLEN20073880, SPLEN20080070, SPLEN20101950, SPLEN20108000,SPLEN20110860, SPLEN20118050, SPLEN20138600, SPLEN20139100,SPLEN20193230, SPLEN20193490, SPLEN20201830, TESTI20043130,TESTI20047370, TESTI20057200, TESTI20059080, TESTI20061200,TESTI20063330, TESTI20063600, TESTI20102390, TESTI20116120,TESTI20151800, TESTI20166670, TESTI20210030, TESTI20245860,THYMU20020800, THYMU20046770, THYMU20050010, THYMU20054800,THYMU20055740, THYMU20083390, THYMU20115380, TRACH20081270,TRACH20159390, UTERU20040150, UTERU20064120, UTERU20086530,UTERU20127150

The clones whose deduced amino acid sequences were detected to have thetransmembrane domains by SOSUI are as follows. Numerals indicate thenumbers of transmembrane domains detected in the deduced amino acidsequences. Of the search result, the clone name and the number oftransmembrane domains are demarcated by a double slash mark (//).ADRGL20020290//10, ADRGL20021910//2, ADRGL20063770//2, ASTRO20010010//4,ASTRO20045840//3, ASTRO20053430//1, ASTRO20055530//1, ASTRO20055570//2,ASTRO20055930//2, ASTRO20075150//1, ASTRO20088950//1, ASTRO20091180//4,BNGH420021680//1, BNGH420023870//1, BNGH420052350//1, BNGH420059680//1,BNGH420075940//1, BNGH420087430//3, BRACE10000510//2, BRACE20052530//1,BRACE20066360//3, BRACE20068710//1, BRACE20069000//5, BRACE20069110//1,BRAMY10001730//1, BRAMY20001510//1, BRAMY20003880//1, BRAMY20024790//2,BRAMY20027390//2, BRAMY20028530//2, BRAMY20035380//2, BRAMY20045210//1,BRAMY20050940//3, BRAMY20053910//2, BRAMY20055760//5, BRAMY20072440//8,BRAMY20083820//2, BRAMY20089770//1, BRAMY20096930//1, BRAMY20118410//1,BRAMY20123400//2, BRAMY20125550//1, BRAMY20127310//1, BRAMY20127760//1,BRAMY20135720//3, BRAMY20139440//5, BRAMY20152510//1, BRAMY20194680//2,BRAMY20204270//1, BRAMY20225320//2, BRAMY20237190//1, BRAMY20251750//1,BRAMY20285650//2, BRAWH20020470//7, BRAWH20026010//1, BRAWH20030000//2,BRAWH20039640//2, BRAWH20055330//1, BRAWH20078620//2, BRAWH20093040//3,BRAWH20185270//5, BRAWH20190550//1, BRCAN10000760//10, BRCAN20001480//3,BRCAN20004180//1, BRCOC20000470//2, BRCOC20003600//1, BRHIP10001040//5,BRHIP20000210//1, BRSSN20001970//4, BRSSN20074640//2, CD34C20001750//1,CTONG20017490//1, CTONG20029030//4, CTONG20041260//9, CTONG20044870//2,CTONG20045500//2, CTONG20049480//3, CTONG20051450//1, CTONG20056150//2,CTONG20059130//6, CTONG20060040//1, CTONG20065680//1, CTONG20071680//13,CTONG20076810//1, CTONG20078340//2, CTONG20079590//1, CTONG20083980//1,CTONG20084020//2, CTONG20167750//1, CTONG20168240//3, CTONG20179890//5,CTONG20183830//1, DFNES20018000//2, DFNES20028170//1, DFNES20029660//8,DFNES20072990//9, DFNES20080880//1, FCBBF20018680//3, FCBBF20029280//2,FCBBF20032930//1, FCBBF20036360//2, FCBBF20054390//2, FCBBF30022680//1,FCBBF30042610//7, FCBBF30062490//2, FCBBF30075970//1, FCBBF30078600//3,FCBBF30095410//1, FCBBF30105440//3, FCBBF30118670//1, FCBBF30145670//1,FCBBF30164510//1, FCBBF30169870//1, FCBBF30172330//1, FCBBF30177290//2,FCBBF30179740//1, FCBBF30195690//2, FCBBF30197840//1, FCBBF30212210//1,FCBBF30223110//1, FCBBF30225930//9, FCBBF30230610//1, FCBBF30260480//5,FCBBF30266510//3, FCBBF30287940//1, FCBBF50000610//2, FCBBF50004950//3,FEBRA20007820//4, FEBRA20018670//2, FEBRA20031280//7, FEBRA20031810//2,FEBRA20040560//4, FEBRA20057010//1, FEBRA20080860//1, FEBRA20084750//1,FEBRA20115930//10, FEBRA20116650//4, FEBRA20121950//5, FEBRA20141980//1,FEBRA20177800//1, FEBRA20182030//1, HCHON20015050//1, HEART20031680//1,HHDPC10001140//1, HHDPC20051850//1, HHDPC20082790//3, HHDPC20088160//1,HLUNG20015070//2, HLUNG20020850//2, HLUNG20029490//1, HLUNG20032460//1,HLUNG20033350//2, HLUNG20037160//2, HLUNG20050760//1, HLUNG20052300//1,HLUNG20060670//1, HLUNG20065990//1, HLUNG20074330//1, HLUNG20081390//2,HLUNG20092530//1, KIDNE20016360//5, KIDNE20083150//3, KIDNE20084030//12,KIDNE20084800//2, KIDNE20086490//1, KIDNE20086660//2, KIDNE20094670//1,KIDNE20142900//1, KIDNE20148080//1, KIDNE20160960//2, KIDNE20163710//1,KIDNE20169180//2, KIDNE20182540//3, KIDNE20186170//1, KIDNE20188630//1,KIDNE20189960//1, LIVER20007750//8, LIVER20010990//4, LIVER20030650//6,LIVER20038000//4, MESAN20007110//1, MESAN20008150//3, MESAN20021220//2,MESAN20060430//1, MESAN20067430//3, MESAN20084150//3, NT2NE20018740//1,NT2NE20039210//1, NT2NE20053230//1, NT2NE20059210//1, NT2NE20080770//1,NT2NE20082130//3, NT2NE20092950//1, NT2NE20152620//1, NT2NE20167660//1,NT2NE20181800//1, NT2RI20016240//2, NT2RI20021200//3, NT2RI20033920//5,NT2RP70027790//2, NT2RP70031070//10, NT2RP70031480//6, NT2RP70087140//1,OCBBF20000740//2, OCBBF20012520//2, OCBBF20109780//1, OCBBF20110210//2,OCBBF20110730//2, OCBBF20112280//3, OCBBF20118720//3, OCBBF20123200//2,OCBBF20165910//9, OCBBF20176650//1, OCBBF20185630//1, OCBBF20191950//3,PANCR10000860//1, PLACE60004260//1, PLACE60006300//2, PLACE60053280//3,PLACE60056910//1, PLACE60057860//3, PLACE60061370//1, PLACE60070500//2,PLACE60104630//3, PLACE60107010//2, PLACE60184870//1, PROST20011160//2,PROST20014150//2, PROST20035830//1, PROST20050390//1, PROST20065100//7,PROST20073280//1, PROST20082430//1, PROST20084680//3, PROST20105450//6,PROST20110120//1, PROST20114100//2, PROST20152510//4, PROST20168600//6,PUAEN10000870//2, SKMUS20006790//1, SKMUS20020770//1, SKNMC20006350//1,SKNSH20094350//2, SMINT20008110//3, SMINT20024140//1, SMINT20026200//1,SMINT20028840//1, SMINT20045470//1, SMINT20081330//2, SMINT20092160//1,SPLEN20015100//2, SPLEN20017610//1, SPLEN20017810//2, SPLEN20024620//2,SPLEN20054500//1, SPLEN20058180//1, SPLEN20085910//2, SPLEN20090880//2,SPLEN20101950//5, SPLEN20104690//1, SPLEN20105100//2, SPLEN20110180//1,SPLEN20121790//1, SPLEN20125230//1, SPLEN20136700//1, SPLEN20175920//1,SPLEN20177400//2, SPLEN20182850//1, SPLEN20183950//1, SPLEN20190080//1,SPLEN20190770//1, SPLEN20193230//1, SPLEN20193790//1, SPLEN20204670//1,TESOP10000350//1, TESTI20006160//5, TESTI20038240//1, TESTI20043220//1,TESTI20046540//1, TESTI20046870//1, TESTI20050400//1, TESTI20051730//7,TESTI20053260//2, TESTI20053780//1, TESTI20057200//1, TESTI20057590//1,TESTI20061200//10, TESTI20062120//1, TESTI20063330//1, TESTI20063410//1,TESTI20068530//2, TESTI20070400//10, TESTI20070740//1, TESTI20073460//1,TESTI20095200//6, TESTI20095880//10, TESTI20100090//1, TESTI20102390//2,TESTI20113940//3, TESTI20121040//1, TESTI20149880//3, TESTI20151800//3,TESTI20162780//4, TESTI20170170//1, TESTI20173050//1, TESTI20186110//11,TESTI20198540//2, TESTI20199110//1, TESTI20202830//1, TESTI20204260//1,TESTI20214630//2, TESTI20244730//1, TESTI20245860//1, TESTI20246410//1,TESTI20257910//1, TESTI20260640//1, TESTI20261040//4, TESTI20262150//11,TESTI20262940//1, TESTI20264910//1, TESTI20271790//9, TESTI20278280//3,TESTI20282420//2, TESTI20282900//1, TESTI20286590//1, THYMU20007020//3,THYMU20012020//1, THYMU20017270//2, THYMU20020800//4, THYMU20025480//3,THYMU20030690//7, THYMU20034790//2, THYMU20046350//1, THYMU20050010//5,THYMU20054800//2, THYMU20055740//1, THYMU20062770//1, THYMU20078240//1,THYMU20079690//2, THYMU20083390//3, THYMU20087270//1, THYMU20100940//4,THYMU20106990//1, THYMU20115380//2, THYMU20137050//3, THYMU20137570//1,THYMU20143230//2, THYMU20145990//3, THYMU20150190//2, THYMU20153210//10,THYMU20154790//3, THYMU20163600//2, THYMU20171580//1, THYMU20176010//1,THYMU20178440//1, THYMU20185470//2, TRACH20011540//2, TRACH20021380//4,TRACH20073990//1, TRACH20081270//2, TRACH20149720//1, TRACH20149740//1,TRACH20163470//11, TRACH20165330//3, TRACH20167090//2, TRACH20173680//8,UMVEN10001380//2, UTERU20035770//1, UTERU20045200//5, UTERU20064120//7,UTERU20086530//2, UTERU20089300//1, UTERU20095100//3, UTERU20099040//5,UTERU20103200//3, UTERU20125810//1, UTERU20127150//8, UTERU20139760//1,UTERU20188840//2

The Names of clones whose deduced amino acid sequences were detected tohave functional domains with Pfam, and the name of hit functionaldomains are as follows. The search result is indicated as “clonename//functional domain name”. When the clone has multiple hitfunctional domains, they are listed and demarcated by a double slashmark (//). When the clone has multiple hits of an identical functionaldomain, each is listed without abridgment.

-   ADRGL20020290//Sodium:galactoside symporter family//Nucleoside    transporter-   ADRGL20021910//Immunoglobulin domain-   ADRGL20026790//PWWP domain-   ADRGL20036840//Class I Histocompatibility antigen, domains alpha 1    and 2-   ADRGL20047770//ATP synthase (F/14-kDa) subunit-   ADRGL20059610//O-Glycosyl hydrolase family 30-   ADRGL20062330//Spectrin repeat//Spectrin repeat//Bacterial flagellin    N-terminus//Spectrin repeat//Spectrin repeat//Spectrin repeat-   ADRGL20066770//Collagen triple helix repeat (20 copies)//C1q domain-   ADRGL20079060//Transglutaminase-like superfamily-   ASTRO20006530//Intermediate filament proteins//Myc leucine zipper    domain-   ASTRO20010010//Photosynthetic reaction center protein-   ASTRO20010290//PHD-finger-   ASTRO20026320//Viral (Superfamily 1) RNA    helicase//Heavy-metal-associated domain//Viral (Superfamily 1) RNA    helicase-   ASTRO20038400//Homeobox domain//Common central domain of    tyrosinase//Rhabdovirus nucleocapsid protein//Homeobox    domain//Homeobox domain//Homeobox domain-   ASTRO20046280//MutT-like domain-   ASTRO20050810//FGGY family of carbohydrate kinases//FGGY family of    carbohydrate kinases-   ASTRO20052420//RhoGEF domain//PH domain//SH3 domain-   ASTRO20053430//FERM domain (Band 4.1 family)//FERM domain (Band 4.1    family)//Delta-aminolevulinic acid dehydratase//Lipoprotein amino    terminal region-   ASTRO20055570//Prion protein-   ASTRO20055930//Aldehyde oxidase and xanthine dehydrogenase, C    terminus//Zinc finger, C3HC4 type (RING finger)-   ASTRO20085080//WD domain, G-beta repeat//Fibrillarin//WD domain,    G-beta repeat//WD domain, G-beta repeat//WD domain, G-beta    repeat//WD domain, G-beta repeat//WD domain, G-beta repeat//WD    domain, G-beta repeat-   ASTRO20088950//Glycosyl hydrolase family 1-   BGGI120010750//Phosphoglucose isomerase//Ribosomal protein L7Ae-   BNGH420015760//WD domain, G-beta repeat//WD domain, G-beta    repeat//WD domain, G-beta repeat//WD domain, G-beta repeat//WD    domain, G-beta repeat-   BNGH420024870//C2 domain//C2 domain//C2 domain-   BNGH420035290//Zinc finger, C3HC4 type (RING finger)//TRAF-type zinc    finger//Hr1 repeat motif//WD domain, G-beta repeat//WD domain,    G-beta repeat//WD domain, G-beta repeat//WD domain, G-beta    repeat//WD domain, G-beta repeat//WD domain, G-beta repeat//WD    domain, G-beta repeat-   BNGH420036410//Arsenical pump membrane protein-   BNGH420046790//Immunoglobulin domain-   BNGH420052350//Urotensin II-   BNGH420059680//NHL repeat//NHL repeat//NHL repeat//NHL repeat-   BNGH420070370//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   BNGH420074600//RNA polymerase beta subunit-   BNGH420077980//Immunoglobulin domain//Immunoglobulin    domain//Immunoglobulin domain//Immunoglobulin domain//Immunoglobulin    domain//Immunoglobulin domain-   BNGH420086030//PH domain//RhoGAP domain-   BRACE20003310//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type-   BRACE20007330//BTB/POZ domain//Kelch motif//Kelch motif//Kelch    motif//Kelch motif//Kelch motif//Kelch motif-   BRACE20014450//alpha/beta hydrolase fold-   BRACE20050870//DEAD/DEAH box helicase-   BRACE20051600//Reverse transcriptase (RNA-dependent DNA polymerase)-   BRACE20051930//MAM domain.-   BRACE20054600//von Willebrand factor type D domain-   BRACE20055560//WD domain, G-beta repeat//WD domain, G-beta repeat-   BRACE20059810//TSC-22/dip/bun family-   BRACE20061620//SPRY domain-   BRACE20065470//Ubiquitin family-   BRACE20069000//CLN3 protein-   BRACE20079200//von Willebrand factor type D domain-   BRACE20099070//FYVE zinc finger-   BRACE20196180//HMG (high mobility group) box-   BRACE20204670//Protein-tyrosine phosphatase//Dual specificity    phosphatase, catalytic domain//Fatty acid    desaturase//Protein-tyrosine phosphatase-   BRACE20215410//Imidazoleglycerol-phosphate dehydratase//UvrD/REP    helicase-   BRAMY20001510//Zinc finger, C3HC4 type (RING finger)//PHD-finger-   BRAMY20003540//PH domain//EF hand//EF hand//Viral RNA dependent RNA    polymerase//Phosphatidylinositol-specific phospholipase C, X    domain//Phosphatidylinositol-specific phospholipase C, Y    domain//Bleomycin resistance protein//C2 domain-   BRAMY20005080//Ubiquitin carboxyl-terminal hydrolase family 2-   BRAMY20013670//S-adenosylmethionine synthetase-   BRAMY20016780//Proprotein convertase P-domain-   BRAMY20023640//UBX domain-   BRAMY20027990//C2 domain-   BRAMY20028620//Quinolinate phosphoribosyl transferase-   BRAMY20035380//Cation efflux family-   BRAMY20035830//BTB/POZ domain//Thymidylate synthase-   BRAMY20038980//Granulocyte-macrophage colony-stimulating    factor//Borrelia outer surface protein E and F-   BRAMY20040580//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   BRAMY20043630//Leucine Rich Repeat//Leucine Rich Repeat//Leucine    Rich Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat//Leucine Rich Repeat-   BRAMY20044920//Ubiquitin carboxyl-terminal hydrolase family 2-   BRAMY20045420//Domain found in Dishevelled, Egl-10, and Pleckstrin-   BRAMY20051820//C2 domain-   BRAMY20056620//Carboxyl transferase domain-   BRAMY20056840//PWWP domain-   BRAMY20076100//Ligand-binding domain of nuclear hormone receptor-   BRAMY20089770//ATP P2X receptor-   BRAMY20091230//Mitochondrial carrier proteins//Mitochondrial carrier    proteins-   BRAMY20094890//SURF4 family-   BRAMY20102900//Ephrin-   BRAMY20111780//Zinc finger, C2H2 type//Transcription factor S-II    (TFIIS)//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C3HC4 type (RING    finger)//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   BRAMY20117670//DnaJ central domain (4 repeats)//DnaJ C terminal    region-   BRAMY20118410//Phospholipase D. Active site motif-   BRAMY20118490//FGGY family of carbohydrate kinases-   BRAMY20125360//Asparaginase-   BRAMY20134050//Nucleosome assembly protein (NAP)-   BRAMY20143870//Peptidyl-tRNA hydrolase-   BRAMY20152510//Protein-tyrosine phosphatase//Dual specificity    phosphatase, catalytic domain-   BRAMY20158550//EF hand//EF hand-   BRAMY20206340//WD domain, G-beta repeat//Dockerin domain type I//WD    domain, G-beta repeat//WD domain, G-beta repeat//WD domain, G-beta    repeat//WD domain, G-beta repeat-   BRAMY20227860//Insulin-like growth factor binding proteins//Spectrin    repeat-   BRAMY20234820//Ribosomal L25p family-   BRAMY20238630//TPR Domain//TPR Domain//TPR Domain-   BRAMY20244490//Adenylate kinase-   BRAMY20245140//Cyclic nucleotide-binding domain-   BRAMY20251210//Ephrin receptor ligand binding domain//EB module-   BRAMY20263000//WD domain, G-beta repeat//WD domain, G-beta    repeat//WD domain, G-beta repeat//WD domain, G-beta repeat//WD    domain, G-beta repeat//WD domain, G-beta repeat-   BRAMY20274510//Ribosomal protein L11-   BRAWH20014590//RNA recognition motif. (a.k.a. RRM, RBD, or RNP    domain)-   BRAWH20021910//Carboxylesterases-   BRAWH20026010//Hepatitis C virus RNA dependent RNA polymerase-   BRAWH20039640//Leucine rich repeat N-terminal domain//Leucine Rich    Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine rich    repeat C-terminal domain//Leucine rich repeat N-terminal    domain//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat//Leucine rich repeat C-terminal domain-   BRAWH20040680//Zinc finger, C3HC4 type (RING finger)//DENN (AEX-3)    domain-   BRAWH20047790//HMG (high mobility group) box-   BRAWH20050740//BTB/POZ domain-   BRAWH20080580//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//DnaJ central domain (4    repeats)//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   BRAWH20093040//Eukaryotic protein kinase domain-   BRAWH20094900//BNR repeat//BNR repeat//BNR repeat-   BRAWH20095900//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Transcription factor S-II (TFIIS)//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//PHD-finger//Zinc finger, C2H2 type//Zinc finger, C2H2    type-   BRAWH20183170//Leucine Rich Repeat//Leucine Rich Repeat//Leucine    Rich Repeat//Leucine Rich Repeat-   BRAWH20185260//Troponin//Serine hydroxymethyltransferase-   BRAWH20185270//Uncharacterized protein family UPF0057-   BRAWH20188750//Glypican//ubiE/COQ5 methyltransferase family-   BRAWH20191980//Proline dehydrogenase-   BRCAN1001050//Cell division protein-   BRCAN20005410//Zinc finger, C4 type (two domains)//Zinc finger, C2HC    type//SAM domain (Sterile alpha motif)//Sterile alpha motif    (SAM)/Pointed domain-   BRCOC20000470//TPR Domain//TPR Domain-   BRSSN20005610//PDZ domain (Also known as DHR or GLGF).-   BRSSN20005660//Bacterial type II secretion system protein-   BRSSN20066440//SCAN domain//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type-   BRSSN20074640//Peptidase family M48-   BRSSN20093890//Kelch motif//Kelch motif-   CD34C20001750//Immunoglobulin domain//Immunoglobulin domain-   CTONG20004110//Ank repeat//Ank repeat//Ank repeat//Ank repeat//Ank    repeat//Tropomyosins//Transient receptor//Apolipoprotein A1/A4/E    family//MutS family, N-terminal putative DNA binding domain//K-box    region//Outer membrane efflux protein-   CTONG20004520//SH3 domain-   CTONG20007660//Caspase recruitment domain//DNA polymerase (viral)    N-terminal domain//bZIP transcription factor//K-box region-   CTONG20008190//ADP-ribosylation factor family//Ras family-   CTONG20017490//Sema domain//Sema domain//Integrins, beta    chain//Plexin repeat-   CTONG20020950//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type-   CTONG20029030//Leucine Rich Repeat//Leucine Rich Repeat//Leucine    Rich Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat//Leucine Rich Repeat//Leucine Rich Repeat-   CTONG20030280//WD domain, G-beta repeat//Gram-negative pili assembly    chaperone//WD domain, G-beta repeat//WD domain, G-beta repeat//WD    domain, G-beta repeat//WD domain, G-beta repeat//WD domain, G-beta    repeat-   CTONG20032930//Armadillo/beta-catenin-like repeats-   CTONG20033610//RyR domain-   CTONG20033750//FtsK/SpoIIIE family//ATPases associated with various    cellular activities (AAA)-   CTONG20036990//Immunoglobulin domain//Immunoglobulin domain-   CTONG20044230//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   CTONG20044870//PH domain//PH domain-   CTONG20045500//Translation initiation factor IF-3//HCO3-transporter    family//HCO3-transporter family//Domain of unknown function DUF139-   CTONG20046690//Src homology domain 2-   CTONG20049480//bZIP transcription factor//Carbamoyl-phosphate    synthase (CPSase)//tRNA synthetases class I (C)-   CTONG20060040//NusB family-   CTONG20063770//KE2 family protein//Spectrin repeat-   CTONG20063930//SH3 domain//WW domain//WW domain//PH domain//RhoGAP    domain-   CTONG20066110//TPR Domain//TPR Domain-   CTONG20068360//Mitochondrial carrier proteins//Mitochondrial carrier    proteins-   CTONG20069420//Ribosomal protein S14p/S29e-   CTONG20070090//Bacterial luciferase-   CTONG20070720//PH domain//RhoGAP domain//bZIP transcription factor-   CTONG20070910//PCI domain-   CTONG20071040//Beta/Gamma crystallin//Beta/Gamma    crystallin//Beta/Gamma crystallin//Beta/Gamma crystallin//Similarity    to lectin domain of ricin beta-chain, 3 copies.-   CTONG20071680//3′-5′ exonuclease//Cytochrome c oxidase subunit    III//Ammonium Transporter Family//7 transmembrane receptor (Secretin    family)-   CTONG20072930//KRAB box//Ribosomal protein L20//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Transcription factor S-II    (TFIIS)//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Putative zinc finger in    N-recognin//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   CTONG20074000//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   CTONG20074170//DENN (AEX-3) domain-   CTONG20076810//Ribosomal protein L16//Pheromone A receptor-   CTONG20079590//Sialyltransferase family-   CTONG20083430//Nuclear transition protein 2-   CTONG20083980//WH1 domain-   CTONG20084660//SCAN domain-   CTONG20085210//Lipase (class 3)-   CTONG20165750//G-patch domain//Double-stranded RNA binding motif-   CTONG20169040//bZIP transcription factor//Adenylate    cyclase//Intermediate filament proteins-   CTONG20170940//Ank repeat//Ank repeat//Ank repeat//SAM domain    (Sterile alpha motif)-   CTONG20174580//TBC domain-   CTONG20176040//ADP-ribosylation factor family//Ras family-   CTONG20180690//Collagen triple helix repeat (20 copies)-   CTONG20183430//Ank repeat//Ank repeat//Ank repeat//Ank repeat//Ank    repeat//Ank repeat//Ank repeat//Ank repeat//Zinc finger, C3HC4 type    (RING finger)//Zinc finger, C3HC4 type (RING finger)//Zinc finger,    C3HC4 type (RING finger)-   CTONG20184830//ABC transporter-   CTONG20186290//Aldehyde dehydrogenase family-   CTONG20186370//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   CTONG20186520//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Transcription    factor S-II (TFIIS)//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type-   CTONG20186550//BTB/POZ domain//K+ channel tetramerisation domain-   CTONG20188080//TPR Domain-   CTONG20189000//RhoGEF domain-   CTONG20190290//R3H domain//RNA dependent RNA    polymerase//Uncharacterized protein family UPF0024-   DFNES20025500//Sigma-54 interaction domain//ATPases associated with    various cellular activities (AAA)-   DFNES20043710//Src homology domain 2//Domain of unknown function    DUF36-   DFNES20055400//Viral coat protein//Putative diphthamide synthesis    protein//Influenza non-structural protein (NS1)-   DFNES20057660//Plant thionins//Mitochondrial carrier    proteins//Mitochondrial carrier proteins-   DFNES20072990//Integral membrane protein DUF6//Integral membrane    protein DUF6-   DFNES20073320//Zinc finger, C3HC4 type (RING    finger)//PHD-finger//B-box zinc finger.-   DFNES20076340//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type-   DFNES20080880//Glycosyl transferases//Similarity to lectin domain of    ricin beta-chain, 3 copies.-   DFNES20094820//PHD-finger//Zn-finger in ubiquitin-hydrolases and    other proteins-   FCBBF10000230//Sec7 domain//PH domain-   FCBBF10004760//HMG (high mobility group) box-   FCBBF20018680//C2 domain//C2 domain-   FCBBF20020440//Urease-   FCBBF20023490//Helicases conserved C-terminal domain-   FCBBF20033360//BTB/POZ domain//Kelch motif//Kelch motif//Kelch    motif//Kelch motif//Kelch motif-   FCBBF20035430//AN1-like Zinc finger//AN1-like Zinc finger-   FCBBF20035490//KH domain-   FCBBF20041380//SAM domain (Sterile alpha motif)-   FCBBF20043730//UBA domain-   FCBBF20059660//TPR Domain-   FCBBF20066340//PH domain-   FCBBF20070950//DNA binding domain with preference for A/T rich    regions-   FCBBF30001100//DENN (AEX-3) domain//PPR repeat-   FCBBF30002270//linker histone H1 and H5 family-   FCBBF30003610//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Plant PEC family metallothionein//DM DNA binding    domain//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//PHD-finger//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Phorbol esters/diacylglycerol binding    domain (C1 domain)-   FCBBF30004340//Ribosomal protein S3, C-terminal domain.//Similarity    to lectin domain of ricin beta-chain, 3 copies.-   FCBBF30005360//Sigma-54 interaction domain//ATPases associated with    various cellular activities (AAA)//ATPases associated with various    cellular activities (AAA)-   FCBBF30005500//PH domain//PH domain//Putative GTP-ase activating    protein for Arf-   FCBBF30019140//‘chromo’ (CHRromatin Organization MOdifier)    domain//‘chromo’ (CHRromatin Organization MOdifier)    domain//DEAD/DEAH box helicase//SNF2 and others N-terminal    domain//Helicases conserved C-terminal domain-   FCBBF30019180//Armadillo/beta-catenin-like repeats//Lipoprotein    amino terminal region-   FCBBF30021900//Zinc finger, C2H2 type//Zinc finger, C2H2    type//PHD-finger//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//BolA-like    protein//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Snake    toxin//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   FCBBF30022680//3′-5′ exonuclease-   FCBBF30029250//SET domain-   FCBBF30035570//C2 domain-   FCBBF30048420//T-box//wnt family of developmental signaling proteins-   FCBBF30071500//Influenza RNA-dependent RNA polymerase subunit    PB1//Reprolysin family propeptide//Leptin-   FCBBF30076310//Eukaryotic protein kinase domain//Eukaryotic protein    kinase domain//Protein kinase C terminal domain-   FCBBF30079770//D-isomer specific 2-hydroxyacid dehydrogenases-   FCBBF30080730//RNA recognition motif. (a.k.a. RRM, RBD, or RNP    domain)//Zinc knuckle-   FCBBF30085560//Pyridine nucleotide-disulphide oxidoreductase//FAD    binding domain//Flavin containing amine oxidase//Phytoene    dehydrogenase related enzyme-   FCBBF30093170//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   FCBBF30100080//Sec7 domain-   FCBBF30100120//PDZ domain (Also known as DHR or GLGF).-   FCBBF30100410//Nucleosome assembly protein (NAP)-   FCBBF30118670//Reprolysin (M12B) family zinc    metalloprotease//Disintegrin//EB module//Hantavirus glycoprotein    G2//Adenovirus E3 region protein CR2//jmjN domain-   FCBBF30125460//Zinc finger, C3HC4 type (RING finger)-   FCBBF30129010//KRAB box//Zinc finger, C2H2 type//GATA zinc    finger//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Transcription factor S-II    (TFIIS)//Zinc finger, C2H2 type-   FCBBF30130410//UvrB/uvrC motif-   FCBBF30132050//Galactosyltransferase//Fringe-like-   FCBBF30132660//Leucine rich repeat N-terminal domain//Leucine Rich    Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat-   FCBBF30136230//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Cystatin domain//Homeobox    domain//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type-   FCBBF30142290//PHD-finger-   FCBBF30143550//Phosphatidylinositol-4-phosphate 5-Kinase-   FCBBF30153170//Phosphofructokinase//Phosphofructokinase//Phosphofructokinase//Phosphofructokinase-   FCBBF30161780//gag gene protein p24 (core nucleocapsid    protein)//Zinc knuckle FCBBF30164510//Cadherin domain//Cadherin    domain//Cadherin domain//Fructose-bisphosphate aldolase    class-I//Cadherin domain//Cadherin domain//Alphaherpesvirus    glycoprotein E//Cadherin cytoplasmic region-   FCBBF30166220//Serine hydroxymethyltransferase-   FCBBF30169280//PHD-finger//Zinc finger, C3HC4 type (RING finger)-   FCBBF30171230//Subtilase family//Proprotein convertase P-domain-   FCBBF30173960//Beta-lactamase//TPR Domain-   FCBBF30194550//Arsenical pump membrane protein//Ank repeat//Ank    repeat//Ank repeat//Ank repeat//Ank repeat//Dehydrogenase E1    component//Ank repeat//Ank repeat//Ank repeat//Ank repeat//Ank    repeat//Ank repeat//Ank repeat-   FCBBF30195690//C2 domain-   FCBBF30197840//Sushi domain (SCR repeat)//CUB domain//Sushi domain    (SCR repeat)//CUB domain//Sushi domain (SCR repeat)//Sushi domain    (SCR repeat)//Sushi domain (SCR repeat)-   FCBBF30212210//Immunoglobulin domain-   FCBBF30215240//PH domain//FERM domain (Band 4.1 family)-   FCBBF30220050//Ligand-binding domain of nuclear hormone receptor-   FCBBF30222910//Corticotropin-releasing factor family-   FCBBF30236670//DEAD/DEAH box helicase-   FCBBF30250980//WD domain, G-beta repeat//WD domain, G-beta    repeat//WD domain, G-beta repeat//WD domain, G-beta repeat//WD    domain, G-beta repeat//WD domain, G-beta repeat-   FCBBF30255680//Vesicular monoamine transporter//GGL    domain//Ezrin/radixin/moesin family//Ank repeat//Ank repeat-   FCBBF30257370//Geminivirus AL1 protein//Outer membrane efflux    protein-   FCBBF30259050//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger present in dystrophin, CBP/p300//Zinc    finger, C2H2 type//PHD-finger//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//DM DNA binding domain//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Transcription factor S-II (TFIIS)//Zinc finger, C2H2    type//TRAF-type zinc finger//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type-   FCBBF30260210//SNF2 and others N-terminal domain//Helicases    conserved C-terminal domain//Domain of unknown function DUF94-   FCBBF30263080//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   FCBBF30266510//Domain of unknown function DUF71-   FCBBF30271990//Ank repeat//Ank repeat//Ank repeat//Ank repeat//Ank    repeat//Ank repeat//Ank repeat//Ank repeat//Ank repeat//Ank    repeat//Ank repeat//Ank repeat-   FCBBF30275590//LIM domain containing proteins-   FCBBF30282020//Ank repeat//Ank repeat//Ank repeat//K+ channel    tetramerisation domain//BTB/POZ domain-   FCBBF30285930//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   FCBBF50001650//MORN motif//MORN motif//MORN motif//MORN motif//MORN    motif//MORN motif//MORN motif//MORN motif-   FCBBF50003530//Zinc finger, C3HC4 type (RING finger)-   FCBBF50004950//Putative replicase 1 (ORF2)-   FEBRA20005040//Intermediate filament proteins//Hr1 repeat    motif//Troponin//GrpE-   FEBRA20007820//DNA polymerase family B-   FEBRA20018670//Viral methyltransferase//Ribosomal protein    S19//Alpha-2-macroglobulin family N-terminal region-   FEBRA20026820//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Putative zinc finger in N-recognin//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   FEBRA20027070//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Transcription factor S-II (TFIIS)//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//TRAF-type zinc    finger//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type-   FEBRA20029620//Leucine Rich Repeat//Leucine Rich Repeat//Leucine    Rich Repeat-   FEBRA20031000//Leucine Rich Repeat//Leucine Rich Repeat//Leucine    Rich Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat//Insulin/IGF/Relaxin family//Ribosomal RNA adenine    dimethylases//SAM domain (Sterile alpha motif)//TFIIE alpha    subunit//Zinc finger, C3HC4 type (RING finger)-   FEBRA20031280//Protein of unknown function DUF82-   FEBRA20038330//Corticotropin-releasing factor family-   FEBRA20038970//Laminin EGF-like (Domains III and V)//Phorbol    esters/diacylglycerol binding domain (C1 domain)//EGF-like    domain//EGF-like domain//Trypsin Inhibitor like cysteine rich    domain//Metallothionein//EGF-like domain//EGF-like    domain//Extracellular link domain-   FEBRA20046200//Ank repeat//Ank repeat//Ank repeat//Ank repeat//Ank    repeat//Ank repeat//Ank repeat-   FEBRA20046510//Zinc finger, C2H2 type//Zinc finger, C2H2    type//BolA-like protein//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   FEBRA20063720//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type-   FEBRA20078800//NADH ubiquinone oxidoreductase, 20 Kd subunit-   FEBRA20080860//Hantavirus glycoprotein G2-   FEBRA20087550//WD domain, G-beta repeat//WD domain, G-beta repeat-   FEBRA20088610//CRAL/TR10 domain.-   FEBRA20088810//Fibroblast growth factor-   FEBRA20090160//Nuclear transition protein 2-   FEBRA20090220//Nucleotidyl transferase//Bacterial transferase    hexapeptide (four repeats)//Bacterial transferase hexapeptide (four    repeats)//Bacterial transferase hexapeptide (four repeats)//Domain    of unknown function DUF29//Peptide    hormone//eIF4-gamma/eIF5/eIF2-epsilon-   FEBRA20092760//LIM domain containing proteins//LIM domain containing    proteins//LIM domain containing proteins-   FEBRA20115930//Divalent cation transporter//Translation initiation    factor IF-3//Divalent cation transporter-   FEBRA20150420//Transient receptor//Borrelia ORF-A//Transient    receptor FEBRA20170240//SCAN domain//KRAB box//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type-   FEBRA20172230//Phospholipase D. Active site motif//Phospholipase D.    Active site motif-   FEBRA20173330//Eukaryotic protein kinase domain-   FEBRA20175330//D-isomer specific 2-hydroxyacid dehydrogenases-   FEBRA20191720//GGL domain//Regulator of G protein signaling domain-   HCHON10000150//LIM domain containing proteins//LIM domain containing    proteins//LIM domain containing proteins//Zinc finger, C3HC4 type    (RING finger)-   HCHON20000870//Eukaryotic protein kinase domain-   HCHON20002650//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type-   HCHON20002710//Ubiquitin carboxyl-terminal hydrolase family 2-   HCHON20015050//von Willebrand factor type A domain//IPT/TIG    domain//Sm protein-   HEART10001420//MYND finger//SET domain-   HEART10001490//FAD binding domain-   HEART20009590//Peptidase family M41-   HEART20019310//Zinc finger, C3HC4 type (RING    finger)//PHD-finger//B-box zinc finger.-   HEART20022200//Influenza Matrix protein (M1)//metallopeptidase    family M24-   HEART20047640//3′ 5′-cyclic nucleotide phosphodiesterase//Formin    Homology 2 Domain-   HEART20082570//C-5 cytosine-specific DNA methylase//Glycine cleavage    T-protein (aminomethyl transferase)-   HHDPC20081230//RNA recognition motif. (a.k.a. RRM, RBD, or RNP    domain)//RNA recognition motif. (a.k.a. RRM, RBD, or RNP    domain)//RNA recognition motif. (a.k.a. RRM, RBD, or RNP    domain)//RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)-   HHDPC20088160//PDZ domain (Also known as DHR or GLGF).-   HLUNG20008460//bZIP transcription factor-   HLUNG20011260//Eukaryotic protein kinase domain-   HLUNG20011460//RNA recognition motif. (a.k.a. RRM, RBD, or RNP    domain)//RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)-   HLUNG20014590//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Putative zinc finger in N-recognin//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Transcription factor S-II (TFIIS)//Zinc finger,    C2H2 type//Zinc finger, C2H2 type-   HLUNG20015070//Leucine rich repeat N-terminal domain//Leucine Rich    Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat//Leucine rich repeat C-terminal domain//Immunoglobulin domain-   HLUNG20024050//Rubredoxin-   HLUNG20028110//Zinc finger, C3HC4 type (RING finger)//TPR    Domain//TPR Domain//TPR Domain//Zinc finger, C3HC4 type (RING    finger)//Aldo/keto reductase family-   HLUNG20030420//Ank repeat//Ank repeat//Ank repeat//Ank repeat//Ank    repeat-   HLUNG20032460//Prolyl oligopeptidase family//Lipoate-protein ligase    B//alpha/beta hydrolase fold-   HLUNG20033060//HMG (high mobility group) box-   HLUNG20041590//TPR Domain//TPR Domain//Domain of unknown function    DUF27-   HLUNG20042730//Cytochrome P450-   HLUNG20051330//FHIPEP family-   HLUNG20063700//Progesterone receptor-   HLUNG20065990//bZIP transcription factor//SNAP-25 family//Syntaxin-   HLUNG20068120//Fimbrial Usher proteins-   HLUNG20069350//EF hand//EF hand//EF hand-   HLUNG20070410//Dihydropyridine sensitive L-type calcium channel    (Beta subunit)-   HLUNG20081390//DnaJ domain-   HLUNG20082350//PH domain//START domain-   HLUNG20083330//DNA polymerase III beta subunit//Fibrillar collagen    C-terminal domain-   HLUNG20084790//WD domain, G-beta repeat//WD domain, G-beta    repeat//WD domain, G-beta repeat-   HLUNG20085210//C2 domain-   KIDNE20016360//PAS domain//PAC motif//Ion transport    protein//Transmembrane region cyclic Nucleotide Gated    Channel//Cyclic nucleotide-binding domain-   KIDNE20027980//SAM domain (Sterile alpha motif)-   KIDNE20080690//Glycosyl hydrolases family 18//Aminotransferases    class-III pyridoxal-phosphate//Methyl-accepting chemotaxis protein    (MCP) signaling domain//Aminotransferases class-III    pyridoxal-phosphate-   KIDNE20081170//Kinesin motor domain//Kinesin motor domain-   KIDNE20083620//Asparaginase-   KIDNE20084030//Sugar (and other) transporter-   KIDNE20084730//Neuraxin and MAP1B proteins//Formin Homology 2 Domain-   KIDNE20086490//gag gene protein p24 (core nucleocapsid protein)-   KIDNE20087880//Reverse transcriptase (RNA-dependent DNA polymerase)-   KIDNE20088240//EF hand//EF hand//EF hand-   KIDNE20089870//WD domain, G-beta repeat//WD domain, G-beta    repeat//WD domain, G-beta repeat//WD domain, G-beta repeat//WD    domain, G-beta repeat//WD domain, G-beta repeat-   KIDNE20094670//Sigma-54 interaction domain//FtsK/SpoIIIE    family//ATPases associated with various cellular activities (AAA)-   KIDNE20133880//G-protein alpha subunit-   KIDNE20141700//Ribosomal family S4e-   KIDNE20142900//EGF-like domain//EB module//EGF-like domain//EGF-like    domain-   KIDNE20148080//Zinc finger, C3HC4 type (RING finger)-   KIDNE20149780//Ank repeat//Ank repeat//Ank repeat-   KIDNE20152440//Trypsin//PDZ domain (Also known as DHR or GLGF).-   KIDNE20154330//PDZ domain (Also known as DHR or GLGF).//PDZ domain    (Also known as DHR or GLGF).//PDZ domain (Also known as DHR or    GLGF).//PDZ domain (Also known as DHR or GLGF).//PDZ domain (Also    known as DHR or GLGF).//PDZ domain (Also known as DHR or GLGF).-   KIDNE20160360//Sec7 domain//PH domain-   KIDNE20169180//EGF-like domain//EB module//EGF-like domain//Trypsin    Inhibitor like cysteine rich domain//EGF-like domain//TNFR/NGFR    cysteine-rich region//Zona pellucida-like domain-   KIDNE20170400//Leucine Rich Repeat//Leucine Rich Repeat//Leucine    Rich Repeat//Protein kinase C terminal domain//Rubredoxin-   KIDNE20173150//Acetyltransferase (GNAT) family-   KIDNE20173430//PDZ domain (Also known as DHR or GLGF).//PDZ domain    (Also known as DHR or GLGF).-   KIDNE20186170//UDP-glucoronosyl and UDP-glucosyl transferases-   KIDNE20189960//Trehalase-   LIVER20006260//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Plant PEC family    metallothionein//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   LIVER20007750//Sugar (and other) transporter-   LIVER20010760//Lectin C-type domain-   LIVER20010990//DNA gyrase/topoisomerase IV, subunit A-   LIVER20013890//tRNA synthetases class I (C)-   LIVER20026440//Cytochrome P450-   LIVER20030650//General diffusion Gram-negative porins-   LIVER20038000//Mitochondrial carrier proteins//Mitochondrial carrier    proteins//Mitochondrial carrier proteins-   LIVER20040740//CRAL/TR10 domain.-   LIVER20055270//AIR synthase related protein-   MESAN20006200//Annexin//Annexin-   MESAN20008150//IBR domain-   MESAN20009090//CUB domain-   MESAN20016270//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type-   MESAN20021130//SH3 domain//Eukaryotic protein kinase domain-   MESAN20021220//Leucine Rich Repeat//Leucine Rich Repeat//Leucine    Rich Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat//Leucine rich repeat C-terminal domain//Leucine rich repeat    N-terminal domain//Leucine Rich Repeat//Leucine Rich Repeat//Leucine    Rich Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine rich    repeat C-terminal domain-   MESAN20026870//PAN domain//TBC domain-   MESAN20027240//RhoGEF domain-   MESAN20027900//von Willebrand factor type A domain//von Willebrand    factor type A domain//von Willebrand factor type A    domain//Protozoan/cyanobacterial globin//von Willebrand factor type    A domain//von Willebrand factor type A domain-   MESAN20030350//LGN motif, putative GEF specific for G-alpha    GTPase//DNA gyrase/topoisomerase IV, subunit A-   MESAN20030370//Porphobilinogen deaminase//GHMP kinases putative    ATP-binding proteins//Protein of unknown function DUF113-   MESAN20034440//Viral DNA-binding protein//Uncharacterized protein    family UPF0024-   MESAN20038520//Caspase recruitment domain//RNA polymerase beta    subunit-   MESAN20057240//Elongation factor TS//Helix-hairpin-helix motif.-   MESAN20058110//FKBP-type peptidyl-prolyl cis-trans    isomerases//Elongation factor Tu family//FKBP-type peptidyl-prolyl    cis-trans isomerases//FKBP-type peptidyl-prolyl cis-trans isomerases-   MESAN20059570//EGF-like domain//SEA domain//Immunoglobulin domain-   MESAN20060430//SET domain-   MESAN20067430//Tropomyosins-   MESAN20069530//Calponin homology (CH) domain//PDZ domain (Also known    as DHR or GLGF).-   MESAN20090190//EGF-like domain//EGF-like domain//EGF-like    domain//EGF-like domain//EGF-like domain//EGF-like    domain//Metallothionein//CUB domain-   MESAN20095220//Adaptin N terminal region-   MESAN20095800//Cyclophilin type peptidyl-prolyl cis-trans    isomerase//RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)-   NT2NE20018890//WD domain, G-beta repeat//WD domain, G-beta    repeat//WD domain, G-beta repeat//WD domain, G-beta repeat-   NT2NE20026200//Transketolase-   NT2NE20026510//Zinc finger, C3HC4 type (RING finger)-   NT2NE20038870//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Lipoprotein-   NT2NE20042550//Viral (Superfamily 1) RNA helicase//NB-ARC    domain//Adenylate kinase//Adenylate kinase-   NT2NE20053950//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   NT2NE20060750//KRAB box//Zinc finger, C2H2 type-   NT2NE20061030//SCAN domain-   NT2NE20077270//Adenovirus EB1 55K protein/large t-antigen-   NT2NE20079670//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Transcription    factor S-II (TFIIS)//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type-   NT2NE20087270//Tudor domain-   NT2NE20092950//Fibronectin type III domain-   NT2NE20108420//Domain of unknown function DUF130//Oxysterol-binding    protein-   NT2NE20117580//NADH ubiquinone oxidoreductase, 20 Kd subunit-   NT2NE20127900//Myo-inositol-1-phosphate synthase-   NT2NE20140130//Sema domain-   NT2NE20145250//Stathmin family-   NT2NE20153620//FERM domain (Band 4.1 family)//PH domain-   NT2RI20093010//Tetrahydrofolate dehydrogenase/cyclohydrolase-   NT2RP70001120//Ank repeat//Ank repeat//Ank repeat//Insulinase    (Peptidase family M16)-   NT2RP70001730//BTB/POZ domain//Kelch motif//Kelch motif//Kelch    motif//Kelch motif//Kelch motif-   NT2RP70003110//Collagen triple helix repeat (20    copies)//Heavy-metal-associated domain-   NT2RP70027790//Leucine Rich Repeat//Leucine Rich Repeat//Leucine    Rich Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat//Leucine Rich Repeat-   NT2RP70029780//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//PHD-finger//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Transcription factor S-II (TFIIS)-   NT2RP70030840//Viral (Superfamily 1) RNA helicase-   NT2RP70031070//Nucleoside transporter-   NT2RP70031340//PHD-finger-   NT2RP70046410//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type-   NT2RP70056690//Thrombospondin type 1 domain//Domain of unknown    function DUF18//Thrombospondin type 1 domain//Thrombospondin type 1    domain//Thrombospondin type 1 domain//Thrombospondin type 1    domain//Keratin, high sulfur B2 protein-   NT2RP70057500//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//DnaJ central domain (4 repeats)//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type-   NT2RP70064570//Calpain family cysteine protease//Calpain large    subunit, domain III//EF hand//EF hand-   NT2RP70075300//KRAB box//Domain of unknown function DUF19//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type-   NT2RP70075800//recA bacterial DNA recombination proteins//WD domain,    G-beta repeat//WD domain, G-beta repeat//WD domain, G-beta    repeat//WD domain, G-beta repeat//WD domain, G-beta repeat//WD    domain, G-beta repeat//SH3 domain-   NT2RP70090870//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//DM DNA binding    domain//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Transcription factor S-II (TFIIS)//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type-   NTONG20005310//Ribosomal protein S9/S16-   NTONG20029850//EF hand//EF hand//EF hand-   NTONG20031580//Hsp20/alpha crystallin family-   NTONG20032100//Intermediate filament proteins-   NTONG20034540//GAF domain//GAF domain//3′ 5′-cyclic nucleotide    phosphodiesterase-   NTONG20035150//BTB/POZ domain//Kelch motif//Kelch motif//Kelch    motif//Kelch motif//Kelch motif-   NTONG20043080//Immunoglobulin domain//Immunoglobulin    domain//Immunoglobulin domain-   NTONG20048440//PH domain//K-box region-   NTONG20053630//DNA binding domain with preference for A/T rich    regions//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Progesterone    receptor//Zinc finger, C2H2 type-   NTONG20053730//Ribosomal protein S2//Ubiquitin carboxyl-terminal    hydrolases family 2//Ubiquitin carboxyl-terminal hydrolase family 2-   NTONG20053910//Translin family//PH domain//Putative GTP-ase    activating protein for Arf//Ank repeat//Ank repeat-   NTONG20055200//Calcium channel extracellular region//Elongation    factor Tu family//Elongation factor G C-terminus-   NTONG20058010//AMP-binding enzyme-   OCBBF20000740//Leucine rich repeat N-terminal domain//Leucine Rich    Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat//Leucine Rich Repeat//Leucine rich repeat C-terminal    domain//Immunoglobulin domain-   OCBBF20011860//LIM domain containing proteins-   OCBBF20012520//Leucine rich repeat N-terminal domain//Leucine Rich    Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat//Leucine Rich Repeat//Leucine rich repeat C-terminal    domain//Immunoglobulin domain-   OCBBF20016390//Chitin synthase//Fibronectin type II domain-   OCBBF20016810//‘Paired box’ domain-   OCBBF20110210//Immunoglobulin domain//Immunoglobulin    domain//Immunoglobulin domain-   OCBBF20113110//AP endonuclease family 1-   OCBBF20116250//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//PHD-finger//Zinc finger, C2H2 type-   OCBBF20120010//Thrombospondin type 1 domain-   OCBBF20120950//K+ channel tetramerisation domain//BTB/POZ    domain//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   OCBBF20121910//Ribosomal protein L24e-   OCBBF20147070//DNA polymerase (viral) C-terminal domain-   OCBBF20156450//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type-   OCBBF20157970//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//TRAF-type zinc finger//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//DM DNA binding domain//Zinc    finger, C2H2 type-   OCBBF20165910//DnaB-like helicase-   OCBBF20166890//CAP-Gly domain//CAP-Gly domain-   OCBBF20166900//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Transcription factor S-II (TFIIS)//Zinc finger,    C2H2 type//Zinc finger, C2H2 type-   OCBBF20167290//haloacid dehalogenase-like    hydrolase//Thioredoxin//Aminoglycoside phosphotransferase//Acyl-CoA    dehydrogenase-   OCBBF20174580//Cyclin-   OCBBF20174890//Death domain-   OCBBF20175360//Zinc finger, C2H2 type-   OCBBF20177540//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Src homology domain 2//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   OCBBF20177910//Corticotropin-releasing factor family-   OCBBF20182060//Inward rectifier potassium channel-   OCBBF20191950//EGF-like domain//Low-density lipoprotein receptor    domain class A//Low-density lipoprotein receptor domain class    A//EGF-like domain//Low-density lipoprotein receptor domain class    A//EGF-like domain//Low-density lipoprotein receptor domain class    A//Low-density lipoprotein receptor domain class A//EGF-like    domain//EGF-like domain//Low-density lipoprotein receptor repeat    class B//Low-density lipoprotein receptor repeat class    B//Low-density lipoprotein receptor repeat class B//Low-density    lipoprotein receptor repeat class B//Low-density lipoprotein    receptor repeat class B//EGF-like domain//60 Kd inner membrane    protein-   PANCR10000860//Trypsin//Trypsin-   PEBLM10001470//Zinc finger, C2H2 type//Fork head domain-   PEBLM20001800//Immunoglobulin domain//Immunoglobulin    domain//Immunoglobulin domain//Immunoglobulin domain//Immunoglobulin    domain-   PEBLM20003260//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Transcription factor S-II (TFIIS)//Src homology domain 2//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Src homology domain    2//Zinc finger, C2H2 type-   PEBLM20005020//Virion host shutoff protein-   PLACE50001390//PHD-finger-   PLACE60004260//Cystatin domain-   PLACE60006300//Immunoglobulin domain-   PLACE60012620//WD domain, G-beta repeat//WD domain, G-beta    repeat//WD domain, G-beta repeat//WD domain, G-beta repeat//AN1-like    Zinc finger//FYVE zinc finger-   PLACE60054230//CheR methyltransferase//Formin Homology 2 Domain-   PLACE60054820//Regulator of chromosome condensation    (RCC1)//Regulator of chromosome condensation (RCC1)//Regulator of    chromosome condensation (RCC1)//Regulator of chromosome condensation    (RCC1)-   PLACE60054870//IQ calmodulin-binding motif//IQ calmodulin-binding    motif-   PLACE60055590//Zinc finger, C3HC4 type (RING finger)-   PLACE60061370//Phosphotyrosine interaction domain    (PTB/PID).//Extracellular link domain-   PLACE60062660//Gamma-adaptin, C-terminus-   PLACE60064180//Lumenal portion of Cytochrome b559, alpha (gene psbE)    subunit.//Viral (Superfamily 1) RNA helicase-   PLACE60066970//SCAN domain//Zinc finger, C2H2 type//PHD-finger//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   PLACE60070500//Immunoglobulin domain//Immunoglobulin domain-   PLACE60073090//Myo-inositol-1-phosphate synthase-   PLACE60074820//Adenylate kinase-   PLACE60082850//Pathogenesis-related protein Bet v I family-   PLACE60087680//Thyroglobulin type-1 repeat-   PLACE60093380//Penicillin amidase//Bacterial regulatory proteins,    lacI family//Vacuolar sorting protein 9 (VPS9) domain-   PLACE60095600//DEAD/DEAH box helicase-   PLACE60098350//MAGE family-   PLACE60104630//Photosystem I reaction centre subunit VIII-   PLACE60113340//EGF-like domain//Laminin G domain//Insulin-like    growth factor binding proteins//EGF-like domain//Laminin G domain-   PLACE60118810//bZIP transcription factor//TPR Domain//TPR    Domain//TPR Domain//TPR Domain//PPR repeat-   PLACE60119700//EF hand-   PLACE60122970//Zinc finger, C2H2 type-   PLACE60138840//Syndecan domain//Mitochondrial carrier    proteins//Mitochondrial carrier proteins//Mitochondrial carrier    proteins-   PLACE60140640//Phosphoribulokinase//Shikimate    kinase//Uncharacterized protein family UPF0038-   PLACE60154450//RhoGAP domain-   PLACE60177880//Immunoglobulin domain//Immunoglobulin domain-   PLACE60181870//Pentaxin family-   PLACE60184870//LBP/BPI/CETP family-   PROST10001100//Keratin, high sulfur B2 protein-   PROST20007170//KRAB box//Zinc finger, C2H2    type//Cyclopropane-fatty-acyl-phospholipid synthase//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Transcription factor S-II    (TFIIS)//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type-   PROST20015210//Myosin tail//Borrelia lipoproteins//Myosin tail-   PROST20016760//‘chromo’ (CHRromatin Organization MOdifier) domain-   PROST20024250//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type-   PROST20028970//Ank repeat//Ank repeat//Glutamine amidotransferases    class-II//Ank repeat//Ank repeat-   PROST20033240//Ephrin receptor ligand binding domain//EB    module//TNFR/NGFR cysteine-rich region//Fibronectin type III domain-   PROST20036350//Glutathione S-transferases.//Ribosomal protein    S24e//Interferon alpha/beta domain//tRNA synthetases class I (E and    Q)-   PROST20045700//Keratin, high sulfur B2 protein-   PROST20050390//Cytochrome P450-   PROST20051310//DEAD/DEAH box helicase//Toprim domain//Helicases    conserved C-terminal domain//Zinc knuckle-   PROST20065790//Phosphofructokinase//Phosphofructokinase//Phosphofructokinase//Phosphofructokinase-   PROST20073280//Transposase-   PROST20075280//Immunoglobulin domain//Immunoglobulin    domain//Thrombospondin type 1 domain-   PROST20082430//Cyclophilin type peptidyl-prolyl cis-trans isomerase-   PROST20084720//Cytochrome P450-   PROST20087240//gag gene protein p24 (core nucleocapsid protein)-   PROST20099090//Disintegrin-   PROST20102190//EF hand//Ribosomal RNA adenine dimethylases//EF hand-   PROST20105450//Sodium/hydrogen exchanger family-   PROST20127450//TSC-22/dip/bun family-   PROST20130320//S-100/ICaBP type calcium binding domain-   PROST20152510//TPR Domain//TPR Domain//TPR Domain-   PROST20155370//SCAN domain//KRAB box//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type-   PROST20168600//KTN NAD-binding domain-   PUAEN10000650//TSC-22/dip/bun family-   PUAEN10001640//Leucine Rich Repeat//Leucine Rich Repeat//Leucine    Rich Repeat//Leucine Rich Repeat-   PUAEN20000800//Bleomycin resistance protein-   PUAEN20001520//Acetyltransferase (GNAT) family-   PUAEN20002470//FtsK/SpoIIIE family-   PUAEN20003120//Myb-like DNA-binding domain//ATP synthase ab C    terminal//SET domain-   SALGL10001070//Family 4 glycosyl hydrolase-   SKMUS20006790//von Willebrand factor type D domain-   SKMUS20007260//Syndecan domain-   SKMUS20008730//Calponin homology (CH) domain-   SKMUS20017400//Hantavirus nucleocapsid protein//Tropomyosins-   SKMUS20040440//Ribosomal protein L3-   SKMUS20091900//Trypsin-   SKNMC10001230//Ank repeat//Ank repeat//Ank repeat-   SKNMC20006350//FKBP-type peptidyl-prolyl cis-trans    isomerases//FKBP-type peptidyl-prolyl cis-trans    isomerases//FKBP-type peptidyl-prolyl cis-trans isomerases//EF    hand//EF hand-   SKNSH20009710//Tropomyosins//Tropomyosins-   SKNSH20052400//WD domain, G-beta repeat//WD domain, G-beta    repeat//WD domain, G-beta repeat//WD domain, G-beta repeat//WD    domain, G-beta repeat//WD domain, G-beta repeat-   SKNSH20057920//Eukaryotic protein kinase domain-   SMINT20000070//Rabphilin-3A effector domain-   SMINT20002320//Protein phosphatase 2A regulatory B subunit (B56    family)-   SMINT20006020//PH domain//Phorbol esters/diacylglycerol binding    domain (C1 domain)//FYVE zinc finger//PH domain-   SMINT20006090//Glutathione S-transferases.-   SMINT20008110//Na+/K+ ATPase C-terminus-   SMINT20011950//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//PHD-finger//Zinc finger, C2H2 type-   SMINT20012220//Collagen triple helix repeat (20 copies)-   SMINT20016150//gag gene protein p17 (matrix protein).//Ferritins-   SMINT20024140//Immunoglobulin domain-   SMINT20028800//Zinc finger, C2HC type//SAM domain (Sterile alpha    motif)//Sterile alpha motif (SAM)/Pointed domain-   SMINT20028840//Immunoglobulin domain-   SMINT20030740//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   SMINT20035050//SH3 domain//WW domain//PH domain//RhoGAP domain-   SMINT20036440//ENTH domain-   SMINT20038660//Olfactomedin-like domain-   SMINT20039050//Flavivirus glycoprotein//IBR domain-   SMINT20043390//Ras association (RalGDS/AF-6) domain-   SMINT20044140//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//PHD-finger//Zinc finger, C2H2    type//Zinc finger, C2H2 type-   SMINT20044730//Envelope glycoprotein GP120-   SMINT20048720//Cytochrome P450//Cytochrome P450-   SMINT20052130//Ank repeat//Ank repeat-   SMINT20056230//Immunoglobulin domain//Immunoglobulin    domain//Immunoglobulin domain//Immunoglobulin domain-   SMINT20062050//Reverse transcriptase (RNA-dependent DNA polymerase)-   SMINT20077960//Gelsolin repeat.//Gelsolin repeat.//Gelsolin    repeat.//Gelsolin repeat.-   SMINT20083290//Immunoglobulin domain//Immunoglobulin    domain//Immunoglobulin domain//Immunoglobulin domain//Immunoglobulin    domain-   SMINT20086250//Glycine cleavage H-protein-   SMINT20086720//SCAN domain//KRAB box-   SMINT20088440//Immunoglobulin domain-   SMINT20089600//PDZ domain (Also known as DHR or GLGF).-   SMINT20091190//Immunoglobulin domain//Immunoglobulin    domain//Immunoglobulin domain//Immunoglobulin domain//Immunoglobulin    domain-   SPLEN20006950//Reverse transcriptase (RNA-dependent DNA polymerase)-   SPLEN20011350//Helper component proteinase-   SPLEN20015100//DHHC zinc finger domain-   SPLEN20023540//RasGEF domain//EF hand//EF hand-   SPLEN20023850//RecF protein//SMC domain N terminal    domain//Tropomyosins-   SPLEN20024190//EGF-like domain//EB module//EGF-like domain//Trypsin    Inhibitor like cysteine rich domain//EGF-like domain//EGF-like    domain//WAP-type (Whey Acidic Protein) ‘four-disulfide    core’//EGF-like domain-   SPLEN20024930//Inositol polyphosphate phosphatase family, catalytic    domain-   SPLEN20039180//Fatty acid desaturase-   SPLEN20042200//Zinc finger, C3HC4 type (RING finger)//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type-   SPLEN20049840//Polyphosphate kinase//Myosin head (motor domain)//IQ    calmodulin-binding motif//SH3 domain-   SPLEN20050090//Pyridoxamine 5′-phosphate oxidase//GRIP domain-   SPLEN20054500//Renal dipeptidase-   SPLEN20055600//K+ channel tetramerisation domain//BTB/POZ    domain//Zinc finger, C2H2 type-   SPLEN20057900//Scorpion short toxins//EGF-like domain//EGF-like    domain//Keratin, high sulfur B2 protein-   SPLEN20059270//Zinc finger, C3HC4 type (RING finger)//B-box zinc    finger.//SPRY domain-   SPLEN20063250//Zinc finger, C2H2 type-   SPLEN20063890//Leucine Rich Repeat//Leucine Rich Repeat//Leucine    Rich Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat-   SPLEN20071820//DNA polymerase X family-   SPLEN20076470//TPR Domain//TPR Domain//TPR Domain-   SPLEN20080070//Alpha-L-fucosidase-   SPLEN20085910//Double-stranded RNA binding motif-   SPLEN20090880//Immunoglobulin domain-   SPLEN20098030//Zinc finger, C3HC4 type (RING finger)//B-box zinc    finger.-   SPLEN20101950//Sodium/hydrogen exchanger family-   SPLEN20104150//Ribosomal protein L36-   SPLEN20108000//short chain dehydrogenase-   SPLEN20110180//Transposase-   SPLEN20118050//Leucine rich repeat N-terminal domain//Leucine Rich    Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat//Leucine Rich Repeat-   SPLEN20135030//PDZ domain (Also known as DHR or GLGF).//GATA zinc    finger//LIM domain containing proteins-   SPLEN20139100//Sodium and potassium ATPases//Immunoglobulin    domain//Immunoglobulin domain//Immunoglobulin domain//Immunoglobulin    domain-   SPLEN20139360//Bacterial regulatory proteins, lacI    family//Site-specific recombinases-   SPLEN20175920//Uncharacterized protein family UPF0036-   SPLEN20180980//Glutathione S-transferases.-   SPLEN20182990//BTB/POZ domain//Kelch motif//Kelch motif//Kelch    motif//Kelch motif-   SPLEN20183020//Laminin G domain-   SPLEN20191020//Src homology domain 2-   SPLEN20193790//Dynamin family//Dynamin family//Proteasome activator    pa28 beta subunit//Peroxidase//Dynamin central region//Dynamin    GTPase effector domain-   SPLEN20195710//TPR Domain//TPR Domain//TPR Domain-   SPLEN20197930//K-box region-   SPLEN20198390//WD domain, G-beta repeat//Fibrillarin//WD domain,    G-beta repeat//WD domain, G-beta repeat//WD domain, G-beta    repeat//WD domain, G-beta repeat//WD domain, G-beta repeat//WD    domain, G-beta repeat-   SPLEN20201830//Leucine Rich Repeat//Leucine Rich Repeat//Leucine    Rich Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat//Leucine Rich Repeat//Leucine Rich Repeat//Leucine Rich    Repeat-   TESTI10001570//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//PHD-finger//Zinc finger, C2H2    type//Zinc finger, C2H2 type//TRAF-type zinc finger//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Transcription factor S-II (TFIIS)//Zinc finger,    C2H2 type-   TESTI20006160//Large-conductance mechanosensitive channel,    MscL//CbiM-   TESTI20006830//PWWP domain-   TESTI20012080//Chitin synthase-   TESTI20016970//TPR Domain-   TESTI20030200//Double-stranded RNA binding    motif//Adenosine-deaminase (editase) domain//Adenosine-deaminase    (editase) domain-   TESTI20030440//Plant PEC family metallothionein//Tropomyosins-   TESTI20031310//Serpins (serine protease inhibitors)-   TESTI20038240//Peptidase family M13-   TESTI20041630//Outer membrane efflux protein//Intermediate filament    proteins-   TESTI20043910//IQ calmodulin-binding motif//IQ calmodulin-binding    motif//IQ calmodulin-binding motif//IQ calmodulin-binding motif//IQ    calmodulin-binding motif-   TESTI20045390//Immunoglobulin domain//Immunoglobulin    domain//Immunoglobulin domain//Immunoglobul in domain//Immunoglobul    in domain//Immunoglobulin domain//Immunoglobulin domain-   TESTI20046110//Extracellular link domain-   TESTI20046490//LIM domain containing proteins//Somatomedin B domain-   TESTI20046870//CRAL/TR10 domain.//CRAL/TR10 domain.//MSP (Major    sperm protein) domain-   TEST120046890//PHD-finger-   TESTI20049060//Immunoglobulin domain-   TESTI20049410//Proprotein convertase P-domain-   TESTI20050720//Coenzyme A transferase//Alpha-2-macroglobulin family    N-terminal region//Coenzyme A transferase-   TESTI20051730//Glutamine amidotransferases class-II//alpha/beta    hydrolase fold-   TESTI20053070//WD domain, G-beta repeat//WD domain, G-beta repeat-   TESTI20053950//IQ calmodulin-binding motif-   TESTI20055880//Serum amyloid A protein-   TESTI20056030//Myosin tail-   TESTI20057430//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//PHD-finger//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Transcription factor S-II    (TFIIS)//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   TESTI20057590//Leucine rich repeat C-terminal domain//Immunoglobulin    domain-   TESTI20057840//SAP domain//Zinc knuckle//Zinc finger, C3HC4 type    (RING finger)-   TESTI20057880//Zinc finger, C3HC4 type (RING finger)-   TESTI20058350//Polyomavirus coat protein//WD domain, G-beta    repeat//WD domain, G-beta repeat//WD domain, G-beta repeat//WD    domain, G-beta repeat//WD domain, G-beta repeat//WD domain, G-beta    repeat-   TESTI20058920//Tubulin/FtsZ family-   TESTI20059080//Thermophilic metalloprotease (M29)//Hyaluronidase-   TESTI20059480//Cyclic nucleotide-binding domain-   TESTI20059810//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Transcription factor S-II (TFIIS)//Zinc finger, C2H2 type//DM    DNA binding domain//Zinc finger, C2H2 type//Zinc finger, C2H2    type//BolA-like protein//Zinc finger, C2H2-type//Coronavirus M    matrix/glycoprotein//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   TESTI20060350//bZIP transcription factor-   TESTI20060830//ZAP domain//Ferric uptake regulator family//Peptidase    family M1//Piwi domain-   TESTI20061090//Keratin, high sulfur B2 protein-   TESTI20061200//Sugar (and other) transporter-   TESTI20064370//TPR Domain//TPR Domain//TPR Domain//TPR    Domain//Synaptobrevin-   TESTI20064530//WD domain, G-beta repeat//WD domain, G-beta    repeat//WD domain, G-beta repeat//WD domain, G-beta repeat//WD    domain, G-beta repeat//WD domain, G-beta repeat-   TESTI20064650//Myosin head (motor domain)-   TESTI20065650//G-protein alpha subunit-   TESTI20066150//Picornavirus 2B protein//Glutamine amidotransferase    class-I//Pancreatic hormone peptides-   TESTI20066330//Fibronectin type III domain-   TESTI20066650//RasGEF domain-   TESTI20067480//KRAB box//Zinc finger, C2H2 type//TRAF-type zinc    finger//Zinc finger, C2H2 type//Zinc finger, C2H2    type//PHD-finger//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//FYVE zinc finger//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   TESTI20068530//Zinc finger, C3HC4 type (RING finger)//PHD-finger-   TESTI20071130//ATP synthase Alpha chain, C terminal-   TESTI20071630//Glutamine synthetase//SCP-like extracellular protein-   TESTI20075240//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Putative zinc finger in N-recognin//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Transcription factor S-II (TFIIS)//Zinc finger,    C2H2 type//Zinc finger, C2H2 type-   TESTI20076570//Dual specificity phosphatase, catalytic domain-   TESTI20079220//KRAB box//Myb-like DNA-binding domain//Myb-like    DNA-binding domain//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//PHD-finger//Transcription factor S-II    (TFIIS)//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type-   TESTI20079980//PDZ domain (Also known as DHR or GLGF).//Domain found    in Dishevelled, Egl-10, and Pleckstrin-   TESTI20081890//PDZ domain (Also known as DHR or GLGF).-   TESTI20084250//Oxysterol-binding protein-   TESTI20086840//von Willebrand factor type A domain-   TESTI20088840//Zinc finger, C3HC4 type (RING    finger)//PHD-finger//Thymidine kinases//E7 protein, Early    protein//CONSTANS family zinc finger//B-box zinc finger.//SPRY    domain-   TESTI20092170//ENV polyprotein (coat polyprotein)-   TEST120095200//7TM chemoreceptor-   TESTI20095770//WD domain, G-beta repeat//WD domain, G-beta    repeat//WD domain, G-beta repeat//WD domain, G-beta repeat//WD    domain, G-beta repeat//WD domain, G-beta repeat//WD domain, G-beta    repeat-   TESTI20095880//Domain of unknown function DUF33//Penicillin    amidase//Formate/nitrite transporter//Sodium:galactoside symporter    family-   TESTI20099350//GGL domain//Clusterin//Biopterin-dependent aromatic    amino acid hydroxylase-   TESTI20100090//Lectin C-type domain-   TESTI20104090//TEA domain-   TESTI20105910//Notch (DSL) domain//Amiloride-sensitive sodium    channel-   TESTI20106170//WD domain, G-beta repeat//WD domain, G-beta    repeat//WD domain, G-beta repeat//WD domain, G-beta repeat//WD    domain, G-beta repeat-   TESTI20106820//Protein kinase C terminal domain-   TESTI20108060//Ser/Thr protein phosphatase-   TESTI20112540//Leucine Rich Repeat//Leucine Rich Repeat//Leucine    Rich Repeat//Leucine Rich Repeat//Chorismate synthase//UvrB/uvrC    motif-   TESTI20112860//Eukaryotic protein kinase domain-   TESTI20113940//Divalent cation transporter-   TEST120114480//Zinc finger, C4 type (two domains)//Zinc finger, C2HC    type//SAM domain (Sterile alpha motif)//Sterile alpha motif    (SAM)/Pointed domain-   TESTI20116050//UBX domain-   TESTI20120500//Kelch motif//Kelch motif-   TESTI20120900//DNA gyrase/topoisomerase IV, subunit A-   TESTI20121040//Protein phosphatase 2C//Protein phosphatase 2C-   TESTI20122070//ELM2 domain//Myb-like DNA-binding domain-   TESTI20125280//Immunoglobulin domain//Immunoglobulin domain-   TESTI20125920//PCI domain-   TESTI20126280//recA bacterial DNA recombination proteins-   TESTI20131440//Carboxypeptidase activation peptide//Zinc    carboxypeptidase-   TESTI20132310//Ubiquitin carboxyl-terminal hydrolase family 2-   TESTI20134680//MYND finger//B-box zinc finger.//CONSTANS family zinc    finger//Putative zinc finger in N-recognin-   TESTI20134970//Double-stranded RNA binding motif//Aldehyde oxidase    and xanthine dehydrogenase, C terminus//Adenosine-deaminase    (editase) domain-   TESTI20140970//Immunoglobulin domain-   TESTI20145780//Src homology domain 2-   TESTI20148380//TPR Domain//TPR Domain//TPR Domain//TPR Domain//TPR    Domain//TPR Domain//PPR repeat//Neuraminidases//ATP synthase Alpha    chain, C terminal//TPR Domain//TPR Domain//TPR Domain//TPR    Domain//PPR repeat//TPR Domain-   TESTI20150420//RhoGAP domain-   TESTI20150920//Leucine Rich Repeat//Leucine Rich Repeat//Leucine    Rich Repeat//Leucine Rich Repeat//Leucine Rich Repeat-   TESTI20153310//Intermediate filament tail domain-   TESTI20162780//Divalent cation transporter-   TESTI20162980//Ubiquitin family//Retroviral aspartyl    protease//Retroviral aspartyl protease-   TESTI20164210//Isocitrate and isopropylmalate    dehydrogenases//Ribosomal protein S27a//TILa domain//von Willebrand    factor type C domain-   TESTI20165990//Ribosomal protein L36-   TESTI20166290//Zinc finger, C2H2 type//FAD binding    domain//Phosphoenolpyruvate carboxykinase//Ribosomal protein S11-   TESTI20166670//Zinc finger C-x8-C-x5-C-x3-H type (and similar).-   TESTI20169500//GGL domain-   TESTI20170280//Flagellar L-ring protein-   TESTI20173960//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//PHD-finger//Zinc finger, C2H2 type//Zinc finger, C2H2 type t-   TESTI20179230//Dihydropyridine sensitive L-type calcium channel    (Beta subunit)-   TESTI20182760//Amiloride-sensitive sodium channel-   TESTI20183680//Gas vesicles protein GVPc repeated domain-   TESTI20184750//Laminin G domain//Thrombospondin N-terminal-like    domains//Laminin G domain-   TESTI20184760//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//PHD-finger//Transcription factor S-II    (TFIIS)//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type-   TESTI20186110//Divalent cation transporter//Translation initiation    factor IF-3//Divalent cation transporter-   TESTI20193080//Growth-Arrest-Specific Protein 2 Domain-   TESTI20194880//SAP domain-   TESTI20196690//Glycine cleavage T-protein (aminomethyl transferase)-   TEST120197030//Pancreatic hormone peptides-   TESTI20197600//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type-   TESTI20199110//Disintegrin-   TESTI20205100//DNA gyrase/topoisomerase IV, subunit A-   TESTI20205250//MORN motif//MORN motif//MORN motif//MORN motif//MORN    motif//MORN motif//MORN motif-   TESTI20207170//Nucleosome assembly protein (NAP)-   TESTI20210570//CRAL/TR10 domain.-   TESTI20212970//DEAD/DEAH box helicase//Helicases conserved    C-terminal domain-   TESTI20219110//Eukaryotic protein kinase domain-   TESTI20222030//Hemagglutinin//ATP synthase Alpha chain, C    terminal//AMP-binding enzyme-   TESTI20222460//Intermediate filament proteins-   TESTI20227380//DEAD/DEAH box helicase//Helicases conserved    C-terminal domain-   TESTI20228120//RhoGAP domain-   TESTI20228740//Zinc finger, C2H2 type-   TESTI20244220//Cecropin family//Fes/CIP4 homology domain//Hr1 repeat    motif//SH3 domain-   TESTI20244430//Ank repeat//Ank repeat//Ank repeat//SAM domain    (Sterile alpha motif)-   TESTI20244460//pKID domain//Adenylate kinase//Thymidylate    kinase//ATPases associated with various cellular activities (AAA)-   TESTI20246480//RNA recognition motif. (a.k.a. RRM, RBD, or RNP    domain)-   TESTI20251610//Chitin synthase//von Willebrand factor type A domain-   TESTI20252690//Domain found in Dishevelled, Egl-10, and Pleckstrin-   TESTI20254030//LIM domain containing proteins//LIM domain containing    proteins//Villin headpiece domain-   TESTI20254990//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type-   TESTI20255460//ZAP domain//Piwi domain-   TESTI20257910//Class I Histocompatibility antigen, domains alpha 1    and 2//Immunoglobulin domain-   TESTI20258720//Ank repeat//Ank repeat//Ank repeat-   TESTI20259110//Zinc finger, C3HC4 type (RING finger)//PHD-finger-   TESTI20261040//DNA polymerase (viral) C-terminal domain-   TESTI20261160//PH domain-   TESTI20261680//Hsp20/alpha crystallin family//Granulins-   TESTI20262150//Ion transport protein-   TESTI20262940//Phosphofructokinase-   TESTI20264530//WD domain, G-beta repeat//WD domain, G-beta    repeat//WD domain, G-beta repeat//WD domain, G-beta repeat//WD    domain, G-beta repeat//C. elegans integral membrane protein Srb//WD    domain, G-beta repeat//WD domain, G-beta repeat//SAM domain (Sterile    alpha motif)//Sterile alpha motif (SAM)/Pointed domain-   TESTI20264910//Uteroglobin family-   TESTI20266050//Zinc finger, C3HC4 type (RING finger)//SPRY domain-   TESTI20274960//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Transcription factor S-II (TFIIS)//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   TESTI20278280//PMP-22/EMP/MP20/Claudin family-   TESTI20282530//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type-   TESTI20284260//Histone-like transcription factor (CBF/NF-Y) and    archaeal histone//Core histone H2A/H₂B/H3/H4-   TESTI20285230//Adenosine-deaminase (editase) domain-   THYMU10004280//NHL-repeat//NHL repeat-   THYMU20006020//Isocitrate and isopropylmalate dehydrogenases-   THYMU20009500//TPR Domain-   THYMU20013250//LIM domain containing proteins//RI01/ZK632.3/MJ0444    family//Eukaryotic protein kinase domain-   THYMU20018250//TPR Domain-   THYMU20019260//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type-   THYMU20021090//SAM domain (Sterile alpha motif)//Sterile alpha motif    (SAM)/Pointed domain-   THYMU20028150//Immunoglobulin domain//Immunoglobulin    domain//Immunoglobulin domain//Immunoglobulin domain-   THYMU20028410//BRCA1 C Terminus (BRCT) domain//BRCA1 C Terminus    (BRCT) domain-   THYMU20031330//4Fe-4S iron sulfur cluster binding proteins,    NifH/frxC family-   THYMU20032820//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type-   THYMU20039320//WD domain, G-beta repeat//WD domain, G-beta    repeat//WD domain, G-beta repeat//WD domain, G-beta repeat-   THYMU20046350//Cytochrome C and Quinol oxidase polypeptide I-   THYMU20049060//RNA recognition motif. (a.k.a. RRM, RBD, or RNP    domain)-   THYMU20052830//Immunoglobulin domain//Immunoglobulin    domain//Immunoglobulin domain//Immunoglobulin domain-   THYMU20055450//Zona pellucida-like domain-   THYMU20055460//Putative esterase-   THYMU20055760//Na+/K+ ATPase C-terminus//Phospholipase A2-   THYMU20062770//Zona pellucida-like domain-   THYMU20063650//Ribulose-phosphate 3 epimerase    family//Indole-3-glycerol phosphate synthases-   THYMU20066660//DEAD/DEAH box helicase-   THYMU20070250//Transketolase//Dehydrogenase E1    component//Transketolase-   THYMU20071120//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type-   THYMU20077250//HMG (high mobility group) box-   THYMU20081110//LIM domain containing proteins-   THYMU20083390//11S plant seed storage protein-   THYMU20090230//RNA recognition motif. (a.k.a. RRM, RBD, or RNP    domain)-   THYMU20095920//Iron hydrogenase small subunit-   THYMU20097920//PH domain//FERM domain (Band 4.1 family)-   THYMU20098350//bZIP transcription factor//bZIP transcription    factor//Tubulin/FtsZ family//Intermediate filament proteins-   THYMU20099060//Immunoglobulin domain//Immunoglobulin    domain//Immunoglobulin domain//Immunoglobulin domain//Immunoglobulin    domain-   THYMU20100940//Protein of unknown function DUF132-   THYMU20104480//RNA recognition motif. (a.k.a. RRM, RBD, or RNP    domain)-   THYMU20106990//PH domain-   THYMU20110720//Aminotransferases class-III pyridoxal-phosphate-   THYMU20112590//Acyl-CoA dehydrogenase//Adaptin N terminal region-   THYMU20120240//Ubiquitin carboxyl-terminal hydrolases family    2//Ubiquitin carboxyl-terminal hydrolase family 2-   THYMU20120730//Aldehyde dehydrogenase family-   THYMU20121040//bZIP transcription factor//EF-1 guanine nucleotide    exchange domain-   THYMU20139160//Uncharacterized protein family UPF0031-   THYMU20143230//EGF-like domain//Extracellular link domain//Fasciclin    domain-   THYMU20145990//SH3 domain-   THYMU20153210//7 transmembrane receptor (Secretin family)-   THYMU20170230//Glycine cleavage T-protein (aminomethyl transferase)-   THYMU20176010//WD domain, G-beta repeat//PQQ enzyme repeat//WD    domain, G-beta repeat//WD domain, G-beta repeat//WD domain, G-beta    repeat//WD domain, G-beta repeat//WD domain, G-beta repeat//WD    domain, G-beta repeat//WD domain, G-beta repeat-   THYMU20178440//Immunoglobulin domain//Immunoglobulin    domain//Immunoglobulin domain//Immunoglobulin domain-   THYMU20184550//HSF-type DNA-binding domain//bZIP transcription    factor-   THYMU20191970//Cadherin domain//Cadherin domain//Cadherin    domain//Cadherin domain-   TKIDN10000620//Thioredoxin-   TKIDN10001920//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type-   TRACH20011010//5′-nucleotidase-   TRACH20021380//Copper/zinc superoxide dismutase (SODC)//Adenylate    and Guanylate cyclase catalytic domain//Adenylate and Guanylate    cyclase catalytic domain-   TRACH20029880//MORN motif//MORN motif//Penicillin amidase//Bacterial    regulatory proteins, lacI family//Vacuolar sorting protein 9 (VPS9)    domain-   TRACH20040390//Pumilio-family RNA binding domains (aka PUM-HD,    Pumilio homology domain)//Pumilio-family RNA binding domains (aka    PUM-HID, Pumilio homology domain)//Pumilio-family RNA binding    domains (aka PUM-HD, Pumilio homology domain)//Pumilio-family RNA    binding domains (aka PUM-HD, Pumilio homology    domain)//Pumilio-family RNA binding domains (aka PUM-HD, Pumilio    homology domain)//Pumilio-family RNA binding domains (aka PUM-HD,    Pumilio homology domain)//Pumilio-family RNA binding domains (aka    PUM-HD, Pumilio homology domain)//Pumilio-family RNA binding domains    (aka PUM-HD, Pumilio homology domain)-   TRACH20043360//Kinesin motor domain//Caspase recruitment    domain//Ribosomal protein L35-   TRACH20058000//Fibronectin type III domain-   TRACH20090060//C2 domain-   TRACH20091070//Aldehyde dehydrogenase family-   TRACH20093400//Adaptin N terminal region-   TRACH20098510//Ribosomal L29 protein-   TRACH20104510//Uncharacterized protein family UPF0005-   TRACH20108240//RNA recognition motif. (a.k.a. RRM, RBD, or RNP    domain)//RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)-   TRACH20113020//AIR synthase related protein-   TRACH20122980//TPR Domain//TPR Domain//TPR Domain//TPR Domain//TPR    Domain-   TRACH20131230//PH domain//Oxysterol-binding protein-   TRACH20139280//PX domain-   TRACH20143710//Leucine Rich Repeat//Leucine Rich Repeat//Leucine    Rich Repeat-   TRACH20149500//Zinc finger//Plexin repeat//Cysteine rich    repeat//Intermediate filament proteins-   TRACH20149740//Sodium:dicarboxylate symporter family-   TRACH20163470//Putative integral membrane protein DUF46//Sugar (and    other) transporter//Sodium:galactoside symporter family-   TRACH20164100//Retroviral aspartyl protease-   TRACH20164810//D-isomer specific 2-hydroxyacid dehydrogenases-   TRACH20167090//Chitinases, family 2-   TRACH20170860//Immunoglobulin domain//Immunoglobulin    domain//Immunoglobulin domain//Immunoglobulin domain-   TRACH20188350//Tropomyosins-   TRACH20190460//Lipase (class 3)-   UTERU20000950//WD domain, G-beta repeat//WD domain, G-beta    repeat//WD domain, G-beta repeat//WD domain, G-beta repeat//WD    domain, G-beta repeat-   UTERU20016580//Zinc finger present in dystrophin, CBP/p300//Myb-like    DNA-binding domain-   UTERU20026620//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type-   UTERU20041630//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Transcription factor S-II (TFIIS)//Zinc finger, C2H2    type//Zinc finger, C2H2 type-   UTERU20083020//Domain of unknown function DUF71-   UTERU20086530//Lipocalin/cytosolic fatty-acid binding protein family-   UTERU20087070//Sushi domain (SCR repeat)//Trypsin-   UTERU20089390//TPR Domain//TPR Domain//TPR Domain//TPR Domain//TPR    Domain//TPR Domain//TPR Domain//TPR Domain-   UTERU20089620//Fringe-like-   UTERU20099040//Cation efflux family-   UTERU20099510//KRAB box//Zinc finger, C2H2 type//Zinc finger, C2H2    type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc finger,    C2H2 type//Zinc finger, C2H2 type//Zinc finger, C2H2 type//Zinc    finger, C2H2 type//Zinc finger, C2H2 type//PHD-finger//Zinc finger,    C2H2 type-   UTERU20104310//RNA polymerases K/14 to 18 kDa subunit-   UTERU20121140//Rhodanese-like domain-   UTERU20122520//FERM domain (Band 4.1 family)//FERM domain (Band 4.1    family)-   UTERU20127030//Xylose isomerase//ApbE family-   UTERU20127150//Translation initiation factor IF-3//Divalent cation    transporter-   UTERU20128560//Domain of unknown function DUF28-   UTERU20132620//HMG14 and HMG17-   UTERU20139760//Mitochondrial carrier proteins//Mitochondrial carrier    proteins-   UTERU20168960//PH domain//Methanol dehydrogenase beta subunit-   UTERU20181270//Zinc knuckle-   UTERU20185220//Bromodomain

EXAMPLE 6 Functional Categorization Based on the Full-Length NucleotideSequences

The functional prediction and categorization of the proteins encoded bythe clones were carried out based on the result of homology search ofthe databases of GenBank, Swiss-Prot, UniGene and nr (see the HomologySearch Result Data) for the full-length nucleotide sequences and theresult of domain search of the amino acid sequences deduced from thefull-length nucleotide sequences (see Example 5).

The clone predicted to belong to the category of secretoryprotein/membrane protein means a clone having hit data with someannotation, such as growth factor, cytokine, hormone, signal,transmembrane, membrane, extracellular matrix, receptor, G-proteincoupled receptor, ionic channel, voltage-gated channel, calcium channel,cell adhesion, collagen, connective tissue, etc., suggesting that it isa secretory or membrane protein, or means a clone in which the presenceof nucleotide sequence encoding a signal sequence or transmembranedomain was suggested by the results of PSORT and SOSUI analyses fordeduced ORF.

The clone predicted to belong to the category of glycoprotein-relatedprotein means a clone having hit data with some annotation, such asglycoprotein, suggesting that the clone encodes a glycoprotein-relatedprotein.

The clone predicted to belong to the category of signaltransduction-related protein means a clone having hit data with someannotation, such as serine/threonine-protein kinase, tyrosine-proteinkinase, SH3 domain, SH2 domain, etc., suggesting that the clone encodesa signal transduction-related protein.

The clone predicted to belong to the category of transcription-relatedprotein means a clone having hit data with some annotation, such astranscription regulation, zinc finger, homeobox, etc., suggesting thatthe clone encodes a transcription-related protein.

The clone predicted to belong to the category of disease-related proteinmeans a clone having hit data with some annotation, such as diseasemutation, syndrome, etc., suggesting that the clone encodes adisease-related protein, or means a clone whose full-length nucleotidesequence has hit data for Swiss-Prot, GenBank, or UniGene, where the hitdata corresponds to genes or proteins which have been deposited in theOnline Mendelian Inheritance in Man (OMIM)(http://www.ncbi.nlm.nih.gov/Omim/), which is the human gene and diseasedatabase.

The clone predicted to belong to the category of enzyme and/ormetabolism-related protein means a clone having hit data with someannotation, such as metabolism, oxidoreductase, E. C. No. (Enzymecommission number), etc., suggesting that the clone encodes an enzymeand/or metabolism-related protein.

The clone predicted to belong to the category of cell division and/orcell proliferation-related protein means a clone having hit data withsome annotation, such as cell division, cell cycle, mitosis, chromosomalprotein, cell growth, apoptosis, etc., suggesting that the clone encodesa cell division and/or cell proliferation-related protein.

The clone predicted to belong to the category of cytoskeleton-relatedprotein means a clone having hit data with some annotation, such asstructural protein, cytoskeleton, actin-binding, microtubles, etc.,suggesting that the clone encodes a cytoskeleton-related protein.

The clone which is predicted to belong to the category of nuclearprotein and/or RNA synthesis-related protein means a clone having hitdata with some annotation, such as nuclear protein, RNA splicing, RNAprocessing, RNA helicase, polyadenylation, etc., suggesting that theclone encodes a nuclear protein and/or RNA synthesis-related protein.

The clone predicted to belong to the category of protein synthesisand/or transport-related protein means a clone having hit data with someannotation, such as translation regulation, protein biosynthesis,amino-acid biosynthesis, ribosomal protein, protein transport, signalrecognition particle, etc., suggesting that the clone encodes a proteinsynthesis and/or transport-related protein.

The clone predicted to belong to the category of cellulardefense-related protein means a clone having hit data with someannotation, such as heat shock, DNA repair, DNA damage, etc., suggestingthat the clone encodes a cellular defense-related protein.

The clone predicted to belong to the category of development and/ordifferentiation-related proteins means a clone having hit data with someannotation, such as developmental protein, etc., suggesting that theclone encodes a development and/or differentiation-related protein.

The clone predicted to belong to the category of DNA-binding and/orRNA-binding protein means a clone having hit data with some annotation,such as DNA-binding, RNA-binding, etc.

The clone predicted to belong to the category of ATP-binding and/orGTP-binding protein means a clone having hit data with some annotation,such as ATP-binding, GTP-binding, etc.

In this functional categorization, when a single clone corresponded tomultiple categories of those shown above, the clone was assigned to themultiple categories. However, the function of a protein is notrestricted to the functional category in this classification, and thereis the possibility that other functions are newly assigned to theprotein.

The clones predicted to belong to the category of secretory proteinand/or membrane protein are the following 516 clones. ADRGL20020290,ADRGL20021910, ADRGL20036380, ADRGL20036840, ADRGL20059610,ADRGL20063770, ADRGL20066770, ASTRO20010010, ASTRO20020240,ASTRO20045840, ASTRO20053430, ASTRO20055530, ASTRO20055570,ASTRO20055930, ASTRO20088950, ASTRO20091180, BNGH420021680,BNGH420023870, BNGH420046790, BNGH420052350, BNGH420059680,BNGH420075940, BNGH420077980, BRACE10000510, BRACE20051930,BRACE20052530, BRACE20054080, BRACE20066360, BRACE20068710,BRACE20069000, BRACE20069110, BRACE20194670, BRACE20204670,BRACE20216950, BRAMY10001730, BRAMY20003880, BRAMY20013670,BRAMY20024790, BRAMY20027390, BRAMY20028530, BRAMY20035380,BRAMY20044920, BRAMY20045210, BRAMY20047560, BRAMY20050940,BRAMY20053910, BRAMY20055760, BRAMY20072440, BRAMY20083820,BRAMY20089770, BRAMY20091230, BRAMY20094890, BRAMY20096930,BRAMY20118410, BRAMY20123400, BRAMY20125550, BRAMY20127310,BRAMY20127760, BRAMY20135720, BRAMY20137360, BRAMY20139440,BRAMY20152510, BRAMY20194680, BRAMY20204270, BRAMY20225320,BRAMY20237190, BRAMY20245140, BRAMY20251750, BRAMY20285650,BRAWH20020470, BRAWH20021910, BRAWH20026010, BRAWH20030000,BRAWH20039640, BRAWH20055330, BRAWH20078620, BRAWH20093070,BRAWH20185270, BRCAN10000760, BRCAN10001680, BRCAN20001480,BRCAN20004180, BRCAN20005230, BRCOC20000470, BRCOC20003600,BRHIP10000720, BRHIP10001040, BRHIP20000210, BRSSN20001970,BRSSN20074640, BRSSN20091190, CD34C20001750, CTONG20017490,CTONG20036990, CTONG20041260, CTONG20044870, CTONG20045500,CTONG20049480, CTONG20051450, CTONG20055850, CTONG20056150,CTONG20059130, CTONG20060040, CTONG20063770, CTONG20065680,CTONG20068360, CTONG20069320, CTONG20071680, CTONG20076810,CTONG20078340, CTONG20079590, CTONG20083980, CTONG20084020,CTONG20085210, CTONG20167750, CTONG20168240, CTONG20179890,CTONG20183830, CTONG20184830, DFNES20018000, DFNES20029660,DFNES20057660, DFNES20072990, DFNES20080880, FCBBF20018680,FCBBF20029280, FCBBF20032930, FCBBF20036360, FCBBF20054390,FCBBF30004340, FCBBF30022680, FCBBF30029250, FCBBF30042610,FCBBF30062490, FCBBF30075970, FCBBF30078600, FCBBF30091520,FCBBF30095410, FCBBF30105440, FCBBF30118670, FCBBF30132660,FCBBF30135890, FCBBF30145670, FCBBF30164510, FCBBF30169870,FCBBF30171230, FCBBF30172330, FCBBF30177290, FCBBF30179740,FCBBF30195690, FCBBF30197840, FCBBF30212210, FCBBF30223110,FCBBF30223210, FCBBF30225930, FCBBF30230610, FCBBF30260480,FCBBF30266510, FCBBF30287940, FCBBF50000610, FCBBF50004950,FEBRA20007820, FEBRA20018670, FEBRA20031280, FEBRA20031810,FEBRA20038220, FEBRA20039260, FEBRA20040230, FEBRA20040560,FEBRA20046280, FEBRA20080860, FEBRA20084750, FEBRA20088810,FEBRA20115930, FEBRA20116650, FEBRA20121950, FEBRA20141980,FEBRA20177800, FEBRA20182030, FEBRA20191720, HCHON10001660,HCHON20015050, HEART10001490, HEART20031680, HHDPC10001140,HHDPC20051850, HHDPC20082790, HHDPC20088160, HLUNG20015070,HLUNG20015180, HLUNG20020850, HLUNG20029490, HLUNG20032460,HLUNG20033350, HLUNG20034970, HLUNG20037160, HLUNG20041540,HLUNG20042730, HLUNG20050760, HLUNG20052300, HLUNG20060670,HLUNG20065990, HLUNG20074330, HLUNG20081390, HLUNG20088750,HLUNG20092530, KIDNE20016360, KIDNE20083150, KIDNE20084030,KIDNE20084040, KIDNE20084800, KIDNE20086490, KIDNE20086660,KIDNE20094670, KIDNE20134130, KIDNE20142900, KIDNE20143200,KIDNE20148080, KIDNE20160960, KIDNE20163710, KIDNE20169180,KIDNE20182540, KIDNE20186170, KIDNE20188630, KIDNE20189960,LIVER20007750, LIVER20010510, LIVER20010990, LIVER20026440,LIVER20030650, LIVER20038000, MESAN20007110, MESAN20008150,MESAN20021220, MESAN20027900, MESAN20058110, MESAN20059570,MESAN20060430, MESAN20067430, MESAN20084150, MESAN20095220,NT2NE20018740, NT2NE20021860, NT2NE20039210, NT2NE20053230,NT2NE20059210, NT2NE20064780, NT2NE20069580, NT2NE20080770,NT2NE20082130, NT2NE20092950, NT2NE20140130, NT2NE20145250,NT2NE20146510, NT2NE20152620, NT2NE20167660, NT2NE20181800,NT2RI20016240, NT2RI20021200, NT2RI20033920, NT2RP70003110,NT2RP70027790, NT2RP70031070, NT2RP70031480, NT2RP70056690,NT2RP70087140, NTONG20034540, NTONG20053630, OCBBF20000740,OCBBF20012520, OCBBF20109780, OCBBF20110210, OCBBF20110730,OCBBF20112280, OCBBF20118720, OCBBF20120010, OCBBF20123200,OCBBF20155030, OCBBF20165900, OCBBF20165910, OCBBF20170350,OCBBF20176650, OCBBF20185630, OCBBF20191950, PANCR10000860,PEBLM20001800, PLACE50001290, PLACE60004260, PLACE60006300,PLACE60053280, PLACE60055590, PLACE60056910, PLACE60057860,PLACE60061370, PLACE60064740, PLACE60070500, PLACE60087680,PLACE60104630, PLACE60107010, PLACE60113340, PLACE60138840,PLACE60154450, PLACE60184870, PROST10001100, PROST20011160,PROST20014150, PROST20035830, PROST20045700, PROST20050390,PROST20065100, PROST20073280, PROST20082430, PROST20084680,PROST20084720, PROST20099090, PROST20105450, PROST20106060,PROST20108850, PROST20110120, PROST20114100, PROST20146590,PROST20152510, PROST20168600, PUAEN10000870, SKMUS20006790,SKMUS20020770, SKMUS20073150, SKMUS20091900, SKNMC20006350,SKNSH20094350, SMINT20006090, SMINT20008110, SMINT20024140,SMINT20028840, SMINT20045470, SMINT20077960, SMINT20081330,SMINT20086250, SMINT20088440, SMINT20088690, SMINT20092160,SPLEN20015100, SPLEN20017610, SPLEN20017810, SPLEN20024190,SPLEN20024620, SPLEN20054500, SPLEN20058180, SPLEN20063890,SPLEN20073880, SPLEN20080070, SPLEN20090880, SPLEN20101950,SPLEN20104690, SPLEN20105100, SPLEN20108000, SPLEN20110180,SPLEN20110860, SPLEN20118050, SPLEN20121790, SPLEN20125230,SPLEN20136700, SPLEN20138600, SPLEN20139100, SPLEN20175920,SPLEN20177400, SPLEN20182850, SPLEN20183020, SPLEN20183950,SPLEN20190080, SPLEN20190770, SPLEN20193230, SPLEN20193490,SPLEN20193790, SPLEN20201830, SPLEN20204670, TESOP10000350,TESTI10000190, TESTI20006160, TESTI20029100, TESTI20031310,TESTI20032770, TESTI20038240, TESTI20043130, TESTI20043220,TESTI20045390, TESTI20046540, TESTI20046870, TESTI20047370,TESTI20050400, TESTI20051200, TESTI20051730, TESTI20053260,TESTI20053780, TESTI20057200, TESTI20057590, TESTI20059080,TESTI20061200, TESTI20062120, TESTI20063330, TESTI20063410,TESTI20063600, TESTI20066330, TESTI20068530, TESTI20070400,TESTI20070740, TESTI20073460, TESTI20086840, TESTI20095200,TESTI20095440, TESTI20095880, TESTI20100090, TESTI20102390,TESTI20105910, TESTI20113940, TESTI20116120, TESTI20121040,TESTI20121710, TESTI20131440, TESTI20142540, TESTI20149880,TESTI20151800, TESTI20162780, TESTI20170170, TESTI20173050,TESTI20182760, TESTI20183680, TESTI20184750, TESTI20186110,TESTI20198540, TESTI20199110, TESTI20202830, TESTI20204260,TESTI20210030, TESTI20214630, TESTI20219110, TESTI20244730,TESTI20245600, TESTI20245860, TESTI20246410, TESTI20251610,TESTI20257910, TESTI20260640, TESTI20261040, TESTI20262150,TESTI20262940, TESTI20264910, TESTI20271790, TESTI20278280,TESTI20282420, TESTI20282900, TESTI20286590, THYMU20007020,THYMU20012020, THYMU20017270, THYMU20020800, THYMU20025480,THYMU20028150, THYMU20030690, THYMU20034790, THYMU20046350,THYMU20046770, THYMU20050010, THYMU20052830, THYMU20054800,THYMU20055740, THYMU20055760, THYMU20062770, THYMU20078240,THYMU20079690, THYMU20083390, THYMU20087270, THYMU20100940,THYMU20115380, THYMU20137050, THYMU20137570, THYMU20143230,THYMU20150190, THYMU20153210, THYMU20154790, THYMU20163600,THYMU20171580, THYMU20178440, THYMU20185470, TRACH20011010,TRACH20011540, TRACH20021380, TRACH20073990, TRACH20081270,TRACH20090060, TRACH20149720, TRACH20149740, TRACH20159390,TRACH20163470, TRACH20165330, TRACH20167090, TRACH20173680,TRACH20190460, UMVEN10001380, UTERU20035770, UTERU20040150,UTERU20045200, UTERU20064120, UTERU20086530, UTERU20087070,UTERU20087850, UTERU20089300, UTERU20089620, UTERU20095100,UTERU20099040, UTERU20103200, UTERU20125810, UTERU20127030,UTERU20127150, UTERU20139760, UTERU20188840

The clones predicted to belong to the category of glycoprotein-relatedprotein are the following 121 clones. ADRGL20020290, ADRGL20036840,ADRGL20059610, ADRGL20066770, ASTRO20055570, BNGH420046790,BNGH420077980, BRACE20051930, BRACE20069000, BRACE20204670,BRACE20216950, BRAMY20013670, BRAMY20089770, BRAMY20251210,BRAWH20039640, BRCAN10000760, BRCAN20005230, BRCOC20003600,CD34C20001750, CTONG20017490, CTONG20036990, CTONG20045500,CTONG20059130, CTONG20079590, CTONG20085210, CTONG20184830,DFNES20018000, DFNES20080880, FCBBF30004340, FCBBF30029250,FCBBF30062490, FCBBF30091520, FCBBF30164510, FCBBF30171230,FCBBF30195690, FCBBF30223210, FEBRA20038220, HCHON20015050,HLUNG20015070, HLUNG20032460, HLUNG20037160, HLUNG20041540,KIDNE20142900, KIDNE20169180, KIDNE20186170, KIDNE20189960,MESAN20021220, MESAN20058110, NT2NE20064780, NT2NE20140130,NT2NE20155650, NT2RP70056690, NTONG20053630, OCBBF20000740,OCBBF20012520, OCBBF20110210, OCBBF20120010, OCBBF20165900,OCBBF20165910, OCBBF20191950, PEBLM20001800, PLACE60004260,PLACE60087680, PLACE60113340, PLACE60184870, PROST20033240,PROST20099090, PROST20108850, PROST20146590, SKMUS20073150,SKNMC20006350, SMINT20028840, SMINT20056230, SMINT20083290,SMINT20091190, SPLEN20024620, SPLEN20063890, SPLEN20080070,SPLEN20090880, SPLEN20118050, SPLEN20139100, SPLEN20183020,SPLEN20201830, TESTI10000190, TESTI20031310, TESTI20043990,TESTI20045390, TESTI20051200, TESTI20057590, TESTI20059080,TESTI20066330, TESTI20086840, TESTI20100090, TESTI20105910,TESTI20154370, TESTI20164210, TESTI20182760, TESTI20184750,TESTI20199110, TESTI20219110, TESTI20220230, TESTI20245600,TESTI20251610, TESTI20257910, TESTI20286590, THYMU20024500,THYMU20028150, THYMU20052830, THYMU20062770, THYMU20099060,THYMU20170080, THYMU20178440, TRACH20011010, TRACH20011540,TRACH20021380, TRACH20149740, TRACH20170860, TRACH20190460,UTERU20086530, UTERU20087070, UTERU20127030

The clones predicted to belong to the category of signaltransduction-related protein are the following 88 clones. ASTRO20050810,ASTRO20052420, ASTRO20085080, ASTRO20090680, BNGH420008150,BNGH420015760, BNGH420035290, BNGH420086030, BRAMY20035830,BRAMY20043630, BRAMY20118490, BRAMY20206340, BRAMY20244490,BRAMY20251210, BRAMY20263000, BRAWH20093040, BRAWH20190550,CTONG20004520, CTONG20029030, CTONG20030280, CTONG20063930,CTONG20070720, CTONG20189000, FCBBF30001100, FCBBF30076310,FCBBF30100080, FCBBF30143550, FCBBF30153170, FCBBF30175350,FCBBF30250980, FEBRA20090160, FEBRA20173330, HCHON20000870,HLUNG20011260, HLUNG20084790, KIDNE20089870, KIDNE20160360,LIVER20011640, MESAN20021130, MESAN20027240, MESAN20065990,NT2NE20018890, NT2NE20042550, NT2RP70075800, NTONG20043080,NTONG20048440, PLACE60071800, PROST20033240, PROST20052850,PROST20065790, PROST20075280, SKNSH20052400, SKNSH20057920,SMINT20006020, SMINT20035050, SPLEN20023540, SPLEN20039180,SPLEN20048800, SPLEN20049840, SPLEN20054160, SPLEN20085910,SPLEN20191020, SPLEN20198390, TESTI20046490, TESTI20049060,TESTI20053070, TESTI20066650, TESTI20081890, TESTI20095770,TESTI20106820, TESTI20112860, TESTI20145780, TESTI20150420,TESTI20168880, TESTI20205250, TESTI20228120, TESTI20244220,TESTI20244460, TESTI20251740, TESTI20261160, TESTI20264530,THYMU20013250, THYMU20039320, THYMU20106990, THYMU20145990,THYMU20170080, THYMU20176010, TRACH20188350

The clones predicted to belong to the category of transcription-relatedprotein are the following 143 clones. ASTRO20038400, ASTRO20075150,BNGH420070370, BNGH420074600, BNGH420087430, BRACE20003310,BRACE20061620, BRAMY20001510, BRAMY20040580, BRAMY20076100,BRAMY20111780, BRAWH20040680, BRAWH20050740, BRAWH20080580,BRAWH20082920, BRAWH20095900, BRSSN20066440, CTONG20020950,CTONG20044230, CTONG20053990, CTONG20072930, CTONG20074000,CTONG20084660, CTONG20186370, CTONG20186520, DFNES20028170,DFNES20046840, DFNES20073320, FCBBF30003610, FCBBF30019140,FCBBF30021900, FCBBF30093170, FCBBF30114850, FCBBF30129010,FCBBF30136230, FCBBF30143550, FCBBF30220050, FCBBF30228940,FCBBF30263080, FCBBF30285930, FCBBF50003530, FEBRA20026820,FEBRA20027070, FEBRA20046510, FEBRA20057010, FEBRA20063720,FEBRA20170240, HCHON10000150, HCHON20002650, HEART20019310,HLUNG20014590, HLUNG20028110, HLUNG20063700, KIDNE20140870,LIVER20006260, MESAN20016270, MESAN20038520, NT2NE20038870,NT2NE20053950, NT2NE20060750, NT2NE20061030, NT2NE20079670,NT2NE20082600, NT2RP70001120, NT2RP70029780, NT2RP70046410,NT2RP70057500, NT2RP70075300, NT2RP70090870, OCBBF20116250,OCBBF20120950, OCBBF20121910, OCBBF20156450, OCBBF20157970,OCBBF20166900, OCBBF20175360, OCBBF20177540, PEBLM20003260,PLACE60052940, PLACE60066970, PLACE60122970, PLACE60150510,PLACE60177880, PROST20007170, PROST20024250, PROST20035170,PROST20127450, PROST20151370, PROST20155370, PUAEN10000650,PUAEN20003120, SMINT20011950, SMINT20026200, SMINT20030740,SMINT20039050, SMINT20044140, SMINT20086720, SPLEN20042200,SPLEN20043680, SPLEN20055600, SPLEN20059270, SPLEN20063250,SPLEN20098030, SPLEN20197930, TESTI10001570, TESTI20057430,TESTI20057840, TESTI20059810, TESTI20067480, TESTI20068790,TESTI20075240, TESTI20079220, TESTI20088840, TESTI20104090,TESTI20122070, TESTI20166670, TESTI20171070, TESTI20173960,TESTI20184760, TESTI20194880, TESTI20197600, TESTI20228740,TESTI20254030, TESTI20254990, TESTI20266050, TESTI20274960,TESTI20282530, THYMU10004280, THYMU20019260, THYMU20032820,THYMU20071120, THYMU20077250, TKIDN10001920, UTERU20016580,UTERU20026620, UTERU20041630, UTERU20094830, UTERU20099510,UTERU20101150, UTERU20169020, UTERU20177150, UTERU20185220,UTERU20188670

The clones predicted to belong to the category of disease-relatedprotein are the following 331 clones. ADRGL20020290, ADRGL20021910,ADRGL20026790, ADRGL20036840, ADRGL20059610, ADRGL20066770,ASTRO20038400, ASTRO20052420, ASTRO20055570, ASTRO20075150,ASTRO20088950, BNGH420008150, BNGH420086030, BRACE10000510,BRACE20003310, BRACE20069000, BRACE20097540, BRACE20194670,BRACE20196180, BRACE20204670, BRACE20216950, BRAMY20003540,BRAMY20005080, BRAMY20035830, BRAMY20040580, BRAMY20043630,BRAMY20044920, BRAMY20051820, BRAMY20056620, BRAMY20089770,BRAMY20111780, BRAMY20152510, BRAMY20190550, BRAMY20221600,BRAMY20227860, BRAMY20274510, BRAWH20082920, BRAWH20093040,BRAWH20095900, BRAWH20190530, BRAWH20191980, BRCAN10000760,BRCAN10001050, BRCAN20005230, BRSSN20066440, CTONG20004520,CTONG20029030, CTONG20042640, CTONG20045500, CTONG20052780,CTONG20053990, CTONG20070780, CTONG20070910, CTONG20072930,CTONG20083980, CTONG20084660, CTONG20165750, CTONG20169040,CTONG20183430, CTONG20183830, CTONG20186290, CTONG20189000,DFNES20016470, DFNES20025500, DFNES20046840, DFNES20055400,DFNES20080880, FCBBF10000230, FCBBF20035490, FCBBF20066340,FCBBF30002270, FCBBF30002280, FCBBF30019140, FCBBF30053300,FCBBF30071500, FCBBF30072440, FCBBF30076310, FCBBF30080730,FCBBF30100080, FCBBF30115920, FCBBF30118670, FCBBF30129010,FCBBF30132050, FCBBF30136230, FCBBF30153170, FCBBF30164510,FCBBF30166220, FCBBF30171230, FCBBF30175350, FCBBF30194550,FCBBF30220050, FCBBF30223210, FCBBF30259050, FCBBF30263080,FCBBF30275590, FCBBF50001650, FEBRA20027070, FEBRA20045380,FEBRA20046200, FEBRA20046510, FEBRA20057010, FEBRA20063720,FEBRA20078800, FEBRA20087550, FEBRA20088810, FEBRA20090160,FEBRA20092760, FEBRA20151750, FEBRA20170240, FEBRA20173330,FEBRA20191720, HCHON10000150, HCHON20015050, HEART20009590,HEART20022200, HEART20063100, HHDPC20081230, HLUNG20008460,HLUNG20014590, HLUNG20032460, HLUNG20063700, HLUNG20065990,HLUNG20069350, HLUNG20081530, HLUNG20082350, HLUNG20083330,HLUNG20085210, KIDNE20081170, KIDNE20084040, KIDNE20088240,KIDNE20089870, KIDNE20133460, KIDNE20134890, KIDNE20141700,KIDNE20142900, KIDNE20150730, KIDNE20152440, KIDNE20160360,KIDNE20165390, KIDNE20169180, KIDNE20173430, KIDNE20189960,LIVER20026440, MESAN20006200, MESAN20021130, MESAN20033220,MESAN20056890, MESAN20057240, MESAN20065990, MESAN20067430,MESAN20069530, NESOP20004520, NT2NE20018890, NT2NE20026200,NT2NE20037050, NT2NE20053950, NT2NE20061030, NT2NE20111190,NT2NE20117580, NT2NE20119980, NT2NE20140130, NT2NE20141040,NT2RI20093010, NT2RP70003110, NT2RP70046410, NT2RP70075300,NTONG20032100, NTONG20034540, OCBBF20000740, OCBBF20012520,OCBBF20111600, OCBBF20120010, OCBBF20156450, OCBBF20157970,OCBBF20191950, PEBLM20001800, PEBLM20003260, PLACE60004260,PLACE60012620, PLACE60054230, PLACE60054870, PLACE60062660,PLACE60087680, PLACE60184870, PROST20015210, PROST20024250,PROST20036350, PROST20050390, PROST20058860, PROST20063430,PROST20065790, PROST20084720, PROST20099090, PROST20120070,PROST20127450, PROST20146590, PROST20152510, PROST20168600,PUAEN10000650, PUAEN20003120, SKMUS20008730, SKMUS20017400,SKMUS20040440, SKMUS20073590, SKMUS20079150, SKNSH20009710,SMINT20002320, SMINT20007470, SMINT20008110, SMINT20011950,SMINT20016150, SMINT20026200, SMINT20030740, SMINT20049920,SMINT20077960, SMINT20083290, SMINT20086250, SMINT20089600,SMINT20091190, SPLEN20023540, SPLEN20024190, SPLEN20042200,SPLEN20043680, SPLEN20055600, SPLEN20057830, SPLEN20059270,SPLEN20063890, SPLEN20073500, SPLEN20080070, SPLEN20085910,SPLEN20090880, SPLEN20098030, SPLEN20118050, SPLEN20136730,SPLEN20138600, SPLEN20139100, SPLEN20139360, SPLEN20180980,SPLEN20187490, SPLEN20193790, SPLEN20201830, TESTI10000190,TESTI20031310, TESTI20035790, TESTI20041630, TESTI20049060,TESTI20050720, TESTI20051200, TESTI20057430, TESTI20057590,TESTI20059080, TESTI20062120, TESTI20067480, TESTI20071630,TESTI20099350, TESTI20105130, TESTI20105910, TESTI20108060,TESTI20125920, TESTI20130530, TESTI20131440, TESTI20134680,TESTI20142540, TESTI20143180, TESTI20150420, TESTI20154370,TESTI20164210, TESTI20166670, TESTI20168880, TESTI20171070,TESTI20182760, TESTI20184750, TESTI20193080, TESTI20194880,TESTI20196970, TESTI20197600, TESTI20201760, TESTI20207170,TESTI20219110, TESTI20228740, TESTI20244430, TESTI20246480,TESTI20251740, TESTI20252690, TESTI20254030, TESTI20257910,TESTI20258720, TESTI20266050, TESTI20271790, TESTI20274960,TESTI20282530, TESTI20286590, THYMU10004280, THYMU20006020,THYMU20013250, THYMU20019260, THYMU20023560, THYMU20028150,THYMU20032820, THYMU20034400, THYMU20055460, THYMU20063650,THYMU20070250, THYMU20071120, THYMU20081110, THYMU20090230,THYMU20095920, THYMU20098350, THYMU20099060, THYMU20120730,THYMU20121040, THYMU20170080, THYMU20185650, THYMU20191970,TKIDN10000620, TKIDN10001920, TRACH20011540, TRACH20091070,TRACH20143710, TRACH20170860, UTERU10001060, UTERU20026620,UTERU20041630, UTERU20086530, UTERU20087070, UTERU20087850,UTERU20099510, UTERU20101150, UTERU20104310, UTERU20127030,UTERU20185220

In particular, hit data of the following 328 clones for Swiss-Prot, orGenBank, UniGene, or nr corresponded to genes or proteins which had beendeposited in the Online Mendelian Inheritance in Man (OMIM), which isthe human gene and disease database, (the OMIM Number is shown in theparenthesis after the Clone Name). ADRGL20020290 (602193), ADRGL20021910(605717), ADRGL20026790 (605046), ADRGL20036840 (142800), ADRGL20059610(230800; 230900; 231000; 231005), ADRGL20066770 (130660), ASTRO20038400(604764), ASTRO20052420 (600888), ASTRO20055570 (176640; 123400; 137440;245300; 600072), ASTRO20075150 (601896), ASTRO20088950 (603202; 223000;223100), BNGH420008150 (600050), BNGH420086030 (118423), BRACE10000510(148021), BRACE20003310 (603899), BRACE20069000 (204200), BRACE20097540(604908), BRACE20194670 (314375), BRACE20196180 (605535), BRACE20204670(176884), BRACE20216950 (158070), BRAMY20003540 (602142), BRAMY20005080(604735), BRAMY20035830 (603524), BRAMY20040580 (604077), BRAMY20043630(602775), BRAMY20044920 (603486), BRAMY20051820 (604567), BRAMY20056620(210210), BRAMY20089770 (602566), BRAMY20111780 (604077), BRAMY20152510(176879), BRAMY20190550 (600051), BRAMY20221600 (605789), BRAMY20227860(605416), BRAMY20274510 (180475), BRAWH20082920 (603246), BRAWH20093040(602989), BRAWH20095900 (602277), BRAWH20190530 (605208), BRAWH20191980(239500), BRCAN10000760 (111000), BRCAN10001050 (603696), BRCAN20005230(603268), BRSSN20066440 (603430), CTONG20004520 (603817), CTONG20029030(602775), CTONG20042640 (103390), CTONG20045500 (106195), CTONG20052780(605612), CTONG20053990 (602187), CTONG20070780 (118990), CTONG20070910(604450), CTONG20072930 (314995), CTONG20083980 (601703), CTONG20084660(600834), CTONG20165750 (182465), CTONG20169040 (148030), CTONG20183430(106410), CTONG20183830 (600382), CTONG20186290 (100660), CTONG20189000(600888), DFNES20016470 (605952), DFNES20025500 (604581), DFNES20046840(602617; 241850), DFNES20055400 (603456), DFNES20080880 (602273),FCBBF10000230 (602327), FCBBF20035490 (602489), FCBBF20066340 (603560),FCBBF30002270 (142708), FCBBF30002280 (176763), FCBBF30019140 (602120),FCBBF30053300 (600299), FCBBF30071500 (125485), FCBBF30072440 (604455),FCBBF30076310 (176892), FCBBF30080730 (600572), FCBBF30100080 (602488),FCBBF30115920 (603577), FCBBF30118670 (603640), FCBBF30129010 (601260),FCBBF30132050 (603018), FCBBF30136230 (189909), FCBBF30153170 (171860;171850), FCBBF30164510 (603006), FCBBF30166220 (182144), FCBBF30171230(162151), FCBBF30175350 (602521), FCBBF30194550 (182900), FCBBF30220050(600380), FCBBF30223210 (300022), FCBBF30263080 (194558), FCBBF30275590(601403), FCBBF50001650 (605268), FEBRA20027070 (314995), FEBRA20045380(602942), FEBRA20046200 (106410), FEBRA20046510 (604077), FEBRA20057010(602187), FEBRA20063720 (603899), FEBRA20078800 (601825; 256000),FEBRA20087550 (600811), FEBRA20088810 (603725), FEBRA20090160 (600137),FEBRA20092760 (602567), FEBRA20170240 (314997), FEBRA20173330 (602990),FEBRA20191720 (603895), HCHON10000150 (300163), HCHON20015050 (151510),HEART20009590 (604581), HEART20022200 (601870), HEART20063100 (602422),HHDPC20081230 (164035), HLUNG20008460 (300108), HLUNG20014590 (604077),HLUNG20032460 (176785), HLUNG20063700 (600210), HLUNG20065990 (186591),HLUNG20069350 (114212), HLUNG20081530 (162230), HLUNG20082350 (604677),HLUNG20083330 (120180), HLUNG20085210 (604464), KIDNE20081170 (604535),KIDNE20084040 (602382), KIDNE20088240 (605084), KIDNE20089870 (602922),KIDNE20133460 (605430), KIDNE20134890 (117143), KIDNE20141700 (312760),KIDNE20142900 (188040), KIDNE20150730 (179715), KIDNE20152440 (602194),KIDNE20160360 (602488), KIDNE20165390 (604649), KIDNE20169180 (191845),KIDNE20173430 (603831), KIDNE20189960 (275360), LIVER20026440 (601270),MESAN20006200 (151740), MESAN20021130 (600050), MESAN20033220 (600466),MESAN20056890 (600813), MESAN20057240 (126380), MESAN20065990 (601959),MESAN20067430 (191010), MESAN20069530 (604362), NESOP20004520 (153432),NT2NE20018890 (606031), NT2NE20026200 (277730), NT2NE20037050 (300028),NT2NE20053950 (604078), NT2NE20061030 (600834), NT2NE20111190 (602619),NT2NE20117580 (601825; 256000), NT2NE20119980 (191161), NT2NE20140130(601281), NT2NE20141040 (602917), NT2RI20093010 (172460), NT2RP70003110(130160; 194050), NT2RP70046410 (601930), NT2RP70075300 (601856),NTONG20032100 (148065; 193900), NTONG20034540 (602658), OCBBF20000740(602059), OCBBF20012520 (602059), OCBBF20111600 (147625), OCBBF20120010(605008), OCBBF20156450 (314997), OCBBF20157970 (604077), OCBBF20191950(192977), PEBLM20001800 (146900), PEBLM20003260 (194558), PLACE60004260(601891), PLACE60012620 (214500), PLACE60054230 (300108), PLACE60054870(160776), PLACE60062660 (606004), PLACE60087680 (146732), PLACE60184870(172425), PROST20015210 (160745), PROST20024250 (604078), PROST20036350(138295), PROST20050390 (601258), PROST20058860 (182282), PROST20063430(603292), PROST20065790 (171840), PROST20084720 (604426), PROST20099090(602714), PROST20120070 (602809), PROST20127450 (602960), PROST20146590(158340; 113720), PROST20152510 (603367), PROST20168600 (604415),PUAEN10000650 (602960), PUAEN20003120 (601573), SKMUS20008730 (602127),SKMUS20017400 (191030), SKMUS20040440 (604163), SKMUS20073590 (605834),SKMUS20079150 (605596), SKNSH20009710 (191030; 164970), SMINT20002320(601644), SMINT20007470 (190370), SMINT20008110 (604384), SMINT20011950(603430), SMINT20016150 (134790), SMINT20026200 (159556), SMINT20030740(604078), SMINT20049920 (600417), SMINT20077960 (137350; 105120),SMINT20083290 (146900), SMINT20086250 (238330), SMINT20089600 (605926),SMINT20091190 (146900), SPLEN20023540 (605577), SPLEN20024190 (601548),SPLEN20042200 (604167), SPLEN20043680 (126340; 234050; 278730),SPLEN20055600 (194541), SPLEN20057830 (179715), SPLEN20059270 (602165),SPLEN20063890 (600245), SPLEN20073500 (603300), SPLEN20080070 (230000),SPLEN20085910 (603424), SPLEN20090880 (142800), SPLEN20098030 (601742),SPLEN20118050 (301870), SPLEN20136730 (605412), SPLEN20138600 (603728),SPLEN20139100 (147120), SPLEN20139360 (117140), SPLEN20180980 (156560),SPLEN20187490 (179838), SPLEN20193790 (147150), SPLEN20201830 (301870),TESTI10000190 (158340; 113720), TESTI20031310 (107280), TESTI20035790(601940), TESTI20049060 (603889), TESTI20050720 (245050), TESTI20051200(602273), TESTI20057430 (194532), TESTI20057590 (601890), TESTI20059080(604038), TESTI20062120 (604212), TESTI20067480 (602277), TESTI20071630(602692), TESTI20099350 (160776), TESTI20105130 (310400), TESTI20105910(601328), TESTI20108060 (600590), TESTI20125920 (601934), TESTI20130530(146680), TESTI20131440 (114850), TESTI20134680 (117143), TESTI20142540(137960), TESTI20143180 (117143), TESTI20150420 (602732), TESTI20154370(600936), TESTI20164210 (602319), TESTI20166670 (142968), TESTI20168880(151410), TESTI20171070 (604064), TESTI20182760 (601328), TESTI20184750(150320), TESTI20193080 (602128), TESTI20194880 (602260), TESTI20196970(601117), TESTI20197600 (604167), TESTI20201760 (602162), TESTI20207170(480100), TESTI20219110 (601890), TESTI20228740 (604077), TESTI20244430(182900), TESTI20246480 (601486), TESTI20251740 (602731), TESTI20252690(601368), TESTI20254030 (602330), TESTI20257910 (142871), TESTI20258720(182900), TESTI20266050 (109092), TESTI20271790 (604678), TESTI20274960(194558), TESTI20282530 (604077), TESTI20286590 (147267), THYMU10004280(602290), THYMU20006020 (601149), THYMU20013250 (601988), THYMU20019260(603899), THYMU20023560 (142765), THYMU20028150 (190197), THYMU20032820(604077), THYMU20034400 (604449), THYMU20055460 (133280), THYMU20063650(180480), THYMU20070250 (277730), THYMU20071120 (603899), THYMU20081110(602567), THYMU20090230 (602324), THYMU20095920 (605349), THYMU20098350(148040; 131760; 131800; 131900), THYMU20099060 (146900), THYMU20120730(100660), THYMU20121040 (130592), THYMU20170080 (604964), THYMU20185650(602121; 124900), THYMU20191970 (604265), TKIDN10000620 (605072),TKIDN10001920 (603899), TRACH20011540 (191155), TRACH20091070 (100660),TRACH20143710 (601905), TRACH20170860 (147170), UTERU10001060 (311040),UTERU20026620 (314997), UTERU20041630 (602277), UTERU20086530 (173310),UTERU20087070 (216950), UTERU20087850 (605248), UTERU20099510 (604077),UTERU20101150 (164012), UTERU20104310 (604414), UTERU20127030 (150325),UTERU20185220 (600014)

The clones predicted to belong to the category of enzyme and/ormetabolism-related protein are the following 219 clones. ADRGL20059610,ASTRO20026320, ASTRO20050810, ASTRO20088950, BNGH420008150,BNGH420035290, BNGH420074600, BRACE20050870, BRACE20097540,BRACE20200770, BRACE20204670, BRACE20215410, BRAMY20003540,BRAMY20005080, BRAMY20027990, BRAMY20028620, BRAMY20044920,BRAMY20055760, BRAMY20056620, BRAMY20072870, BRAMY20093490,BRAMY20096930, BRAMY20118490, BRAMY20125360, BRAMY20143870,BRAMY20152510, BRAMY20231150, BRAMY20244490, BRAMY20251210,BRAWH20021910, BRAWH20082920, BRAWH20093040, BRAWH20094900,BRAWH20183170, BRAWH20188750, BRAWH20190550, BRAWH20191980,BRCAN20005230, BRCOC20003600, CTONG20051100, CTONG20070910,CTONG20076810, CTONG20079590, CTONG20080140, CTONG20085210,CTONG20186290, DFNES20063460, DFNES20080880, FCBBF20023490,FCBBF20066340, FCBBF30004340, FCBBF30019140, FCBBF30022680,FCBBF30029250, FCBBF30072440, FCBBF30076310, FCBBF30085560,FCBBF30091520, FCBBF30107290, FCBBF30125880, FCBBF30132050,FCBBF30143550, FCBBF30153170, FCBBF30166220, FCBBF30171230,FCBBF30175350, FCBBF30236670, FCBBF30260480, FEBRA20038220,FEBRA20040560, FEBRA20078800, FEBRA20090160, FEBRA20172230,FEBRA20173330, HCHON20000870, HCHON20002710, HEART10001490,HEART20022200, HEART20047640, HEART20082570, HLUNG20011260,HLUNG20032460, HLUNG20041540, HLUNG20042730, HLUNG20054790,KIDNE20080690, KIDNE20083620, KIDNE20084040, KIDNE20147170,KIDNE20152440, KIDNE20173150, KIDNE20186170, KIDNE20189960,LIVER20011640, LIVER20026440, LIVER20055270, MESAN20021130,MESAN20033220, MESAN20038520, MESAN20057240, MESAN20058110,MESAN20065990, MESAN20095800, NT2NE20026200, NT2NE20042550,NT2NE20117580, NT2NE20127900, NT2RI20093010, NT2RP70064570,NTONG20034540, NTONG20043080, NTONG20053630, NTONG20053730,NTONG20058010, OCBBF20120010, OCBBF20167290, OCBBF20191950,PANCR10000860, PLACE60052940, PLACE60064180, PLACE60073090,PLACE60095600, PLACE60184410, PLACE60188630, PROST20007600,PROST20033240, PROST20036350, PROST20039300, PROST20050390,PROST20051310, PROST20052850, PROST20065790, PROST20075280,PROST20084720, PROST20099090, PROST20108850, PROST20152510,PUAEN20001520, PUAEN20002470, SKNMC20006350, SKNSH20057920,SMINT20008110, SMINT20049920, SMINT20094680, SPLEN20023540,SPLEN20024930, SPLEN20043680, SPLEN20048800, SPLEN20054500,SPLEN20057900, SPLEN20071820, SPLEN20080070, SPLEN20085910,SPLEN20108000, SPLEN20136730, SPLEN20180980, TESTI20012080,TESTI20030200, TESTI20031310, TESTI20038240, TESTI20050720,TESTI20051200, TESTI20059080, TESTI20062120, TESTI20066330,TESTI20076570, TESTI20103690, TESTI20105130, TESTI20106820,TESTI20108060, TESTI20112860, TESTI20121040, TESTI20130530,TESTI20131440, TESTI20168880, TESTI20170170, TESTI20196690,TESTI20196970, TESTI20199110, TESTI20205250, TESTI20212970,TESTI20222030, TESTI20226520, TESTI20227380, TESTI20244460,TESTI20244730, TESTI20250630, TESTI20260640, TESTI20262940,TESTI20264530, TESTI20285230, THYMU20006020, THYMU20013250,THYMU20034400, THYMU20039320, THYMU20055460, THYMU20055760,THYMU20063650, THYMU20066660, THYMU20070250, THYMU20087270,THYMU20096580, THYMU20100940, THYMU20110720, THYMU20120240,THYMU20120730, THYMU20170230, TRACH20011010, TRACH20021380,TRACH20091070, TRACH20113020, TRACH20143710, TRACH20164100,TRACH20190460, UTERU20087070, UTERU20089620, UTERU20104310,UTERU20185220, UTERU20188670

The clones predicted to belong to the category of cell division and/orcell proliferation-related protein are the following 44 clones.ASTRO20090680, BRACE20079370, BRAMY20234820, BRCAN10001050,BRCAN20005410, CTONG20032930, FCBBF20070950, FCBBF30002270,FCBBF30053300, FCBBF30105860, FCBBF30175350, FCBBF30215240,FCBBF30275590, FEBRA20045380, HLUNG20068120, KIDNE20134890,KIDNE20150730, MESAN20021470, NT2NE20077250, NT2NE20153620,NT2RP70030840, NTONG20053910, OCBBF20111370, OCBBF20174580,PROST20063430, SKNMC10001230, SMINT20028800, SPLEN20023540,SPLEN20057830, SPLEN20139360, TESTI20031410, TESTI20057840,TESTI20065650, TESTI20066650, TESTI20107320, TESTI20108060,TESTI20114480, TESTI20134680, TESTI20143180, TESTI20150920,TESTI20201760, TESTI20278280, TESTI20284260, THYMU20097920

The clones predicted to belong to the category of cytoskeleton-relatedprotein are the following 80 clones. ADRGL20062330, ASTRO20053430,BGGI120000670, BRACE20079370, BRAMY20038980, BRAMY20083330,BRAMY20094890, CTONG20004110, CTONG20032930, CTONG20077760,CTONG20083980, CTONG20169040, CTONG20183430, DFNES20018000,FCBBF30105860, FCBBF30130410, FCBBF30194550, FCBBF30201630,FCBBF30271990, FEBRA20005040, FEBRA20046200, FEBRA20099860,HCHON20015050, HLUNG20081530, KIDNE20081170, NT2RP70001730,NT2RP70003110, NTONG20032100, OCBBF20166890, OCBBF20174890,PLACE60054870, PLACE60055590, PLACE60071800, PLACE60118810,PROST20015210, PROST20097840, PROST20120070, PROST20146590,SKMUS20007260, SKMUS20008730, SKMUS20017400, SKMUS20073590,SMINT20062050, SMINT20074330, SMINT20077960, SPLEN20039180,SPLEN20049840, SPLEN20076470, SPLEN20182990, SPLEN20187490,SPLEN20195710, TESTI10000190, TESTI20041630, TESTI20057880,TESTI20058920, TESTI20060080, TESTI20064530, TESTI20064650,TESTI20065650, TESTI20067440, TESTI20071130, TESTI20099350,TESTI20112540, TESTI20125280, TESTI20136010, TESTI20153310,TESTI20175370, TESTI20222460, TESTI20244430, TESTI20254030,TESTI20258720, THYMU20024500, THYMU20062610, THYMU20098350,TRACH20043360, TRACH20098510, TRACH20149500, UTERU20089390,UTERU20122520, UTERU20168960

The clones predicted to belong to the category of nuclear protein and/orRNA synthesis-related protein are the following 70 clones.ASTRO20026320, BRACE20050870, BRACE20200770, BRAMY20134050,BRAWH20063010, BRAWH20093040, BRAWH20174330, BRAWH20176850,CTONG20042640, FCBBF20023490, FCBBF20035490, FCBBF20070950,FCBBF30002270, FCBBF30048420, FCBBF30080730, FCBBF30115920,FCBBF30236670, FEBRA20035240, FEBRA20092760, FEBRA20173330,HHDPC20081230, HLUNG20011460, HLUNG20068120, KIDNE20089870,KIDNE20150730, MESAN20056890, MESAN20057240, NT2NE20037050,NT2NE20167660, NT2RP70031070, NTONG20053730, PLACE60064180,PLACE60095600, PROST20016760, PROST20051310, PROST20058860,PROST20152510, PUAEN20002470, SKMUS20079150, SKNSH20030640,SPLEN20023850, SPLEN20057830, SPLEN20139360, SPLEN20190430,TESTI20006830, TESTI20030200, TESTI20031410, TESTI20035790,TESTI20062120, TESTI20065650, TESTI20081890, TESTI20150920,TESTI20153310, TESTI20201760, TESTI20212970, TESTI20227380,TESTI20251740, TESTI20256560, TESTI20260640, TESTI20270130,TESTI20284260, TESTI20285230, THYMU20021090, THYMU20049060,THYMU20066660, THYMU20081110, THYMU20090230, THYMU20120240,UTERU10001060, UTERU20104310

The clones predicted to belong to the category of protein synthesisand/or transport-related protein are the following 20 clones.BRAMY20038980, BRAMY20274510, CTONG20008190, CTONG20033610,FCBBF20018680, FEBRA20090220, KIDNE20141700, NT2NE20167660,NTONG20055200, PLACE60012620, PROST20036350, PROST20062820,SKMUS20040440, SMINT20000070, SPLEN20180980, TESTI20055680,TESTI20067440, TESTI20107240, THYMU20096580, THYMU20121040

The clones predicted to belong to the category of cellulardefense-related protein are the following 10 clones. ASTRO20089600,BRAMY20117670, FEBRA20087550, HLUNG20081390, MESAN20057240,NTONG20031580, PROST20007600, SPLEN20023850, SPLEN20043680,TESTI20261680

The clones predicted to belong to the category of development and/ordifferentiation-related protein are the following 19 clones.BRACE20061620, BRACE20200770, BRAMY20013670, CTONG20017490,CTONG20020950, HCHON10000150, MESAN20021470, OCBBF20165910,PROST20155370, PUAEN20002470, TESTI20079220, TESTI20079980,TESTI20166670, TESTI20184760, TESTI20252690, TRACH20040390,UTERU20089620, UTERU20094830, UTERU20169020

The clones predicted to belong to the category of DNA-binding and/orRNA-binding protein are the following 168 clones. ASTRO20038400,BGGI120010750, BNGH420070370, BRACE20003310, BRACE20061620,BRAMY20001510, BRAMY20040580, BRAMY20076100, BRAMY20111780,BRAMY20274510, BRAWH20040680, BRAWH20050740, BRAWH20063010,BRAWH20080580, BRAWH20095900, BRAWH20174330, BRSSN20066440,CTONG20020950, CTONG20044230, CTONG20053990, CTONG20072930,CTONG20074000, CTONG20165750, CTONG20186370, CTONG20186520,DFNES20046840, DFNES20073320, FCBBF20035430, FCBBF20070950,FCBBF30002270, FCBBF30003610, FCBBF30019140, FCBBF30021900,FCBBF30048420, FCBBF30080730, FCBBF30093170, FCBBF30114850,FCBBF30129010, FCBBF30136230, FCBBF30220050, FCBBF30228940,FCBBF30236670, FCBBF30263080, FCBBF30285930, FCBBF50003530,FEBRA20026820, FEBRA20027070, FEBRA20035240, FEBRA20046510,FEBRA20057010, FEBRA20063720, FEBRA20087550, FEBRA20092760,FEBRA20170240, FEBRA20177800, HCHON20002650, HEART20019310,HEART20063100, HHDPC20081230, HLUNG20011460, HLUNG20014590,HLUNG20028110, HLUNG20063700, HLUNG20068120, KIDNE20140870,LIVER20006260, MESAN20016270, MESAN20056890, MESAN20057240,NT2NE20038870, NT2NE20053950, NT2NE20060750, NT2NE20079670,NT2NE20082600, NT2NE20087270, NT2RP70029780, NT2RP70046410,NT2RP70057500, NT2RP70075300, NT2RP70090870, OCBBF20116250,OCBBF20120950, OCBBF20121910, OCBBF20156450, OCBBF20157970,OCBBF20166900, OCBBF20175360, OCBBF20177540, PEBLM10001470,PEBLM20003260, PLACE60066970, PLACE60122970, PLACE60177880,PROST20007170, PROST20024250, PROST20035170, PROST20051310,PROST20058860, PROST20151370, PROST20155370, PUAEN20003120,SMINT20011950, SMINT20030740, SMINT20039050, SMINT20044140,SMINT20086720, SPLEN20042200, SPLEN20043680, SPLEN20055600,SPLEN20059270, SPLEN20063250, SPLEN20139360, SPLEN20190430,TESTI10001570, TESTI20006830, TESTI20030200, TESTI20031410,TESTI20035790, TESTI20057430, TESTI20059810, TESTI20062120,TESTI20067480, TESTI20068790, TESTI20075240, TESTI20079220,TESTI20088840, TESTI20104090, TESTI20134970, TESTI20166670,TESTI20171070, TESTI20173960, TESTI20184760, TESTI20197600,TESTI20201760, TESTI20212970, TESTI20227380, TESTI20228740,TESTI20246480, TESTI20254030, TESTI20254990, TESTI20266050,TESTI20268240, TESTI20270130, TESTI20274960, TESTI20282530,TESTI20284260, TESTI20285230, THYMU10004280, THYMU20019260,THYMU20023560, THYMU20032820, THYMU20049060, THYMU20066660,THYMU20071120, THYMU20077250, THYMU20081110, THYMU20090230,TKIDN10001920, TRACH20108240, UTERU10001060, UTERU20026620,UTERU20041630, UTERU20094830, UTERU20099510, UTERU20101150,UTERU20169020, UTERU20177150, UTERU20188670

The clones predicted to belong to the category of ATP binding and/orGTP-binding protein are the following 93 clones. ASTRO20026320,BNGH420035290, BRACE20050870, BRACE20079370, BRACE20200770,BRAMY20055760, BRAMY20118490, BRAMY20244490, BRAMY20251210,BRAWH20093040, BRAWH20190550, BRCAN10001050, BRCOC20003600,CTONG20008190, CTONG20030280, CTONG20032930, CTONG20176040,CTONG20184830, FCBBF20023490, FCBBF30019140, FCBBF30076310,FCBBF30105860, FCBBF30175350, FCBBF30201630, FCBBF30236670,FEBRA20005040, FEBRA20090160, FEBRA20173330, HCHON20000870,HLUNG20011260, HLUNG20052300, KIDNE20081170, KIDNE20134890,LIVER20030650, LIVER20055270, MESAN20065990, NT2NE20042550,NTONG20043080, NTONG20055200, OCBBF20182060, PLACE60054870,PLACE60064180, PLACE60095600, PLACE60140640, PROST20015210,PROST20033240, PROST20036350, PROST20051310, PROST20052850,PROST20062820, PROST20075280, PROST20120070, PUAEN20002470,SKNSH20052400, SKNSH20057920, SMINT20008110, SPLEN20023850,SPLEN20043680, SPLEN20049840, SPLEN20136730, SPLEN20180980,SPLEN20193790, TESTI20055680, TESTI20058920, TESTI20060080,TESTI20064650, TESTI20071130, TESTI20099350, TESTI20106820,TESTI20112860, TESTI20134680, TESTI20136010, TESTI20143180,TESTI20175370, TESTI20212970, TESTI20222460, TESTI20227380,TESTI20244220, TESTI20244460, TESTI20264530, THYMU20013250,THYMU20039320, THYMU20062610, THYMU20066660, THYMU20087270,THYMU20096580, THYMU20100940, THYMU20176010, TRACH20043360,TRACH20098510, TRACH20113020, UTERU20185220, UTERU20188670

Among the clones other than the ones shown above, BNGH420036410 andFCBBF30257370 are clones which were predicted to highly possibly belongto the category of secretory protein and/or membrane protein based onthe result of domain search by Pfam.

SMINT20044730, TESTI20140970

The two clones shown above are clones which were predicted to highlypossibly belong to the category of glycoprotein-related protein based onthe result of domain search by Pfam. BRACE20055560, CTONG20046690,DFNES20043710, FCBBF30005500, MESAN20030350, MESAN20030370,PLACE60074820, TESTI20058350, TESTI2010E170, TRACH20131230,UTERU20000950

The 11 clones shown above are clones which were predicted to highlypossibly belong to the category of signal transduction-related proteinbased on the result of domain search by Pfam. ASTRO20010290,BRACE20099070, CTONG20007660, DFNES20076340, DFNES20094820,FCBBF30125460, FCBBF30142290, FCBBF30169280, FEBRA20031000,NT2NE20026510, NT2RP70031340, PLACE50001390, SPLEN20135030,TESTI20046890, TESTI20060350, TESTI20166290, TESTI20259110,THYMU20184550

The 18 clones shown above are clones which were predicted to highlypossibly belong to the category of transcription-related protein basedon the result of domain search by Pfam. ADRGL20047770, ADRGL20079060,BRACE20014450, BRACE20051600, BRAWH20185260, CTONG20033750,CTONG20070090, CTONG20190290, FCBBF20020440, FCBBF30005360,FCBBF30173960, FEBRA20031000, KIDNE20087880, LIVER20013890,MESAN20030350, MESAN20030370, OCBBF20113110, PLACE60074820,PLACE60093380, PROST20028970, PROST20102190, SALGL10001070,SPLEN20006950, SPLEN20011350, SPLEN20050090, TESTI20060830,TESTI20066150, TESTI20120900, TESTI20132310, TESTI20148380,TESTI20162980, TESTI20166290, TESTI20205100, THYMU20112590,TRACH20029880

The 35 clones shown above are clones which were predicted to highlypossibly belong to the category of enzyme and/or metabolism-relatedprotein based on the result of domain search by Pfam.

PLACE60054820, TESTI20197030

The two clones shown above are clones which were predicted to highlypossibly belong to the category of cell division and/or cellproliferation-related protein based on the result of domain search byPfam.

ASTRO20006530, OCBBF20016390, TRACH20058000

The three clones shown above are clones which were predicted to highlypossibly belong to the category of cytoskeleton-related protein based onthe result of domain search by Pfam.

BRACE20065470, PLACE60054820

The two clones shown above are clones which were predicted to highlypossibly belong to the category of nuclear protein and/or RNAsynthesis-related protein based on the result of domain search by Pfam.ASTRO20010290, BRACE20099070, BRAWH20014590, CTONG20007660,DFNES20076340, DFNES20094820, FCBBF30125460, FCBBF30142290,FCBBF30169280, FEBRA20031000, MESAN20034440, NT2NE20026510,NT2RP70031340, PLACE50001390, SPLEN20135030, TESTI20046890,TESTI20060350, TESTI20166290, TESTI20259110, THYMU20104480,THYMU20184550

The 21 clones shown above are clones which were predicted to highlypossibly belong to the category of DNA-binding and/or RNA-bindingprotein based on the result of domain search by Pfam.

KIDNE20133880, MESAN20030350, MESAN20030370, TESTI20059480

The four clones shown above are clones which were predicted to highlypossibly belong to the category of ATP-binding and/or GTP-bindingprotein based on the result of domain search by Pfam.

The 205 clones shown below are clones which were unassignable to any ofthe above-mentioned categories, but have been predicted to have somefunctions based on homology search for their full-length nucleotidesequences and motif search in their deduced ORFs. Clone Name, Definitionin the result of homology search or Motif Name in the motif search,demarcated by a double slash mark (//), are shown below.

-   ADRGL20022600//DIAPHANOUS PROTEIN HOMOLOG 1 (P140MDIA).-   ADRGL20023920//ABC1 PROTEIN HOMOLOG PRECURSOR.-   ASTRO20001910//Rattus norvegicus mRNA for annexin V-binding protein    (ABP-10), partial cds.-   ASTRO20009140//PUTATIVE COMPETENCE-DAMAGE PROTEIN.-   ASTRO20046280//PSU1 PROTEIN.-   ASTRO20058960//DNA damage inducible protein homolog—fission yeast    (Schizosaccharomyces pombe)-   BNGH420024870//C2 domain//C2 domain//C2 domain-   BRACE20007330//RING CANAL PROTEIN (KELCH PROTEIN).-   BRACE20052430//Homo sapiens AMSH mRNA, complete cds.-   BRACE20054600//Xenopus laevis mRNA for Kielin, complete cds.-   BRACE20059810//TSC-22/dip/bun family-   BRACE20063540//MEROZOITE SURFACE PROTEIN CMZ-8 (FRAGMENT).-   BRACE20079200//Xenopus laevis mRNA for Kielin, complete cds.-   BRAMY20016780//Proprotein convertase P-domain-   BRAMY20023640//UBX domain-   BRAMY20045420//Domain found in Dishevelled, Egl-10, and Pleckstrin-   BRAMY20056840//UBE-1c2-   BRAMY20063750//Homo sapiens HRIHFB2007 mRNA, partial cds.-   BRAMY20102900//Homo sapiens RU1 (RU1) mRNA, complete cds.-   BRAMY20158550//CALMODULIN.-   BRAMY20223010//Mus musculus leucine-rich glioma-inactivated 1    protein precursor, (Lgi1) mRNA, complete cds.-   BRAMY20238630//TETRATRICOPEPTIDE REPEAT PROTEIN 4.-   BRAMY20245760//Araneus diadematus fibroin-4 mRNA, partial cds.-   BRAWH20047790//HMG (high mobility group) box-   BRSSN20005610//Mus musculus semaphorin cytoplasmic domain-associated    protein 3A (Semcap3) mRNA, complete cds.-   BRSSN20005660//Bacterial type II secretion system protein-   BRSSN20093890//Homo sapiens mRNA for Kelch motif containing protein,    complete cds.-   CTONG20041150//Streptomyces ansochromogenes strain 7100 SanE (sanE)    gene, complete cds.-   CTONG20066110//Homo sapiens DEME-6 mRNA, partial cds.-   CTONG20069420//Ribosomal protein S14p/S29e-   CTONG20071040//BETA CRYSTALLIN B2 (BP).-   CTONG20074170//DENN (AEX-3) domain-   CTONG20083430//Nuclear transition protein 2-   CTONG20170940//MYOTROPHIN (V-1 PROTEIN) (GRANULE CELL    DIFFERENTIATION PROTEIN).-   CTONG20174290//TRICHOHYALIN.-   CTONG20174580//Homo sapiens mRNA for vascular Rab-GAP/TBC-containing    protein complete cds.-   CTONG20180690//Collagen triple helix repeat (20 copies)-   CTONG20186550//cca3 protein—rat-   CTONG20188080//TPR Domain-   FCBBF10004760//Homo sapiens GAP-like protein (N61) mRNA, complete    cds.-   FCBBF20033360//RING CANAL PROTEIN (KELCH PROTEIN).-   FCBBF20041380//SAM domain (Sterile alpha motif)-   FCBBF20043730//UBA domain-   FCBBF20056580//Mus musculus NSD1 protein mRNA, complete cds.-   FCBBF20059660//TPR Domain-   FCBBF30019180//SERINE/THREONINE PROTEIN PHOSPHATASE 2A, 65 KDA    REGULATORY SUBUNIT A, ALPHA ISOFORM (PP2A, SUBUNIT A, PR65-ALPHA    ISOFORM) (PP2A, SUBUNIT A, R1-ALPHA ISOFORM).-   FCBBF30026580//Homo sapiens retinoblastoma-associated protein RAP140    mRNA, complete cds.-   FCBBF30035570//C2 domain-   FCBBF30079770//D-isomer specific 2-hydroxyacid dehydrogenases-   FCBBF30100120//Mus musculus semaphorin cytoplasmic domain-associated    protein 3A (Semcap3) mRNA, complete cds.-   FCBBF30100410//Mus musculus testis-specific Y-encoded-like protein    (Tspyl1) mRNA, complete cds.-   FCBBF30118890//Drosophila melanogaster La related protein (larp)    mRNA, partial cds.-   FCBBF30138000//trg protein—rat-   FCBBF30157270//Rattus norvegicus PAPIN mRNA, complete cds.-   FCBBF30161780//gag gene protein p24 (core nucleocapsid    protein)//Zinc knuckle-   FCBBF30198670//dof protein—fruit fly (Drosophila melanogaster)-   FCBBF30222910//Mus musculus Rap2 interacting protein 8 (RPIP8) mRNA,    complete cds.-   FCBBF30255680//Rattus norvegicus brain specific cortactin-binding    protein CBP90 mRNA, partial cds.-   FCBBF30260210//Drosophila melanogaster KISMET-L long isoform (kis)    mRNA, complete cds.-   FCBBF30282020//cca3 protein—rat-   FCBBF40000610//late gestation lung 2 protein [Rattus norvegicus].-   FEBRA20029620//Leucine Rich Repeat//Leucine Rich Repeat//Leucine    Rich Repeat-   FEBRA20031150//Homo sapiens HSKM-B (HSKM-B) mRNA, complete cds.-   FEBRA20038330//Corticotropin-releasing factor family-   FEBRA20038970//Homo sapiens mRNA for stabilin-1 (stab1 gene).-   FEBRA20088610//CELLULAR RETINALDEHYDE-BINDING PROTEIN (CRALBP).-   FEBRA20150420//HYPOTHETICAL 131.5 KDA PROTEIN CO₂F12.7 IN CHROMOSOME    X.-   FEBRA20175330//D-isomer specific 2-hydroxyacid dehydrogenases-   HEART10001420//Mus musculus skm-BOP1 (Bop) mRNA, complete cds.-   HLUNG20024050//Rubredoxin-   HLUNG20030420//Mus musculus mRNA for MAIL, complete cds.-   HLUNG20030490//Ambystoma tigrinum RPE65 protein mRNA, complete cds.-   HLUNG20033060//Homo sapiens GAP-like protein (N61) mRNA, complete    cds.-   HLUNG20041590//ubiquitous tetratricopeptide containing protein RoXaN    [Homo sapiens].-   HLUNG20045340//MOB2 PROTEIN (MPS1 BINDER 2).-   HLUNG20051330//FHIPEP family-   HLUNG20070410//Dihydropyridine sensitive L-type calcium channel    (Beta subunit)-   HLUNG20072100//Gallus gallus Dach2 protein (Dach2) mRNA, complete    cds.-   HLUNG20083480//Chicken mRNA for TSC-22 variant, complete cds, clone    SLFEST52.-   KIDNE20027980//SAM domain (Sterile alpha motif)-   KIDNE20084730//Homo sapiens FH1/FH2 domain-containing protein FHOS    (FHOS) mRNA, complete cds.-   KIDNE20149780//NG28 [Mus musculus]-   KIDNE20154330//Rattus norvegicus mRNA for multi PDZ domain protein.-   KIDNE20170400//Leucine Rich Repeat//Leucine Rich Repeat//Leucine    Rich Repeat//Protein kinase C terminal domain//Rubredoxin-   KIDNE20189890//Homo sapiens mRNA for KARP-1-binding protein 2    (KAB2), complete cds.-   LIVER20010760//Homo sapiens C-type lectin-like receptor-1 mRNA,    complete cds.-   LIVER20040740//RETINAL-BINDING PROTEIN (RALBP).-   MESAN20009090//Homo sapiens CEGP1 protein (CEGP1), mRNA-   MESAN20026870//PAN domain//TBC domain-   MESAN20090190//CEGP1 protein [Homo sapiens].-   NT2NE20059680//Homo sapiens integrin cytoplasmic domain associated    protein (Icap-1a) mRNA, complete cds.-   NT2NE20077270//Adenovirus EB1 55K protein/large t-antigen-   NT2NE20087850//ANTER-SPECIFIC PROLINE-RICH PROTEIN APG (PROTEIN CEX)    (FRAGMENT).-   NT2NE20095230//Homo sapiens HSKM-B (HSKM-B) mRNA, complete cds.-   NT2NE20108420//KES1 PROTEIN.-   NT2NE20173970//Rattus norvegicus beta-catenin binding protein mRNA,    complete cds.-   NT2NE20177210//Leishmania major partial ppg1 gene for    proteophosphoglycan.-   NT2RP70012830//CALPHOTIN.-   NT2RP70035110//Caenorhabditis elegans UNC-89 (unc-89) gene, complete    cds.-   NTONG20002230//Mus musculus RW1 protein mRNA, complete cds.-   NTONG20005310//Ribosomal protein S9/S16-   NTONG20029850//CALCYPHOSINE (R2D5 ANTIGEN).-   NTONG20035150//RING CANAL PROTEIN (KELCH PROTEIN).-   NTONG20058220//Homo sapiens phosphoprotein pp75 mRNA, partial cds.-   OCBBF20005220//Rattus norvegicus Fos-related antigen mRNA, complete    cds.-   OCBBF20011860//Mus musculus epithelial protein lost in neoplasm-a    (Eplin) mRNA, complete cds.-   OCBBF20016810//enhancer of polycomb [Mus musculus]-   OCBBF20147070//DNA polymerase (viral) C-terminal domain-   OCBBF20160380//liver stage antigen LSA-1—Plasmodium falciparum-   OCBBF20177910//Corticotropin-releasing factor family-   PEBLM20005020//Virion host shutoff protein-   PLACE60055460//Homo sapiens leucine-zipper protein FKSG13 (FKSG13)    mRNA, complete cds.-   PLACE60068710//SUPPRESSOR PROTEIN SRP40.-   PLACE60080360//mucin [Homo sapiens]-   PLACE60082850//Pathogenesis-related protein Bet v I family-   PLACE60098350//Human hepatocellular carcinoma associated protein    (JCL-1) mRNA, complete cds.-   PLACE60105680//Homo sapiens mRNA for TU12B1-TY, complete cds.-   PLACE60119700//Homo sapiens mRNA for ABP32, complete cds.-   PLACE60120280//SER/THR-RICH PROTEIN T10 IN DGCR REGION.-   PLACE60132200//TRICHOHYALIN.-   PLACE60181870//Pentaxin family-   PROST20084470//Plasmodium berghei strain NYU2 merozoite surface    protein-1 mRNA, partial cds.-   PROST20087240//gag gene protein p24 (core nucleocapsid protein)-   PROST20122490//Gallus gallus syndesmos mRNA, complete cds.-   PROST20130320//S-100/ICaBP type calcium binding domain-   PROST20152870//Homo sapiens APC2 gene, exon 14.-   PUAEN10001640//Mus musculus cerebellar postnatal development    protein-1 (Cpd1) mRNA, partial cds.-   PUAEN20000800//Bleomycin resistance protein-   SMINT20012220//Collagen triple helix repeat (20 copies)-   SMINT20035510//Drosophila melanogaster La related protein (larp)    mRNA, partial cds.-   SMINT20036440//Drosophila melanogaster epsin-like protein mRNA,    complete cds.-   SMINT20038660//Homo sapiens HNOEL-iso (HNOEL-iso) mRNA, complete    cds.-   SMINT20043390//Ras association (RalGDS/AF-6) domain-   SMINT20048720//Cytochrome P450//Cytochrome P450-   SMINT20052130//Rattus norvegicus mRNA for gankyrin homologue,    complete cds.-   SMINT20054050//ABC1 PROTEIN HOMOLOG PRECURSOR.-   SPLEN20024770//Rattus norvegicus (rsec6) mRNA, complete cds.-   SPLEN20040780//CORNIFIN B (SMALL PROLINE-RICH PROTEIN 1B) (SPR1B)    (SPR1 B).-   SPLEN20041810//BC-2 protein [Homo sapiens]-   SPLEN20100040//258.1 KDA PROTEIN C210RF5 (KIAA0933).-   SPLEN20104150//Ribosomal protein L36-   SPLEN20116720//Homo sapiens misato mRNA, partial cds.-   SPLEN20176130//Homo sapiens mRNA for ALEX1, complete cds.-   SPLEN20181570//TRICHOHYALIN.-   TESTI20004310//TRICHOHYALIN.-   TESTI20016970//TPR Domain-   TESTI20030440//TRICHOHYALIN.-   TESTI20043180//mouse mRNA for megakaryocyte potentiating factor,    complete cds.-   TESTI20043910//IQ calmodulin-binding motif//IQ calmodulin-binding    motif//IQ calmodulin-binding motif//IQ calmodulin-binding motif//IQ    calmodulin-binding motif-   TESTI20044900//Strongylocentrotus purpuratus radial spokehead mRNA,    complete cds.-   TESTI20046110//Extracellular link domain-   TESTI20047930//Homo sapiens NY-REN-2 antigen mRNA, complete cds.-   TEST120049410//Proprotein convertase P-domain-   TESTI20053950//IQ calmodulin-binding motif-   TESTI20054700//Streptococcus pneumoniae strain g375 surface protein    PspC (pspC) gene, pspC-8.1 allele, complete cds.-   TESTI20055880//Serum amyloid A protein-   TESTI20056030//Homo sapiens 88-kDa Golgi protein (GM88) mRNA,    complete cds.-   TESTI20061090//Keratin, high sulfur B2 protein-   TESTI20064370//TPR Domain//TPR Domain//TPR Domain//TPR    Domain//Synaptobrevin-   TESTI20084250//OXYSTEROL-BINDING PROTEIN.-   TESTI20092170//ENV polyprotein (coat polyprotein)-   TESTI20116050//UBX domain-   TESTI20120500//Kelch motif//Kelch motif-   TESTI20126280//Mus musculus STAP mRNA for sperm tail associated    protein, complete cds.-   TESTI20144390//TESTIS-SPECIFIC PROTEIN PBS13.-   TESTI20165990//Ribosomal protein L36-   TESTI20169500//HYPOTHETICAL 51.9 KDA PROTEIN C27F1.04C IN CHROMOSOME    I.-   TESTI20170280//Flagellar L-ring protein-   TESTI20176450//thioredoxin interacting factor [Mus musculus].-   TESTI20179230//Dihydropyridine sensitive L-type calcium channel    (Beta subunit)-   TESTI20180600//Homo sapiens HOM-TES-85 tumor antigen mRNA, complete    cds.-   TESTI20209050//HYPOTHETICAL 113.1 KDA PROTEIN IN PRE5-FET4    INTERGENIC REGION.-   TESTI20210570//RETINAL-BINDING PROTEIN (RALBP).-   TESTI20215310//Homo sapiens calcyclin binding protein mRNA, complete    cds.-   TESTI20247440//Human BLu protein testis isoform (BLu) mRNA, complete    cds.-   TESTI20249360//Homo sapiens DEME-6 mRNA, partial cds.-   TESTI20250220//TRICHOHYALIN.-   TESTI20251440//Rattus norvegicus (rsec6) mRNA, complete cds.-   TESTI20255460//Mus musculus mRNA for MIWI (piwi), complete cds.-   THYMU20009500//TPR Domain-   THYMU20010180//MOB1 PROTEIN (MPS1 BINDER 1).-   THYMU20013810//Human SEC7 homolog Tic (TIC) mRNA, complete cds.-   THYMU20018250//TPR Domain-   THYMU20026950//Mus musculus ROSA 26 transcription AS ROSA26AS mRNA,    complete cds.-   THYMU20028410//Mus musculus Pax transcription activation domain    interacting protein PTIP mRNA, complete cds.-   THYMU20030460//Homo sapiens tumor endothelial marker 7 precursor    (TEM7) mRNA, complete cds.-   THYMU20031330//Homo sapiens putative nucleotide binding protein    mRNA, complete cds.-   THYMU20052460//PHORBOLIN I (FRAGMENTS).-   THYMU20055450//Zona pellucida-like domain-   THYMU20083830//Homo sapiens angiostatin binding protein 1 mRNA,    complete cds.-   THYMU20139160//Uncharacterized protein family UPF0031-   THYMU20151610//Homo sapiens antigen NY-CO-1 (NY-CO-1) mRNA, complete    cds.-   TRACH20093400//TRICHOHYALIN.-   TRACH20104510//Uncharacterized protein family UPF0005-   TRACH20122980//HYPOTHETICAL PROTEIN MJ0798.-   TRACH20139280//PX domain-   TRACH20164810//D-isomer specific 2-hydroxyacid dehydrogenases-   TRACH20165540//Human alpha-1 type I collagen gene surrounding    osteogenesis imperfecta OI type II deletion.-   UTERU20051790//guanylate kinase-interacting protein 1 Maguin-1,    membrane-associated—rat-   UTERU20083020//Domain of unknown function DUF71-   UTERU20121140//Rhodanese-like domain-   UTERU20128560//26.4 KDA PROTEIN IN RUVC-ASPS INTERGENIC REGION.-   UTERU20132620//AXONEME-ASSOCIATED PROTEIN MST101 (2).-   UTERU20134830//pellino (Drosophila) homolog 2 [Homo sapiens]-   UTERU20181270//Zinc knuckle

With respect to the remaining 613 clones, there are so far noinformation available for estimating their functions. However, there isthe possibility that the functions of these clones will be revealed infuture. Their Clone Names are indicated below. ADRGL20027530,ADRGL20040310, ADRGL20040770, ADRGL20046760, ADRGL20047080,ADRGL20057560, ADRGL20067320, ADRGL20095330, ASTRO20003720,ASTRO20004820, ASTRO20012270, ASTRO20020350, ASTRO20022020,ASTRO20027330, ASTRO20047510, ASTRO20069200, ASTRO20076660,ASTRO20091770, ASTRO20141740, BNGH410000570, BNGH420014060,BNGH420040760, BNGH420042910, BNGH420045380, BNGH420061350,BNGH420062340, BNGH420085100, BRACE20009050, BRACE20017790,BRACE20018810, BRACE20025820, BRACE20038920, BRACE20054480,BRACE20057870, BRACE20059110, BRACE20062580, BRACE20069440,BRACE20098860, BRACE20196960, BRACE20200970, BRACE20205840,BRACE20207420, BRACE20212450, BRACE20216700, BRACE20219360,BRAMY10000980, BRAMY20000210, BRAMY20000250, BRAMY20020440,BRAMY20021580, BRAMY20023390, BRAMY20036530, BRAMY20036810,BRAMY20039290, BRAMY20043520, BRAMY20050640, BRAMY20052440,BRAMY20073080, BRAMY20074110, BRAMY20074860, BRAMY20076130,BRAMY20076530, BRAMY20095080, BRAMY20095570, BRAMY20100680,BRAMY20107980, BRAMY20120170, BRAMY20124970, BRAMY20125170,BRAMY20126910, BRAMY20139750, BRAMY20155500, BRAMY20159250,BRAMY20160020, BRAMY20173480, BRAMY20219620, BRAMY20225250,BRAMY20227230, BRAMY20227960, BRAMY20243120, BRAMY20245350,BRAMY20267780, BRAMY20269040, BRAMY20271140, BRAMY20287400,BRAWH20020600, BRAWH20025490, BRAWH20027250, BRAWH20055240,BRAWH20055780, BRAWH20058120, BRAWH20078080, BRAWH20082550,BRAWH20173790, BRAWH20175230, BRAWH20175340, BRAWH20182670,BRAWH20186010, BRCOC10000400, BRHIP20003590, BRHIP20005060,BRSSN20092440, CTONG10000090, CTONG20000340, CTONG20002790,CTONG20008460, CTONG20015240, CTONG20020660, CTONG20027660,CTONG20031150, CTONG20031890, CTONG20033500, CTONG20035240,CTONG20036800, CTONG20039370, CTONG20050490, CTONG20055670,CTONG20057750, CTONG20057950, CTONG20061290, CTONG20062730,CTONG20065240, CTONG20073990, CTONG20074740, CTONG20076230,CTONG20081840, CTONG20133720, CTONG20165590, CTONG20166580,CTONG20168460, CTONG20169530, CTONG20174440, CTONG20179390,CTONG20179980, CTONG20180620, CTONG20181350, CTONG20184130,CTONG20186140, CTONG20190630, DFNES20032550, DFNES20088810,FCBBF10002200, FCBBF20021110, FCBBF20028980, FCBBF20038230,FCBBF20038950, FCBBF20061310, FCBBF20070800, FCBBF30000010,FCBBF30001020, FCBBF30001150, FCBBF30002330, FCBBF30004730,FCBBF30005180, FCBBF30019240, FCBBF30056980, FCBBF30063990,FCBBF30068210, FCBBF30072480, FCBBF30074530, FCBBF30074620,FCBBF30081000, FCBBF30088700, FCBBF30089380, FCBBF30091010,FCBBF30099490, FCBBF30101240, FCBBF30101300, FCBBF30105080,FCBBF30106950, FCBBF30107330, FCBBF30114180, FCBBF30115230,FCBBF30128420, FCBBF30130580, FCBBF30151190, FCBBF30170710,FCBBF30179180, FCBBF30181730, FCBBF30194370, FCBBF30195700,FCBBF40001920, FCBBF40005000, FCBBF50000410, FEBRA20035200,FEBRA20039070, FEBRA20040260, FEBRA20040290, FEBRA20076200,FEBRA20078180, FEBRA20082660, FEBRA20083410, FEBRA20086600,FEBRA20091620, FEBRA20093270, FEBRA20093280, FEBRA20095410,FEBRA20098040, FEBRA20101410, FEBRA20108020, FEBRA20108580,FEBRA20121200, FEBRA20163980, FEBRA20175020, FEBRA20180510,FEBRA20187460, HHDPC20082970, HLUNG20009260, HLUNG20009550,HLUNG20010130, HLUNG20011440, HLUNG20012140, HLUNG20020500,HLUNG20021450, HLUNG20023030, HLUNG20025620, HLUNG20029420,HLUNG20030610, HLUNG20031620, HLUNG20033310, HLUNG20037140,HLUNG20037780, HLUNG20038330, HLUNG20047070, HLUNG20055240,HLUNG20056560, HLUNG20057380, HLUNG20059240, HLUNG20065700,HLUNG20067810, HLUNG20072190, HLUNG20072450, HLUNG20079310,HLUNG20083840, HLUNG20083960, HLUNG20093030, HLUNG20094130,KIDNE20011600, KIDNE20024380, KIDNE20086970, KIDNE20091090,KIDNE20094260, KIDNE20095530, KIDNE20137310, KIDNE20138450,KIDNE20141120, KIDNE20142680, KIDNE20154830, KIDNE20155980,KIDNE20157100, KIDNE20176030, KIDNE20181670, KIDNE20191870,LIVER20007690, LIVER20032340, MESAN20008940, MESAN20021860,MESAN20029780, MESAN20030390, MESAN20041380, MESAN20045750,MESAN20060220, MESAN20085360, MESAN20089260, MESAN20094180,NESOP20005040, NT2NE20028700, NT2NE20033150, NT2NE20045190,NT2NE20047870, NT2NE20062880, NT2NE20066590, NT2NE20070520,NT2NE20073650, NT2NE20077860, NT2NE20086070, NT2NE20088030,NT2NE20104000, NT2NE20107810, NT2NE20112210, NT2NE20114850,NT2NE20123610, NT2NE20124570, NT2NE20126030, NT2NE20140280,NT2NE20148690, NT2NE20149500, NT2NE20150610, NT2NE20157120,NT2NE20165190, NT2NE20181760, NT2NE20184720, NT2RP70022820,NT2RP70049610, NT2RP70056290, NT2RP70074800, NT2RP70080150,NT2RP70084540, NTONG20017620, NTONG20049180, OCBBF20001780,OCBBF20009820, OCBBF20109450, OCBBF20112320, OCBBF20115360,OCBBF20117220, OCBBF20119810, OCBBF20142290, OCBBF20152330,OCBBF20188280, PLACE60001910, PLACE60011180, PLACE60017120,PLACE60055350, PLACE60062870, PLACE60063940, PLACE60069880,PLACE60072390, PLACE60072420, PLACE60077870, PLACE60081260,PLACE60088240, PLACE60092280, PLACE60092370, PLACE60095240,PLACE60109910, PLACE60132320, PLACE60132880, PLACE60155910,PLACE60157310, PLACE60162100, PLACE60175640, PLACE60177910,PROST10001360, PROST10002150, PROST20011800, PROST20014140,PROST20014650, PROST20015400, PROST20022120, PROST20036280,PROST20041460, PROST20042700, PROST20047440, PROST20048170,PROST20052720, PROST20054660, PROST20060200, PROST20078710,PROST20093470, PROST20094000, PROST20097310, PROST20097360,PROST20102500, PROST20103820, PROST20121570, PROST20124000,PROST20125420, PROST20138730, PROST20156360, PROST20159320,SKMUS20026340, SKMUS20064810, SKNSH10001010, SKNSH20007160,SKNSH20040390, SKNSH20068220, SMINT20011830, SMINT20013970,SMINT20014610, SMINT20017310, SMINT20021260, SNINT20023110,SMINT20031280, SMINT20045830, SMINT20045890, SMINT20047290,SMINT20056240, SMINT20067080, SMINT20070620, SMINT20077920,SMINT20084910, SMINT20085310, SMINT20085450, SMINT20089210,SMINT20092120, SMINT20093630, SMINT20094150, SPLEN20005160,SPLEN20005370, SPLEN20012450, SPLEN20015030, SPLEN20016500,SPLEN20019120, SPLEN20020530, SPLEN20023430, SPLEN20024510,SPLEN20029170, SPLEN20036780, SPLEN20043430, SPLEN20043460,SPLEN20045550, SPLEN20051420, SPLEN20062830, SPLEN20067010,SPLEN20076190, SPLEN20081640, SPLEN20087370, SPLEN20087860,SPLEN20108460, SPLEN20110210, SPLEN20111450, SPLEN20114190,SPLEN20117580, SPLEN20126110, SPLEN20137530, SPLEN20192570,SPLEN20193750, SPLEN20197090, SPLEN20197740, SPLEN20199850,SPLEN20200076, SPLEN20200340, SPLEN20203590, SPLEN20205120,TESOP10001600, TESTI10000850, TESTI20005980, TESTI20012360,TESTI20019590, TESTI20028020, TESTI20030610, TESTI20034750,TESTI20035330, TESTI20040850, TESTI20045740, TESTI20049990,TESTI20050170, TESTI20052670, TESTI20053800, TESTI20059330,TESTI20059370, TESTI20059790, TESTI20060150, TESTI20060450,TESTI20062180, TESTI20062580, TESTI20064990, TESTI20066170,TESTI20066280, TESTI20066590, TESTI20067350, TESTI20068940,TESTI20076920, TESTI20079060, TESTI20080460, TESTI20083890,TESTI20085670, TESTI20089290, TESTI20090180, TESTI20090970,TESTI20091360, TESTI20093900, TESTI20094620, TESTI20097270,TESTI20107340, TESTI20113150, TESTI20117500, TESTI201184S0,TESTI20122440, TESTI20124440, TESTI20125440, TESTI20132680,TESTI20134010, TESTI20134270, TESTI20142480, TESTI20151050,TESTI20152490, TESTI20159380, TESTI20161010, TESTI20165680,TESTI20167580, TESTI20170690, TESTI20170890, TESTI20173110,TESTI20179510, TESTI20182210, TESTI20184280, TESTI20184820,TESTI20192570, TESTI20193520, TESTI20197290, TESTI20198600,TESTI20199980, TESTI20200120, TESTI20200840, TESTI20205150,TESTI20211380, TESTI20219390, TESTI20221790, TESTI20223380,TESTI20248850, TESTI20254090, TESTI20254480, TESTI20259200,TESTI20260140, TESTI20265150, TESTI20265340, TESTI20265890,TESTI20269250, TESTI20269360, TESTI20272380, TESTI20277300,TESTI20287760, THYMU20007750, THYMU20008000, THYMU20009460,THYMU20009710, THYMU20010710, THYMU20012560, THYMU20014430,THYMU20018390, THYMU20019000, THYMU20020370, THYMU20021540,THYMU20029830, THYMU20036500, THYMU20043440, THYMU20043560,THYMU20044100, THYMU20044520, THYMU20051340, THYMU20058550,THYMU20060480, THYMU20062520, THYMU20064680, THYMU20069130,THYMU20069460, THYMU20069650, THYMU20071460, THYMU20072580,THYMU20073070, THYMU20073080, THYMU20078020, THYMU20080490,THYMU20083500, THYMU20084520, THYMU20086430, THYMU20089170,THYMU20089900, THYMU20091040, THYMU20112570, THYMU20115730,THYMU20117850, THYMU20128910, THYMU20129020, THYMU20130470,THYMU20134260, THYMU20140510, THYMU20148010, THYMU20149230,THYMU20157620, THYMU20174490, THYMU20174790, THYMU20175260,THYMU20177070, THYMU20181890, THYMU20187210, TKIDN10001710,TRACH20012490, TRACH20021000, TRACH20025370, TRACH20026640,TRACH20041090, TRACH20044990, TRACH20049500, TRACH20051590,TRACH20057200, TRACH20080810, TRACH20093480, TRACH20101590,TRACH20123870, TRACH20124970, TRACH20125620, TRACH20129180,TRACH20140180, TRACH20158240, TRACH20160800, TRACH20174980,TRACH20182780, TRACH20185120, UTERU10001870, UTERU20000230,UTERU20011760, UTERU20013890, UTERU20027360, UTERU20029930,UTERU20031350, UTERU20040370, UTERU20040390, UTERU20040730,UTERU20041970, UTERU20065470, UTERU20079240, UTERU20090940,UTERU20091470, UTERU20102260, UTERU20103040, UTERU20106510,UTERU20140010, UTERU20167570, UTERU20173030, UTERU20176230

EXAMPLE 7 Expression Frequency Analysis In Silico

The cDNA libraries derived from various tissues and cells as indicatedin Example 1 were prepared, and cDNA clones were selected from eachlibrary at random. The 5′-end sequences were determined and the databasewas constructed based on the data. The database was constructed based onthe nucleotide sequences of 770,546 clones, and thus the population ofthe database is large enough for the analysis.

Then, clones having a homologous sequence are categorized into a singlecluster (clustering) by searching the nucleotide sequences of respectiveclones in this database with the program of nucleotide sequence homologysearch; the number of clones belonging to each cluster was determinedand normalized for every library; thus, the ratio of a certain gene ineach cDNA library was determined. This analysis gave the information ofthe expression frequency of genes in tissues and cells which weresources of the cDNA libraries.

Then, in order to analyze the expression of a gene containing thenucleotide sequence of the cDNA of the present invention in tissues andcells, the library derived from a tissue or a cell used in thelarge-scale cDNA analysis was subjected to the comparison of theexpression levels between tissues or cells. Namely, the expressionfrequency was analyzed by comparing the previously normalized valuesbetween tissues and/or cells for which the nucleotide sequences of 600or more cDNA clones had been analyzed. By this analysis, some of thegenes were revealed to be involved in the pathology and functionsindicated below. Each value in Tables 3 to 39 shown below represents arelative expression frequency; the higher the value, the higher theexpression level.

Osteoporosis-Related Genes

Osteoporosis is a pathology in which bones are easily broken owing tooverall decrease in components of bone. The onset involves the balancebetween the functions of osteoblast producing bone and osteoclastabsorbing bone, namely bone metabolism. Thus, the genes involved in theincrease of osteoclasts differentiating from precursor cells ofmonocyte/macrophage line (Molecular Medicine 38. 642-648. (2001)) aregenes involved in osteoporosis relevant to bone metabolism.

A nucleotide sequence information-based analysis was carried out toidentify the genes whose expression frequencies are higher or lower inCD34+ cell (cell expressing a glycoprotein CD34) treated with theosteoclast differentiation factor (Molecular Medicine 38. 642-648.(2001)) than in the untreated CD34+ cell, which is the precursor cell ofmonocyte/macrophage line. The result of comparative analysis for thefrequency between the two cDNA libraries prepared from the RNA of CD34+cells (CD34C) and from the RNA of CD34+ cells treated with theosteoclast differentiation factor (D30ST, D60ST or D90ST) showed thatthe genes whose expression levels were different between the two werethe following clones (Table 3). ASTRO20010290, BRAMY20036530,BRAMY20043630, BRAMY20089770, BRAMY20190550, CD34C20001750,FCBBF20066340, FEBRA20040290, HLUNG20015180, HLUNG20041590,HLUNG20052300, KIDNE20084040, MESAN20021860, MESAN20027240,NTONG20055200, PROST20016760, PUAEN10001640, SMINT20006020,SMINT20028840, SMINT20035050, SPLEN20181570, TESTI20064530,TESTI20210030, THYMU20029830, THYMU20139160, TRACH20051590

These genes are involved in osteoporosis.

Genes Involved in Neural Cell Differentiation

Genes involved in neural cell differentiation are useful for treatingneurological diseases. Genes with varying expression levels in responseto induction of cellular differentiation in neural cells are thought tobe involved in neurological diseases.

A survey was performed for genes whose expression levels are varied inresponse to induction of differentiation (stimulation by retinoic acid(RA) or growth inhibitor treatment after RA stimulation) in culturedcells of a neural strain, NT2. The result of comparative analysis ofcDNA libraries derived from undifferentiated NT2 cells (NT2RM) and thecells subjected to the differentiation treatment (NT2RP, NT2RI or NT2NE)showed that the genes whose expression levels were different between thetwo were the following clones (Table 4). ADRGL20023920, ASTRO20009140,BNGH420077980, BNGH420086030, BRACE20062580, BRACE20079370,BRACE20215410, BRAMY20003540, BRAMY20043630, BRAMY20076130,BRAMY20095080, BRAMY20227860, BRAWH20082550, BRHIP10001040,BRSSN20005610, CTONG20027660, CTONG20044230, CTONG20066110,CTONG20079590, CTONG20084660, CTONG20133720, CTONG20165750,CTONG20188080, FCBBF20023490, FCBBF20033360, FCBBF20059660,FCBBF20070950, FCBBF30004340, FCBBF30095410, FCBBF30125460,FCBBF30179180, FCBBF30236670, FCBBF30257370, FCBBF50000610,FCBBF50001650, FEBRA20038330, FEBRA20039260, FEBRA20063720,FEBRA20090220, FEBRA20150420, HEART10001490, HLUNG20032460,HLUNG20041590, KIDNE20089870, MESAN20016270, MESAN20021860,MESAN20060430, MESAN20067430, NT2NE20018740, NT2NE20018890,NT2NE20021860, NT2NE20026200, NT2NE20026510, NT2NE20028700,NT2NE20033150, NT2NE20037050, NT2NE20038870, NT2NE20039210,NT2NE20042550, NT2NE20045190, NT2NE20047870, NT2NE20053230,NT2NE20053950, NT2NE20059210, NT2NE20059680, NT2NE20060750,NT2NE20061030, NT2NE20062880, NT2NE20064780, NT2NE20066590,NT2NE20069580, NT2NE20070520, NT2NE20073650, NT2NE20077250,NT2NE20077270, NT2NE20077860, NT2NE20079670, NT2NE20080770,NT2NE20082130, NT2NE20082600, NT2NE20086070, NT2NE20087270,NT2NE20087850, NT2NE20088030, NT2NE20092950, NT2NE20095230,NT2NE20104000, NT2NE20107810, NT2NE20108420, NT2NE20111190,NT2NE20112210, NT2NE20114850, NT2NE20117580, NT2NE20119980,NT2NE20123610, NT2NE20124570, NT2NE20126030, NT2NE20127900,NT2NE20140130, NT2NE20140280, NT2NE20141040, NT2NE20145250,NT2NE20146510, NT2NE20148690, NT2NE20149500, NT2NE20150610,NT2NE20152620, NT2NE20153620, NT2NE20155650, NT2NE20157120,NT2NE20165190, NT2NE20167660, NT2NE20173970, NT2NE20177210,NT2NE20181760, NT2NE20181800, NT2NE20184720, NT2RI20016240,NT2RI20021200, NT2RI20033920, NT2RI20093010, NT2RP70001120,NT2RP70001730, NT2RP70003110, NT2RP70012830, NT2RP70022820,NT2RP70027790, NT2RP70029780, NT2RP70030840, NT2RP70031070,NT2RP70031340, NT2RP70031480, NT2RP70035110, NT2RP70046410,NT2RP70049610, NT2RP70056290, NT2RP70056690, NT2RP70057500,NT2RP70064570, NT2RP70074800, NT2RP70075300, NT2RP70075800,NT2RP70080150, NT2RP70084540, NT2RP70087140, NT2RP70090870,OCBBF20001780, OCBBF20009820, OCBBF20142290, OCBBF20155030,OCBBF20175360, OCBBF20177540, OCBBF20177910, PLACE60054820,PLACE60061370, PLACE60073090, PLACE60162100, PROST20011800,PROST20045700, PROST20078710, PROST20094000, PUAEN10000650,PUAEN10001640, SKNMC20006350, SMINT20016150, SMINT20030740,SMINT20035510, SMINT20039050, SMINT20047290, SPLEN20063250,SPLEN20117580, SPLEN20125230, TESTI20030610, TESTI20043910,TESTI20066280, TESTI20067480, TESTI20105130, TESTI20106170,TESTI20143180, TESTI20221790, TESTI20254090, TESTI20274960,THYMU10004280, THYMU20007020, THYMU20104480, THYMU20139160,TRACH20026640, UTERU10001060, UTERU20026620, UTERU20079240,UTERU20083020, UTERU20102260, UTERU20132620

These genes are neurological disease-related genes.

Cancer-Related Genes

It has been assumed that, distinct from normal tissues, cancer tissuesexpress a distinct set of genes, and thus the expression can contributeto the carcinogenesis in tissues and cells. Thus, the genes whoseexpression patterns in cancer tissues are different from those in normaltissues are cancer-related genes. Search was carried out for the geneswhose expression levels in cancer tissues were different from those innormal tissues.

The result of comparative analysis of cDNA libraries derived from breasttumor (TBAES) and normal breast (BEAST) showed that the genes whoseexpression levels were different between the two were the followingclones (Table 5).

CTONG20070780, CTONG20084660, HLUNG20045340, TESTI20047370

The result of comparative analysis of cDNA libraries derived cervicaltumor (TCERX) and normal cervical duct (CERVX) showed that the geneswhose expression levels were different between the two were thefollowing clones (Table 6).

SMINT20030740

The result of comparative analysis of cDNA libraries derived from colontumor (TCOLN) and normal colon (COLON) showed that the genes whoseexpression levels were different between the two were the followingclones (Table 7).

UTERU2004037

The result of comparative analysis of cDNA libraries derived fromesophageal tumor (TESOP) and normal esophagus (NESOP) showed that thegenes whose expression levels were different between the two were thefollowing clones (Table 8). HLUNG20015180, NESOP20004520, NESOP20005040,TESOP10000350, TESOP10001600, THYMU20071120

The result of comparative analysis of cDNA libraries derived from kidneytumor (TKIDN) and normal kidney (KIDNE) showed that the genes whoseexpression levels were different between the two were the followingclones (Table 9). ASTRO20009140, ASTRO20027330, ASTRO20055930,BGGI120010750, BNGH420074600, BRACE20050870, BRACE20054480,BRACE20062580, BRACE20219360, BRAMY20003540, BRAMY20003880,BRAMY20043630, BRAMY20055760, BRAMY20125360, BRAMY20190550,BRAMY20204270, BRAMY20227860, BRAWH20014590, BRAWH20093070,BRHIP10001040, CTONG20033750, CTONG20039370, CTONG20045500,CTONG20079590, FCBBF20023490, FCBBF30004340, FCBBF30106950,FCBBF30115230, FCBBF30169280, FCBBF30225930, FCBBF30282020,FEBRA20038330, FEBRA20039260, FEBRA20040290, FEBRA20082660,FEBRA20121200, FEBRA20170240, HEART10001490, HLUNG20041590,HLUNG20068120, HLUNG20072450, HLUNG20083480, HLUNG20083960,KIDNE20011600, KIDNE20016360, KIDNE20024380, KIDNE20027980,KIDNE20080690, KIDNE20081170, KIDNE20083150, KIDNE20083620,KIDNE20084030, KIDNE20084040, KIDNE20084730, KIDNE20084800,KIDNE20086490, KIDNE20086660, KIDNE20086970, KIDNE20087880,KIDNE20088240, KIDNE20089870, KIDNE20091090, KIDNE20094260,KIDNE20094670, KIDNE20095530, KIDNE20133460, KIDNE20133880,KIDNE20134130, KIDNE20134890, KIDNE20137310, KIDNE20138450,KIDNE20140870, KIDNE20141120, KIDNE20141700, KIDNE20142680,KIDNE20142680, KIDNE20142900, KIDNE20143200, KIDNE20147170,KIDNE20148080, KIDNE20149780, KIDNE20150730, KIDNE20152440,KIDNE20154330, KIDNE20154830, KIDNE20155980, KIDNE20157100,KIDNE20160360, KIDNE20160960, KIDNE20163710, KIDNE20165390,KIDNE20169180, KIDNE20170400, KIDNE20173150, KIDNE20173430,KIDNE20176030, KIDNE20181670, KIDNE20182540, KIDNE20186170,KIDNE20188630, KIDNE20189890, KIDNE20189960, KIDNE20191870,MESAN20038520, MESAN20041380, OCBBF20016390, OCBBF20142290,OCBBF20174890, PLACE60061370, PLACE60073090, PLACE60181870,PROST20016760, PUAEN10000650, SMINT20039050, SMINT20089210,SPLEN20017610, SPLEN20024930, SPLEN20057830, SPLEN20063250,SPLEN20126110, SPLEN20135030, SPLEN20136700, TESTI20070740,TESTI20262150, THYMU20009500, THYMU20019260, THYMU20157620,TKIDN10000620, TKIDN10001710, TKIDN10001920, TRACH20011010,UMVEN10001380

The result of comparative analysis of cDNA libraries derived from livertumor (TLIVE) and normal liver (LIVER) showed that the genes whoseexpression levels were different between the two were the followingclones (Table 10). CTONG20069320, FCBBF30236670, FEBRA20038220,FEBRA20039260, KIDNE20087880, LIVER20006260, LIVER20007690,LIVER20007750, LIVER20010510, LIVER20010760, LIVER20010990,LIVER20011640, LIVER20013890, LIVER20026440, LIVER20030650,LIVER20032340, LIVER20038000, LIVER20040740, LIVER20055270,MESAN20027240, NT2RI20021200, SKMUS20006790, TESTI20035330,THYMU10004280, THYMU20029830

The result of comparative analysis of cDNA libraries derived from lungtumor (TLUNG) and normal lung (HLUNG) showed that the genes whoseexpression levels were different between the two were the followingclones (Table 11). HLUNG20052300, SMINT20035050, HLUNG20041590,PROST20016760, BRAMY20043630, HLUNG20015180, THYMU20139160,HLUNG20020850, HLUNG20032460, BRAMY20204270, BRAMY20001510,BRAMY20227860, CTONG20029030, CTONG20168460, CTONG20186290,FEBRA20039260, FEBRA20078800, FEBRA20163980, HCHON20000870,HLUNG20008460, HLUNG20009260, HLUNG20009550, HLUNG20010130,HLUNG20011260, HLUNG20011440, HLUNG20011460, HLUNG20012140,HLUNG20014590, HLUNG20015070, HLUNG20020500, HLUNG20021450,HLUNG20023030, HLUNG20024050, HLUNG20025620, HLUNG20028110,HLUNG20029420, HLUNG20029490, HLUNG20030420, HLUNG20030490,HLUNG20030610, HLUNG20031620, HLUNG20033060, HLUNG20033310,HLUNG20033350, HLUNG20034970, HLUNG20037140, HLUNG20037160,HLUNG20037780, HLUNG20038330, HLUNG20041540, HLUNG20042730,HLUNG20045340, HLUNG20047070, HLUNG20050760, HLUNG20051330,HLUNG20054790, HLUNG20055240, HLUNG20056560, HLUNG20057380,HLUNG20059240, HLUNG20060670, HLUNG20063700, HLUNG20065700,HLUNG20065990, HLUNG20067810, HLUNG20068120, HLUNG20069350,HLUNG20070410, HLUNG20072100, HLUNG20072190, HLUNG20072450,HLUNG20074330, HLUNG20079310, HLUNG20081390, HLUNG20081530,HLUNG20082350, HLUNG20083330, HLUNG20083480, HLUNG20083840,HLUNG20083960, HLUNG20084790, HLUNG20085210, HLUNG20088750,HLUNG20092530, HLUNG20093030, HLUNG20094130, KIDNE20142900,PROST20052850, SKNMC20006350, SPLEN20012450, TESTI20057590,TESTI20061200, TESTI20067480, TESTI20116050, THYMU10004280,THYMU20010180, TRACH20011010, UTERU20016580, UTERU20127030

The result of comparative analysis of cDNA libraries derived from ovarytumor (TOVER) and normal ovary (NOVER) showed the genes whose expressionlevels were different between the two were the following clones (Table12).

KIDNE20089870, NT2RP70075300, TESTI20132310

The result of comparative analysis of cDNA libraries derived fromstomach tumor (TSTOM) and normal stomach (STOMA) showed that the geneswhose expression levels were different between the two were thefollowing clones (Table 13). BNGH420087430, BRAMY20227860,BRAWH20027250, CTONG20174440, FEBRA20090220, PUAEN10000650,SMINT20023110, SMINT20030740, SMINT20045890, SPLEN20048800,SPLEN20139360, TESTI20063410, TESTI20150920, TRACH20026640,UTERU20041970

The result of comparative analysis of cDNA libraries derived fromuterine tumor (TUTER) and normal uterus (UTERU) showed that the geneswhose expression levels were different between the two were thefollowing clones (Table 14). ADRGL20020290, BRACE20038920,BRAMY20091230, BRAMY20093490, BRAMY20227860, BRHIP20005060,CTONG20069320, CTONG20083430, FCBBF30005360, FCBBF30257370,FEBRA20038330, FEBRA20039260, FEBRA20040260, FEBRA20078180,FEBRA20087550, HLUNG20015070, HLUNG20015180, MESAN20007110,MESAN20067430, MESAN20095800, NT2RP70057500, SKMUS20008730,SKNMC20006350, SMINT20035050, SMINT20045890, SPLEN20073880,SPLEN20076470, SPLEN20118050, TESTI20030610, TESTI20035330,TESTI20057590, TESTI20059080, TESTI20105130, THYMU10004280,THYMU20139160, UTERU10001060, UTERU10001870, UTERU20000230,UTERU20000950, UTERU20011760, UTERU20013890, UTERU20016580,UTERU20026620, UTERU20027360, UTERU20029930, UTERU20031350,UTERU20035770, UTERU20040150, UTERU20040370, UTERU20040390,UTERU20040730, UTERU20041630, UTERU20041970, UTERU20045200,UTERU20051790, UTERU20064120, UTERU20065470, UTERU20079240,UTERU20083020, UTERU20086530, UTERU20087070, UTERU20087850,UTERU20089300, UTERU20089390, UTERU20089620, UTERU20090940,UTERU20091470, UTERU20094830, UTERU20095100, UTERU20099040,UTERU20099510, UTERU20101150, UTERU20102260, UTERU20103040,UTERU20103200, UTERU20104310, UTERU20106510, UTERU20121140,UTERU20122520, UTERU20125810, UTERU20127030, UTERU20127150,UTERU20128560, UTERU20132620, UTERU20134830, UTERU20139760,UTERU20140010, UTERU20167570, UTERU20168960, UTERU20169020,UTERU20173030, UTERU20176230, UTERU20177150, UTERU20181270,UTERU20185220, UTERU20188670, UTERU20188840

The result of comparative analysis of cDNA libraries derived from tonguecancer (CTONG) and normal tongue (NTONG) showed that the genes whoseexpression levels were different between the two were the followingclones (Table 15). ADRGL20023920, BRACE20038920, BRACE20050870,BRACE20061620, BRAMY20036530, BRAMY20076130, BRAMY20204270,BRAMY20267780, BRCAN10001680, CTONG10000090, CTONG20000340,CTONG20002790, CTONG20004110, CTONG20004520, CTONG20007660,CTONG20008190, CTONG20008460, CTONG20015240, CTONG20017490,CTONG20020660, CTONG20020950, CTONG20027660, CTONG20029030,CTONG20030280, CTONG20031150, CTONG20031890, CTONG20032930,CTONG20033500, CTONG20033610, CTONG20033750, CTONG20035240,CTONG20036800, CTONG20036990, CTONG20039370, CTONG20041150,CTONG20041260, CTONG20042640, CTONG20044230, CTONG20044870,CTONG20045500, CTONG20046690, CTONG20049480, CTONG20050490,CTONG20051100, CTONG20051450, CTONG20052780, CTONG20053990,CTONG20055670, CTONG20055850, CTONG20056150, CTONG20057750,CTONG20057950, CTONG20059130, CTONG20060040, CTONG20061290,CTONG20062730, CTONG20063770, CTONG20063930, CTONG20065240,CTONG20065680, CTONG20066110, CTONG20068360, CTONG20069320,CTONG20069420, CTONG20070090, CTONG20070720, CTONG20070780,CTONG20070910, CTONG20071040, CTONG20071680, CTONG20072930,CTONG20073990, CTONG20074000, CTONG20074170, CTONG20074740,CTONG20076230, CTONG20076810, CTONG20077760, CTONG20078340,CTONG20079590, CTONG20080140, CTONG20081840, CTONG20083430,CTONG20083980, CTONG20084020, CTONG20084660, CTONG20085210,CTONG20133720, CTONG20165590, CTONG20165750, CTONG20166580,CTONG20167750, CTONG20168240, CTONG20168460, CTONG20169040,CTONG20169530, CTONG20170940, CTONG20174290, CTONG20174580,CTONG20176040, CTONG20179390, CTONG20179890, CTONG20179980,CTONG20180620, CTONG20180690, CTONG20181350, CTONG20183430,CTONG20183830, CTONG20184130, CTONG20184830, CTONG20186140,CTONG20186290, CTONG20186370, CTONG20186520, CTONG20186550,CTONG20188080, CTONG20189000, CTONG20190290, CTONG20190630,FCBBF20070950, FCBBF30001100, FCBBF30175350, FCBBF40005000,FEBRA20027070, FEBRA20038330, FEBRA20039260, FEBRA20040290,FEBRA20046200, FEBRA20063720, FEBRA20078800, FEBRA20090220,HCHON20000870, HLUNG20068120, MESAN20008150, MESAN20027900,NT2NE20153620, NT2RP70001730, NT2RP70012830, NT2R270027790,NT2RP70057500, NT2RP70064570, NT2RP70090870, NTONG20002230,NTONG20005310, NTONG20017620, NTONG20029850, NTONG20031580,NTONG20032100, NTONG20034540, NTONG20035150, NTONG20043080,NTONG20048440, NTONG20049180, NTONG20053630, NTONG20053730,NTONG20053910, NTONG20055200, NTONG20058010, NTONG20058220,OCBBF20110730, OCBBF20177540, OCBBF20177910, PROST20016760,PROST20042700, PROST20050390, PROST20063430, PROST20130320,PUAEN10000650, PUAEN10001640, PUAEN20003120, SKMUS20006790,SKNMC20006350, SKNSH20007160, SMINT20030740, SMINT20035510,SMINT20089210, SPLEN20024930, SPLEN20040780, SPLEN20063250,SPLEN20181570, SPLEN20187490, TESTI20047370, TESTI20057880,TESTI20064530, TESTI20079980, TESTI20105130, TESTI20118460,TESTI20121040, TESTI20197290, THYMU10004280, THYMU20030460,THYMU20055460, THYMU20089900, THYMU20121040, THYMU20139160,THYMU20145990, TRACH20011010, TRACH20090060, UTERU20000230,UTERU20000950, UTERU20016580, UTERU20045200, UTERU20083020

These genes are involved in cancers.

Further, there is a method to search for genes involved in developmentand differentiation: the expression frequency analysis in which theexpression levels of genes are compared between developing ordifferentiating tissues and/or cells and adult tissues and/or cells. Thegenes involved in tissue development and/or differentiation are genesparticipating in tissue construction and expression of function, andthus are useful genes, which are available for regenerative medicineaiming at convenient regeneration of injured tissues.

Search was carried out for the genes whose expression frequencies weredifferent between developing and/or differentiating tissues and/orcells, and adult tissues and/or cells, by using the information of geneexpression frequency based on the database of the nucleotide sequencesof 770,546 clones shown above.

The result of comparative analysis of cDNA libraries derived from fetalbrain (FCBBF, FEBRA or OCBBF) and adult brain (BRACE, BRALZ, BRAMY,BRAWH, BRCAN, BRCOC, BRHIP, BRSSN, BRSTN or BRTHA) showed that the geneswhose expression levels were different between the two were thefollowing clones (Tables 16 to 36). ADRGL20020290, ADRGL20021910,ADRGL20023920, ADRGL20046760, ADRGL20062330, ADRGL20079060,ASTRO20009140, ASTRO20020240, ASTRO20027330, ASTRO20047510,ASTRO20055530, ASTRO20055570, ASTRO20055930, ASTRO20090680,BGGI120010750, BNGH420021680, BNGH420023870, BNGH420059680,BNGH420074600, BNGH420086030, BRACE10000510, BRACE20003310,BRACE20007330, BRACE20009050, BRACE20014450, BRACE20017790,BRACE20018810, BRACE20025820, BRACE20038920, BRACE20050870,BRACE20051600, BRACE20051930, BRACE20052430, BRACE20052530,BRACE20054080, BRACE20054480, BRACE20054600, BRACE20055560,BRACE20057870, BRACE20059110, BRACE20059810, BRACE20061620,BRACE20062580, BRACE20063540, BRACE20065470, BRACE20066360,BRACE20068710, BRACE20069000, BRACE20069110, BRACE20069440,BRACE20079200, BRACE20079370, BRACE20097540, BRACE20098860,BRACE20099070, BRACE20194670, BRACE20196180, BRACE20196960,BRACE20200770, BRACE20200970, BRACE20204670, BRACE20205840,BRACE20207420, BRACE20212450, BRACE20215410, BRACE20216700,BRACE20216950, BRACE20219360, BRAMY10000980, BRAMY10001730,BRAMY20000210, BRAMY20000250, BRAMY20001510, BRAMY20003540,BRAMY20003880, BRAMY20005080, BRAMY20013670, BRAMY20016780,BRAMY20020440, BRAMY20021580, BRAMY20023390, BRAMY20023640,BRAMY20024790, BRAMY20027390, BRAMY20027990, BRAMY20028530,BRAMY20028620, BRAMY20035380, BRAMY20035830, BRAMY20036530,BRAMY20036810, BRAMY20038980, BRAMY20039290, BRAMY20040580,BRAMY20043520, BRAMY20043630, BRAMY20044920, BRAMY20045210,BRAMY20045420, BRAMY20047560, BRAMY20050640, BRAMY20050940,BRAMY20051820, BRAMY20052440, BRAMY20053910, BRAMY20055760,BRAMY20056620, BRAMY20056840, BRAMY20063750, BRAMY20072440,BRAMY20072870, BRAMY20073080, BRAMY20074110, BRAMY20074860,BRAMY20076100, BRAMY20076130, BRAMY20076530, BRAMY20083330,BRAMY20083820, BRAMY20089770, BRAMY20091230, BRAMY20093490,BRAMY20094890, BRAMY20095080, BRAMY20095570, BRAMY20096930,BRAMY20100680, BRAMY20102900, BRAMY20107980, BRAMY20111780,BRAMY20117670, BRAMY20118410, BRAMY20118490, BRAMY20120170,BRAMY20123400, BRAMY20124970, BRAMY20125170, BRAMY20125360,BRAMY20125550, BRAMY20126910, BRAMY20127310, BRAMY20127760,BRAMY20134050, BRAMY20135720, BRAMY20137360, BRAMY20139440,BRAMY20139750, BRAMY20143870, BRAMY20152510, BRAMY20155500,BRAMY20158550, BRAMY20159250, BRAMY20160020, BRAMY20173480,BRAMY20190550, BRAMY20194680, BRAMY20204270, BRAMY20206340,BRAMY20219620, BRAMY20221600, BRAMY20223010, BRAMY20225250,BRAMY20225320, BRAMY20227230, BRAMY20227860, BRAMY20227960,BRAMY20231150, BRAMY20234820, BRAMY20237190, BRAMY20238630,BRAMY20243120, BRAMY20244490, BRAMY20245140, BRAMY20245350,BRAMY20245760, BRAMY20251210, BRAMY20251750, BRAMY20263000,BRAMY20267780, BRAMY20269040, BRAMY20271140, BRAMY20274510,BRAMY20285650, BRAMY20287400, BRAWH20014590, BRAWH20020470,BRAWH20020600, BRAWH20021910, BRAWH20025490, BRAWH20026010,BRAWH20027250, BRAWH20030000, BRAWH20039640, BRAWH20040680,BRAWH20047790, BRAWH20050740, BRAWH20055240, BRAWH20055330,BRAWH20055780, BRAWH20058120, BRAWH20063010, BRAWH20078080,BRAWH20078620, BRAWH20080580, BRAWH20082550, BRAWH20082920,BRAWH20093040, BRAWH20093070, BRAWH20094900, BRAWH20095900,BRAWH20173790, BRAWH20174330, BRAWH20175230, BBAWH20175340,BRAWH20176850, BRAWH20182670, BRAWH20183170, BRAWH20185260,BRAWH20185270, BRAWH20186010, BRAWH20188750, BRAWH20190530,BRAWH20190550, BRAWH20191980, BRCAN10000760, BRCAN10001050,BRCAN10001680, BRCAN20001480, BRCAN20004180, BRCAN20005230,BRCAN20005410, BRCOC10000400, BRCOC20000470, BRCOC20003600,BRHIP10000720, BRHIP10001040, BRHIP20000210, BRHIP20003590,BRHIP20005060, BRSSN20001970, BRSSN20005610, BRSSN20005660,BRSSN20066440, BRSSN20074640, BRSSN20091190, BRSSN20092440,BRSSN20093890, CTONG20032930, CTONG20035240, CTONG20044870,CTONG20063930, CTONG20069320, CTONG20070720, CTONG20071040,CTONG20071680, CTONG20074170, CTONG20078340, CTONG20079590,CTONG20080140, CTONG20085210, CTONG20133720, CTONG20165750,CTONG20168240, CTONG20170940, CTONG20183430, CTONG20186370,CTONG20188080, FCBBF10000230, FCBBF10002200, FCBBF10004760,FCBBF20018680, FCBBF20020440, FCBBF20021110, FCBBF20023490,FCBBF20028980, FCBBF20029280, FCBBF20032930, FCBBF20033360,FCBBF20035430, FCBBF20035490, FCBBF20036360, FCBBF20038230,FCBBF20038950, FCBBF20041380, FCBBF20043730, FCBBF20054390,FCBBF20056580, FCBBF20059660, FCBBF20061310, FCBBF20066340,FCBBF20070800, FCBBF20070950, FCBBF30000010, FCBBF30001020,FCBBF30001100, FCBBF30001150, FCBBF30002270, FCBBF30002280,FCBBF30002330, FCBBF30003610, FCBBF30004340, FCBBF30004730,FCBBF30005180, FCBBF30005360, FCBBF30005500, FCBBF30019140,FCBBF30019180, FCBBF30019240, FCBBF30021900, FCBBF30022680,FCBBF30026580, FCBBF30029250, FCBBF30035570, FCBBF30042610,FCBBF30048420, FCBBF30053300, FCBBF30056980, FCBBF30062490,FCBBF30063990, FCBBF30068210, FCBBF30071500, FCBBF30072440,FCBBF30072480, FCBBF30074530, FCBBF30074620, FCBBF30075970,FCBBF30076310, FCBBF30078600, FCBBF30079770, FCBBF30080730,FCBBF30081000, FCBBF30085560, FCBBF30088700, FCBBF30089380,FCBBF30091010, FCBBF30091520, FCBBF30093170, FCBBF30095410,FCBBF30099490, FCBBF30100080, FCBBF30100120, FCBBF30100410,FCBBF30101240, FCBBF30101300, FCBBF30105080, FCBBF30105440,FCBBF30105860, FCBBF30106950, FCBBF30107290, FCBBF30107330,FCBBF30114180, FCBBF30114850, FCBBF30115230, FCBBF30115920,FCBBF30118670, FCBBF30118890, FCBBF30125460, FCBBF30125880,FCBBF30128420, FCBBF30129010, FCBBF30130410, FCBBF30130580,FCBBF30132050, FCBBF30132660, FCBBF30135890, FCBBF30136230,FCBBF30138000, FCBBF30142290, FCBBF30143550, FCBBF30145670,FCBBF30151190, FCBBF30153170, FCBBF30157270, FCBBF30161780,FCBBF30164510, FCBBF30166220, FCBBF30169280, FCBBF30169870,FCBBF30170710, FCBBF30171230, FCBBF30172330, FCBBF30173960,FCBBF30175350, FCBBF30177290, FCBBF30179180, FCBBF30179740,FCBBF30181730, FCBBF30194370, FCBBF30194550, FCBBF30195690,FCBBF30195700, FCBBF30197840, FCBBF30198670, FCBBF30201630,FCBBF30212210, FCBBF30215240, FCBBF30220050, FCBBF30222910,FCBBF30223110, FCBBF30223210, FCBBF30225930, FCBBF30228940,FCBBF30230610, FCBBF30236670, FCBBF30250980, FCBBF30255680,FCBBF30257370, FCBBF30259050, FCBBF30260210, FCBBF30260480,FCBBF30263080, FCBBF30266510, FCBBF30271990, FCBBF30275590,FCBBF30282020, FCBBF30285930, FCBBF30287940, FCBBF40000610,FCBBF40001920, FCBBF40005000, FCBBF50000410, FCBBF50000610,FCBBF50001650, FCBBF50003530, FCBBF50004950, FEBRA20005040,FEBRA20007820, FEBRA20018670, FEBRA20026820, FEBRA20027070,FEBRA20029620, FEBRA20031000, FEBRA20031150, FEBRA20031280,FEBRA20031810, FEBRA20035200, FEBRA20035240, FEBRA20038220,FEBRA20038330, FEBRA20038970, FEBRA20039070, FEBRA20039260,FEBRA20040230, FEBRA20040260, FEBRA20040290, FEBRA20040560,FEBRA20045380, FEBRA20046200, FEBRA20046280, FEBRA20046510,FEBRA20057010, FEBRA20063720, FEBRA20076200, FEBRA20078180,FEBRA20078800, FEBRA20080860, FEBRA20082660, FEBRA20083410,FEBRA20084750, FEBRA20086600, FEBRA20087550, FEBRA20088610,FEBRA20088810, FEBRA20090160, FEBRA20090220, FEBRA20091620,FEBRA20092760, FEBRA20093270, FEBRA20093280, FEBRA20095410,FEBRA20098040, FEBRA20099860, FEBRA20101410, FEBRA20108020,FEBRA20108580, FEBRA20115930, FEBRA20116650, FEBRA20121200,FEBRA20121950, FEBRA20141980, FEBRA20150420, FEBRA20151750,FEBRA20163980, FEBRA20170240, FEBRA20172230, FEBRA20173330,FEBRA20175020, FEBRA20175330, FEBRA20177800, FEBRA20180510,FEBRA20182030, FEBRA20187460, FEBRA20191720, HCHON20002650,HCHON20002710, HEART10001490, HLUNG20008460, HLUNG20011460,HLUNG20014590, HLUNG20015070, HLUNG20015180, HLUNG20020850,HLUNG20028110, HLUNG20031620, HLUNG20032460, HLUNG20033060,HLUNG20041590, HLUNG20045340, HLUNG20056560, HLUNG20068120,HLUNG20081390, HLUNG20083480, HLUNG20085210, HLUNG20094130,KIDNE20080690, KIDNE20084030, KIDNE20086660, KIDNE20094670,KIDNE20134130, KIDNE20138450, KIDNE20140870, KIDNE20149780,KIDNE20170400, KIDNE20173430, MESAN20021860, MESAN20030350,MESAN20034440, MESAN20038520, MESAN20045750, MESAN20067430,MESAN20089260, MESAN20095800, NT2NE20026200, NT2NE20033150,NT2NE20042550, NT2NE20045190, NT2NE20053950, NT2NE20061030,NT2NE20069580, NT2NE20082130, NT2NE20082600, NT2NE20088030,NT2NE20092950, NT2NE20095230, NT2NE20108420, NT2NE20111190,NT2NE20112210, NT2NE20141040, NT2NE20177210, NT2NE20181800,NT2RI20021200, NT2RP70001120, NT2RP70001730, NT2RP70012830,NT2RP70035110, NT2RP70057500, NT2RP70075300, NT2RP70087140,NT2RP70090870, NTONG20002230, NTONG20017620, NTONG20049180,NTONG20055200, OCBBF20000740, OCBBF20001780, OCBBF20005220,OCBBF20009820, OCBBF20011860, OCBBF20012520, OCBBF20016390,OCBBF20016810, OCBBF20109450, OCBBF20109780, OCBBF20110210,OCBBF20110730, OCBBF20111370, OCBBF20111600, OCBBF20112280,OCBBF20112320, OCBBF20113110, OCBBF20115360, OCBBF20116250,OCBBF20117220, OCBBF20118720, OCBBF20119810, OCBBF20120010,OCBBF20120950, OCBBF20121910, OCBBF20123200, OCBBF20142290,OCBBF20147070, OCBBF20152330, OCBBF20155030, OCBBF20156450,OCBBF20157970, OCBBF20160380, OCBBF20165900, OCBBF20165910,OCBBF20166890, OCBBF20166900, OCBBF20167290, OCBBF20170350,OCBBF20174580, OCBBF20174890, OCBBF20175360, OCBBF20176650,OCBBF20177540, OCBBF20177910, OCBBF20182060, OCBBF20185630,OCBBF20188280, OCBBF20191950, PLACE60054820, PLACE60056910,PLACE60061370, PLACE60064740, PLACE60073090, PLACE60120280,PLACE60132200, PLACE60150510, PLACE60154450, PLACE60157310,PLACE60162100, PROST10002150, PROST20014150, PROST20016760,PROST20024250, PROST20035170, PROST20035830, PROST20042700,PROST20045700, PROST20050390, PROST20054660, PROST20078710,PROST20094000, PROST20097310, PROST20097840, PROST20103820,PROST20114100, PROST20130320, PROST20151370, PUAEN10000650,PUAEN10001640, PUAEN20003120, SKNMC20006350, SKNSH10001010,SKNSH20007160, SKNSH20030640, SKNSH20094350, SMINT20000070,SMINT20002320, SMINT20030740, SMINT20039050, SMINT20045890,SMINT20047290, SMINT20048720, SMINT20056240, SMINT20077920,SMINT20088690, SMINT20089210, SMINT20089600, SMINT20094150,SPLEN20005160, SPLEN20005370, SPLEN20012450, SPLEN20024930,SPLEN20040780, SPLEN20048800, SPLEN20055600, SPLEN20057830,SPLEN20063250, SPLEN20071820, SPLEN20073880, SPLEN20076470,SPLEN20104690, SPLEN20114190, SPLEN20125230, SPLEN20135030,SPLEN20136700, SPLEN20175920, SPLEN20181570, SPLEN20183020,SPLEN20187490, SPLEN20193490, SPLEN20193790, SPLEN20197740,SPLEN20200070, SPLEN20200340, TESOP10000350, TESTI20005980,TESTI20030440, TESTI20030610, TESTI20031410, TESTI20035330,TESTI20047370, TESTI20050400, TESTI20050720, TESTI20053780,TESTI20057430, TESTI20057590, TESTI20057840, TESTI20057880,TESTI20059080, TESTI20061200, TESTI20062580, TESTI20063410,TESTI20064530, TESTI20066280, TESTI20067480, TESTI20071630,TESTI20079980, TESTI20081890, TESTI20089290, TESTI20090180,TESTI20105130, TESTI20106170, TESTI20121040, TESTI20150920,TESTI20169500, TESTI20193080, TESTI20215310, TESTI20221790,TESTI20245860, TESTI20252690, TESTI20254090, TESTI20261160,TESTI20262150, TESTI20274960, THYMU20007750, THYMU20009460,THYMU20009710, THYMU20019260, THYMU20028410, THYMU20030460,THYMU20031330, THYMU20043440, THYMU20044100, THYMU20044520,THYMU20049060, THYMU20055460, THYMU20055740, THYMU20071120,THYMU20078020, THYMU20089900, THYMU20091040, THYMU20104480,THYMU20120240, THYMU20139160, THYMU20143230, THYMU20150190,THYMU20157620, THYMU20176010, TKIDN10001920, TRACH20012490,TRACH20021000, TRACH20026640, TRACH20058000, TRACH20090060,TRACH20159390, UMVEN10001380, UTERU10001060, UTERU20000230,UTERU20000950, UTERU20026620, UTERU20041970, UTERU20065470,UTERU20079240, UTERU20083020, UTERU20089300, UTERU20089390,UTERU20095100, UTERU20102260, UTERU20103200, UTERU20127150,UTERU20128560

The result of comparative analysis of cDNA libraries derived from fetalheart (FEHRT) and adult heart (HEART) showed that the genes whoseexpression levels were different between the two were the followingclones (Table 37). BRAMY20043630, BRAMY20072870, BRAMY20227860,BRAWH20093070, BRCAN10001680, FCBBF30053300, FEBRA20078800,FEBRA20090220, HCHON20000870, HEART10001420, HEART10001490,HEART20009590, HEART20019310, HEART20022200, HEART20031680,HEART20047640, HEART20063100, HEART20082570, HLUNG20083960,PLACE60088240, PLACE60120280, PROST20016760, PROST20035170,PROST20062820, PROST20127450, SKMUS20006790, SKMUS20008730,TESTI20270130

The result of comparative analysis of cDNA libraries derived from fetalkidney (FEKID) and adult kidney (KIDNE) showed that the genes whoseexpression levels were different between the two were the followingclones (Table 38). ASTRO20009140, BGGI120010750, BRACE20054480,BRACE20062580, BRACE20219360, BRAMY20001510, BRAMY20003540,BRAMY20003880, BRAMY20043630, BRAMY20204270, CTONG20033750,CTONG20039370, CTONG20045500, FCBBF20023490, FEBRA20039260,FEBRA20040290, HEART10001490, HLUNG20041590, HLUNG20068120,HLUNG20072450, HLUNG20083960, KIDNE20011600, KIDNE20016360,KIDNE20024380, KIDNE20027980, KIDNE20080690, KIDNE20081170,KIDNE20083150, KIDNE20083620, KIDNE20084030, KIDNE20084040,KIDNE20084730, KIDNE20084800, KIDNE20086490, KIDNE20086660,KIDNE20086970, KIDNE20087880, KIDNE20088240, KIDNE20089870,KIDNE20091090, KIDNE20094260, KIDNE20094670, KIDNE20095530,KIDNE20133460, KIDNE20133880, KIDNE20134130, KIDNE20134890,KIDNE20137310, KIDNE20138450, KIDNE20140870, KIDNE20141120,KIDNE20141700, KIDNE20142680, KIDNE20142900, KIDNE20143200,KIDNE20147170, KIDNE20148080, KIDNE20149780, KIDNE20150730,KIDNE20152440, KIDNE20154330, KIDNE20154830, KIDNE20155980,KIDNE20157100, KIDNE20160360, KIDNE20160960, KIDNE20163710,KIDNE20165390, KIDNE20169180, KIDNE20170400, KIDNE20173150,KIDNE20173430, KIDNE20176030, KIDNE20181670, KIDNE20182540,KIDNE20186170, KIDNE20188630, KIDNE20189890, KIDNE20189960,KIDNE20191870, OCBBF20174890, PLACE60073090, PLACE60181870,PROST20016760, PUAEN10000650, SKNMC20006350, SPLEN20017610,SPLEN20063250, SPLEN20126110, SPLEN20135030, TESTI20061200,TESTI20262150, THYMU10004280, THYMU20139160, TRACH20011010

The result of comparative analysis of cDNA libraries derived from fetallung (FELNG) and adult lung (HLUNG) showed that the genes whoseexpression levels were different between the two were the followingclones (Table 39). BRAMY20001510, BRAMY20043630, BRAMY20204270,BRAMY20227860, CTONG20029030, CTONG20168460, CTONG20186290,FEBRA20039260, FEBRA20078800, FEBRA20163980, HCHON20000870,HLUNG20008460, HLUNG20009260, HLUNG20009550, HLUNG20010130,HLUNG20011260, HLUNG20011440, HLUNG20011460, HLUNG20012140,HLUNG20014590, HLUNG20015070, HLUNG20015180, HLUNG20020500,HLUNG20020850, HLUNG20021450, HLUNG20023030, HLUNG20024050,HLUNG20025620, HLUNG20028110, HLUNG20029420, HLUNG20029490,HLUNG20030420, HLUNG20030490, HLUNG20030610, HLUNG20031620,HLUNG20032460, HLUNG20033060, HLUNG20033310, HLUNG20033350,HLUNG20034970, HLUNG20037140, HLUNG20037160, HLUNG20037780,HLUNG20038330, HLUNG20041540, HLUNG20041590, HLUNG20042730,HLUNG20045340, HLUNG20047070, HLUNG20050760, HLUNG20051330,HLUNG20052300, HLUNG20054790, HLUNG20055240, HLUNG20056560,HLUNG20057380, HLUNG20059240, HLUNG20060670, HLUNG20063700,HLUNG20065700, HLUNG20065990, HLUNG20067810, HLUNG20068120,HLUNG20069350, HLUNG20070410, HLUNG20072100, HLUNG20072190,HLUNG20072450, HLUNG20074330, HLUNG20079310, HLUNG20081390,HLUNG20081530, HLUNG20082350, HLUNG20083330, HLUNG20083480,HLUNG20083840, HLUNG20083960, HLUNG20084790, HLUNG20085210,HLUNG20088750, HLUNG20092530, HLUNG20093030, HLUNG20094130,KIDNE20142900, PROST20016760, PROST20052850, SKNMC20006350,SMINT20035050, SPLEN20012450, TESTI20057590, TESTI20061200,TESTI20067480, TESTI20116050, THYMU10004280, THYMU20010180,THYMU20139160, TRACH20011010, UTERU20016580, UTERU20127030

These genes are involved in regeneration of tissues and/or cells.

EXAMPLE 8 Expression Frequency Analysis by PCR

Specific PCR primers were prepared based on the full-length nucleotidesequences, and the expression frequency was analyzed by the ATAC-PCRmethod (Adaptor-tagged competitive PCR method: Nucleic Acids Research1997, 25 (22): 4694-4696; “DNA Micro-array and Advanced PCR Techniques”,Cell Technology, supplement, Eds., Muramatsu and Nawa (Shujunsha, 2000):104-112). Inflammation-related genes can be identified by revealing thegenes whose expression levels are altered depending on the presence ofan inflammation-inducing factor. Then, by using THP-1 cell line, whichis a cell line of monocyte line, and TNF-α, which is aninflammation-inducing factor, suitable for this system, the genes whoseexpression levels are altered depending on the presence of the factorwere searched for by the system.

THP-1 cell line (purchased from DAINIPPON PHARMACEUTICAL) was culturedto be confluent in RPMI1640 medium (sigma) containing 5% fetal calfserum (GIBCO BRL). Then, the medium was changed with the mediumcontaining 10 ng/ml TNF-α (human recombinant TNF-α; Pharmacia Biotech),and the culture was continued at 37° C. under 5% CO₂. After three hours,the cells were harvested, and total RNA was extracted from them by usingISOGEN reagent (Nippon Gene). The extraction was carried out accordingto the method in the document attached to ISOGEN reagent. In addition,total RNA was also extracted from the cells cultured without stimulationof TNF-α.

The genes involved in the onset of gastritis and gastroduodenal ulcerinduced by the infection of Helicobacter pylori to the epithelia ofstomach can be identified by revealing the genes whose expression levelsare altered depending on co-culturing the cells with Helicobacterpylori. A recent study has suggested that various substances derivedfrom Helicobacter pylori trigger the inflammation reaction. Inparticular, the members belonging to the family of genes called “cagpathogenicity island (cag PAI)” contribute to the activation of theNF-κB pathway (Gastroenterology 2000, 119: 97-108). Further, it has beenfound that cag PAI is involved in the onset of gastritis and the like bythe study using an animal model (Journal of Experimental Medicine 2000,192:1601-1610). Then, by using co-culture of a gastric cancer cell linewith cag PAI-positive Helicobacter pylori (TN2), suitable for thissystem, the genes whose expression levels are altered depending on thepresence of Helicobacter pylori were searched for by the system.Further, in order to study the involvement of cag PAI in the alterationsof gene expression levels depending on the co-culture with Helicobacterpylori, the altered expression levels were compared between the cellsco-cultured with a strain of Helicobacter pylori (TN2ΔcagE strain)having a mutation in cagE, which is one of the cag PAI genes, and thecag PAI-positive strain (TN2).

A gastric cancer cell line MKN45 (provided by the Cell Bank, RIKEN GENEBANK, The Institute of Physical and Chemical Research) was cultured tobe confluent in RPMI1640 medium (sigma) containing 10% fetal calf serum(GIBCO BRL). Then, the medium was changed with the medium containing100-fold excess (in terms of the number of cells or the number ofcolonies) of Helicobacter pylori (cag PAI positive strain (TN2) and cagEmutant (TN2ΔcagE): both were provided by Prof. Omata, Faculty ofMedicine, The University of Tokyo), as compared with the number of thecancer cells. The culture was continued at 37° C. under 5% CO₂. Afterthree hours, the cells were harvested, and total RNA was extracted fromthem by using ISOGEN reagent (Nippon Gene). The extraction was carriedout according to the method in the document attached to ISOGEN reagent.In addition, total RNA was also extracted from the cells culturedwithout Helicobacter pylori.

The analysis by the ATAC-PCR method was carried out basically accordingto “DNA Micro-array and Advanced PCR Techniques”, Cell Technology,supplement (Genome Science Series 1, Eds., Muramatsu and Nawa(Shujunsha, 2000): 104-112). Adapter ligation to the internal standardsample (sample to make the calibration curve for the clone of interest)and test sample was carried out in the two separate reaction systemsindicated below. The combination of 6 types of adapters (AD-1, AD-2,AD-3, AD-4, AD-5 and AD-6: see the sequences indicated below) and thesamples are as follows.

Reaction System A

-   AD1; internal standard, 10-fold-   AD2; THP-1 cells, unstimulated-   AD3; internal standard, 3-fold-   AD4; THP-1 cells, TNF-α stimulation for one hour-   AD5; THP-1 cells, TNF-α stimulation for three hours-   AD6; internal standard, 1-fold    Reaction System B-   AD1; internal standard, 1-fold-   AD2; MKN45 cells, unstimulated-   AD3; internal standard, 3-fold-   AD4; MKN45 cells, co-cultured with TN2 (Helicobacter pylori)-   AD5; internal standard, 10-fold-   AD6; MKN45 cells, co-cultured with TN2ΔcagE (cagE gene mutant)

Adapter Sequences: AD1; SEQ ID NO: 3941 5′-GTACATATTGTCGTTAGAACGCG-3′//SEQ ID NO: 3942 3′-CATGTATAACAGCAATCTTGCGCCTAG-5′// AD2; SEQ ID NO: 39435′-GTACATATTGTCGTTAGAACGCGACT-3′// SEQ ID NO: 39443′-CATGTATAACAGCAATCTTGCGCTGACTAG-5′// AD3; SEQ ID NO: 39455′-GTACATATTGTCGTTAGAACGCGCATACT-3′// SEQ ID NO: 39463′-CATGTATAACAGCAATCTTGCGCGTATGACTAG-5′// AD4; SEQ ID NO: 39475′-GTACATATTGTCGTTAGAACGCGATCCATACT-3′// SEQ ID NO: 39483′-CATGTATAACAGCAATCTTGCGCTAGGTATGACTAG-5′// AD5; SEQ ID NO: 39495′-GTACATATTGTCGTTAGAACGCGTCAATCCATACT-3′// SEQ ID NO: 39503′-CATGTATAACAGCAATCTTGCGCAGTTAGGTATGACTAG-5′// AD6; SEQ ID NO: 39515′-GTACATATTGTCGTTAGAACGCGTACTCAATCCATACT-3′// SEQ ID NO: 39523′-CATGTATAACAGCAATCTTGCGCATGAGTTAGGTATGACTAG-5′//

The internal standard sample used for this assay was a mixture of totalRNAs from tissues (or culture cells; all from UNITECH) of brain, kidney,NT2, testis, thymus, and trachea. RNA was prepared according to thestandard method.

The sequences of primers specific to the genes and the names of clonesof interest in the analysis are as follows. The gene specific primerswere designed to produce the PCR products of 70 to 200 bp, which arederived from the adapter-containing cDNA. The sequence ofadapter-specific primer (labeled with fluorescence (FAM)) used in thecompetitive PCR was GTACATATTGTCGTTAGAACGC (22 nucleotides; SEQ ID NO:3953). PCR was basically carried out with a cycling profile ofpreheating at 94° C. for 3 minutes, and 35 or 40 cycles of denaturationat 94° C. for 30 seconds/annealing at 50° C. for 60 seconds/extension at72° C. for 90 seconds.

The Nucleotide Sequences of Clone Specific Primers Used in theExperiments

Clone name, primer sequence and SEQ ID NO are indicated below in thisorder. Each is demarcated by a double slash mark (//).ADRGL20036380//CTACTCAAGGACAGCCACAC// SEQ ID NO: 3954ASTRO20045840//GGATGTAGTGGGAAACAATG// SEQ ID NO: 3955ASTRO20055930//TGCTTTTCATTCTCCTTAGT// SEQ ID NO: 3956ASTRO20088950//TACGTGCTCATTTACTTGGT// SEQ ID NO: 3957BNGH420052350//GCCAGTTTCTTTATGATTGA// SEQ ID NO: 3958BRACE20052530//AATGACTTCGTTAGGATGCC// SEQ ID NO: 3959BRACE20054080//GCTGTTGACTTCATTTGGAA// SEQ ID NO: 3960BRAMY20003880//TTGGTACTTATTCTGAGGCA// SEQ ID NO: 3961BRAMY20027390//GATTTTAGTGAAACATGCCA// SEQ ID NO: 3962BRAMY20028530//TTAAAACTGAGGACATTCTG// SEQ ID NO: 3963BRAMY20035380//AGAGAAGGCAGTCTAGCTTA// SEQ ID NO: 3964BRAMY20036530//AGGGTATGGTAACTTCTGCA// SEQ ID NO: 3965BRAMY20050940//AAAGGAGGGACTAGAAAACT// SEQ ID NO: 3966BRAMY20072440//ACTATGACGAGGGAACAAGA// SEQ ID NO: 3967BRAMY20096930//GAGGAGAACACAAGTATGGT// SEQ ID NO: 3968BRAMY20118410//AAGGTCACTTCTAAACACAC// SEQ ID NO: 3969BRAMY20237190//GGAGTGATTCAGGAGATGTG// SEQ ID NO: 3970BRAWH20055330//GCAACAGAGACTTTATTGGT// SEQ ID NO: 3971BRAWH20078620//GAGAGACTTATCACAGCCAT// SEQ ID NO: 3972BRAWH20190530//ATGGGATTCTGTGACTTCTC// SEQ ID NO: 3973BRCAN20001480//CAGCAACAGTAATGGGAATT// SEQ ID NO: 3974BRHIP10000720//AGGTTAGGATTTCTTTAGCA// SEQ ID NO: 3975BRHIP10001040//TACTTGGAGACAACAGGGAG// SEQ ID NO: 3976BRHIP20000210//GTGTTTGTGGGCATAGACAT// SEQ ID NO: 3977BRSSN20001970//AATGTATTCAGTTCCTTTCC// SEQ ID NO: 3978BRSSN20091190//GTGTCATCACTAGCACCAAG// SEQ ID NO: 3979CD34C20001750//TGGACTTAGGGACCTGACTC// SEQ ID NO: 3980CTONG20078340//CTCTTTACCTAGTTTGGTCA// SEQ ID NO: 3981CTONG20079590//TACTTATTTTCACAGGGGCC// SEQ ID NO: 3982CTONG20083980//CAGCATTTTCCTATATAGCC// SEQ ID NO: 3983CTONG20085210//CCAGAAGAGTAGCAAGAATT// SEQ ID NO: 3984DFNES20063460//CTATTTTAACCCCTGCCCTC// SEQ ID NO: 3985DFNES20072990//GGAGGTATCTATTAGGGTGA// SEQ ID NO: 3986FCBBF20029280//GACTGAGATGAACTGGAAGA// SEQ ID NO: 3987FCBBF20032930//TCACAATACAGTCCCCTAGT// SEQ ID NO: 3988FCBBF20036360//ATTTGTATCACTTTGGTGCA// SEQ ID NO: 3989FCBBF30022680//CTCCAGAAAATGCATGAATC// SEQ ID NO: 3990FCBBF30078600//CTTCAACAGTGCTTTTCCTT// SEQ ID NO: 3991FCBBF30105080//CTGTGCACCCACTCTTTATT// SEQ ID NO: 3992FCBBF30169870//TCCAGTATTTTCCACTTTGA// SEQ ID NO: 3993FCBBF30225930//ACTATTTTATGGTCACGGCC// SEQ ID NO: 3994FCBBF50000610//AGTTAACGTATCTGGCAAAG// SEQ ID NO: 3995FEBRA20007820//GTTTCTCACTGTCCTGTTTT// SEQ ID NO: 3996FEBRA20031280//ACTATTTTATGGTCACGGCC// SEQ ID NO: 3997FEBRA20031810//TGCAATCATCTCTGTATCCC// SEQ ID NO: 3998FEBRA20039260//GTCAGAACCCACTTCACATC// SEQ ID NO: 3999FEBRA20046280//TCTCTGTCCTGTTGTCTAAG// SEQ ID NO: 4000FEBRA20084750//TTAGCATGTACTGGGAAAGC// SEQ ID NO: 4001FEBRA20182030//AAAACACAAAATGACACCCC// SEQ ID NO: 4002HLUNG20041540//AAAGTTCCTCTGCATTCACC// SEQ ID NO: 4003HLUNG20092530//TTTTCATCCCAGAGTTATTA// SEQ ID NO: 4004KIDNE20084030//AGGGAATAACTTGCAGCTTG// SEQ ID NO: 4005KIDNE20084800//GTAATGTAGGGAGACTGCCG// SEQ ID NO: 4006KIDNE20134130//AATCCCCTCTTTTGTCTCAT// SEQ ID NO: 4007KIDNE20182540//ACAGATAGCCTGGATTGAAA// SEQ ID NO: 4008KIDNE20186170//TTGTATCTGAGCTGGGGTTT// SEQ ID NO: 4009KIDNE20188630//CCCTACATATCTCTACCCAT// SEQ ID NO: 4010LIVER20007750//TATTTAGAAACGCAGACCCC// SEQ ID NO: 4011MESAN20021220//TAGAAGTCAACAAAAGGCAC// SEQ ID NO: 4012MESAN20084150//TCCATAAGGCACAGATTTGA// SEQ ID NO: 4013NT2NE20059210//ATAATGACAATGCCAGTAGT// SEQ ID NO: 4014NT2NE20082130//TGAGGTACATCCAAATTAAA// SEQ ID NO: 4015NT2NE20092950//ATGATTACTCGGTTTCCAGA// SEQ ID NO: 4016NT2RP70031070//CAGTTAGTAGACAGACGGGG// SEQ ID NO: 4017OCBBF20012520//TCTGCCTGTAGTTGCCATTA// SEQ ID NO: 4018OCBBF20110210//AGGTGATAGGACTTTGTGCC// SEQ ID NO: 4019OCBBF20110730//TTAGATGCTCCCTAAGGTCC// SEQ ID NO: 4020OCBBF20155030//GCTAAAATCGTGCATCTGTA// SEQ ID NO: 4021OCBBF20165900//AGTTTTGTATCTCCTTGTCA// SEQ ID NO: 4022OCBBF20170350//TAAGATGGAGTTCAGGGGAG// SEQ ID NO: 4023OCBBF20176650//GCACACAGGCAAATTCTAGT// SEQ ID NO: 4024PLACE60006300//TTCTGTAATAAGGGCTGTCA// SEQ ID NO: 4025PLACE60061370//TGTTCACAAATGGCATAAAA// SEQ ID NO: 4026PROST20011160//CTACTAACTCAACCACGCAT// SEQ ID NO: 4027PROST20041460//CCATTTACGTCACCTCTCTG// SEQ ID NO: 4028PROST20065100//ACTATTTTATGGTCACGGCC// SEQ ID NO: 4029PROST20075280//ACGTTGACTCTGATAGCCTG// SEQ ID NO: 4030PROST20106060//AATTCTTTTGACATTGCTTG// SEQ ID NO: 4031PROST20110120//GATAAATTCAGCAAGAGCAT// SEQ ID NO: 4032SKMUS20091900//AACTCTGCACTCCATAACTG// SEQ ID NO: 4033SMINT20024140//AAGCCTCTAAAAGTCAACAC// SEQ ID NO: 4034SMINT20092160//TTAAACAAGTGAGCCTCAGA// SEQ ID NO: 4035SPLEN20040780//TTTCCTGTTTGGTTAGTTTT// SEQ ID NO: 4036SPLEN20110860//CTGACGGAAAACTTCTAATT// SEQ ID NO: 4037SPLEN20177400//ATATCTGGTTGTTGGGTTTT// SEQ ID NO: 4038TESTI20038240//GTCTGTCTTGATGGATTGGA// SEQ ID NO: 4039TESTI20043130//AACTATCAGACTGCAAGAGC// SEQ ID NO: 4040TESTI20046540//GGTAGCCAATAGCAAACAGG// SEQ ID NO: 4041TESTI20047370//ACGTTGCATAATCCTCAGTC// SEQ ID NO: 4042TESTI20057200//AGTCCCAGTCTCTAGTTCGG// SEQ ID NO: 4043TESTI20057590//ACATTTTGGTATTGACACTT// SEQ ID NO: 4044TESTI20113940//GTCAGTCCACCTTACTCTTT// SEQ ID NO: 4045TESTI20149880//CAAACGATTACGACACAAAA// SEQ ID NO: 4046TESTI20151800//CGTTCCTCAGGTAGCAAGAT// SEQ ID NO: 4047TESTI20173050//ACATGGCTGAAGGTGATTTT// SEQ ID NO: 4048TESTI20198600//TTTAGAAACATTGGCATCAG// SEQ ID NO: 4049TESTI20257910//CTGCCTAGAGTAGAACAAAA// SEQ ID NO: 4050TESTI20262940//CTCCCAATCTCAAACACAAG// SEQ ID NO: 4051THYMU20046770//CTTCTGCCGAGTTTGTGTAA// SEQ ID NO: 4052THYMU20058550//GATGCTGAGAAGGTGTTAGT// SEQ ID NO: 4053THYMU20062520//AGTCTCAGGATGGGTAAAGG// SEQ ID NO: 4054THYMU20062770//AGAGTTAAGAACCGAGGGAT// SEQ ID NO: 4055THYMU20078240//CAAGCCAGGGAGATAGACAT// SEQ ID NO: 4056THYMU20150190//TACTACAATGTGGGCTACGG// SEQ ID NO: 4057TRACH20125620//CCACATTGTAAACAGTCCTT// SEQ ID NO: 4058TRACH20149740//AGATACATTTTCCGTCAAGC// SEQ ID NO: 4059TRACH20190460//CCAGAAGAGTAGCAAGAATT// SEQ ID NO: 4060UTERU20045200//ATTCAACTAAAACAAAGCTG// SEQ ID NO: 4061UTERU20064120//ACCCAGAAAAGAGATGAGAA// SEQ ID NO: 4062UTERU20103200//CTGTTCCTGGCAAATAAGAG// SEQ ID NO: 4063ADRGL20046760//ATGTGAAGGAATGATGTACT// SEQ ID NO: 4064ASTRO20055530//GAATAATGAAGGGGACCAGA// SEQ ID NO: 4065BRAMY20076130//CCTTTCATGTCTCAGTATTT// SEQ ID NO: 4066CTONG20170940//ATACGTCAGAGGACACATGC// SEQ ID NO: 4067FCBBF20033360//TCCGTAGCAGTAGAAACATC// SEQ ID NO: 4068FCBBF30257370//CAGGTATGCTTGGAGTTTCA// SEQ ID NO: 4069FCBBF5000165O//CGTGATTAGGAAGGGACAGT// SEQ ID NO: 4070FEBRA20040290//CCCAAGAACGAAACAAAACT// SEQ ID NO: 4071FEBRA20063720//AATAATGCCCACCTATAAAA// SEQ ID NO: 4072FEBRA20098040//GAGGGGAATTGTCAGTACAC// SEQ ID NO: 4073FEBRA20108580//TCATTTTGTCTAGTGCCCAT// SEQ ID NO: 4074MESAN20021860//ACACATTCCCATCAATAGGT// SEQ ID NO: 4075MESAN20067430//AGCTAAGGAGGTTTTCACAT// SEQ ID NO: 4076NT2NE20045190//GGAATATGTTGGGCTAGTTA// SEQ ID NO: 4077PROST20016760//AACTTCATCCATTCCAACTG// SEQ ID NO: 4078SKNSH2000716O//TTAAACCAACATTGAGGAAA// SEQ ID NO: 4079SMINT20006020//CTTGGTTGTCCCCTTTCTAG// SEQ ID NO: 4080TESTI20059370//GGCTGACTTTTCTCCTACAG// SEQ ID NO: 4081TESTI20103690//CCACTTTATTTCTCCTCCCT// SEQ ID NO: 4082TESTI20254480//GTGGACACAACTTGCTTTAC// SEQ ID NO: 4083THYMU10004280//GAGAGTCTGCCTAGCTGTGT// SEQ ID NO: 4084THYMU20030460//GCCCATGTGAGTAGGTGTAG// SEQ ID NO: 4085TRACH20090060//AGGGCCAACTTAAATCTCTG// SEQ ID NO: 4086UTERU20041970//GATAAACCCCAAACATGAAA// SEQ ID NO: 4087BRAMY20125360//GACAGACTAAAACGTTGAGC// SEQ ID NO: 4088OCBBF20142290//CCAAGGAGAGTCAGTGACAG// SEQ ID NO: 4089SKMUS20006790//TTCAAAAGCAGAGACTCCCT// SEQ ID NO: 4090TESTI20030610//TGAACTCAGTACCAGGCTTG// SEQ ID NO: 4091UTERU20026620//GAGATTCCCTAGTGGTGGTT// SEQ ID NO: 4092

The result of expression frequency analysis is shown in Table 40. Theclones not shown in the table contain clones whose expression levelscould not be measured because the levels were too low or the sizes ofthe PCR products were different from the expected. It was confirmed thatthe expression levels of IL-8 gene used as a positive control gene wereelevated.

The result obtained by the search for the genes whose expression levelswere altered depending on the presence of TNF-α in culturing THP-1 cell,which is a human monocyte cell line, showed that the clones whoseexpression levels were elevated by twofold or more one or three hoursafter the stimulation (the clones whose expression levels were 0.1 orlower both before and after the stimulation were excluded), wereASTRO20055530, ASTRO20055930, ASTRO20088950, BRAMY20027390,BRAMY20076130, BRAMY20118410, BRAMY20125360, BRAMY20237190,BRCAN20001480, BRHIP10000720, CD34C20001750, CTONG20078340,CTONG20085210, DFNES20063460, FCBBF20029280, FCBBF20033360,FCBBF30078600, FEBRA20007820, FEBRA20031280, FEBRA20031810,FEBRA20040290, HLUNG20041540, HLUNG20092530, MESAN20021860,MESAN20067430, MESAN20084150, NT2NE20092950, NT2RP70031070,OCBBF20012520, OCBBF20142290, OCBBF20165900, OCBBF20170350,OCBBF20176650, PLACE60006300, PROST20011160, PROST20106060,SPLEN20040780, SPLEN20110860, SPLEN20177400, TESTI20030610,TESTI20043130, TESTI20059370, TESTI20254480, THYMU10004280,THYMU20030460, THYMU20062520, THYMU20078240, THYMU20150190,TRACH20090060, TRACH20125620, UTERU20026620, UTERU20045200,UTERU20064120, UTERU20103200.

On the other hand, in particular cases where the expression levels wererelatively high in the unstimulated cells (the relative value was 1 orhigher), the clones whose expression levels were decreased by twofold ormore by the TNF-α stimulation (the clones whose expression levels wereincreased 1 or 3 hours after the stimulation were excluded) wereBNGH420052350, BRACE20052530, BRAMY20003880, CTONG20170940,FCBBF30022680, FCBBF30225930, FCBBF30257370, FEBRA20046280,KIDNE20084030, KIDNE20188630, NT2NE20082130, OCBBF20110210,PLACE60061370, PROST20041460, PROST20075280, PROST20110120,SMINT20006020, TESTI20046540, TESTI20057200, TESTI20113940,TESTI20257910, TESTI20262940, TRACH20149740.

These clones were thus revealed to be involved in the inflammationreaction induced by TNF-α.

The result obtained by the search for the genes whose expression levelswere altered depending on co-culturing gastric cancer cell line MKN45with cag PAI positive Helicobacter pylori (TN2), showed that the cloneswhose expression levels were elevated by twofold or more (the cloneswhose expression levels were 0.1 or lower both before and after thestimulation were excluded), were BRAMY20028530, BRAMY20035380,OCBBF20170350, PROST20011160, SKMUS20091900, SPLEN20040780,THYMU20078240, TRACH20190460, UTERU20045200, UTERU20064120,ASTRO20055530, CTONG20170940, FEBRA20040290, MESAN20067430,PROST20016760, THYMU10004280, TRACH20090060, UTERU20041970,OCBBF20142290, TESTI20030610.

Of these clones, the expression levels of BRAMY20035380, SKMUS20091900,SPLEN20040780, UTERU20064120, CTONG20170940, OCBBF20142290,TESTI20030610 were not increased by the co-culture with the cagE mutant(TN2ΔcagE). There may be the possibility that the expression levels ofthe 7 clones are altered via the NF-κB pathway. Among them, theexpression levels of OCBBF20142290, SPLEN20040780, TESTI20030610,UTERU20064120 were also increased when human monocyte cell line THP-1was stimulated with TNF-α.

On the other hand, in particular cases where the expression levels wererelatively high in the unstimulated cells (the relative value was 1 orhigher), the clones whose expression levels were decreased by twofold ormore in the presence of Helicobacter pylori were ASTRO20088950,BRACE20052530, BRAMY20003880, BRAMY20027390, BRAMY20036530,BRAMY20118410, BRHIP20000210, FCBBF20032930, FCBBF30022680,FCBBF30169870, FEBRA20182030, KIDNE20182540, LIVER20007750,MESAN20021220, NT2NE20059210, NT2NE20082130, OCBBF20155030,PROST20065100, PROST20075280, SPLEN20110860, TESTI20057200,TESTI20113940, TESTI20149880, TESTI20151800, TESTI20198600,TESTI20257910, THYMU20046770, THYMU20058550, THYMU20150190,FCBBF20033360, FCBBF30257370, FEBRA20098040, SMINT20006020.

These clones are involved in gastritis or gastroduodenal ulcer. TABLE 3Clone ID CD34C D30ST D60ST D90ST ASTRO20010290 0 55.437 0 0BRAMY20036530 0 33.144 0 0 BRAMY20043630 0 0 0 13.575 BRAMY20089770 0 00 63.803 BRAMY20190550 0 0 0 31.089 CD34C20001750 100 0 0 0FCBBF20066340 0 0 0 76.503 FEBRA20040290 0 0 0 14.912 HLUNG20015180 0 00 8.491 HLUNG20041590 0 0 0 18.349 HLUNG20052300 0 36.241 0 0KIDNE20084040 0 0 0 65.916 MESAN20021860 0 0 0 56.046 MESAN20027240 0 00 33.731 NTONG20055200 0 0 0 19.731 PROST20016760 0 0 0 15.442PUAEN10001640 0 34.074 0 0 SMINT20006020 0 7.702 0 9.021 SMINT20028840 068.605 0 0 SMINT20035050 0 9.417 0 11.029 SPLEN20181570 81.506 0 0 0TESTI20064530 0 0 77.29 0 TESTI20210030 0 0 0 90.471 THYMU20029830 042.091 0 0 THYMU20139160 0 0 0 3.486 TRACH20051590 0 0 0 75.217

TABLE 4 Clone ID NT2RM NT2RP NT2RI NT2NE ADRGL20023920 0 6.69 0 0ASTRO20009140 0 0 13.389 0 BNGH420077980 0 0 20.754 0 BNGH420086030 0 00 13.322 BRACE20062580 0 0 3.585 2.717 BRACE20079370 0 0 9.312 14.111BRACE20215410 0 0 27.196 0 BRAMY20003540 0 0 3.208 4.861 BRAMY20043630 00 2.408 0 BRAMY20076130 0 0 6.601 0 BRAMY20095080 0 0 25.606 0BRAMY20227860 0 2.798 6.17 3.596 BRAWH20082550 0 0 0 9.738 BRHIP100010400 0 0 2.323 BRSSN20005610 0 22.393 0 0 CTONG20027660 0 0 50.642 0CTONG20044230 0 0 50.642 0 CTONG20066110 0 0 19.131 0 CTONG20079590 014.297 29.102 0 CTONG20084660 0 0 2.553 0 CTONG20133720 0 8.861 0 9.111CTONG20165750 0 9.056 0 0 CTONG20188080 0 10.319 0 0 FCBBF20023490 07.376 0 7.583 FCBBF20033360 0 0 5.015 0 FCBBF20059660 0 0 0 66.235FCBBF20070950 0 0 15.367 0 FCBBF30004340 0 0 0 8.778 FCBBF30095410 079.235 0 0 FCBBF30125460 0 0 0 9.321 FCBBF30179180 0 0 56.418 0FCBBF30236670 0 1.325 4.494 2.724 FCBBF30257370 0 19.522 0 0FCBBF50000610 0 0 56.418 0 FCBBF50001650 0 0 0 22.181 FEBRA20038330 016.124 0 0 FEBRA20039260 0 7.162 2.43 0 FEBRA20063720 0 12.258 0 0FEBRA20090220 0 4.602 3.122 4.732 FEBRA20150420 0 0 33.26 0HEART10001490 0 0 9.27 0 HLUNG20032460 0 0 0 21.278 HLUNG20041590 0 0 04.932 KIDNE20089870 0 0 0 4.145 MESAN20016270 0 0 39.208 0 MESAN200218600 0 0 7.532 MESAN20060430 0 0 24.385 0 MESAN20067430 0 0 0 9.568NT2NE20018740 0 0 0 100 NT2NE20018890 0 0 0 100 NT2NE20021860 0 0 0 100NT2NE20026200 0 0 0.808 2.449 NT2NE20026510 0 0 0 100 NT2NE20028700 0 00 22.223 NT2NE20033150 0 0 0 50.133 NT2NE20037050 0 0 0 100NT2NE20038870 0 0 0 100 NT2NE20039210 0 0 0 100 NT2NE20042550 0 0 059.083 NT2NE20045190 0 0 5.05 15.306 NT2NE20047870 0 0 0 100NT2NE20053230 0 0 0 100 NT2NE20053950 0 20.953 0 21.544 NT2NE20059210 00 0 100 NT2NE20059680 0 0 0 100 NT2NE20060750 0 0 0 100 NT2NE20061030 039.18 0 40.284 NT2NE20062880 0 0 0 100 NT2NE20064780 0 0 0 100NT2NE20066590 0 0 0 100 NT2NE20069580 0 0 0 59.083 NT2NE20070520 0 0 0100 NT2NE20073650 0 0 0 100 NT2NE20077250 0 0 0 100 NT2NE20077270 0 0 0100 NT2NE20077860 0 0 0 100 NT2NE20079670 0 0 0 100 NT2NE20080770 0 0 0100 NT2NE20082130 0 0 0 38.09 NT2NE20082600 0 0 0 66.235 NT2NE20086070 00 0 100 NT2NE20087270 0 0 0 100 NT2NE20087850 0 0 0 100 NT2NE20088030 00 0 60.425 NT2NE20092950 0 20.298 0 20.87 NT2NE20095230 0 0 0 55.188NT2NE20104000 0 0 0 100 NT2NE20107810 0 0 0 100 NT2NE20108420 0 0 045.407 NT2NE20111190 0 0 0 61.289 NT2NE20112210 0 0 0 26.669NT2NE20114850 0 0 0 100 NT2NE20117580 0 0 0 100 NT2NE20119980 0 0 0 100NT2NE20123610 0 0 0 100 NT2NE20124570 0 0 0 100 NT2NE20126030 0 0 0 100NT2NE20127900 0 0 16.514 25.025 NT2NE20140130 0 0 0 100 NT2NE20140280 00 0 100 NT2NE20141040 0 0 0 36.013 NT2NE20145250 0 0 0 100 NT2NE201465100 0 0 100 NT2NE20148690 0 0 0 67.567 NT2NE20149500 0 0 0 100NT2NE20150610 0 0 0 100 NT2NE20152620 0 0 0 100 NT2NE20153620 0 0 060.858 NT2NE20155650 0 0 0 100 NT2NE20157120 0 0 0 100 NT2NE20165190 0 00 100 NT2NE20167660 0 0 0 100 NT2NE20173970 0 0 0 100 NT2NE20177210 0 00 43.734 NT2NE20181760 0 0 0 100 NT2NE20181800 0 0 0 46.215NT2NE20184720 0 0 0 100 NT2RI20016240 0 0 100 0 NT2RI20021200 0 0 8.8440 NT2RI20033920 0 0 100 0 NT2RI20093010 0 0 100 0 NT2RP70001120 0 32.5730 0 NT2RP70001730 0 15.462 0 0 NT2RP70003110 0 24.333 0 0 NT2RP700128300 5.639 0 5.798 NT2RP70022820 0 66.955 0 0 NT2RP70027790 0 60.194 0 0NT2RP70029780 0 100 0 0 NT2RP70030840 0 100 0 0 NT2RP70031070 0 100 0 0NT2RP70031340 0 100 0 0 NT2RP70031480 0 100 0 0 NT2RP70035110 0 23.442 00 NT2RP70046410 0 64.358 0 0 NT2RP70049610 0 100 0 0 NT2RP70056290 0 1000 0 NT2RP70056690 0 100 0 0 NT2RP70057500 0 13.6 0 0 NT2RP70064570 060.194 0 0 NT2RP70074800 0 100 0 0 NT2RP70075300 0 6.726 0 0NT2RP70075800 0 100 0 0 NT2RP70080150 0 100 0 0 NT2RP70084540 0 100 0 0NT2RP70087140 0 7.444 15.153 7.654 NT2RP70090870 0 17.122 11.617 0OCBBF20001780 0 0 15.351 0 OCBBF20009820 84.348 0 0 0 OCBBF20142290 0 00 14.577 OCBBF20155030 0 49.439 0 0 OCBBF20175360 0 0 0 20.881OCBBF20177540 0 25.509 0 0 OCBBF20177910 0 0 23.505 0 PLACE60054820 0 020.089 0 PLACE60061370 0 18.07 0 0 PLACE60073090 0 10.617 0 0PLACE60162100 0 0 0 37.629 PROST20011800 0 0 0 50.542 PROST20045700 0 00 44.59 PROST20078710 0 0 0 33.633 PROST20094000 0 0 18.34 0PUAEN10000650 0 3.375 0 0 PUAEN10001640 0 5.216 3.539 0 SKNMC20006350 02.005 2.041 4.124 SMINT20016150 0 49.972 0 0 SMINT20030740 0 5.712 0 0SMINT20035510 0 0 28.984 0 SMINT20039050 0 0 18.576 9.383 SMINT200472900 39.6 0 0 SPLEN20063250 0 8.081 8.225 8.309 SPLEN20117580 0 0 0 24.462SPLEN20125230 0 0 21.559 0 TESTI20030610 0 0 0 12.205 TESTI20043910 0 00 45.963 TESTI20066280 0 0 0 30.676 TESTI20067480 0 8.861 0 0TESTI20105130 0 0 0 2.5 TESTI20106170 0 13.104 0 0 TESTI20143180 0 062.741 0 TESTI20221790 0 0 39.167 0 TESTI20254090 0 0 0 19.063TESTI20274960 0 0 38.685 0 THYMU10004280 0 3.573 0 0 THYMU20007020 0 071.017 0 THYMU20104480 0 0 29.694 0 THYMU20139160 0 1.822 0.618 0TRACH20026640 0 0 7.476 0 UTERU10001060 0 0 19.967 0 UTERU20026620 010.41 0 10.703 UTERU20079240 0 0 0 19.734 UTERU20083020 0 7.182 0 0UTERU20102260 0 0 0 23.706 UTERU20132620 0 48.06 0 0

TABLE 5 Clone ID BEAST TBAES CTONG20070780 0 97.283 CTONG20084660 089.108 HLUNG20045340 0 85.362 TESTI20047370 0 71.55

TABLE 6 Clone ID CERVX TCERX SMINT20030740 0 65.795

TABLE 7 Clone ID COLON TCOLN UTERU2004037 68.149 0

TABLE 8 Clone ID NESOP TESOP HLUNG20015180 51.695 0 NESOP20004520 100 0NESOP20005040 100 0 TESOP10000350 0 86.127 TESOP10001600 0 100THYMU20071120 0 81.712

TABLE 9 Clone ID KIDNE TKIDN ASTRO20009140 19.518 0 ASTRO20027330 030.903 ASTRO20055930 0 36.981 BGGI120010750 4.532 0 BNGH420074600 011.358 BRACE20050870 0 15.884 BRACE20054480 29.719 0 BRACE20062580 2.6130 BRACE20219360 59.494 0 BRAMY20003540 4.676 0 BRAMY20003880 16.88241.527 BRAMY20043630 3.51 0 BRAMY20055760 0 65.196 BRAMY20125360 032.672 BRAMY20190550 0 19.772 BRAMY20204270 3.618 0 BRAMY20227860 04.255 BRAWH20014590 0 23.509 BRAWH20093070 0 14.759 BRHIP10001040 05.496 CTONG20033750 59.93 0 CTONG20039370 59.93 0 CTONG20045500 59.93 0CTONG20079590 0 17.392 FCBBF20023490 14.59 0 FCBBF30004340 0 10.386FCBBF30106950 0 69.888 FCBBF30115230 0 69.888 FCBBF30169280 0 38.857FCBBF30225930 0 50.898 FCBBF30282020 0 53.714 FEBRA20038330 0 6.538FEBRA20039260 7.084 0 FEBRA20040290 7.711 0 FEBRA20082660 0 77.359FEBRA20121200 0 63.078 FEBRA20170240 0 63.078 HEART10001490 20.269 0HLUNG20041590 4.744 0 HLUNG20068120 11.84 0 HLUNG20072450 3.599 0HLUNG20083480 0 15.004 HLUNG20083960 18.946 0 KIDNE20011600 100 0KIDNE20016360 59.589 0 KIDNE20024380 100 0 KIDNE20027980 100 0KIDNE20080690 5.861 0 KIDNE20081170 100 0 KIDNE20083150 100 0KIDNE20083620 100 0 KIDNE20084030 40.03 0 KIDNE20084040 34.084 0KIDNE20084730 100 0 KIDNE20084800 100 0 KIDNE20086490 87.61 0KIDNE20086660 47.013 0 KIDNE20086970 100 0 KIDNE20087880 28.683 0KIDNE20088240 100 0 KIDNE20089870 3.987 0 KIDNE20091090 100 0KIDNE20094260 100 0 KIDNE20094670 59.494 0 KIDNE20095530 100 0KIDNE20133460 100 0 KIDNE20133880 100 0 KIDNE20134130 65.363 0KIDNE20134890 100 0 KIDNE20137310 100 0 KIDNE20138450 38.971 0KIDNE20140870 22.93 0 KIDNE20141120 100 0 KIDNE20141700 100 0KIDNE20142680 100 0 KIDNE20142680 100 0 KIDNE20142900 31.732 0KIDNE20143200 100 0 KIDNE20147170 100 0 KIDNE20148080 100 0KIDNE20149780 60.365 0 KIDNE20150730 100 0 KIDNE20152440 100 0KIDNE20154330 100 0 KIDNE20154830 100 0 KIDNE20155980 100 0KIDNE20157100 100 0 KIDNE20160360 100 0 KIDNE20160960 100 0KIDNE20163710 100 0 KIDNE20165390 100 0 KIDNE20169180 100 0KIDNE20170400 19.556 0 KIDNE20173150 100 0 KIDNE20173430 36.673 0KIDNE20176030 100 0 KIDNE20181670 100 0 KIDNE20182540 100 0KIDNE20186170 100 0 KIDNE20188630 100 0 KIDNE20189890 100 0KIDNE20189960 100 0 KIDNE20191870 100 0 MESAN20038520 0 11.358MESAN20041380 0 53.625 OCBBF20016390 0 23.211 OCBBF20142290 0 8.623OCBBF20174890 32.241 0 PLACE60061370 0 21.981 PLACE60073090 10.501 0PLACE60181870 49.921 0 PROST20016760 3.992 9.82 PUAEN10000650 6.676 0SMINT20039050 0 11.102 SMINT20089210 0 12.885 SPLEN20017610 42.429 0SPLEN20024930 0 22.541 SPLEN20057830 0 35 SPLEN20063250 3.996 0SPLEN20126110 50.05 0 SPLEN20135030 31.695 0 SPLEN20136700 0 39.807TESTI20070740 0 75.118 TESTI20262150 40.96 0 THYMU20009500 0 24.928THYMU20019260 0 36.869 THYMU20157620 0 19.973 TKIDN10000620 0 100TKIDN10001710 0 100 TKIDN10001920 0 36.869 TRACH20011010 10.647 0UMVEN10001380 0 4.196

TABLE 10 Clone ID LIVER TLIVE CTONG20069320 20.862 0 FCBBF30236670 3.2570 FEBRA20038220 77.547 0 FEBRA20039260 8.806 0 KIDNE20087880 71.317 0LIVER20006260 100 0 LIVER20007690 85.922 0 LIVER20007750 100 0LIVER20010510 100 0 LIVER20010760 100 0 LIVER20010990 100 0LIVER20011640 100 0 LIVER20013890 100 0 LIVER20026440 100 0LIVER20030650 100 0 LIVER20032340 100 0 LIVER20038000 100 0LIVER20040740 100 0 LIVER20055270 100 0 MESAN20027240 21.684 0NT2RI20021200 16.028 0 SKMUS20006790 6.063 0 TESTI20035330 22.045 0THYMU10004280 8.787 4.346 THYMU20029830 31.692 0

TABLE 11 Clone ID HLUNG TLUNG HLUNG20052300 23.611 0 SMINT20035050 6.1350 HLUNG20041590 10.207 0 PROST20016760 8.589 0 BRAMY20043630 15.102 0HLUNG20015180 4.723 0 THYMU20139160 1.939 0 HLUNG20020850 67.488 0HLUNG20032460 44.037 0 BRAMY20204270 7.785 0 BRAMY20001510 5.948 0BRAMY20227860 1.488 0 CTONG20029030 28.504 0 CTONG20168460 76.291 0CTONG20186290 61.67 0 FEBRA20039260 7.62 0 FEBRA20078800 33.686 0FEBRA20163980 38.327 0 HCHON20000870 23.288 0 HLUNG20008460 67.54 0HLUNG20009260 100 0 HLUNG20009550 100 0 HLUNG20010130 100 0HLUNG20011260 100 0 HLUNG20011440 100 0 HLUNG20011460 76.577 0HLUNG20012140 100 0 HLUNG20014590 36.045 0 HLUNG20015070 17.804 0HLUNG20020500 100 0 HLUNG20021450 68.006 0 HLUNG20023030 100 0HLUNG20024050 100 0 HLUNG20025620 100 0 HLUNG20028110 76.618 0HLUNG20029420 100 0 HLUNG20029490 81.173 0 HLUNG20030420 100 0HLUNG20030490 100 0 HLUNG20030610 100 0 HLUNG20031620 80.237 0HLUNG20033060 36.529 0 HLUNG20033310 100 0 HLUNG20033350 100 0HLUNG20034970 79.349 0 HLUNG20037140 100 0 HLUNG20037160 100 0HLUNG20037780 44.761 0 HLUNG20038330 100 0 HLUNG20041540 100 0HLUNG20042730 100 0 HLUNG20045340 7.67 0 HLUNG20047070 100 0HLUNG20050760 100 0 HLUNG20051330 100 0 HLUNG20054790 100 0HLUNG20055240 100 0 HLUNG20056560 75.961 0 HLUNG20057380 100 0HLUNG20059240 100 0 HLUNG20060670 100 0 HLUNG20063700 100 0HLUNG20065700 62.8 0 HLUNG20065990 100 0 HLUNG20067810 100 0HLUNG20068120 50.947 0 HLUNG20069350 100 0 HLUNG20070410 100 0HLUNG20072100 54.241 0 HLUNG20072190 79.349 0 HLUNG20072450 7.744 0HLUNG20074330 100 0 HLUNG20079310 100 0 HLUNG20081390 66.429 0HLUNG20081530 100 0 HLUNG20082350 100 0 HLUNG20083330 100 0HLUNG20083480 13.123 0 HLUNG20083840 100 0 HLUNG20083960 40.76 0HLUNG20084790 100 0 HLUNG20085210 50.993 0 HLUNG20088750 100 0HLUNG20092530 100 0 HLUNG20093030 100 0 HLUNG20094130 75.987 0KIDNE20142900 68.268 0 PROST20052850 57.701 0 SKNMC20006350 2.134 0SPLEN20012450 25.695 0 TESTI20057590 17.804 0 TESTI20061200 29.123 0TESTI20067480 18.856 0 TESTI20116050 30.168 0 THYMU10004280 7.603 0THYMU20010180 79.349 0 TRACH20011010 22.907 0 UTERU20016580 43.64 0UTERU20127030 66.318 0

TABLE 12 Clone ID NOVAR TOVAR KIDNE20089870 91.868 0 NT2RP7007530076.633 0 TESTI20132310 94.177 0

TABLE 13 Clone ID STOMA TSTOM BNGH420087430 0 91.629 BRAMY20227860 1.350 BRAWH20027250 42.096 0 CTONG20174440 26.346 0 FEBRA20090220 4.442 0PUAEN10000650 13.031 0 SMINT20023110 72.094 0 SMINT20030740 5.514 0SMINT20045890 34.092 0 SPLEN20048800 2.011 0 SPLEN20139360 79.641 0TESTI20063410 28.273 0 TESTI20150920 33.158 0 TRACH20026640 21.272 0UTERU20041970 0 72.886

TABLE 14 Clone ID UTERU TUTER ADRGL20020290 21.538 0 BRACE2003892010.185 0 BRAMY20091230 39.224 0 BRAMY20093490 62.465 0 BRAMY202278602.268 0 BRHIP20005060 61.644 0 CTONG20069320 18.336 0 CTONG2008343062.039 0 FCBBF30005360 41.409 0 FCBBF30257370 21.099 0 FEBRA200383305.808 0 FEBRA20039260 7.74 0 FEBRA20040260 43.146 0 FEBRA20078180 31.4470 FEBRA20087550 10.505 0 HLUNG20015070 9.042 0 HLUNG20015180 7.196 0MESAN20007110 50.674 0 MESAN20067430 20.114 0 MESAN20095800 14.162 0NT2RP70057500 14.698 0 SKMUS20008730 2.775 0 SKNMC20006350 1.084 0SMINT20035050 3.116 0 SMINT20045890 19.084 0 SPLEN20073880 30.142 0SPLEN20076470 17.567 0 SPLEN20118050 33.583 0 TESTI20030610 12.829 0TESTI20035330 9.688 0 TESTI20057590 9.042 0 TESTI20059080 9.096 0TESTI20105130 0 57.51 THYMU10004280 3.861 0 THYMU20139160 1.969 21.546UTERU10001060 31.804 0 UTERU10001870 100 0 UTERU20000230 34.999 0UTERU20000950 3.88 0 UTERU20011760 100 0 UTERU20013890 100 0UTERU20016580 22.164 0 UTERU20026620 33.752 0 UTERU20027360 100 0UTERU20029930 72.842 0 UTERU20031350 100 0 UTERU20035770 100 0UTERU20040150 100 0 UTERU20040370 6.264 0 UTERU20040390 100 0UTERU20040730 100 0 UTERU20041630 100 0 UTERU20041970 6.578 0UTERU20045200 62.039 0 UTERU20051790 100 0 UTERU20064120 100 0UTERU20065470 50.58 0 UTERU20079240 20.742 0 UTERU20083020 7.762 0UTERU20086530 100 0 UTERU20087070 100 0 UTERU20087850 100 0UTERU20089300 27.655 0 UTERU20089390 17.567 0 UTERU20089620 100 0UTERU20090940 100 0 UTERU20091470 100 0 UTERU20094830 100 0UTERU20095100 39.739 0 UTERU20099040 100 0 UTERU20099510 100 0UTERU20101150 100 0 UTERU20102260 24.918 0 UTERU20103040 100 0UTERU20103200 51.815 0 UTERU20104310 100 0 UTERU20106510 100 0UTERU20121140 100 0 UTERU20122520 51.33 0 UTERU20125810 100 0UTERU20127030 33.682 0 UTERU20127150 62.412 0 UTERU20128560 36.129 0UTERU20132620 51.94 0 UTERU20134830 100 0 UTERU20139760 100 0UTERU20140010 100 0 UTERU20167570 100 0 UTERU20168960 100 0UTERU20169020 100 0 UTERU20173030 100 0 UTERU20176230 72.842 0UTERU20177150 100 0 UTERU20181270 100 0 UTERU20185220 100 0UTERU20188670 100 0 UTERU20188840 40.303 0

TABLE 15 Clone ID NTONG CTONG ADRGL20023920 13.989 0 BRACE20038920 024.929 BRACE20050870 0 34.54 BRACE20061620 63.015 0 BRAMY20036530 21.2170 BRAMY20076130 0 6.434 BRAMY20204270 0 2.419 BRAMY20267780 0 4.633BRCAN10001680 14.71 0 CTONG10000090 0 87.752 CTONG20000340 0 100CTONG20002790 0 100 CTONG20004110 0 100 CTONG20004520 0 100CTONG20007660 0 100 CTONG20008190 0 100 CTONG20008460 0 100CTONG20015240 0 100 CTONG20017490 0 100 CTONG20020660 0 100CTONG20020950 0 100 CTONG20027660 0 49.358 CTONG20029030 0 44.292CTONG20030280 0 100 CTONG20031150 0 100 CTONG20031890 0 62.139CTONG20032930 0 29.763 CTONG20033500 0 100 CTONG20033610 0 57.263CTONG20033750 0 40.07 CTONG20035240 0 55.786 CTONG20036800 0 100CTONG20036990 0 100 CTONG20039370 0 40.07 CTONG20041150 0 100CTONG20041260 0 100 CTONG20042640 0 100 CTONG20044230 0 49.358CTONG20044870 0 74.685 CTONG20045500 0 40.07 CTONG20046690 0 100CTONG20049480 0 100 CTONG20050490 0 100 CTONG20051100 0 100CTONG20051450 0 100 CTONG20052780 0 100 CTONG20053990 0 100CTONG20055670 0 100 CTONG20055850 0 24.814 CTONG20056150 0 51.203CTONG20057750 0 100 CTONG20057950 0 54.423 CTONG20059130 0 72.445CTONG20060040 0 72.825 CTONG20061290 0 100 CTONG20062730 0 100CTONG20063770 0 62.139 CTONG20063930 0 28.37 CTONG20065240 0 100CTONG20065680 0 100 CTONG20066110 0 37.292 CTONG20068360 0 100CTONG20069320 0 11.22 CTONG20069420 0 42.813 CTONG20070090 0 100CTONG20070720 0 7.689 CTONG20070780 0 2.717 CTONG20070910 0 100CTONG20071040 0 32.374 CTONG20071680 0 49.582 CTONG20072930 0 100CTONG20073990 0 100 CTONG20074000 0 100 CTONG20074170 0 55.786CTONG20074740 0 100 CTONG20076230 0 100 CTONG20076810 0 100CTONG20077760 0 100 CTONG20078340 0 74.685 CTONG20079590 0 9.455CTONG20080140 0 27.673 CTONG20081840 0 100 CTONG20083430 0 37.961CTONG20083980 0 100 CTONG20084020 0 100 CTONG20084660 0 2.488CTONG20085210 0 27.762 CTONG20133720 18.528 46.879 CTONG20165590 0 100CTONG20165750 0 11.978 CTONG20166580 0 100 CTONG20167750 0 100CTONG20168240 37.367 11.818 CTONG20168460 0 23.709 CTONG20169040 0 100CTONG20169530 0 100 CTONG20170940 0 89.253 CTONG20174290 0 100CTONG20174580 0 100 CTONG20176040 0 100 CTONG20179390 0 100CTONG20179890 0 100 CTONG20179980 0 100 CTONG20180620 0 100CTONG20180690 0 100 CTONG20181350 0 100 CTONG20183430 0 55.786CTONG20183830 0 22.718 CTONG20184130 0 100 CTONG20184830 0 100CTONG20186140 0 100 CTONG20186290 0 38.33 CTONG20186370 0 39.387CTONG20186520 0 100 CTONG20186550 0 100 CTONG20188080 43.151 6.824CTONG20189000 0 100 CTONG20190290 0 100 CTONG20190630 0 100FCBBF20070950 0 14.977 FCBBF30001100 0 24.477 FCBBF30175350 32.34 10.228FCBBF40005000 0 20.766 FEBRA20027070 26.269 0 FEBRA20038330 0 3.554FEBRA20039260 7.487 0 FEBRA20040290 0 2.578 FEBRA20046200 0 16.309FEBRA20063720 0 8.106 FEBRA20078800 0 10.469 FEBRA20090220 0 12.173HCHON20000870 0 7.237 HLUNG20068120 25.03 0 MESAN20008150 0 38.598MESAN20027900 0 17.599 NT2NE20153620 0 39.142 NT2RP70001730 0 4.09NT2RP70012830 0 3.729 NT2RP70027790 0 39.806 NT2RP70057500 0 8.993NT2RP70064570 0 39.806 NT2RP70090870 35.801 0 NTONG20002230 50.815 0NTONG20005310 100 0 NTONG20017620 29.697 0 NTONG20029850 100 0NTONG20031580 100 0 NTONG20032100 100 0 NTONG20034540 67.622 0NTONG20035150 80.903 0 NTONG20043080 100 0 NTONG20048440 100 0NTONG20049180 63.818 20.184 NTONG20053630 100 0 NTONG20053730 100 0NTONG20053910 100 0 NTONG20055200 10.784 3.411 NTONG20058010 100 0NTONG20058220 100 0 OCBBF20110730 0 11.1 OCBBF20177540 0 16.869OCBBF20177910 0 22.909 PROST20016760 0 2.669 PROST20042700 0 33.088PROST20050390 0 30.175 PROST20063430 50.958 0 PROST20130320 0 11.979PUAEN10000650 7.056 0 PUAEN10001640 0 13.798 PUAEN20003120 0 19.799SKMUS20006790 5.155 0 SKNMC20006350 0 3.316 SKNSH20007160 0 9.506SMINT20030740 0 5.666 SMINT20035510 0 28.25 SMINT20089210 0 7.005SPLEN20024930 0 12.254 SPLEN20040780 0 20.5 SPLEN20063250 0 8.016SPLEN20181570 0 4.523 SPLEN20187490 0 23.141 TESTI20047370 0 1.998TESTI20057880 0 15.357 TESTI20064530 0 10.734 TESTI20079980 0 8.166TESTI20105130 0 4.825 TESTI20118460 63.366 0 TESTI20121040 0 17.698TESTI20197290 0 62.139 THYMU10004280 0 2.363 THYMU20030460 14.321 4.53THYMU20055460 0 10.818 THYMU20089900 0 37.939 THYMU20121040 0 54.423THYMU20139160 1.905 4.82 THYMU20145990 0 37.385 TRACH20011010 0 28.476TRACH20090060 0 6.234 UTERU20000230 0 21.416 UTERU20000950 0 2.374UTERU20016580 0 13.562 UTERU20045200 0 37.961 UTERU20083020 15.017 0

TABLE 16 Clone ID FCBBF FEBRA OCBBF BRACE BRALZ BRAMY BRAWH BRCAN BRCOCBRHIP BRSSN BRSTN BRTHA ADRGL- 0 0 0 0 0 12.942 0 0 0 0 0 0 0 20020290ADRGL- 0 0 0 0 0 21.897 0 0 0 22.674 0 0 0 20021910 ADRGL- 0 0 0 4.505 00 0 0 0 0 0 0 0 20023920 ADRGL- 8.812 35.914 0 0 0 0 0 0 0 0 0 0 020046760 ADRGL- 0 0 0 0 0 0 0 28.364 0 0 0 0 0 20062330 ADRGL-0 0 0 0 00 0 28.364 0 0 0 0 0 20079060 ASTRO- 0 0 0 0 0 0 21.998 0 0 0 0 0 020009140 ASTRO- 0 0 0 0 0 38.79 0 0 0 0 0 0 0 20020240 ASTRO- 0 0 25.9810 0 0 0 0 0 17.083 0 0 0 20027330 ASTRO- 0 0 0 0 0 0 0 0 0 0 0 49.891 020047510 ASTRO- 0 10.089 28.982 0 0 9.201 0 0 0 0 0 0 0 20055530 ASTRO-0 0 0 0 0 0 0 38.844 0 0 0 0 0 20055570 ASTRO- 31.867 0 0 0 0 0 0 0 0 00 0 0 20055930 ASTRO- 0 0 0 0 0 0 0 0 0 0 33.707 0 0 20090680 BGGI-4.804 0 0 0 0 0 0 0 0 0 0 0 0 120010750 BNGH- 0 0 0 10.084 0 0 0 0 0 0 00 0 420021680 BNGH- 0 0 0 0 0 0 0 0 0 0 0 0 52.181 420023870 BNGH- 8.8890 0 0 0 0 0 0 0 0 0 0 0 420059680 BNGH- 4.894 0 0 0 0 12.127 0 0 0 0 0 00 420074600 BNGH- 0 0 0 0 0 8.414 0 8.433 0 0 0 0 0 420086030 BRACE- 0 00 55.676 0 0 30.722 0 0 0 0 0 0 10000510 BRACE- 0 0 0 29.513 0 0 48.8560 0 0 0 0 0 20003310 BRACE- 0 0 0 38.94 0 0 0 0 0 0 61.06 0 0 20007330BRACE- 0 0 0 100 0 0 0 0 0 0 0 0 0 20009050 BRACE- 0 0 0 100 0 0 0 0 0 00 0 0 20014450 BRACE- 43.768 0 0 56.232 0 0 0 0 0 0 0 0 0 20017790BRACE- 0 0 0 100 0 0 0 0 0 0 0 0 0 20018810 BRACE- 0 0 0 50.035 0 0 0 00 49.965 0 0 0 20025820 BRACE- 0 20.132 9.638 6.346 0 12.24 0 0 0 0 0 00 20038920 BRACE- 6.844 0 26.708 8.793 0 0 0 0 0 0 0 0 0 20050870 BRACE-0 0 0 100 0 0 0 0 0 0 0 0 0 20051600 BRACE- 0 0 0 100 0 0 0 0 0 0 0 0 020051930 BRACE- 0 0 0 100 0 0 0 0 0 0 0 0 0 20052430 BRACE- 0 0 0 19.2370 0 0 0 0 0 0 0 80.763 20052530 BRACE- 0 0 0 26.402 0 0 0 25.519 026.365 0 0 0 20054080 BRACE- 0 0 0 40.468 0 0 0 0 0 0 0 0 0 20054480

TABLE 17 BRACE20054600 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20055560 0 0 0100 0 0 0 0 0 0 0 0 0 BRACE20057870 0 0 0 100 0 0 0 0 0 0 0 0 0BRACE20059110 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20059810 0 0 0 100 0 0 00 0 0 0 0 0 BRACE20061620 0 0 0 20.295 0 0 0 0 0 0 0 0 0 BRACE200625801.385 13.17 0 3.558 2.709 0 2.945 1.72 2.655 0 5.58 0 0 BRACE20063540 023.259 0 21.996 33.485 0 0 21.26 0 0 0 0 0 BRACE20065470 0 0 0 100 0 0 00 0 0 0 0 0 BRACE20066360 0 0 60.297 39.703 0 0 0 0 0 0 0 0 0BRACE20068710 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20069000 0 0 0 11.616 0 00 0 0 0 0 0 0 BRACE20069110 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20069440 00 0 100 0 0 0 0 0 0 0 0 0 BRACE20079200 0 0 0 100 0 0 0 0 0 0 0 0 0BRACE20079370 28.774 29.318 0 18.484 0 0 0 0 0 0 0 0 0 BRACE20097540 0 00 100 0 0 0 0 0 0 0 0 0 BRACE20098860 0 0 0 100 0 0 0 0 0 0 0 0 0BRACE20099070 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20194670 0 0 0 100 0 0 00 0 0 0 0 0 BRACE20196180 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20196960 0 00 100 0 0 0 0 0 0 0 0 0 BRACE20200770 0 0 0 100 0 0 0 0 0 0 0 0 0BRACE20200970 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20204670 0 0 0 6.427 0 00 0 0 0 0 0 0 BRACE20205840 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20207420 00 0 100 0 0 0 0 0 0 0 0 0 BRACE20212450 0 0 0 23.804 0 0 0 0 0 0 0 0 0BRACE20215410 0 0 0 26.992 0 26.03 0 0 0 0 0 0 0 BRACE20216700 0 0 0 1000 0 0 0 0 0 0 0 0 BRACE20216950 0 0 0 100 0 0 0 0 0 0 0 0 0BRACE20219360 0 0 0 40.506 0 0 0 0 0 0 0 0 0 BRAMY10000980 0 0 0 0 0 1000 0 0 0 0 0 0 BRAMY10001730 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20000210 00 0 0 0 100 0 0 0 0 0 0 0 BRAMY20000250 0 0 0 0 0 49.943 0 50.057 0 0 00 0 BRAMY20001510 0 0 0 0 2.866 1.815 3.116 0 0 0 0 0 0

TABLE 18 BRAMY20003540 4.956 0 0 3.184 0 3.07 10.541 6.155 0 9.538 04.824 0 BRAMY20003880 0 0 0 0 0 11.085 19.028 0 0 11.478 0 0 0BRAMY20005080 0 0 0 0 0 19.453 33.393 0 0 0 0 30.564 0 BRAMY20013670 0 00 0 0 100 0 0 0 0 0 0 0 BRAMY20016780 0 0 0 0 0 100 0 0 0 0 0 0 0BRAMY20020440 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20021580 0 0 0 0 0 100 00 0 0 0 0 0 BRAMY20023390 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20023640 0 00 0 0 100 0 0 0 0 0 0 0 BRAMY20024790 0 0 0 0 0 38.893 0 0 0 0 0 61.1070 BRAMY20027390 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20027990 0 0 0 0 0 1000 0 0 0 0 0 0 BRAMY20028530 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20028620 00 0 0 0 100 0 0 0 0 0 0 0 BRAMY20035380 0 0 0 0 0 100 0 0 0 0 0 0 0BRAMY20035830 9.114 0 0 0 0 22.586 0 0 0 0 0 0 0 BRAMY20036530 0 0 0 0 013.18 0 0 0 0 0 0 0 BRAMY20036810 0 0 0 0 0 61.711 0 0 0 0 0 0 0BRAMY20038980 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20039290 61.747 0 0 0 038.253 0 0 0 0 0 0 0 BRAMY20040580 0 0 0 0 0 100 0 0 0 0 0 0 0BRAMY20043520 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20043630 1.86 0 3.629 0 02.304 0 0 0 0 0 0 0 BRAMY20044920 0 0 0 0 0 100 0 0 0 0 0 0 0BRAMY20045210 0 0 0 0 0 29.335 0 0 0 0 0 0 0 BRAMY20045420 0 0 0 0 0 1000 0 0 0 0 0 0 BRAMY20047560 0 0 0 0 0 24.533 0 0 0 0 0 0 0 BRAMY200506400 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20050940 0 0 0 0 0 100 0 0 0 0 0 0 0BRAMY20051820 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20052440 0 0 0 0 0 53.9730 0 0 0 0 0 0 BRAMY20053910 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20055760 00 0 0 0 34.804 0 0 0 0 0 0 0 BRAMY20056620 0 0 0 0 0 100 0 0 0 0 0 0 0BRAMY20056840 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20063750 0 0 0 0 0 53.9730 0 0 0 0 0 0 BRAMY20072440 0 17.768 0 16.803 0 32.409 0 16.241 0 16.780 0 0

TABLE 19 BRAMY20072870 0 0 0 0 0 23.589 0 0 0 0 0 0 0 BRAMY20073080 0 00 0 0 100 0 0 0 0 0 0 0 BRAMY20074110 0 0 0 0 0 100 0 0 0 0 0 0 0BRAMY20074860 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20076100 0 0 0 0 0 100 00 0 0 0 0 0 BRAMY20076130 10.199 6.928 0 6.552 9.974 18.955 0 0 0 19.6280 9.927 0 BRAMY20076530 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20083330 0 0 00 0 100 0 0 0 0 0 0 0 BRAMY20083820 0 0 0 0 0 100 0 0 0 0 0 0 0BRAMY20089770 0 0 0 0 0 10.831 0 0 0 11.215 0 0 0 BRAMY20091230 0 0 0 037.206 23.57 0 0 0 0 0 0 0 BRAMY20093490 0 0 0 0 0 37.535 0 0 0 0 0 0 0BRAMY20094890 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20095080 0 0 0 0 0 49.0160 0 0 25.378 0 0 0 BRAMY20095570 0 0 0 0 0 49.128 0 0 0 50.872 0 0 0BRAMY20096930 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20100680 0 0 0 0 0 100 00 0 0 0 0 0 BRAMY20102900 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20107980 0 00 0 0 100 0 0 0 0 0 0 0 BRAMY20111780 0 0 0 0 0 100 0 0 0 0 0 0 0BRAMY20117670 11.164 0 0 14.344 0 6.916 0 0 0 0 33.738 10.866 0BRAMY20118410 0 0 0 0 0 49.128 0 0 0 50.872 0 0 0 BRAMY20118490 0 0 0 00 49.128 0 0 0 50.872 0 0 0 BRAMY20120170 0 0 0 0 0 100 0 0 0 0 0 0 0BRAMY20123400 0 0 0 0 0 49.128 0 0 0 50.872 0 0 0 BRAMY20124970 0 0 0 00 100 0 0 0 0 0 0 0 BRAMY20125170 0 52.301 0 0 0 47.699 0 0 0 0 0 0 0BRAMY20125360 0 0 0 0 0 17.442 0 17.481 26.994 0 0 0 0 BRAMY20125550 0 00 0 0 100 0 0 0 0 0 0 0 BRAMY20126910 0 0 0 0 0 100 0 0 0 0 0 0 0BRAMY20127310 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20127760 0 0 0 0 0 100 00 0 0 0 0 0 BRAMY20134050 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20135720 0 00 0 0 100 0 0 0 0 0 0 0 BRAMY20137360 0 0 0 0 0 100 0 0 0 0 0 0 0BRAMY20139440 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20139750 0 0 0 0 0 100 00 0 0 0 0 0

TABLE 20 BRAMY20143870 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20152510 17.7030 0 0 0 21.934 37.651 0 0 22.713 0 0 0 BRAMY20155500 0 0 0 0 0 53.973 00 0 0 0 0 0 BRAMY20158550 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20159250 0 00 0 0 100 0 0 0 0 0 0 0 BRAMY20160020 0 0 0 0 0 100 0 0 0 0 0 0 0BRAMY20173480 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20190550 0 0 0 0 0 5.2780 5.289 0 5.465 8.581 8.292 0 BRAMY20194680 0 0 0 0 0 100 0 0 0 0 0 0 0BRAMY20204270 0 2.605 0 0 3.75 4.752 4.078 2.381 0 2.46 0 7.465 0BRAMY20206340 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20219620 0 0 0 0 0 100 00 0 0 0 0 0 BRAMY20221600 0 0 0 0 0 53.973 0 0 0 0 0 0 0 BRAMY20223010 00 0 0 0 100 0 0 0 0 0 0 0 BRAMY20225250 0 0 0 0 0 100 0 0 0 0 0 0 0BRAMY20225320 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20227230 0 0 0 0 0 100 00 0 0 0 0 0 BRAMY20227860 1.466 1.494 0.715 1.884 2.151 8.177 6.2385.919 4.218 9.408 2.216 0 1.978 BRAMY20227960 44.662 0 0 0 0 55.338 0 00 0 0 0 0 BRAMY20231150 0 0 0 0 0 49.128 0 0 0 50.872 0 0 0BRAMY20234820 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20237190 0 0 0 0 0 19.8270 0 0 0 0 0 0 BRAMY20238630 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20243120 00 0 0 0 100 0 0 0 0 0 0 0 BRAMY20244490 0 0 0 0 0 100 0 0 0 0 0 0 0BRAMY20245140 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20245350 0 0 0 0 0 100 00 0 0 0 0 0 BRAMY20245760 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20251210 0 00 0 0 49.943 0 50.057 0 0 0 0 0 BRAMY20251750 0 0 0 0 0 100 0 0 0 0 0 00 BRAMY20263000 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20267780 1.836 0 0 0 02.275 0 0 0 0 0 0 0 BRAMY20269040 0 0 0 0 0 100 0 0 0 0 0 0 0BRAMY20271140 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20274510 0 0 0 0 0 100 00 0 0 0 0 0 BRAMY20285650 0 0 0 0 0 61.711 0 0 0 0 0 0 0 BRAMY20287400 00 0 0 0 100 0 0 0 0 0 0 0

TABLE 21 BRAWH20014590 0 0 0 0 0 0 43.087 0 0 12.996 20.407 0 0BRAWH20020470 0 0 0 37.659 0 0 62.341 0 0 0 0 0 0 BRAWH20020600 0 0 0 00 0 100 0 0 0 0 0 0 BRAWH20021910 0 0 0 0 0 0 100 0 0 0 0 0 0BRAWH20025490 0 0 0 0 0 0 52.588 0 47.412 0 0 0 0 BRAWH20026010 0 0 0 00 0 27.777 16.218 0 0 0 0 0 BRAWH20027250 0 0 0 0 0 0 24.306 0 0 0 0 0 0BRAWH20030000 0 0 0 0 0 0 100 0 0 0 0 0 0 BRAWH20039640 0 0 0 0 0 0 1000 0 0 0 0 0 BRAWH20040680 0 0 0 0 0 0 100 0 0 0 0 0 0 BRAWH20047790 0 00 0 0 0 100 0 0 0 0 0 0 BRAWH20050740 31.981 0 0 0 0 0 68.019 0 0 0 0 00 BRAWH20055240 0 0 0 0 0 0 100 0 0 0 0 0 0 BRAWH20055330 0 0 0 0 0 0100 0 0 0 0 0 0 BRAWH20055780 0 0 0 0 0 0 45.321 0 0 54.679 0 0 0BRAWH20058120 0 0 0 0 0 0 100 0 0 0 0 0 0 BRAWH20063010 0 0 0 0 0 0 1000 0 0 0 0 0 BRAWH20078080 0 0 0 0 0 0 100 0 0 0 0 0 0 BRAWH20078620 0 00 0 0 0 100 0 0 0 0 0 0 BRAWH20080580 0 0 47.847 0 0 0 52.153 0 0 0 0 00 BRAWH20082550 4.964 0 9.686 0 0 6.151 10.558 0 0 0 0 0 0 BRAWH200829200 0 0 0 0 0 69.313 0 0 0 0 0 0 BRAWH20093040 0 0 0 0 0 0 29.619 0 26.7040 0 0 0 BRAWH20093070 0 0 0 24.51 0 0 27.05 0 0 8.159 0 0 0BRAWH20094900 0 0 0 37.659 0 0 62.341 0 0 0 0 0 0 BRAWH20095900 0 0 0 00 36.811 63.189 0 0 0 0 0 0 BRAWH20173790 0 0 0 0 0 23.285 39.971 0 0 00 0 0 BRAWH20174330 0 0 0 0 0 0 100 0 0 0 0 0 0 BRAWH20175230 0 0 0 0 00 100 0 0 0 0 0 0 BRAWH20175340 0 0 0 0 0 0 100 0 0 0 0 0 0BRAWH20176850 0 0 29.749 0 0 18.89 32.427 18.933 0 0 0 0 0 BRAWH201826700 0 0 0 0 0 100 0 0 0 0 0 0 BRAWH20183170 0 0 0 0 0 0 100 0 0 0 0 0 0BRAWH20185260 0 0 0 0 0 36.811 63.189 0 0 0 0 0 0 BRAWH20185270 0 0 0 00 0 35.8 0 0 0 0 0 0 BRAWH20186010 0 0 0 0 0 0 100 0 0 0 0 0 0BRAWH20188750 0 0 0 0 0 0 100 0 0 0 0 0 0

TABLE 22 BRAWH20190530 0 0 0 0 0 0 100 0 0 0 0 0 0 BRAWH20190550 0 0 0 00 0 100 0 0 0 0 0 0 BRAWH20191980 0 0 0 37.659 0 0 62.341 0 0 0 0 0 0BRCAN10000760 0 0 0 0 0 0 0 6.922 0 0 0 0 0 BRCAN10001050 0 0 0 0 0 0 0100 0 0 0 0 0 BRCAN10001680 0 5.009 0 0 0 9.137 0 13.737 0 14.193 014.356 0 BRCAN20001480 0 0 0 0 0 0 0 100 0 0 0 0 0 BRCAN20004180 0 0 0 00 0 0 100 0 0 0 0 0 BRCAN20005230 0 0 0 0 0 0 0 100 0 0 0 0 0BRCAN20005410 0 0 0 0 0 0 0 100 0 0 0 0 0 BRCOC10000400 0 0 0 0 0 0 0 059.913 40.087 0 0 0 BRCOC20000470 0 0 0 0 50.495 0 0 0 49.505 0 0 0 0BRCOC20003600 0 0 0 0 0 0 39.923 0 35.994 24.083 0 0 0 BRHIF10000720 0 00 0 0 0 0 0 0 100 0 0 0 BRHIP10001040 1.184 1.608 0 0 6.947 7.335 12.59113.233 13.622 10.633 7.156 4.61 0 BRHIP20000210 0 0 0 0 0 0 0 0 0 100 00 0 BRHIP20003590 0 0 0 0 0 0 0 0 0 100 0 0 0 BRHIP20005060 0 0 0 0 0 00 0 0 38.356 0 0 0 BRSSN20001970 0 0 0 0 0 0 0 0 0 0 100 0 0BRSSN20005610 23.474 15.945 0 0 0 14.542 0 0 0 0 23.646 0 0BRSSN20005660 0 34.081 0 16.116 24.533 0 0 0 0 0 25.27 0 0 BRSSN200664400 0 0 0 0 0 0 0 0 0 100 0 0 BRSSN20074640 0 0 0 0 0 0 0 0 48.765 051.235 0 0 BRSSN20091190 0 0 0 0 0 0 0 0 0 0 68.148 0 0 BRSSN20092440 00 0 0 0 0 0 0 0 0 34.564 0 0 BRSSN20093890 0 0 0 0 0 0 0 0 0 0 100 0 0CTONG20032930 0 32.048 0 0 0 0 0 0 0 0 0 0 0 CTONG20035240 44.214 0 0 00 0 0 0 0 0 0 0 0 CTONG20044870 0 0 0 0 0 0 0 0 0 25.315 0 0 0CTONG20063930 0 0 0 0 0 27.859 0 0 0 0 0 43.771 0 CTONG20069320 0 0 05.712 0 5.509 0 0 0 0 0 0 0 CTONG20070720 0 0 0 0 11.919 0 0 7.568 0 012.278 0 0 CTONG20071040 0 0 0 0 0 0 0 15.932 0 0 51.694 0 0CTONG20071680 0 0 0 0 0 0 0 0 0 50.418 0 0 0 CTONG20074170 44.214 0 0 00 0 0 0 0 0 0 0 0 CTONG20078340 0 0 0 0 0 0 0 0 0 25.315 0 0 0CTONG20079590 0 0 0 0 14.657 0 0 0 0 0 15.097 0 0

TABLE 23 CTONG20080140 0 0 0 0 0 0 0 0 0 28.14 44.187 0 0 CTONG2008521044.007 0 0 0 0 0 0 0 0 28.231 0 0 0 CTONG20133720 0 0 0 0 0 5.755 0 0 05.959 0 0 0 CTONG20165750 23.734 0 18.524 0 0 0 0 0 0 0 0 0 0CTONG20168240 18.734 0 0 0 0 0 0 0 0 0 0 0 0 CTONG20170940 0 0 0 0 0 010.747 0 0 0 0 0 0 CTONG20183430 44.214 0 0 0 0 0 0 0 0 0 0 0 0CTONG20186370 31.217 0 0 0 0 0 0 0 0 0 0 0 0 CTONG20188080 0 0 0 0 06.701 0 0 10.371 13.878 0 0 0 FCBBF10000230 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF10002200 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF10004760 100 0 0 0 0 0 00 0 0 0 0 0 FCBBF20018680 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF20020440 1000 0 0 0 0 0 0 0 0 0 0 0 FCBBF20021110 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF20023490 3.866 10.504 0 0 0 0 0 0 7.413 4.96 0 7.525 0FCBBF20028980 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF20029280 43.802 0 0 0 0 00 0 0 56.198 0 0 0 FCBBF20032930 33.937 0 0 0 0 0 0 0 0 0 0 66.063 0FCBBF20033360 23.246 0 22.679 0 0 4.8 0 0 7.429 4.971 0 0 0FCBBF20035430 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF20035490 19.559 0 0 0 0 00 0 0 0 0 0 0 FCBBF20036360 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF20038230100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF20038950 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF20041380 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF20043730 100 0 0 0 0 0 00 0 0 0 0 0 FCBBF20054390 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF2005658033.254 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF20059660 33.765 0 0 0 0 0 0 0 0 0 00 0 FCBBF20061310 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF20066340 10.481 0 0 00 0 0 13.016 0 0 0 0 0 FCBBF20070800 9.281 12.609 0 0 0 11.5 19.74123.052 0 23.817 0 0 0 FCBBF20070950 11.871 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30000010 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30001020 100 0 0 0 0 0 00 0 0 0 0 0 FCBBF30001100 19.4 0 37.855 0 0 0 0 0 0 0 0 0 0

TABLE 24 FCBBF30001150 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30002270 20.7730 0 0 0 0 0 0 0 0 0 0 0 FCBBF30002280 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30002330 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30003610 100 0 0 0 0 0 00 0 0 0 0 0 FCBBF30004340 8.95 0 8.731 17.248 8.752 5.544 0 11.114 011.482 9.015 0 0 FCBBF30004730 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30005180100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30005360 20.082 0 0 0 0 0 0 0 38.509 00 0 0 FCBBF30005500 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30019140 100 0 0 00 0 0 0 0 0 0 0 0 FCBBF30019180 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30019240 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30021900 100 0 0 0 0 0 00 0 0 0 0 0 FCBBF30022680 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF3002658042.399 57.601 0 0 0 0 0 0 0 0 0 0 0 FCBBF30029250 28.042 0 0 0 0 0 0 0 071.958 0 0 0 FCBBF30035570 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30042610 1000 0 0 0 0 0 0 0 0 0 0 0 FCBBF30048420 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30053300 3.746 2.544 0 0 0 0 0 2.326 0 0 0 0 0 FCBBF30056980 34.2510 0 0 0 0 0 0 0 0 0 0 0 FCBBF30062490 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30063990 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30068210 100 0 0 0 0 0 00 0 0 0 0 0 FCBBF30071500 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF3007244036.866 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30072480 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30074530 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30074620 100 0 0 0 0 0 00 0 0 0 0 0 FCBBF30075970 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30076310 1000 0 0 0 0 0 0 0 0 0 0 0 FCBBF30078600 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30079770 42.399 57.601 0 0 0 0 0 0 0 0 0 0 0 FCBBF30080730 34.275 00 0 0 0 0 0 65.725 0 0 0 0 FCBBF30081000 20.379 0 39.764 0 39.858 0 0 00 0 0 0 0 FCBBF30085560 100 0 0 0 0 0 0 0 0 0 0 0 0

TABLE 25 FCBBF30088700 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30089380 51.5030 0 0 0 0 0 0 0 0 0 0 0 FCBBF30091010 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30091520 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30093170 72.234 0 0 0 0 00 0 0 0 0 0 0 FCBBF30095410 20.765 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30099490100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30100080 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30100120 30.645 11.895 25.627 0 8.563 0 9.311 5.437 0 0 0 8.522 0FCBBF30100410 56.537 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30101240 100 0 0 0 0 00 0 0 0 0 0 0 FCBBF30101300 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30105080100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30105440 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30105860 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30106950 30.112 0 0 0 0 00 0 0 0 0 0 0 FCBBF30107290 56.537 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30107330100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30114180 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30114850 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30115230 30.112 0 0 0 0 00 0 0 0 0 0 0 FCBBF30115920 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30118670100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30118890 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30125460 4.752 6.455 9.271 0 0 17.662 0 5.901 0 12.193 0 0 0FCBBF30125880 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30128420 100 0 0 0 0 0 00 0 0 0 0 0 FCBBF30129010 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30130410 1000 0 0 0 0 0 0 0 0 0 0 0 FCBBF30130580 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30132050 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30132660 100 0 0 0 0 0 00 0 0 0 0 0 FCBBF30135890 34.566 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30136230100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30138000 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30142290 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30143550 100 0 0 0 0 0 00 0 0 0 0 0

TABLE 26 FCBBF30145670 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30151190 100 0 00 0 0 0 0 0 0 0 0 0 FCBBF30153170 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30157270 56.537 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30161780 100 0 0 0 0 00 0 0 0 0 0 0 FCBBF30164510 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30166220100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30169280 16.742 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30169870 43.802 0 0 0 0 0 0 0 0 56.198 0 0 0 FCBBF30170710 100 0 00 0 0 0 0 0 0 0 0 0 FCBBF30171230 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30172330 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30173960 56.537 0 0 0 0 00 0 0 0 0 0 0 FCBBF30175350 8.107 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30177290100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30179180 43.582 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30179740 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30181730 100 0 0 0 0 0 00 0 0 0 0 0 FCBBF30194370 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30194550 1000 0 0 0 0 0 0 0 0 0 0 0 FCBBF30195690 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30195700 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30197840 100 0 0 0 0 0 00 0 0 0 0 0 FCBBF30198670 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30201630 1000 0 0 0 0 0 0 0 0 0 0 0 FCBBF30212210 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30215240 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30220050 100 0 0 0 0 0 00 0 0 0 0 0 FCBBF30222910 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30223110 1000 0 0 0 0 0 0 0 0 0 0 0 FCBBF30223210 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30225930 21.93 0 0 0 0 27.172 0 0 0 0 0 0 0 FCBBF30228940 51.503 00 0 0 0 0 0 0 0 0 0 0 FCBBF30230610 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30236670 0.694 2.83 0 0.892 1.358 0 0 2.586 0 0.891 2.797 0 3.745FCBBF30250980 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30255680 100 0 0 0 0 0 00 0 0 0 0 0

TABLE 27 FCBBF30257370 15.348 13.901 0 0 0 0 0 0 0 0 0 9.959 0FCBBF30259050 43.768 0 0 56.232 0 0 0 0 0 0 0 0 0 FCBBF30260210 100 0 00 0 0 0 0 0 0 0 0 0 FCBBF30260480 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30263080 23.584 0 0 0 0 0 0 29.288 0 0 0 0 0 FCBBF30266510 56.537 00 0 0 0 0 0 0 0 0 0 0 FCBBF30271990 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF30275590 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30282020 46.286 0 0 0 0 00 0 0 0 0 0 0 FCBBF30285930 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30287940100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF40000610 100 0 0 0 0 0 0 0 0 0 0 0 0FCBBF40001920 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF40005000 16.459 0 0 0 0 00 0 0 0 0 0 0 FCBBF50000410 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF5000061043.582 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF50001650 33.921 15.361 0 14.527 014.01 0 0 0 0 0 0 0 FCBBF50003530 44.606 0 0 0 0 0 0 55.394 0 0 0 0 0FCBBF50004950 100 0 0 0 0 0 0 0 0 0 0 0 0 FEBRA20005040 0 100 0 0 0 0 00 0 0 0 0 0 FEBRA20007820 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA2001867027.69 18.809 0 0 0 0 0 0 26.549 0 0 26.952 0 FEBRA20026820 0 100 0 0 0 00 0 0 0 0 0 0 FEBRA20027070 0 8.946 0 0 0 0 0 0 0 0 0 0 0 FEBRA200296200 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20031000 23.203 31.522 45.275 0 0 0 0 00 0 0 0 0 FEBRA20031150 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20031280 058.203 41.797 0 0 0 0 0 0 0 0 0 0 FEBRA20031810 0 100 0 0 0 0 0 0 0 0 00 0 FEBRA20035200 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20035240 0 100 0 0 00 0 0 0 0 0 0 0 FEBRA20038220 0 22.453 0 0 0 0 0 0 0 0 0 0 0FEBRA20038330 5.634 15.308 5.497 0 0 6.981 0 0 5.402 0 0 0 15.195FEBRA20038970 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20039070 0 100 0 0 0 0 00 0 0 0 0 0 FEBRA20039260 0 2.55 0 2.411 0 2.325 0 0 3.599 2.408 0 3.6540 FEBRA20040230 0 63.862 0 0 0 0 0 0 0 0 0 0 0

TABLE 28 FEBRA20040260 0 56.854 0 0 0 0 0 0 0 0 0 0 0 FEBRA200402902.043 2.776 0 0 7.992 2.531 0 5.074 0 0 0 0 11.021 FEBRA20040560 059.062 0 0 0 0 0 0 0 0 0 0 0 FEBRA20045380 0 100 0 0 0 0 0 0 0 0 0 0 0FEBRA20046200 0 17.561 0 0 0 0 0 0 0 0 0 0 0 FEBRA20046280 0 100 0 0 0 00 0 0 0 0 0 0 FEBRA20046510 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20057010 0100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20063720 0 34.914 12.537 0 0 0 0 0 0 0 00 0 FEBRA20076200 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20078180 0 20.719 0 00 0 0 0 0 0 0 0 0 FEBRA20078800 0 22.544 0 0 0 0 0 0 0 0 0 0 0FEBRA20080860 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20082660 0 22.641 0 0 0 00 0 0 0 0 0 0 FEBRA20083410 0 14.361 0 0 0 0 0 0 0 0 0 0 0 FEBRA200847500 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20086600 0 100 0 0 0 0 0 0 0 0 0 0 0FEBRA20087550 0 6.921 0 0 0 0 0 0 9.769 0 0 0 0 FEBRA20088610 24.12232.771 15.689 0 0 0 17.101 0 0 10.316 0 0 0 FEBRA20088810 0 100 0 0 0 00 0 0 0 0 0 0 FEBRA20090160 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20090220 06.554 2.353 0 2.359 0 2.565 0 6.938 0 2.43 0 0 FEBRA20091620 0 100 0 0 00 0 0 0 0 0 0 0 FEBRA20092760 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA200932700 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20093280 0 100 0 0 0 0 0 0 0 0 0 0 0FEBRA20095410 0 59.062 0 0 0 0 0 0 0 0 0 0 0 FEBRA20098040 13.01 35.3490 0 0 0 0 0 24.947 16.692 0 0 0 FEBRA20099860 0 34.616 0 0 0 0 0 0 065.384 0 0 0 FEBRA20101410 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20108020 0100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20108580 8.812 35.914 0 0 0 0 0 0 0 0 0 00 FEBRA20115930 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20116650 18.022 24.48435.165 0 0 22.329 0 0 0 0 0 0 0 FEBRA20121200 0 36.922 0 0 0 0 0 0 0 0 00 0 FEBRA20121950 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20141980 0 100 0 0 00 0 0 0 0 0 0 0

TABLE 29 FEBRA20150420 0 34.905 0 0 0 31.834 0 0 0 0 0 0 0 FEBRA201517500 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20163980 9.44 12.825 0 0 0 0 0 0 0 0 00 0 FEBRA20170240 0 36.922 0 0 0 0 0 0 0 0 0 0 0 FEBRA20172230 0 100 0 00 0 0 0 0 0 0 0 0 FEBRA20173330 0 100 0 0 0 0 0 0 0 0 0 0 0FEBRA20175020 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20175330 0 100 0 0 0 0 00 0 0 0 0 0 FEBRA20177800 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20180510 0100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20182030 42.399 57.601 0 0 0 0 0 0 0 0 00 0 FEBRA20187460 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20191720 0 100 0 0 00 0 0 0 0 0 0 0 HCHON20002650 0 0 0 19.66 0 0 0 0 0 0 0 0 0HCHON20002710 13.027 17.697 0 0 0 0 0 0 0 0 0 0 0 HEART10001490 3.58 06.986 0 0 0 0 0 0 0 0 0 0 HLUNG20008460 0 0 32.46 0 0 0 0 0 0 0 0 0 0HLUNG20011460 0 0 0 0 0 0 0 23.423 0 0 0 0 0 HLUNG20014590 0 0 0 0 0 0 011.025 0 0 0 0 0 HLUNG20015070 0 0 0 0 0 5.433 0 0 8.409 0 0 0 0HLUNG20015180 0 3.161 0 0 0 0 0 0 0 0 4.688 0 0 HLUNG20020850 0 0 0 032.512 0 0 0 0 0 0 0 0 HLUNG20028110 0 0 0 0 0 23.382 0 0 0 0 0 0 0HLUNG20031620 19.763 0 0 0 0 0 0 0 0 0 0 0 0 HLUNG20032460 0 0 0 021.215 0 0 13.47 0 0 0 0 0 HLUNG20033060 0 0 17.556 0 0 0 0 0 0 11.544 00 0 HLUNG20041590 2.514 3.415 0 0 0 3.115 0 3.122 0 0 0 0 0HLUNG20045340 0 0 0 0 0 0 0 0 0 2.424 0 0 0 HLUNG20056560 0 0 0 24.039 00 0 0 0 0 0 0 0 HLUNG20068120 6.274 0 0 0 0 0 0 0 0 0 0 0 0HLUNG20081390 0 0 0 0 0 0 0 0 0 20.993 0 0 0 HLUNG20083480 3.232 012.614 4.153 0 4.005 0 0 6.198 4.147 0 0 0 HLUNG20085210 0 0 0 0 0 0 0 00 0 0 24.45 0 HLUNG20094130 0 0 0 0 0 0 0 0 0 24.013 0 0 0 KIDNE200806900 0 0 7.981 24.298 11.545 0 3.857 17.867 3.985 12.514 12.092 0KIDNE20084030 0 0 0 0 0 26.283 0 0 0 13.608 0 0 0 KIDNE20086660 0 0 0 00 0 52.987 0 0 0 0 0 0

TABLE 30 KIDNE20094670 0 0 0 40.506 0 0 0 0 0 0 0 0 0 KIDNE2013413034.637 0 0 0 0 0 0 0 0 0 0 0 0 KIDNE20138450 20.652 0 0 0 0 0 0 0 0 0 00 0 KIDNE20140870 12.151 0 0 0 0 0 0 0 23.3 0 0 0 0 KIDNE20149780 0 0 00 0 39.635 0 0 0 0 0 0 0 KIDNE20170400 0 0 0 0 0 0 0 0 0 13.296 0 0 0KIDNE20173430 0 0 0 0 0 0 0 0 0 0 0 0 26.207 MESAN20021860 0 5.216 0 0 00 0 0 0 0 0 7.474 0 MESAN20030350 19.943 0 0 0 0 0 0 0 0 0 0 0 0MESAN20034440 0 0 0 0 0 0 0 0 0 0 0 19.81 0 MESAN20038520 4.894 0 0 0 012.127 0 0 0 0 0 0 0 MESAN20045750 0 0 0 0 0 0 0 0 48.859 0 0 0 0MESAN20067430 0 0 0 0 0 0 0 0 0 0 0 0 26.308 MESAN20089260 24.608 0 0 00 0 0 0 0 0 0 0 0 MESAN20095800 0 0 0 0 0 0 0 8.529 0 8.812 13.837 0 0NT2NE20026200 0 0 0 0 1.22 11.547 1.328 0.775 1.197 0 0 3.646 0NT2NE20033150 0 0 49.867 0 0 0 0 0 0 0 0 0 0 NT2NE20042550 0 40.917 0 00 0 0 0 0 0 0 0 0 NT2NE20045190 7.802 0 7.612 0 0 4.834 0 0 0 0 7.86 021.043 NT2NE20053950 21.964 0 21.429 14.11 0 0 0 0 0 0 0 0 0NT2NE20061030 20.536 0 0 0 0 0 0 0 0 0 0 0 0 NT2NE20069580 0 40.917 0 00 0 0 0 0 0 0 0 0 NT2NE20082130 0 0 0 0 0 0 0 24.112 0 0 0 37.798 0NT2NE20082600 33.765 0 0 0 0 0 0 0 0 0 0 0 0 NT2NE20088030 0 0 0 39.5750 0 0 0 0 0 0 0 0 NT2NE20092950 0 14.453 0 0 0 0 0 0 0 13.65 0 20.71 0NT2NE20095230 0 0 0 0 0 17.429 0 0 0 0 0 27.383 0 NT2NE20108420 23.14731.446 0 0 0 0 0 0 0 0 0 0 0 NT2NE20111190 0 0 0 0 0 38.711 0 0 0 0 0 00 NT2NE20112210 0 0 0 0 0 0 0 0 0 0 0 0 73.331 NT2NE20141040 0 24.941 00 0 0 39.046 0 0 0 0 0 0 NT2NE20177210 0 0 0 28.643 0 27.623 0 0 0 0 0 00 NT2NE20181800 23.559 0 0 0 0 0 0 0 0 30.226 0 0 0 NT2RI20021200 0 0 00 0 4.233 7.265 8.484 6.55 35.063 6.882 6.65 0 NT2RP70001120 0 0 33.3120 0 0 0 0 0 0 0 0 0 NT2RP70001730 22.691 8.808 31.625 0 0 0 0 0 3.108 03.265 0 0 NT2RP70012830 0 0 11.535 0 0 0 0 0 5.668 0 0 11.508 0

TABLE 31 NT2RP70035110 12.287 0 0 0 0 0 0 0 0 0 0 0 0 NT2RP700575007.128 0 13.909 0 0 0 0 0 0 0 0 0 0 NT2RP70075300 3.525 0 3.439 2.264 02.184 0 0 0 0 0 0 0 NT2RP70087140 3.902 10.602 0 10.026 0 24.172 0 0 0 00 0 21.047 NT2RP70090870 17.949 0 17.511 0 0 0 0 0 0 0 0 0 0NTONG20002230 0 0 24.855 0 0 0 0 0 0 0 0 0 0 NTONG20017620 22.333 014.526 0 0 18.447 0 0 0 0 14.998 0 0 NTONG20049180 15.998 0 0 0 0 0 0 00 0 0 0 0 NTONG20055200 0 0 0 0 0 0 0 3.357 10.367 10.405 0 0 14.581OCBBF20000740 30.257 10.276 44.279 0 0 9.372 0 0 0 0 0 0 0 OCBBF200017800 0 23.138 15.235 23.193 0 0 0 0 0 0 23.084 0 OCBBF20005220 0 0 67.45 00 0 0 0 0 0 0 0 0 OCBBF20009820 0 0 10.495 0 0 0 0 0 5.157 0 0 0 0OCBBF20011860 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20012520 0 0 100 0 0 0 00 0 0 0 0 0 OCBBF20016390 10.001 13.586 19.514 0 0 0 21.27 12.419 0 0 00 0 OCBBF20016810 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20109450 0 0 100 0 00 0 0 0 0 0 0 0 OCBBF20109780 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF2011021023.865 0 46.566 0 0 29.569 0 0 0 0 0 0 0 OCBBF20110730 0 35.856 34.333 00 0 18.711 0 0 0 0 0 0 OCBBF20111370 0 0 100 0 0 0 0 0 0 0 0 0 0OCBBF20111600 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20112280 0 0 100 0 0 0 00 0 0 0 0 0 OCBBF20112320 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20113110 0 0100 0 0 0 0 0 0 0 0 0 0 OCBBF20115360 7.945 10.793 31.004 10.207 0 9.8430 9.866 0 0 0 0 0 OCBBF20116250 0 41.046 58.954 0 0 0 0 0 0 0 0 0 0OCBBF20117220 15.972 21.698 62.33 0 0 0 0 0 0 0 0 0 0 OCBBF20118720 0 0100 0 0 0 0 0 0 0 0 0 0 OCBBF20119810 0 0 100 0 0 0 0 0 0 0 0 0 0OCBBF20120010 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20120950 0 0 100 0 0 0 00 0 0 0 0 0 OCBBF20121910 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20123200 0 0100 0 0 0 0 0 0 0 0 0 0 OCBBF20142290 0 5.048 21.749 0 0 4.603 0 0 014.301 0 0 20.041 OCBBF20147070 0 0 100 0 0 0 0 0 0 0 0 0 0

TABLE 32 OCBBF20152330 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20155030 0 050.561 0 0 0 0 0 0 0 0 0 0 OCBBF20156450 0 0 100 0 0 0 0 0 0 0 0 0 0OCBBF20157970 0 0 71.737 0 0 0 0 0 0 0 0 0 0 OCBBF20160380 0 0 100 0 0 00 0 0 0 0 0 0 OCBBF20165900 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20165910 00 100 0 0 0 0 0 0 0 0 0 0 OCBBF20166890 0 0 33.861 0 0 0 0 0 0 0 0 0 0OCBBF20166900 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20167290 0 0 19.457 0 037.065 0 0 0 0 0 0 0 OCBBF20170350 7.839 10.65 30.593 0 15.332 0 0 9.7350 10.058 15.793 0 0 OCBBF20174580 25.726 0 25.099 0 0 0 0 0 0 0 0 0 0OCBBF20174890 0 0 33.338 0 0 0 0 0 0 0 34.421 0 0 OCBBF20175360 10.644 020.77 0 0 0 0 0 0 0 0 0 0 OCBBF20176650 0 0 100 0 0 0 0 0 0 0 0 0 0OCBBF20177540 13.37 18.164 26.088 0 0 0 0 0 0 0 0 0 0 OCBBF2017791018.157 0 35.429 0 0 0 0 0 0 0 0 0 0 OCBBF20182060 0 0 100 0 0 0 0 0 0 00 0 0 OCBBF20185630 0 0 71.737 0 0 0 0 0 0 0 0 0 0 OCBBF20188280 0 0 1000 0 0 0 0 0 0 0 0 0 OCBBF20191950 0 0 100 0 0 0 0 0 0 0 0 0 0PLACE60054820 0 0 0 0 0 0 0 19.271 0 0 31.264 0 0 PLACE60056910 0 0 0 00 39.559 0 0 0 0 0 0 0 PLACE60061370 0 0 0 0 18.524 11.735 0 11.761 0 00 0 0 PLACE60064740 0 0 0 0 0 39.559 0 0 0 0 0 0 0 PLACE60073090 0 0 07.15 0 0 0 0 0 0 0 0 0 PLACE60120280 0 0 0 0 0 15.655 0 0 0 0 0 0 0PLACE60132200 0 0 0 0 0 0 0 0 22.765 0 0 0 0 PLACE60150510 33.854 0 0 00 0 0 0 0 0 34.102 0 0 PLACE60154450 0 0 0 0 33.747 0 0 0 0 0 0 33.589 0PLACE60157310 0 0 0 0 0 0 0 0 66.952 0 0 0 0 PLACE60162100 0 26.059 0 00 0 0 0 0 0 0 0 0 PROST10002150 10.939 0 0 14.054 0 0 0 0 0 0 0 0 0PROST20014150 0 0 67.029 0 0 0 0 0 0 0 0 0 0 PROST20016760 2.116 2.874 05.436 0 5.243 4.5 0 0 2.714 0 4.118 0 PROST20024250 0 0 32.244 0 020.475 0 0 0 0 0 0 0 PROST20035170 0 0 11.544 0 0 0 0 0 0 0 0 0 0

TABLE 33 PROST20035830 34.251 0 0 0 0 0 0 0 0 0 0 0 0 PROST2004270013.112 0 0 0 0 0 0 16.283 0 0 0 0 0 PROST20045700 11.365 0 0 0 22.229 00 0 0 0 0 0 0 PROST20050390 23.916 0 0 0 0 0 0 0 0 0 0 0 0 PROST200546600 0 0 40.095 0 0 0 0 0 0 0 0 0 PROST20078710 0 0 33.455 0 0 0 0 0 0 0 00 0 PROST20094000 0 0 27.644 0 0 0 0 0 0 0 0 0 0 PROST20097310 0 0 0 0 00 0 39.281 0 0 0 0 0 PROST20097840 0 16.947 0 0 0 0 0 0 23.921 16.005 00 0 PROST20103820 0 0 0 0 0 39.227 0 0 0 0 0 0 0 PROST20114100 0 0 0 0 039.227 0 0 0 0 0 0 0 PROST20130320 0 12.898 0 12.198 0 0 0 0 0 12.181 00 0 PROST20151370 0 0 0 0 0 39.227 0 0 0 0 0 0 0 PUAEN10000650 0 0 04.545 3.46 0 3.762 8.786 3.392 0 3.564 0 0 PUAEN10001640 0 3.714 0 0 0 00 0 0 3.508 0 0 0 PUAEN20003120 15.692 0 0 0 0 0 0 0 0 0 0 0 0SKNMC20006350 0 0 0 0 0 0 0 0.653 0 0 0 0 2.835 SKNSH10001010 0 0 8.6495.695 8.669 5.492 9.427 5.504 0 11.373 8.93 0 0 SKNSH20007160 15.06910.236 0 0 0 0 0 9.356 0 9.667 15.179 0 0 SKNSH20030640 0 0 0 0 26.755 00 16.987 0 0 0 0 0 SKNSH20094350 19.559 0 0 0 0 0 0 0 0 0 0 0 0SMINT20000070 0 18.929 0 0 0 0 0 0 0 0 0 0 0 SMINT20002320 0 0 39.676 00 0 0 0 0 0 0 0 0 SMINT20030740 2.994 0 0 0 0 0 0 0 0 0 0 0 0SMINT20039050 0 0 0 0 0 0 0 5.94 0 0 0 0 25.802 SMINT20045890 0 0 0 0 011.467 0 0 0 0 0 0 0 SMINT20047290 20.756 0 0 0 0 0 0 0 0 0 0 0 0SMINT20048720 0 0 0 16.241 0 0 0 7.849 12.12 0 0 0 0 SMINT20056240 12.116.438 0 0 0 0 0 0 0 0 0 0 0 SMINT20077920 29.636 11.503 0 5.439 0 5.24618.009 0 8.118 5.432 8.529 0 0 SMINT20088690 0 0 0 0 0 0 0 0 50.098 0 00 0 SMINT20089210 5.552 0 0 7.133 0 0 0 0 0 7.123 22.369 10.807 0SMINT20089600 0 0 0 0 0 18.533 0 0 28.682 0 0 0 0 SMINT20094150 0 0 0 00 0 0 0 0 0 0 0 73.849 SPLEN20005160 0 0 38.129 0 0 0 0 0 0 25.071 0 0 0SPLEN20005370 0 0 0 0 0 0 69.313 0 0 0 0 0 0 SPLEN20012450 0 0 0 0 0 0 00 0 0 0 0 34.138

TABLE 34 SPLEN20024930 0 0 0 24.956 0 0 0 0 0 12.461 0 0 0 SPLEN2004078032.496 0 31.704 0 0 0 0 0 0 0 0 0 0 SPLEN20048800 0 0 0 0 0 0 0 0.678 00 0 0 0 SPLEN20055600 0 0 0 0 0 0 0 0 67.066 0 0 0 0 SPLEN20057830 0 0 00 0 0 32.073 18.727 0 0 0 0 0 SPLEN20063250 0 0 0 0 0 0 0 0 0 0 4.267 00 SPLEN20071820 0 0 0 0 0 0 0 0 0 0 37.578 0 0 SPLEN20073880 0 0 0 0 0 00 0 28.031 0 0 0 0 SPLEN20076470 8.519 0 0 0 0 0 0 0 0 0 0 0 0SPLEN20104690 0 0 0 0 0 0 0 56.874 0 0 0 0 0 SPLEN20114190 0 0 0 0 0 0 00 0 57.672 0 0 0 SPLEN20125230 0 0 0 21.397 0 0 0 41.362 0 0 0 0 0SPLEN20135030 0 0 0 0 0 0 0 20.858 0 0 0 0 0 SPLEN20136700 0 0 0 22.0360 0 0 0 0 22.006 0 0 0 SPLEN20175920 0 0 0 57.706 0 0 0 0 0 0 0 0 0SPLEN20181570 3.585 0 0 0 0 0 0 0 0 0 0 0 0 SPLEN20183020 0 0 0 0 0 0 00 0 21.246 0 0 0 SPLEN20187490 0 0 0 0 0 0 0 22.776 0 0 0 0 0SPLEN20193490 0 0 0 0 0 0 0 0 0 57.672 0 0 0 SPLEN20193790 0 0 0 0 0 0 00 0 0 0 0 10.329 SPLEN20197740 0 0 0 0 0 0 0 0 0 0 33.067 0 0SPLEN20200070 0 0 0 0 67.502 0 0 0 0 0 0 0 0 SPLEN20200340 0 0 0 040.827 0 0 0 0 0 0 0 0 TESOP10000350 0 0 0 0 0 0 0 2.374 0 0 0 3.721 0TESTI20005980 0 0 0 28.345 0 0 0 0 0 0 0 0 0 TESTI20030440 0 0 0 0 0 0 00 0 0 27.24 0 0 TESTI20030610 0 0 0 0 0 7.709 0 7.726 0 0 0 0 0TESTI20031410 0 0 0 0 0 19.238 0 0 0 0 0 15.113 0 TESTI20035330 4.698 00 0 0 5.821 0 5.835 0 0 0 0 25.343 TESTI20047370 0 0 0 0 0 0 0 0 3.037 00 0 0 TESTI20050400 56.537 0 0 0 0 0 0 0 0 0 0 0 0 TESTI20050720 0 0 06.04 0 0 0 0 0 0 0 0 0 TESTI20053780 56.537 0 0 0 0 0 0 0 0 0 0 0 0TESTI20057430 0 0 0 5.84 0 0 0 5.644 0 0 0 0 0 TESTI20057590 0 0 0 0 05.433 0 0 8.409 0 0 0 0 TESTI20057840 0 0 0 0 0 0 0 61.764 0 0 0 0 0TESTI20057880 0 0 0 15.638 0 0 0 0 0 0 0 0 0

TABLE 35 TESTI20059080 0 5.993 0 0 25.882 0 0 5.478 8.458 0 0 0 0TESTI20061200 0 9.745 0 0 0 8.888 0 0 0 0 0 0 0 TESTI20062580 0 0 0 0 00 31.15 0 28.084 0 29.506 0 0 TESTI20063410 0 0 0 9.861 0 9.51 0 014.718 9.848 0 0 0 TESTI20064530 0 0 0 0 0 2.635 0 0 0 5.458 0 0 0TESTI20066280 0 0 0 0 0 0 33.259 0 0 0 0 0 0 TESTI20067480 9.289 6.31 011.934 0 0 0 5.768 0 0 0 0 0 TESTI20071630 0 0 0 62.564 0 0 0 0 0 0 0 00 TESTI20079980 6.472 8.793 6.314 0 0 4.009 6.883 12.056 0 4.152 0 0 0TESTI20081890 0 0 0 0 0 61.711 0 0 0 0 0 0 0 TESTI20089290 0 63.862 0 00 0 0 0 0 0 0 0 0 TESTI20090180 0 0 0 21.786 0 0 0 0 0 0 0 0 0TESTI20105130 2.549 0 2.487 0 4.986 0 0 1.583 0 1.635 0 0 0TESTI20106170 0 18.661 13.402 0 0 8.51 14.608 0 0 26.436 0 0 0TESTI20121040 0 0 0 18.021 0 0 0 0 0 0 0 0 0 TESTI20150920 0 0 0 017.606 0 0 0 17.261 0 18.135 0 0 TESTI20169500 17.008 0 0 0 0 0 0 0 0 00 0 0 TESTI20193080 0 0 0 0 0 0 0 0 0 62.532 0 0 0 TESTI20215310 0 0 0 00 0 0 0 0 0 0 71.689 0 TESTI20221790 0 0 0 0 0 0 0 37.573 0 0 0 0 0TESTI20245860 0 0 0 62.564 0 0 0 0 0 0 0 0 0 TESTI20252690 0 33.792 0 00 0 0 0 0 0 0 0 0 TESTI20254090 0 0 0 0 0 12.041 0 24.136 18.635 0 0 0 0TESTI20261160 0 0 0 0 0 0 0 35 0 0 0 0 0 TESTI20262150 0 0 42.353 0 0 00 0 0 0 0 0 0 TESTI20274960 0 0 0 0 0 0 0 0 0 38.341 0 0 0 THYMU200077500 0 0 29.606 0 0 0 0 0 0 0 0 0 THYMU20009460 0 16.274 0 0 0 0 0 0 0 0 00 0 THYMU20009710 0 0 0 0 0 0 0 0 0 0 0 0 83.62 THYMU20019260 15.885 0 00 0 0 0 0 30.461 0 0 0 0 THYMU20028410 13.579 0 0 0 0 16.825 0 0 0 0 0 00 THYMU20030460 0 0 0 4.612 0 0 0 0 0 4.606 0 0 0 THYMU20031330 0 0 0 00 0 0 0 0 0 0 0 39.843 THYMU20043440 0 0 0 0 0 29.394 0 0 0 0 0 0 0THYMU20044100 0 0 0 28.394 0 0 0 27.444 0 0 0 0 0 THYMU20044520 0 28.8390 0 0 26.302 0 0 0 0 0 0 0 THYMU20049060 0 0 0 0 0 0 0 0 64.474 0 0 0 0

TABLE 36 THYMU20055460 5.716 0 5.577 0 0 0 0 0 0 3.667 0 11.127 0THYMU20055740 0 0 0 54.873 0 0 0 0 0 0 0 0 0 THYMU20071120 3.627 0 3.5390 0 0 0 0 0 0 0 0 0 THYMU20078020 0 56.251 0 0 0 0 0 0 0 0 0 0 0THYMU20089900 0 0 0 0 0 0 0 0 0 0 30.29 0 0 THYMU20091040 0 0 0 0 025.102 0 0 19.425 0 20.408 0 0 THYMU20104480 0 0 22.379 0 0 14.21 0 0 00 0 0 0 THYMU20120240 7.548 0 0 0 0 0 0 0 0 0 0 0 0 THYMU20139160 1.4330.649 0.932 1.841 1.868 2.958 2.031 2.965 3.663 2.451 0 0 0THYMU20143230 0 0 0 0 0 53.973 0 0 0 0 0 0 0 THYMU20150190 0 0 0 0 0 0 00 15.366 0 0 0 43.225 THYMU20157620 0 0 0 0 0 0 0 10.687 0 0 0 16.752 0THYMU20176010 48.624 0 0 0 0 0 0 0 0 0 0 0 0 TKIDN10001920 15.885 0 0 00 0 0 0 30.461 0 0 0 0 TRACH20012490 0 0 0 0 0 8.484 0 0 0 0 0 0 0TRACH20021000 0 14.835 0 0 0 0 0 0 0 0 0 0 58.903 TRACH20026640 0 0 07.419 0 0 0 0 0 0 0 0 0 TRACH20058000 0 0 0 0 0 23.543 0 0 0 0 0 0 0TRACH20090060 0 0 0 0 0 6.122 0 0 0 0 0 0 0 TRACH20159390 0 0 0 0 0 0 034.053 0 0 0 0 0 UMVEN10001380 0 0 3.528 0 0 0 0 0 0 0 0 0 0UTERU10001060 15.424 0 0 0 0 0 32.805 0 0 0 0 0 0 UTERU20000230 0 0 021.808 0 0 0 0 0 21.777 0 0 0 UTERU20000950 1.882 2.557 0 2.418 0 2.3324.002 0 0 4.829 0 0 0 UTERU20026620 5.456 7.413 10.647 0 0 0 0 0 0 0 0 00 UTERU20041970 0 0 3.112 0 0 3.953 0 0 0 0 0 3.105 0 UTERU20065470 0 00 0 0 0 0 0 0 0 49.42 0 0 UTERU20079240 0 0 0 0 19.675 0 0 0 0 0 20.26619.583 0 UTERU20083020 0 0 0 0 0 43.664 8.006 4.675 7.218 4.83 7.5847.328 0 UTERU20089300 0 0 0 0 0 0 0 0 0 0 0 0 72.345 UTERU20089390 8.5190 0 0 0 0 0 0 0 0 0 0 0 UTERU20095100 19.272 0 0 0 0 0 40.989 0 0 0 0 00 UTERU20102260 0 0 0 15.526 0 0 0 0 0 0 0 0 0 UTERU20103200 0 0 0 0 0 00 0 48.185 0 0 0 0 UTERU20127150 0 0 0 0 0 0 0 37.588 0 0 0 0 0UTERU20128560 0 0 0 11.256 0 0 0 0 0 0 0 0 0

TABLE 37 Clone ID FEHRT HEART BRAMY20043630 0 7.465 BRAMY20072870 076.411 BRAMY20227860 0 2.943 BRAWH20093070 0 25.522 BRCAN10001680 014.799 FCBBF30053300 86.185 0 FEBRA20078800 0 33.301 FEBRA20090220 09.681 HCHON20000870 0 23.022 HEART10001420 0 100 HEART10001490 0 14.37HEART20009590 0 100 HEART20019310 0 100 HEART20022200 0 100HEART20031680 0 100 HEART20047640 0 100 HEART20063100 0 100HEART20082570 0 100 HLUNG20083960 0 40.294 PLACE60088240 0 67.95PLACE60120280 0 50.712 PROST20016760 0 8.491 PROST20035170 0 23.745PROST20062820 0 67.646 PROST20127450 0 48.135 SKMUS20006790 0 5.186SKMUS20008730 0 27.003 TESTI20270130 0 83.925

TABLE 38 Clone ID FEKID KIDNE ASTRO20009140 0 19.518 BGGI120010750 04.532 BRACE20054480 0 29.719 BRACE20062580 0 2.613 BRACE20219360 059.494 BRAMY20001510 68.103 0 BRAMY20003540 0 4.676 BRAMY20003880 016.882 BRAMY20043630 0 3.51 BRAMY20204270 0 3.618 CTONG20033750 0 59.93CTONG20039370 0 59.93 CTONG20045500 0 59.93 FCBBF20023490 0 14.59FEBRA20039260 0 7.084 FEBRA20040290 0 7.711 HEART10001490 0 20.269HLUNG20041590 0 4.744 HLUNG20068120 0 11.84 HLUNG20072450 88.657 3.599HLUNG20083960 0 18.946 KIDNE20011600 0 100 KIDNE20016360 0 59.589KIDNE20024380 0 100 KIDNE20027980 0 100 KIDNE20080690 0 5.861KIDNE20081170 0 100 KIDNE20083150 0 100 KIDNE20083620 0 100KIDNE20084030 0 40.03 KIDNE20084040 0 34.084 KIDNE20084730 0 100KIDNE20084800 0 100 KIDNE20086490 0 87.61 KIDNE20086660 0 47.013KIDNE20086970 0 100 KIDNE20087880 0 28.683 KIDNE20088240 0 100KIDNE20089870 0 3.987 KIDNE20091090 0 100 KIDNE20094260 0 100KIDNE20094670 0 59.494 KIDNE20095530 0 100 KIDNE20133460 0 100KIDNE20133880 0 100 KIDNE20134130 0 65.363 KIDNE20134890 0 100KIDNE20137310 0 100 KIDNE20138450 0 38.971 KIDNE20140870 0 22.93KIDNE20141120 0 100 KIDNE20141700 0 100 KIDNE20142680 0 100KIDNE20142900 0 31.732 KIDNE20143200 0 100 KIDNE20147170 0 100KIDNE20148080 0 100 KIDNE20149780 0 60.365 KIDNE20150730 0 100KIDNE20152440 0 100 KIDNE20154330 0 100 KIDNE20154830 0 100KIDNE20155980 0 100 KIDNE20157100 0 100 KIDNE20160360 0 100KIDNE20160960 0 100 KIDNE20163710 0 100 KIDNE20165390 0 100KIDNE20169180 0 100 KIDNE20170400 0 19.556 KIDNE20173150 0 100KIDNE20173430 0 36.673 KIDNE20176030 0 100 KIDNE20181670 0 100KIDNE20182540 0 100 KIDNE20186170 0 100 KIDNE20188630 0 100KIDNE20189890 0 100 KIDNE20189960 0 100 KIDNE20191870 0 100OCBBF20174890 0 32.241 PLACE60073090 0 10.501 PLACE60181870 0 49.921PROST20016760 0 3.992 PUAEN10000650 0 6.676 SKNMC20006350 24.429 0SPLEN20017610 0 42.429 SPLEN20063250 0 3.996 SPLEN20126110 0 50.05SPLEN20135030 0 31.695 TESTI20061200 0 13.537 TESTI20262150 0 40.96THYMU10004280 0 3.534 THYMU20139160 0 2.704 TRACH20011010 0 10.647

TABLE 39 Clone ID FELNG HLUNG BRAMY20001510 0 5.948 BRAMY20043630 015.102 BRAMY20204270 0 7.785 BRAMY20227860 0 1.488 CTONG20029030 028.504 CTONG20168460 0 76.291 CTONG20186290 0 61.67 FEBRA20039260 0 7.62FEBRA20078800 0 33.686 FEBRA20163980 0 38.327 HCHON20000870 0 23.288HLUNG20008460 0 67.54 HLUNG20009260 0 100 HLUNG20009550 0 100HLUNG20010130 0 100 HLUNG20011260 0 100 HLUNG20011440 0 100HLUNG20011460 0 76.577 HLUNG20012140 0 100 HLUNG20014590 0 36.045HLUNG20015070 0 17.804 HLUNG20015180 0 4.723 HLUNG20020500 0 100HLUNG20020850 0 67.488 HLUNG20021450 0 68.006 HLUNG20023030 0 100HLUNG20024050 0 100 HLUNG20025620 0 100 HLUNG20028110 0 76.618HLUNG20029420 0 100 HLUNG20029490 0 81.173 HLUNG20030420 0 100HLUNG20030490 0 100 HLUNG20030610 0 100 HLUNG20031620 0 80.237HLUNG20032460 0 44.037 HLUNG20033060 0 36.529 HLUNG20033310 0 100HLUNG20033350 0 100 HLUNG20034970 0 79.349 HLUNG20037140 0 100HLUNG20037160 0 100 HLUNG20037780 0 44.761 HLUNG20038330 0 100HLUNG20041540 0 100 HLUNG20041590 0 10.207 HLUNG20042730 0 100HLUNG20045340 0 7.67 HLUNG20047070 0 100 HLUNG20050760 0 100HLUNG20051330 0 100 HLUNG20052300 0 23.611 HLUNG20054790 0 100HLUNG20055240 0 100 HLUNG20056560 0 75.961 HLUNG20057380 0 100HLUNG20059240 0 100 HLUNG20060670 0 100 HLUNG20063700 0 100HLUNG20065700 0 62.8 HLUNG20065990 0 100 HLUNG20067810 0 100HLUNG20068120 0 50.947 HLUNG20069350 0 100 HLUNG20070410 0 100HLUNG20072100 0 54.241 HLUNG20072190 0 79.349 HLUNG20072450 0 7.744HLUNG20074330 0 100 HLUNG20079310 0 100 HLUNG20081390 0 66.429HLUNG20081530 0 100 HLUNG20082350 0 100 HLUNG20083330 0 100HLUNG20083480 0 13.123 HLUNG20083840 0 100 HLUNG20083960 0 40.76HLUNG20084790 0 100 HLUNG20085210 0 50.993 HLUNG20088750 0 100HLUNG20092530 0 100 HLUNG20093030 0 100 HLUNG20094130 0 75.987KIDNE20142900 0 68.268 PROST20016760 0 8.589 PROST20052850 0 57.701SKNMC20006350 0 2.134 SMINT20035050 0 6.135 SPLEN20012450 0 25.695TESTI20057590 0 17.804 TESTI20061200 0 29.123 TESTI20067480 0 18.856TESTI20116050 0 30.168 THYMU10004280 0 7.603 THYMU20010180 0 79.349THYMU20139160 0 1.939 TRACH20011010 0 22.907 UTERU20016580 0 43.64UTERU20127030 0 66.318

TABLE 40 Alteration of the expression level of each clone due to TNF-αstimulation to human monocyte cell line THP-1 and alteration of theexpression level of each clone due to co- culture of gastric cancer cellline MKN45 with Helicobacter pylori. ctl, TNF_1h, and TNF_3h in thecolumn of THP-1, respectively, indicate the relative mRNA expressionlevels in unstimulated THP-1, in the cell stimulated with 10 ng/mL TNF-αfor 1 hour, and in the cell stimulated with 10 ng/mL TNF-α for 3 hours;ctl, Hp, and ΔcagE in the column of MKN45 indicate the relative mRNAexpression levels in MKN45 cultured without Helicobacter pylori, in thecells co-cultured with cag PAI- positive Helicobacter pylori (TN2) (at aratio of MKN45:TN2 = 1:100 cells (colonies)) for 3 hours, and in thecells co- cultured with the cagE mutant (TN2ΔcagE) (at a ratio ofMKN45:TN2ΔcagE = 1:100 cells (colonies)) for 3 hours, respectively.[ATAC-PCR] THP-1 MKN45 Clone name ctl TNF_1h TNF_3h ctl Hp ΔcagEASTRO20045840 1.5 2.3 1.9 2.3 2.4 0.2 ASTRO20055930 0.8 1.9 1.4 0.8 0.80.5 ASTRO20088950 1.0 0.2 2.5 1.1 0.3 0.3 BNGH420052350 2.2 2.2 0.0 0.50.5 3.2 BRACE20052530 2.6 1.0 0.3 2.2 1.0 0.9 BRACE20054080 0.8 1.1 1.0BRAMY20003880 1.5 0.9 0.6 1.2 0.0 1.3 BRAMY20027390 0.6 4.2 0.1 2.9 0.40.1 BRAMY20028530 0.5 3.4 4.1 BRAMY20035380 1.3 0.9 0.8 0.5 1.7 0.5BRAMY20036530 1.1 0.3 0.3 BRAMY20050940 0.4 0.0 0.0 0.2 0.2 1.0BRAMY20072440 0.5 0.5 0.1 BRAMY20096930 3.8 5.2 4.7 1.7 2.4 1.7BRAMY20118410 0.8 3.7 0.8 2.7 0.0 0.0 BRAMY20237190 0.0 2.3 0.1BRAWH20055330 2.5 4.7 2.8 1.2 1.3 0.0 BRAWH20078620 1.9 1.2 1.0BRAWH20190530 0.6 0.1 0.0 0.3 0.0 0.0 BRCAN20001480 1.0 3.4 4.1 1.4 1.60.6 BRHIP10000720 0.3 1.8 1.4 0.9 0.0 1.7 BRHIP10001040 0.9 0.7 0.1 0.00.1 0.0 BRHIP20000210 0.6 0.6 0.0 2.0 0.3 0.0 BRSSN20001970 0.8 1.4 1.30.8 0.7 0.5 BRSSN20091190 0.6 0.1 0.8 CD34C20001750 0.0 0.4 2.0CTONG20078340 0.3 2.6 1.6 0.9 0.7 2.4 CTONG20079590 1.0 1.2 0.2 0.1 0.00.0 CTONG20083980 0.0 0.0 0.0 1.3 1.8 1.9 CTONG20085210 0.8 1.2 2.3 0.10.2 0.1 DFNES20063460 1.7 3.6 2.7 1.3 2.0 0.1 DFNES20072990 1.4 1.9 2.05.0 4.9 4.2 FCBBF20029280 1.8 5.5 3.8 2.3 2.2 2.3 FCBBF20032930 0.1 0.10.0 1.7 0.5 0.5 FCBBF20036360 0.6 0.7 0.4 0.4 0.2 0.2 FCBBF30022680 2.91.0 0.3 2.9 1.0 0.3 FCBBF30078600 1.1 2.6 0.6 FCBBF30105080 1.8 1.6 1.90.2 0.1 0.0 FCBBF30169870 1.1 1.2 0.2 1.6 0.3 0.3 FCBBF30225930 2.2 0.81.0 1.1 0.7 0.2 FCBBF50000610 2.1 2.8 2.2 2.0 2.2 1.3 FEBRA20007820 0.01.7 2.4 2.1 1.4 1.2 FEBRA20031280 0.1 1.8 4.5 0.5 0.0 0.0 FEBRA200318101.4 3.9 3.5 1.5 2.1 1.9 FEBRA20039260 2.0 3.0 2.5 FEBRA20046280 1.3 0.30.3 FEBRA20084750 2.5 2.2 0.3 FEBRA20182030 3.0 4.0 4.2 1.6 0.3 0.7HLUNG20041540 0.0 2.2 2.2 1.9 2.4 0.2 HLUNG20092530 0.3 0.3 3.1 0.2 0.20.9 KIDNE20084030 1.6 0.1 0.3 0.1 0.0 0.0 KIDNE20084800 0.6 0.3 0.0 0.50.5 1.1 KIDNE20134130 0.4 0.4 0.5 2.3 1.2 1.6 KIDNE20182540 1.1 0.3 0.3KIDNE20186170 0.0 0.0 0.0 0.6 0.0 0.0 KIDNE20188630 1.5 0.5 0.5 0.4 0.30.0 LIVER20007750 1.3 1.8 0.3 1.9 0.7 0.0 MESAN20021220 1.7 2.6 1.6 2.30.9 0.3 MESAN20084150 0.8 2.6 2.2 1.7 2.1 1.1 NT2NE20059210 1.4 0.4 0.1NT2NE20082130 1.8 1.3 0.5 1.9 0.3 0.3 NT2NE20092950 1.3 2.7 3.4 1.7 2.41.8 NT2RP70031070 0.3 0.9 1.4 0.4 0.4 0.0 OCBBF20012520 0.3 0.3 1.3 0.90.2 1.2 OCBBF20110210 4.5 1.8 0.5 0.5 0.5 4.5 OCBBF20110730 0.4 0.5 0.30.1 0.0 0.0 OCBBF20155030 1.1 1.1 0.9 2.5 0.8 0.3 OCBBF20165900 1.7 4.44.4 1.9 3.3 1.1 OCBBF20170350 0.9 5.4 0.3 0.3 1.7 1.5 OCBBF20176650 0.51.3 0.5 0.7 0.7 0.0 PLACE60006300 0.8 3.2 1.0 0.5 0.5 0.9 PLACE600613702.7 0.8 1.5 1.2 1.0 1.3 PROST20011160 0.2 1.7 2.0 1.3 5.5 1.7PROST20041460 2.9 0.1 1.5 0.6 0.0 0.0 PROST20065100 1.4 1.9 1.6 5.3 0.00.0 PROST20075280 1.7 0.5 0.5 2.6 0.5 0.5 PROST20106060 0.2 0.2 2.0 1.00.6 0.7 PROST20110120 1.2 0.6 0.5 SKMUS20091900 1.2 1.6 0.3 1.2 2.6 0.3SMINT20024140 0.0 0.1 0.0 SMINT20092160 0.5 0.7 0.3 1.3 1.2 0.3SPLEN20040780 1.0 2.8 1.9 0.3 0.8 0.1 SPLEN20110860 2.4 0.1 7.6 1.4 0.10.1 SPLEN20177400 0.8 3.3 1.3 1.3 0.7 0.3 TESTI20038240 0.1 0.0 0.0TESTI20043130 0.0 0.1 0.7 TESTI20046540 1.1 0.8 0.2 1.1 0.8 0.3TESTI20047370 0.4 0.4 0.5 0.6 0.0 0.5 TESTI20057200 2.5 0.0 1.2 1.1 0.40.3 TESTI20057590 0.1 0.1 0.0 3.8 3.5 2.2 TESTI20113940 5.2 0.2 0.2 4.40.4 0.4 TESTI20149880 2.2 0.2 2.2 TESTI20151800 2.1 3.3 2.3 2.5 1.0 0.3TESTI20173050 0.8 0.6 0.5 1.8 1.1 1.0 TESTI20198600 2.2 0.2 2.2TESTI20257910 1.2 0.3 0.3 1.2 0.2 0.7 TESTI20262940 1.5 1.1 0.2 1.1 1.30.2 THYMU20046770 1.7 0.5 0.5 THYMU20058550 1.9 0.1 0.1 THYMU200625200.0 0.0 0.7 0.2 0.3 0.1 THYMU20062770 1.6 1.0 0.3 THYMU20078240 0.3 1.72.9 0.0 1.0 0.1 THYMU20150190 0.2 0.2 0.6 1.4 0.5 1.9 TRACH20125620 1.12.5 1.5 1.4 1.4 1.0 TRACH20149740 9.4 9.4 0.9 1.6 2.1 0.6 TRACH201904602.0 3.3 3.1 0.2 1.1 0.2 UTERU20045200 1.4 2.6 3.9 0.9 2.1 2.5UTERU20064120 0.6 2.7 2.0 0.6 1.7 0.4 UTERU20103200 0.1 0.0 0.9 2.4 1.70.9 ADRGL20046760 0.5 0.5 0.5 ASTRO20055530 0.7 2.4 1.7 0.8 2.1 1.6BRAMY20076130 0.1 1.4 0.2 0.1 0.0 0.0 CTONG20170940 1.6 0.8 0.3 0.5 9.90.5 FCBBF20033360 0.1 0.4 1.4 6.4 0.3 0.7 FCBBF30257370 2.7 0.3 0.3 2.20.1 2.2 FCBBF50001650 1.0 1.6 1.2 1.3 1.0 0.9 FEBRA20040290 0.4 1.9 1.10.4 1.5 1.4 FEBRA20063720 2.9 3.3 3.1 1.5 0.7 1.4 FEBRA20098040 2.5 2.11.5 4.2 0.0 0.3 FEBRA20108580 1.4 2.8 2.8 0.7 0.2 0.2 MESAN20021860 0.11.2 0.2 0.9 1.0 0.9 MESAN20067430 0.8 3.0 1.5 0.0 0.3 0.0 NT2NE200451900.7 0.2 0.2 0.8 0.6 0.2 PROST20016760 1.1 3.4 2.3 SKNSH20007160 0.6 0.30.2 1.1 0.7 0.6 SMINT20006020 2.5 1.0 0.3 2.4 0.3 0.3 TESTI20059370 0.00.2 0.3 0.0 0.0 0.0 TESTI20103690 0.0 0.0 0.0 0.8 0.3 0.3 TESTI202544800.0 0.1 0.6 0.8 0.6 0.0 THYMU10004280 0.2 2.2 0.2 0.2 1.1 1.4THYMU20030460 0.2 0.6 0.2 0.6 0.8 2.4 TRACH20090060 0.5 0.3 2.0 0.0 6.81.7 UTERU20041970 1.6 1.1 1.5 0.0 3.5 2.4 BRAMY20125360 0.8 1.6 1.1 0.00.0 0.0 OCBBF20142290 0.2 0.9 0.3 0.1 0.4 0.0 SKMUS20006790 0.7 0.5 0.31.0 0.8 0.7 TESTI20030610 0.1 2.0 1.7 0.0 0.3 0.0 UTERU20026620 0.4 4.24.2 2.4 2.7 0.9Homology Search Result Data

Data obtained by the homology search for full-length nucleotidesequences and deduced amino acid sequences.

In the result of the search shown below, both units, aa and bp, are usedas length units for the sequences to be compared.

Each data includes Clone name, Definition in hit data, P value, Lengthof sequence to be compared, Homology, and Accession number (No.) of hitdata. These items are shown in this order and separated by adouble-slash mark, //.

-   ADRGL20020290//Human placental equilibrative nucleoside transporter    1 (hENT1) mRNA, complete cds.//1.70E-240//456aa//100%//U81375-   ADRGL20021910//Homo sapiens transmembrane protein B7-H2 ICOS ligand    mRNA, complete cds.//2.50E-88//168aa//100%//AAG01176-   ADRGL20022600//DIAPHANOUS PROTEIN HOMOLOG 1    (P140MDIA).//2.00E-07//121aa//36%//008808-   ADRGL20023920//ABC1 PROTEIN HOMOLOG    PRECURSOR.//1.40E-98//467aa//45%//Q92338-   ADRGL20026790//Homo sapiens PLIC-1 mRNA, complete    cds.//6.10E-05//169aa//31%//AF293384-   ADRGL20027530-   ADRGL20036380-   ADRGL20036840//HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN H    PRECURSOR (HLA-AR) (HLA-12.4).//7.30E-68//131aa//96%//P01893-   ADRGL20040310-   ADRGL20040770-   ADRGL20046760-   ADRGL20047080-   ADRGL20047770-   ADRGL20057560-   ADRGL20059610//GLUCOSYLCERAMIDASE PRECURSOR (EC 3.2.1.45)    (BETA-GLUCOCEREBROSIDASE) (ACID BETA-GLUCOSIDASE)    (D-GLUCOSYL-N-ACYLSPHINGOSINE GLUCOHYDROLASE) (ALGLUCERASE)    (IMIGLUCERASE).//3.00E-94//188aa//93%//P04062-   ADRGL20062330//Homo sapiens trabeculin-alpha mRNA, complete    cds.//1.10E-128//439aa//58%//AF141968-   ADRGL20063770-   ADRGL20066770//elastin microfibril interface located protein [Homo    sapiens].//3.00E-31//210aa//44%//NP_(—)008977-   ADRGL20067320-   ADRGL20079060//Mus musculus mRNA for Ky protein (muscle-specific    protein).//3.80E-266//281aa//84%//AJ293727-   ADRGL20095330-   ASTRO20001910//Rattus norvegicus mRNA for annexin V-binding protein    (ABP-10), partial cds.//2.20E-57//153aa//73%//D64062-   ASTRO20003720-   ASTRO20004820-   ASTRO20006530//Homo sapiens hook1 protein (HOOK1) mRNA, complete    cds.//1.80E-94//383aa//55%//AF044923-   ASTRO20009140//PUTATIVE COMPETENCE-DAMAGE    PROTEIN.//2.70E-06//167aa//29%//P46323-   ASTRO20010010-   ASTRO20010290-   ASTRO20012270-   ASTRO20020240-   ASTRO20020350-   ASTRO20022020-   ASTRO20026320//NAM7 PROTEIN (NONSENSE-MEDIATED mRNA DECAY PROTEIN 1)    (UP-FRAMESHIFT SUPPRESSOR 1).//1.80E-47//432aa//33%//P30771-   ASTRO20027330-   ASTRO20038400//Homo sapiens zinc finger homeobox protein ZHX1 mRNA,    complete cds.//3.40E-78//282aa//42%//AF106862-   ASTRO20045840-   ASTRO20046280//PSU1 PROTEIN.//1.30E-42//228aa//36%//P53550-   ASTRO20047510-   ASTRO20050810//L-RIBULOKINASE (EC    2.7.1.16).//1.10E-43//512aa//30%//P94524-   ASTRO20052420//PROBABLE GUANINE NUCLEOTIDE REGULATORY PROTEIN TIM    (ONCOGENE TIM) (P60 TIM) (TRANSFORMING IMMORTALIZED MAMMARY    ONCOGENE).//4.80E-151//408aa//76%//Q12774-   ASTRO20053430//BAND 4.1-LIKE PROTEIN 4 (NBL4    PROTEIN).//1.80E-58//307aa//38%//057457-   ASTRO20055530-   ASTRO20055570//MAJOR PRION PROTEIN PRECURSOR (PRP) (PRP27-30)    (PRP33-35C) (ASCR).//5.40E-72//137aa//100%//P04156-   ASTRO20055930-   ASTRO20058960//DNA damage inducible protein homolog—fission yeast    (Schizosaccharomyces pombe)//1.90E-14//205aa//31%//T39541-   ASTRO20069200-   ASTRO20075150//TNF RECEPTOR ASSOCIATED FACTOR 3 (CD40 RECEPTOR    ASSOCIATED FACTOR 1) (CRAF1) (CD40 BINDING PROTEIN) (CD40BP) (LMP1    ASSOCIATED PROTEIN) (LAP1).//1.00E-25//60aa//98%//Q13114-   ASTRO20076660-   ASTRO20085080//TIPD PROTEIN.//1.80E-58//307aa//37%//015736-   ASTRO20088950//LACTASE-PHLORIZIN HYDROLASE PRECURSOR    (LACTASE-GLYCOSYLCERAMIDASE) [INCLUDES: LACTASE (EC 3.2.1.108);    PHLORIZIN HYDROLASE (EC 3.2.1.62)].//7.80E-85//331aa//48%//P09848-   ASTRO20089600//Mus musculus sacsin gene, complete    cds.//1.10E-05//198aa//26%//AF193557-   ASTRO20090680//M. musculus mRNA for    IB3/5-polypeptide.//1.60E-173//412aa//78%//X79131-   ASTRO20091180-   ASTRO20091770-   ASTRO20141740-   BGGI120000670//Rattus norvegicus myosin heavy chain Myr 8b mRNA,    complete cds.//1.60E-05//86aa//36%//AY004215-   BGGI120010750//Rattus norvegicus mRNA for SECIS binding protein 2    (sbp2 gene).//7.90E-305//812aa//71%//AJ251245-   BNGH410000570-   BNGH420008150//Human SH3 domain-containing proline-rich kinase    (sprk) mRNA, complete cds.//3.40E-139//326aa//82%//U07747-   BNGH420014060-   BNGH420015760//Mus musculus mRNA for JNK-binding protein JNKBP1,    complete cds.//1.60E-130//381aa//60%//AB029482-   BNGH420021680-   BNGH420023870//RIBONUCLEASE INHIBITOR.//4.70E-41//314aa//34%//P10775-   BNGH420024870-   BNGH420035290//MYOSIN HEAVY CHAIN KINASE B (EC 2.7.1.129) (MHCK    B).//7.60E-37//273aa//35%//P90648-   BNGH420036410-   BNGH420040760-   BNGH420042910-   BNGH420045380-   BNGH420046790//immunoglobulin lambda light chain variable region    [Homo sapiens].//5.00E-47//84aa//100%//AAG24674-   BNGH420052350-   BNGH420059680//DIPZ PROTEIN.//3.00E-13//166aa//31%//Q10801-   BNGH420061350-   BNGH420062340-   BNGH420070370//ZINC FINGER PROTEIN GLI1    (GLI).//3.20E-65//165aa//59%//P47806-   BNGH420074600//DNA-DIRECTED RNA POLYMERASE III 128 KDA POLYPEPTIDE    (EC 2.7.7.6) (RNA POLYMERASE III SUBUNIT    2).//5.40E-214//522aa//72%//P25167-   BNGH420075940-   BNGH420077980//Rattus norvegicus ankyrin binding cell adhesion    molecule neurofascin mRNA, alternatively spliced form, partial    cds.//0//588aa//98%//U81036-   BNGH420085100-   BNGH420086030//N-CHIMAERIN (NC) (N-CHIMERIN) (ALPHA CHIMERIN)    (A-CHIMAERIN).//2.30E-21//130aa//40%//P15882-   BNGH420087430//Mus musculus mRNA 1 for phtf    protein.//5.80E-118//237aa//57%//AJ133721-   BRACE10000510//KERATIN, ULTRA HIGH-SULFUR MATRIX PROTEIN (UHS    KERATIN).//4.70E-12//132aa//37%//P26371-   BRACE20003310//ZINC FINGER PROTEIN 85 (ZINC FINGER PROTEIN HPF4)    (HTF1).//1.00E-205//504aa//71%//Q03923-   BRACE20007330//RING CANAL PROTEIN (KELCH    PROTEIN).//4.60E-66//562aa//31%//Q04652-   BRACE20009050-   BRACE20014450//Mus musculus mRNA for Ndr1 related protein Ndr2,    complete cds.//3.20E-150//291aa//95%//AB033921-   BRACE20017790-   BRACE20018810-   BRACE20025820-   BRACE20038920-   BRACE20050870//PRE-mRNA SPLICING HELICASE BRR2 (EC    3.6.1.-).//8.40E-59//584aa//31%//P32639-   BRACE20051600-   BRACE20051930//NEUROPILIN PRECURSOR (A5 PROTEIN) (A5    ANTIGEN).//5.50E-20//179aa//30%//P28824-   BRACE20052430//Homo sapiens AMSH mRNA, complete    cds.//4.30E-75//272aa//53%//U73522-   BRACE20052530-   BRACE20054080-   BRACE20054480-   BRACE20054600//Xenopus laevis mRNA for Kielin, complete    cds.//4.30E-70//205aa//60%//AB026192-   BRACE20055560-   BRACE20057870-   BRACE20059110-   BRACE20059810-   BRACE20061620//ZINC-BINDING PROTEIN    A33.//3.60E-30//329aa//28%//Q02084-   BRACE20062580-   BRACE20063540//MEROZOITE SURFACE PROTEIN CMZ-8    (FRAGMENT).//1.60E-10//164aa//35%//P09125-   BRACE20065470//Xenopus laevis ubiquitin-like fusion protein mRNA,    complete cds.//6.70E-63//170aa//71%//L08474-   BRACE20066360-   BRACE20068710-   BRACE20069000//CLN3 PROTEIN (BATTENIN) (BATTEN'S DISEASE    PROTEIN).//1.20E-147//279aa//100%//Q13286-   BRACE20069110-   BRACE20069440-   BRACE20079200//Xenopus laevis mRNA for Kielin, complete    cds.//3.10E-15//63aa//58%//AB026192-   BRACE20079370//microtubule associated-protein orbit [Drosophila    melanogaster].//8.00E-42//282aa//36%//BAA94248-   BRACE20097540//Homo sapiens protein serine/threonine phosphatase 4    regulatory subunit 1 (PP4R1) mRNA, complete    cds.//2.80E-96//193aa//96%//AF111106-   BRACE20098860-   BRACE20099070-   BRACE20194670//UDP-GALACTOSE TRANSLOCATOR (UDP-GALACTOSE    TRANSPORTER) (UGT) (UDP-GAL-TR).//1.40E-32//72aa//98%//P78381-   BRACE20196180//Homo sapiens HMG domain protein HMGX2 (HMGX2) mRNA,    complete cds.//6.90E-154//235aa//91%//AF146223-   BRACE20196960-   BRACE20200770//PROTEIN MOV-10.//3.30E-24//113aa//50%//P23249-   BRACE20200970-   BRACE20204670//PROTEIN-TYROSINE PHOSPHATASE ALPHA PRECURSOR (EC    3.1.3.48) (R-PTP-ALPHA).//4.30E-237//428aa//99%//P18433-   BRACE20205840-   BRACE20207420-   BRACE20212450-   BRACE20215410//PROTEIN-TYROSINE PHOSPHATASE YVH1 (EC 3.1.3.48)    (PTPASE YVH1).//2.90E-08//136aa//31%//Q02256-   BRACE20216700-   BRACE20216950//4F2 CELL-SURFACE ANTIGEN HEAVY CHAIN (4F2HC)    (LYMPHOCYTE ACTIVATION ANTIGEN 4F2 LARGE SUBUNIT) (4F2 HEAVY CHAIN    ANTIGEN) (CD98 ANTIGEN).//4.80E-66//94aa//90%//P08195-   BRACE20219360-   BRAMY10000980-   BRAMY10001730-   BRAMY20000210-   BRAMY20000250-   BRAMY20001510//Homo sapiens RING zinc finger protein (RZF) mRNA,    complete cds.//3.80E-131//245aa//99%//AF037204-   BRAMY20003540//1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE    PHOSPHODIESTERASE DELTA 1 (EC 3.1.4.11) (PLC-DELTA-1) (PHOSPHOLIPASE    C-DELTA-1) (PLC-III).//0//745aa//99%//P51178-   BRAMY20003880-   BRAMY20005080//UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 16 (EC    3.1.2.15) (UBIQUITIN THIOLESTERASE 16) (UBIQUITIN-SPECIFIC    PROCESSING PROTEASE 16) (DEUBIQUITINATING ENZYME 16) (UBIQUITIN    PROCESSING PROTEASE UBP-M).//2.70E-46//93aa//100%//Q9Y5T5-   BRAMY20013670//PECANEX PROTEIN.//1.80E-84//300aa//56%//P18490-   BRAMY20016780-   BRAMY20020440-   BRAMY20021580-   BRAMY20023390-   BRAMY20023640-   BRAMY20024790-   BRAMY20027390-   BRAMY20027990//Homo sapiens NEDL1 mRNA for NEDD4-like ubiquitin    ligase 1, complete cds.//4.60E-158//294aa//100%//AB048365-   BRAMY20028530-   BRAMY20028620//NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE    [CARBOXYLATING] (EC 2.4.2.19) (QUINOLINATE PHOSPHORIBOSYLTRANSFERASE    [DECARBOXYLATING]) (QAPRTASE).//9.70E-18//53aa//84%//Q15274-   BRAMY20035380//ZINC TRANSPORTER 1    (ZNT-1).//5.60E-40//211aa//35%//Q62720-   BRAMY20035830//Homo sapiens RCC1-like G exchanging factor RLG mRNA,    complete cds.//3.60E-103//251aa//75%//AF060219-   BRAMY20036530-   BRAMY20036810-   BRAMY20038980//INTRACELLULAR PROTEIN TRANSPORT PROTEIN    US01.//3.40E-17//407aa//23%//P25386-   BRAMY20039290-   BRAMY20040580//ZINC FINGER PROTEIN    135.//1.70E-29//115aa//54%//P52742-   BRAMY20043520-   BRAMY20043630//Homo sapiens Ras-binding protein SUR-8 mRNA, complete    cds.//1.30E-167//364aa//88%//AF068920 BRAMY20044920//UBIQUITIN    CARBOXYL-TERMINAL HYDROLASE 4 (EC 3.1.2.15) (UBIQUITIN    THIOLESTERASE 4) (UBIQUITIN-SPECIFIC PROCESSING PROTEASE 4)    (DEUBIQUITINATING ENZYME 4) (UBIQUITOUS NUCLEAR PROTEIN    HOMOLOG).//7.60E-28//86aa//47%//Q13107-   BRAMY20045210-   BRAMY20045420-   BRAMY20047560-   BRAMY20050640-   BRAMY20050940-   BRAMY20051820//Human mRNA for Doc2 (Double C2), complete    cds.//1.90E-49//102aa//99%//D31897-   BRAMY20052440-   BRAMY20053910-   BRAMY20055760//POTENTIAL PHOSPHOLIPID-TRANSPORTING ATPASE VA (EC    3.6.1.-).//5.80E-130//393aa//59%//054827-   BRAMY20056620//Homo sapiens mccb mRNA for non-biotin containing    subunit of 3-methylcrotonyl-CoA carboxylase, complete    cds.//3.00E-106//203aa//100%//AB050049-   BRAMY20056840//UBE-1c2//2.40E-74//261aa//53%//AB030505-   BRAMY20063750//Homo sapiens HRIHFB2007 mRNA, partial    cds.//3.40E-139//253aa//99%//AB015330-   BRAMY20072440-   BRAMY20072870//ACETYL-COENZYME A SYNTHETASE (EC 6.2.1.1)    (ACETATE-COA LIGASE) (ACYL-ACTIVATING    ENZYME).//2.50E-15//88aa//46%//P16929-   BRAMY20073080-   BRAMY20074110-   BRAMY20074860-   BRAMY20076100//STEROIDOGENIC FACTOR 1 (STF-1) (SF-1) (STEROID    HORMONE RECEPTOR AD4BP) (FUSHI TARAZU FACTOR HOMOLOG    1).//4.80E-66//132aa//94%//P50569-   BRAMY20076130-   BRAMY20076530-   BRAMY20083330//SYNAPSIN I.//4.50E-05//155aa//29%//P17599-   BRAMY20083820-   BRAMY20089770//P2X PURINOCEPTOR 7 (ATP RECEPTOR) (P2×7) (PURINERGIC    RECEPTOR) (P2Z RECEPTOR).//3.30E-136//242aa//99%//Q99572-   BRAMY20091230//MITOCHONDRIAL UNCOUPLING PROTEIN 4 (UCP    4).//4.60E-121//224aa//100%//095847-   BRAMY20093490//Mus musculus ubiquitin-protein ligase E3-alpha (Ubr1)    mRNA, complete cds.//7.80E-43//139aa//55%//AF061555-   BRAMY20094890//A KINASE ANCHOR PROTEIN 4 PRECURSOR (MAJOR FIBROUS    SHEATH PROTEIN) (FSC1) (P82).//4.60E-06//131aa//27%//Q60662-   BRAMY20095080-   BRAMY20095570-   BRAMY20096930//Torpedo marmorata mRNA for male sterility protein    2-like protein (ms21 gene).//2.00E-63//139aa//82%//AJ272073-   BRAMY20100680-   BRAMY20102900//Homo sapiens RU1 (RU1) mRNA, complete    cds.//1.20E-47//151aa//58%//AF168132-   BRAMY20107980-   BRAMY20111780//ZINC FINGER PROTEIN    135.//1.00E-139//416aa//57%//P52742-   BRAMY20117670//Mus musculus mmDNAJA4 mRNA for mmDj4, complete    cds.//3.20E-118//239aa//90%//AB032401-   BRAMY20118410-   BRAMY20118490//GLYCEROL KINASE 2 (EC 2.7.1.30) (ATP:GLYCEROL    3-PHOSPHOTRANSFERASE 2) (GLYCEROKINASE 2) (GK    2).//1.80E-48//247aa//40%//Q9X1E4-   BRAMY20120170-   BRAMY20123400-   BRAMY20124970-   BRAMY20125170-   BRAMY20125360//L-ASPARAGINASE (EC 3.5.1.1) (L-ASPARAGINE    AMIDOHYDROLASE).//3.30E-53//148aa//43%//Q9ZSD6-   BRAMY20125550//Homo sapiens mRNA for 28 kD interferon responsive    protein (IFRG28 gene).//4.40E-16//155aa//33%//AJ251832-   BRAMY20126910-   BRAMY20127310-   BRAMY20127760-   BRAMY20134050//NUCLEOSOME ASSEMBLY PROTEIN 1-LIKE 2 (BRAIN-SPECIFIC    PROTEIN, X-LINKED).//1.40E-25//109aa//56%//P51860-   BRAMY20135720-   BRAMY20137360//Homo sapiens gene for TU12B1-TY, exon 12 and complete    cds.//2.10E-18//257aa//31%//AB032786-   BRAMY20139440-   BRAMY20139750-   BRAMY20143870//PEPTIDYL-TRNA HYDROLASE (EC 3.1.1.29)    (PTH).//5.80E-27//182aa//35%//P96386-   BRAMY20152510//PROTEIN-TYROSINE PHOSPHATASE STRIATUM-ENRICHED (EC    3.1.3.48) (STEP) (NEURAL-SPECIFIC PROTEIN-TYROSINE PHOSPHATASE)    (FRAGMENT).//4.80E-293//537aa//97%//P54829-   BRAMY20155500-   BRAMY20158550//CALMODULIN.//1.60E-15//116aa//42%//P04352-   BRAMY20159250-   BRAMY20160020-   BRAMY20173480-   BRAMY20190550//EPIDERMAL GROWTH FACTOR RECEPTOR SUBSTRATE SUBSTRATE    15 (PROTEIN EPS15) (AF-1P PROTEIN).//2.20E-226//464aa//89%//P42566-   BRAMY20194680-   BRAMY20204270-   BRAMY20206340//GUANINE NUCLEOTIDE-BINDING PROTEIN BETA SUBUNIT-LIKE    PROTEIN.//4.20E-07//151aa//27%//P38011-   BRAMY20219620-   BRAMY20221600//H. sapiens mRNA for novel T-cell activation    protein.//1.60E-130//245aa//99%//X94232-   BRAMY20223010//Mus musculus leucine-rich glioma-inactivated 1    protein precursor, (Lgi1) mRNA, complete    cds.//2.00E-79//269aa//52%//AF246818-   BRAMY20225250-   BRAMY20225320-   BRAMY20227230-   BRAMY20227860//Homo sapiens dickkopf-3 (DKK-3) mRNA, complete    cds.//2.30E-69//147aa//92%//AF177396-   BRAMY20227960-   BRAMY20231150//PUTATIVE ACID PHOSPHATASE F26C11.1 (EC    3.1.3.2).//2.30E-55//322aa//39%//Q09549-   BRAMY20234820//Homo sapiens mitotic checkpoint protein (MAD1) mRNA,    complete cds.//1.30E-286//561aa//100%//AF123318-   BRAMY20237190-   BRAMY20238630//TETRATRICOPEPTIDE REPEAT PROTEIN    4.//1.20E-147//276aa//99%//095801-   BRAMY20243120-   BRAMY20244490//ADENYLATE KINASE ISOENZYME 1 (EC 2.7.4.3) (ATP-AMP    TRANSPHOSPHORYLASE) (AK1) (MYOKINASE).//2.50E-19//119aa//37%//P00571-   BRAMY20245140//Rattus norvegicus potassium channel (erg2) mRNA,    complete cds.//1.00E-178//427aa//81%//AF016192-   BRAMY20245350-   BRAMY20245760//Araneus diadematus fibroin-4 mRNA, partial    cds.//7.90E-05//285aa//22%//U47856-   BRAMY20251210//EPHRIN TYPE-A RECEPTOR 7 PRECURSOR (EC 2.7.1.112)    (TYROSINE-PROTEIN KINASE RECEPTOR EHK-3) (EPH HOMOLOGY KINASE-3)    (EMBRYONIC BRAIN KINASE) (EBK) (DEVELOPMENTAL KINASE 1)    (MDK-1).//3.80E-94//268aa//66%//Q61772-   BRAMY20251750//Homo sapiens BRI3 mRNA, complete    cds.//2.80E-131//242aa//95%//AF272043-   BRAMY20263000//DYSTROPHIA MYOTONICA-CONTAINING WD REPEAT MOTIF    PROTEIN (DMR-N9 PROTEIN).//2.60E-134//430aa//59%//Q08274-   BRAMY20267780-   BRAMY20269040-   BRAMY20271140-   BRAMY20274510//60S RIBOSOMAL PROTEIN    L12.//1.10E-39//102aa//82%//P30050-   BRAMY20285650-   BRAMY20287400-   BRAWH20014590//ZAKI-4 PROTEIN.//3.10E-92//187aa//93%//Q14206-   BRAWH20020470-   BRAWH20020600-   BRAWH20021910//FATTY ACYL-COA HYDROLASE PRECURSOR, MEDIUM CHAIN (EC    3.1.2.14) (THIOESTERASE B).//1.30E-111//450aa//49%//Q04791-   BRAWH20025490-   BRAWH20026010//AD021 protein [Homo    sapiens]//4.00E-55//245aa//44%//NP_(—)057697-   BRAWH20027250-   BRAWH20030000-   BRAWH20039640//SLIT PROTEIN PRECURSOR.//6.10E-19//282aa//31%//P24014-   BRAWH20040680//PUTATIVE TRANSCRIPTION ELONGATION FACTOR S-II    (TFIIS).//5.90E-06//179aa//29%//P52652-   BRAWH20047790-   BRAWH20050740//ZINC FINGER PROTEIN 151 (POLYOMAVIRUS LATE INITIATOR    PROMOTER BINDING PROTEIN) (LP-1) (ZINC FINGER PROTEIN    Z13).//1.60E-16//235aa//30%//Q60821-   BRAWH20055240-   BRAWH20055330-   BRAWH20055780-   BRAWH20058120-   BRAWH20063010//SPLICEOSOME ASSOCIATED PROTEIN 49 (SAP 49)    (SF3B53).//2.60E-06//121aa//33%//Q15427-   BRAWH20078080-   BRAWH20078620-   BRAWH20080580//ZINC FINGER PROTEIN 84 (ZINC FINGER PROTEIN    HPF2).//1.00E-116//316aa//63%//P51523-   BRAWH20082550-   BRAWH20082920//Human TFIIIC Box B-binding subunit mRNA, complete    cds.//1.90E-36//72aa//100%//U02619-   BRAWH20093040//PROTEIN KINASE CLK2 (EC    2.7.1.-).//2.70E-86//162aa//96%//P49760    BRAWH20093070//SYNAPSIN.//4.80E-06//245aa//28%//Q24546-   BRAWH20094900//Mus musculus mRNA for sialidase, complete    cds.//5.70E-73//310aa//50%//AB026842-   BRAWH20095900//ZINC FINGER PROTEIN 184    (FRAGMENT).//1.20E-170//631aa//48%//Q99676 BRAWH20173790-   BRAWH20174330//SPLICEOSOME ASSOCIATED PROTEIN 49 (SAP 49)    (SF3B53).//4.50E-06//121aa//33%//Q15427-   BRAWH20175230-   BRAWH20175340-   BRAWH20176850//Mus musculus mRNA for nuclear protein ZAP, complete    cds.//9.50E-151//619aa//53%//AB033168-   BRAWH20182670-   BRAWH20183170//GRR1 PROTEIN.//9.30E-13//218aa//28%//P24814-   BRAWH20185260-   BRAWH20185270-   BRAWH20186010-   BRAWH20188750//BIOTIN SYNTHESIS PROTEIN    BIOC.//5.80E-11//190aa//27%//P36571-   BRAWH20190530//Homo sapiens BNPI mRNA for brain-specific    Na-dependent inorganic phosphate cotransporter, complete    cds.//2.10E-109//118aa//100%//AB032436-   BRAWH20190550//PUTATIVE SERINE/THREONINE-PROTEIN KINASE PKWA (EC    2.7.1.-).//1.30E-05//172aa//29%//P49695-   BRAWH20191980//PROLINE OXIDASE, MITOCHONDRIAL PRECURSOR (EC 1.5.3.-)    (PROLINE DEHYDROGENASE).//2.10E-125//234aa//99%//043272-   BRCAN10000760//UREA TRANSPORTER,    ERYTHROCYTE.//1.30E-212//389aa//100%//Q13336-   BRCAN10001050//PEANUT-LIKE PROTEIN 2 (BRAIN PROTEIN    H5).//1.40E-62//122aa//98%//043236-   BRCAN10001680-   BRCAN20001480-   BRCAN20004180//alpha-1C-adrenergic receptor splice form    2—human//1.10E-22//76aa//76%//S65657-   BRCAN20005230//HEPARIN SULFATE N-DEACETYLASE/N-SULFOTRANSFERASE (EC    2.8.2.-) (N-HSST) (N-HEPARIN SULFATE SULFOTRANSFERASE) (GLUCOSAMINYL    N-DEACETYLASE/N-SULFOTRANSFERASE).//8.90E-15//168aa//28%//P52849-   BRCAN20005410//Human 1(3)mbt protein homolog mRNA, complete    cds.//2.00E-95//378aa//50%//U89358-   BRCOC10000400-   BRCOC20000470//Homo sapiens DEME-6 mRNA, partial    cds.//7.30E-37//252aa//28%//AF007170-   BRCOC20003600//VACUOLAR ATP SYNTHASE SUBUNIT AC45 PRECURSOR (EC    3.6.1.34) (V-ATPASE AC45 SUBUNIT).//5.90E-192//418aa//85%//P40682-   BRHIP10000720-   BRHIP10001040//tweety homolog 1 (Drosophila) [Mus    musculus]//1.30E-68//311aa//44%//NP_(—)067299-   BRHIP20000210-   BRHIP20003590-   BRHIP20005060-   BRSSN20001970-   BRSSN20005610//Mus musculus semaphorin cytoplasmic domain-associated    protein 3A (Semcap3) mRNA, complete    cds.//6.30E-225//730aa//60%//AF127084-   BRSSN20005660-   BRSSN20066440//ZINC FINGER PROTEIN    202.//3.60E-37//169aa//37%//095125-   BRSSN20074640//HYPOTHETICAL 35.8 KDA PROTEIN IN PRP16—SRP40    INTERGENIC REGION.//4.50E-20//217aa//28%//P36163-   BRSSN20091190-   BRSSN20092440-   BRSSN20093890//Homo sapiens mRNA for Kelch motif containing protein,    complete cds.//8.40E-13//203aa//30%//AB026190-   CD34C20001750//MHC CLASS INK CELL RECEPTOR PRECURSOR (NATURAL KILLER    ASSOCIATED TRANSCRIPT 4) (NKAT-4).//1.10E-18//214aa//35%//P43630-   CTONG10000090-   CTONG20000340-   CTONG20002790-   CTONG20004110//Mus musculus ankycorbin mRNA, complete    cds.//6.20E-55//1006aa//24%//AF202315-   CTONG20004520//development- and differentiation-enhancing factor 2;    PYK2 C terminus-associated protein [Homo    sapiens].//2.00E-86//310aa//81%//NP_(—)003878-   CTONG20007660//Rattus norvegicus caspase recruitment domain protein    9 mRNA, complete cds.//7.30E-28//319aa//32%//AF311288-   CTONG20008190//YPT1-RELATED PROTEIN 2.//3.00E-30//160aa//40%//P17609-   CTONG20008460-   CTONG20015240-   CTONG20017490//SEMAPHORIN 4A PRECURSOR (SEMAPHORIN B) (SEMA    B).//3.10E-273//607aa//82%//Q62178-   CTONG20020660-   CTONG20020950//ZINC FINGER PROTEIN 37 (ZFP-37) (MALE GERM CELL    SPECIFIC ZINC FINGER PROTEIN).//7.40E-23//258aa//25%//P17141-   CTONG20027660-   CTONG20029030//Homo sapiens Ras-binding protein SUR-8 mRNA, complete    cds.//8.30E-25//402aa//28%//AF068920-   CTONG20030280//VEGETATIBLE INCOMPATIBILITY PROTEIN    HET-E-1.//2.90E-12//303aa//25%//Q00808-   CTONG20031150-   CTONG20031890-   CTONG20032930//microtubule associated-protein orbit [Drosophila    melanogaster]//1.00E-79//913aa//30%//BAA94248-   CTONG20033500-   CTONG20033610//Rattus norvegicus SNIP-a mRNA, complete    cds.//2.50E-145//567aa//41%//AF156981-   CTONG20033750//Drosophila melanogaster AAA family protein Bor (bor)    mRNA, complete cds.//1.40E-174//492aa//66%//AF227209-   CTONG20035240-   CTONG20036800-   CTONG20036990//BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE    PROTEOGLYCAN CORE PROTEIN PRECURSOR (HSPG) (PERLECAN)    (PLC).//1.10E-10//247aa//27%//Q05793-   CTONG20039370-   CTONG20041150//Streptomyces ansochromogenes strain 7100 SanE (sanE)    gene, complete cds.//5.20E-05//133aa//35%//AF228524-   CTONG20041260//Mus musculus retinoic acid-responsive protein (Stra6)    mRNA, complete cds.//1.30E-238//602aa//74%//AF062476-   CTONG20042640//NEUROBLAST DIFFERENTIATION ASSOCIATED PROTEIN AHNAK    (DESMOYOKIN) (FRAGMENTS).//0//797aa//73%//Q09666-   CTONG20044230//Mus musculus zinc finger protein (Mtsh1) mRNA,    partial cds.//1.40E-289//601aa//89%//AF191309-   CTONG20044870-   CTONG20045500//ANION EXCHANGE PROTEIN 3 (CARDIAC/BRAIN BAND 3-LIKE    PROTEIN) (CAE3/BAE3).//2.00E-19//276aa//30%//P48751-   CTONG20046690-   CTONG20049480-   CTONG20050490-   CTONG20051100//PUTATIVE METHYLTRANSFERASE (EC    2.1.1.-).//3.50E-29//72aa//87%//043709-   CTONG20051450//testis development protein PRTD [Homo    sapiens].//9.00E-50//140aa//85%//AAG33852-   CTONG20052780//Homo sapiens mRNA for SH3 binding protein, complete    cds.//8.00E-21//125aa//42%//AB005047-   CTONG20053990//ZINC FINGER PROTEIN 195.//4.30E-08//40aa//75%//014628-   CTONG20055670-   CTONG20055850//Rattus norvegicus golgi peripheral membrane protein    p65 (GRASP65) mRNA, complete cds.//1.10E-99//248aa//78%//AF015264-   CTONG20056150-   CTONG20057750-   CTONG20057950-   CTONG20059130//Mus musculus prominin-like protein mRNA, partial    cds.//7.50E-103//259aa//77%//AF128113-   CTONG20060040-   CTONG20061290-   CTONG20062730-   CTONG20063770//M-PHASE PHOSPHOPROTEIN 9    (FRAGMENT).//1.80E-96//184aa//100%//Q99550-   CTONG20063930//BETA-CHIMAERIN    (BETA-CHIMERIN).//3.50E-31//189aa//34%//Q03070-   CTONG20065240-   CTONG20065680-   CTONG20066110//Homo sapiens DEME-6 mRNA, partial    cds.//8.70E-164//557aa//53%//AF007170-   CTONG20068360//MITOCHONDRIAL CARNITINE/ACYLCARNITINE CARRIER PROTEIN    (CARNITINE/ACYLCARNITINE TRANSLOCASE)    (CAC).//8.00E-30//248aa//35%//P97521-   CTONG20069320-   CTONG20069420-   CTONG20070090-   CTONG20070720//N-CHIMAERIN (NC) (N-CHIMERIN) (ALPHA CHIMERIN)    (A-CHIMAERIN).//9.20E-25//180aa//33%//P30337-   CTONG20070780//SPERM-SPECIFIC ANTIGEN 2 (CLEAVAGE SIGNAL-1 PROTEIN)    (CS-1).//1.90E-122//249aa//97%//P28290-   CTONG20070910//Homo sapiens mRNA for 26S proteasome subunit p55,    complete cds.//7.70E-227//400aa//100%//AB003103-   CTONG20071040//BETA CRYSTALLIN B2    (BP).//6.80E-25//195aa//34%//P26775-   CTONG20071680//HYPOTHETICAL 33.6 KDA PROTEIN IN TDK-PRFA INTERGENIC    REGION.//7.40E-14//328aa//23%//P45869-   CTONG20072930//ZINC FINGER PROTEIN 41    (FRAGMENT).//4.10E-216//542aa//69%//P51814-   CTONG20073990-   CTONG20074000//Mus musculus teashirt 2 (Tsh2) gene, partial    cds.//0//1024aa//89%//AF207880-   CTONG20074170-   CTONG20074740-   CTONG20076230-   CTONG20076810//site-1 protease of sterol regulatory element binding    proteins [Cricetulus griseus]//2.80E-245//463aa//93%//AF078105-   CTONG20077760//SYNAPSIN I.//1.70E-08//209aa//32%//P17599-   CTONG20078340//SUPPRESSOR PROTEIN    SRP40.//4.10E-08//282aa//26%//P32583-   CTONG20079590//ALPHA-N-ACETYLGALACTOSAMINIDE    ALPHA-2,6-SIALYLTRANSFERASE (EC 2.4.99.-) (ST6GALNACIII)    (STY).//1.80E-151//305aa//85%//Q64686-   CTONG20080140//HYPOTHETICAL 60.3 KDA PROTEIN R13G10.2 IN CHROMOSOME    III.//8.40E-29//179aa//40%//Q21988-   CTONG20081840-   CTONG20083430-   CTONG20083980//VASODILATOR-STIMULATED PHOSPHOPROTEIN    (VASP).//4.50E-10//113aa//34%//P50552-   CTONG20084020-   CTONG20084660//ZINC FINGER PROTEIN    165.//3.30E-33//142aa//57%//P49910-   CTONG20085210//MONO- AND DIACYLGLYCEROL LIPASE PRECURSOR (EC    3.1.1.-) (MDGL).//3.60E-06//94aa//34%//P25234-   CTONG20133720-   CTONG20165590-   CTONG20165750//SON PROTEIN (SON3).//4.40E-239//427aa//99%//P18583-   CTONG20166580-   CTONG20167750-   CTONG20168240-   CTONG20168460-   CTONG20169040//KERATIN, TYPE I CYTOSKELETAL 15 (CYTOKERATIN 15)    (K15) (CK 15).//6.00E-112//223aa//99%//P19012-   CTONG20169530-   CTONG20170940//MYOTROPHIN (V-1 PROTEIN) (GRANULE CELL    DIFFERENTIATION PROTEIN).//4.60E-10//93aa//36%//P80144-   CTONG20174290//TRICHOHYALIN.//1.30E-07//340aa//21%//P37709-   CTONG20174440-   CTONG20174580//Homo sapiens mRNA for vascular Rab-GAP/TBC-containing    protein complete cds.//1.00E-115//335aa//61%//NP_(—)008994-   CTONG20176040//ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 3    (ARD3).//1.70E-34//155aa//43%//P37996-   CTONG20179390-   CTONG20179890-   CTONG20179980-   CTONG20180620-   CTONG20180690-   CTONG20181350-   CTONG20183430//ANKYRIN 2 (BRAIN ANKYRIN) (ANKYRIN B) (ANKYRIN,    NONERYTHROID).//4.60E-30//311aa//32%//Q01484-   CTONG20183830//IRLB [Homo sapiens]//1.50E-104//191aa//100%//CAA45013-   CTONG20184130-   CTONG20184830//ATP-BINDING CASSETTE, SUB-FAMILY A, MEMBER 1    (ATP-BINDING CASSETTE TRANSPORTER 1) (ATP-BINDING CASSETTE    1).//1.30E-63//271aa//47%//P41233-   CTONG20186140-   CTONG20186290//ALDEHYDE DEHYDROGENASE, DIMERIC NADP-PREFERRING (EC    1.2.1.5) (ALDH CLASS 3).//1.50E-74//144aa//100%//P30838-   CTONG20186370//ZINC FINGER PROTEIN 84 (ZINC FINGER PROTEIN    HPF2).//2.60E-52//324aa//33%//P51523-   CTONG20186520//ZINC FINGER PROTEIN    MFG-3.//1.40E-197//643aa//53%//P16374-   CTONG20186550//cca3 protein—rat//2.10E-37//141aa//56%//T31081-   CTONG20188080-   CTONG20189000//PROBABLE GUANINE NUCLEOTIDE REGULATORY PROTEIN TIM    (ONCOGENE TIM) (P60 TIM) (TRANSFORMING IMMORTALIZED MAMMARY    ONCOGENE).//1.10E-48//222aa//50%//Q12774-   CTONG20190290//39.1 KDA PROTEIN IN SURE-CYSC INTERGENIC    REGION.//6.00E-15//132aa//31%//Q57261-   CTONG20190630-   DFNES20016470//Homo sapiens SDP1 protein mRNA, complete    cds.//4.90E-33//95aa//37%//AF076957-   DFNES20018000//CADHERIN-RELATED TUMOR SUPPRESSOR PRECURSOR (FAT    PROTEIN).//8.70E-23//306aa//30%//P33450-   DFNES20025500//Homo sapiens mRNA for paraplegin-like    protein.//3.00E-29//68aa//94%//Y18314-   DFNES20028170//Mouse mRNA for RNA polymerase I associated factor    (PAF53), complete cds.//1.40E-165//393aa//78%//D14336-   DFNES20029660-   DFNES20032550-   DFNES20043710-   DFNES20046840//FORKHEAD BOX PROTEIN E1 (FORKHEAD-RELATED PROTEIN    FKHL15) (THYROID TRANSCRIPTION FACTOR 2)    (TTF-2).//6.20E-05//151aa//32%//000358-   DFNES20055400//Homo sapiens diphthamide biosynthesis protein-2    (DPH2) mRNA, complete cds.//5.40E-203//413aa//91%//AF053003-   DFNES20057660//GRAVE'S DISEASE CARRIER PROTEIN (GDC) (MITOCHONDRIAL    SOLUTE CARRIER PROTEIN HOMOLOG).//7.00E-31//247aa//33%//Q01888-   DFNES20063460//PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT    PAN3 (EC 3.1.13.4) (PAB1P-DEPENDENT    POLY(A)-NUCLEASE).//1.90E-23//115aa//43%//P36102-   DFNES20072990//HYPOTHETICAL 46.7 KDA PROTEIN IN HOR7-COX7 INTERGENIC    REGION.//1.80E-22//310aa//25%//Q04835-   DFNES20073320//Mus musculus RING-finger protein MURF mRNA, complete    cds.//6.70E-118//362aa//61%//AF294790-   DFNES20076340-   DFNES20080880//POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE (EC    2.4.1.41) (PROTEIN-UDP ACETYLGALACTOSAMINYLTRANSFERASE)    (UDP-GALNAC:POLYPEPTIDE, N-ACETYLGALACTOSAMINYLTRANSFERASE)    (GALNAC-T1).//2.00E-104//486aa//43%//Q10472-   DFNES20088810-   DFNES20094820//coronin-like protein [Schizosaccharomyces    pombe]//3.60E-20//333aa//24%//CAB11184-   FCBBF10000230//H. sapiens mRNA from TYL    gene.//3.30E-155//650aa//51%//X99688-   FCBBF10002200-   FCBBF10004760//Homo sapiens GAP-like protein (N61) mRNA, complete    cds.//9.10E-82//412aa//44%//AF251038-   FCBBF20018680//RABPHILIN-3A.//1.70E-16//262aa//30%//P47709-   FCBBF20020440-   FCBBF20021110-   FCBBF20023490//PUTATIVE PRE-mRNA SPLICING FACTOR ATP-DEPENDENT RNA    HELICASE SPAC10F6.02C.//1.20E-90//505aa//39%//042643-   FCBBF20028980-   FCBBF20029280-   FCBBF20032930-   FCBBF20033360//RING CANAL PROTEIN (KELCH    PROTEIN).//7.40E-33//234aa//32%//Q04652-   FCBBF20035430//Mus musculus arsenite inducible RNA associated    protein (Airap) mRNA, complete cds.//1.50E-51//152aa//57%//AF224494-   FCBBF20035490//GAP-associated tyrosine phosphoprotein p62 (Sam68)    [Homo sapiens]>pir∥A38219 GAP-associated tyrosine phosphoprotein    p62//1.50E-214//415aa//93%//NP_(—)006550-   FCBBF20036360-   FCBBF20038230-   FCBBF20038950-   FCBBF20041380-   FCBBF20043730-   FCBBF20054390-   FCBBF20056580//Mus musculus NSD1 protein mRNA, complete    cds.//3.40E-304//773aa//75%//AF064553-   FCBBF20059660-   FCBBF20061310-   FCBBF20066340//Homo sapiens nuclear dual-specificity phosphatase    (SBF1) mRNA, partial cds.//1.20E-68//312aa//49%//U93181-   FCBBF20070800-   FCBBF20070950//MICRONUCLEAR LINKER HISTONE POLYPROTEIN (MIC LH)    [CONTAINS: LINKER HISTONE PROTEINS ALPHA, BETA, DELTA AND    GAMMA].//5.00E-10//601aa//20%//P40631-   FCBBF30000010-   FCBBF30001020-   FCBBF30001100//CRAG protein [Drosophila    melanogaster]//7.40E-185//800aa//46%//CAA76938-   FCBBF30001150-   FCBBF30002270//HISTONE H1′ (H1.0)    (H1(0)).//4.90E-62//154aa//84%//P07305-   FCBBF30002280//THIOREDOXIN PEROXIDASE 2 (THIOREDOXIN-DEPENDENT    PEROXIDE REDUCTASE 2) (PROLIFERATION-ASSOCIATED PROTEIN PAG)    (NATURAL KILLER CELL ENHANCING FACTOR A)    (NKEF-A).//1.20E-27//61aa//98%//Q06830-   FCBBF30002330-   FCBBF30003610//ZINC FINGER PROTEIN 91 (ZINC FINGER PROTEIN HTF10)    (HPF7).//9.10E-93//313aa//53%//Q05481-   FCBBF30004340//Homo sapiens GalNAc-T9 mRNA for    UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, complete    cds.//1.60E-109//299aa//63%//AB040672-   FCBBF30004730-   FCBBF30005180-   FCBBF30005360//Mus musculus spermatogenesis associated factor (SPAF)    mRNA, complete cds.//0//894aa//84%//AF049099-   FCBBF30005500//HYPOTHETICAL PROTEIN    KIAA0167.//5.80E-16//124aa//36%//Q99490-   FCBBF30019140//CHROMODOMAIN HELICASE-DNA-BINDING PROTEIN 3 (CHD-3)    (MI-2 AUTOANTIGEN 240 KDA PROTEIN)    (MI2-ALPHA).//0//725aa//82%//Q12873-   FCBBF30019180//SERINE/THREONINE PROTEIN PHOSPHATASE 2A, 65 KDA    REGULATORY SUBUNIT A, ALPHA ISOFORM (PP2A, SUBUNIT A, PR65-ALPHA    ISOFORM) (PP2A, SUBUNIT A, R1-ALPHA    ISOFORM).//4.60E-233//451aa//98%//P54612-   FCBBF30019240-   FCBBF30021900//ZINC FINGER PROTEIN 91 (ZINC FINGER PROTEIN HTF10)    (HPF7).//4.10E-161//633aa//48%//Q05481-   FCBBF30022680//putative 5′-3′    exonuclease//9.00E-12//200aa//25%//AAG29662-   FCBBF30026580//Homo sapiens retinoblastoma-associated protein RAP140    mRNA, complete cds.//7.60E-27//367aa//28%//AF180425-   FCBBF30029250//GLUCOAMYLASE S1/S2 PRECURSOR (EC 3.2.1.3) (GLUCAN    1,4-ALPHA-GLUCOSIDASE) (1,4-ALPHA-D-GLUCAN    GLUCOHYDROLASE).//4.00E-18//754aa//23%//P08640-   FCBBF30035570-   FCBBF30042610//Homo sapiens CTL2    gene.//2.10E-137//393aa//60%//AJ245621-   FCBBF30048420//TBX19 PROTEIN (T-BOX PROTEIN    19).//1.40E-94//212aa//85%//060806-   FCBBF30053300//Human autoantigen pericentriol material 1 (PCM-1)    mRNA, complete cds.//0//708aa//90%//L27841-   FCBBF30056980-   FCBBF30062490//Mus musculus prominin-like protein mRNA, partial    cds.//7.70E-85//210aa//79%//AF128113-   FCBBF30063990-   FCBBF30068210-   FCBBF30071500//Homo sapiens dentin phosphoryn mRNA, complete    cds.//2.80E-09//675aa//22%//AF094508-   FCBBF30072440//Homo sapiens SARDH mRNA, alternatively spliced,    complete cds.//1.70E-14//81aa//53%//AF095737-   FCBBF30072480-   FCBBF30074530-   FCBBF30074620-   FCBBF30075970-   FCBBF30076310//CAMP-DEPENDENT PROTEIN KINASE, BETA-CATALYTIC SUBUNIT    (EC 2.7.1.37) (PKA C-BETA).//8.20E-166//240aa//100%//P22694-   FCBBF30078600-   FCBBF30079770-   FCBBF30080730//SPLICING FACTOR, ARGININE/SERINE-RICH 7 (SPLICING    FACTOR 9G8).//3.40E-70//136aa//95%//Q16629-   FCBBF30081000-   FCBBF30085560//HYPOTHETICAL 60.3 KDA PROTEIN R13G10.2 IN CHROMOSOME    III.//1.10E-87//531aa//38%//Q21988-   FCBBF30088700-   FCBBF30089380-   FCBBF30091010-   FCBBF30091520//GLUCOAMYLASE S1/S2 PRECURSOR (EC 3.2.1.3) (GLUCAN    1,4-ALPHA-GLUCOSIDASE) (1,4-ALPHA-D-GLUCAN    GLUCOHYDROLASE).//3.70E-09//631aa//21%//P08640-   FCBBF30093170//ZINC FINGER PROTEIN 84 (ZINC FINGER PROTEIN    HPF2).//2.10E-63//173aa//65%//P51523-   FCBBF30095410-   FCBBF30099490-   FCBBF30100080//ARF NUCLEOTIDE-BINDING SITE OPENER (ARNO PROTEIN)    (ARF EXCHANGE FACTOR).//1.10E-57//108aa//100%//Q99418-   FCBBF30100120//Mus musculus semaphorin cytoplasmic domain-associated    protein 3A (Semcap3) mRNA, complete    cds.//2.10E-192//769aa//50%//AF127084-   FCBBF30100410//Mus musculus testis-specific Y-encoded-like protein    (Tspyl1) mRNA, complete cds.//1.90E-56//324aa//42%//AF042180-   FCBBF30101240-   FCBBF30101300-   FCBBF30105080-   FCBBF30105440//Rattus norvegicus ion transporter protein (NRITP)    mRNA, partial cds.//3.40E-36//82aa//91%//AF184921-   FCBBF30105860//microtubule associated-protein orbit [Drosophila    melanogaster].//1.00E-79//556aa//33%//BAA94248-   FCBBF30106950-   FCBBF30107290//MITOCHONDRIAL PROCESSING PEPTIDASE ALPHA SUBUNIT    PRECURSOR (EC 3.4.24.64) (ALPHA-MPP) (P-55) (HA1523)    (KIAA0123).//1.00E-91//172aa//100%//Q10713-   FCBBF30107330-   FCBBF30114180-   FCBBF30114850//Homo sapiens C2H2 (Kruppel-type) zinc finger protein    mRNA, complete cds.//3.20E-24//249aa//34%//AF159567-   FCBBF30115230-   FCBBF30115920//Homo sapiens nolp mRNA, complete    cds.//9.40E-220//257aa//100%//AB017800-   FCBBF30118670//Homo sapiens disintegrin and metalloproteinase domain    19 (ADAM19) mRNA, partial cds.//0//601aa//97%//AF134707-   FCBBF30118890//Drosophila melanogaster La related protein (larp)    mRNA, partial cds.//6.70E-25//221aa//35%//AF221108-   FCBBF30125460-   FCBBF30125880//Homo sapiens single-strand selective monofunctional    uracil DNA glycosylase mRNA, complete    cds.//6.40E-81//96aa//100%//AF125182-   FCBBF30128420-   FCBBF30129010//ZINC FINGER PROTEIN 36 (ZINC FINGER PROTEIN KOX18)    (FRAGMENT).//1.20E-179//322aa//100%//P17029-   FCBBF30130410//CALDESMON (CDM).//3.30E-06//170aa//32%//P12957-   FCBBF30130580-   FCBBF30132050//Homo sapiens mRNA for    UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase.//2.10E-43//253aa//36%//Y15014    FCBBF30132660//Drosophila melanogaster Canton S tartan protein (trn)    mRNA, complete cds.//2.00E-15//293aa//30%//U02078-   FCBBF30135890//GLUTENIN, LOW MOLECULAR WEIGHT SUBUNIT    PRECURSOR.//2.60E-07//163aa//34%//P10385-   FCBBF30136230//NIL-2-A ZINC FINGER PROTEIN (NEGATIVE REGULATOR OF    IL2) (TRANSCRIPTION FACTOR 8).//0//1090aa//94%//P37275-   FCBBF30138000//trg protein—rat//1.30E-82//560aa//37%//160486-   FCBBF30142290//dJ127B20.3 (novel PHD finger protein) [Homo    sapiens].//1.00E-140//287aa//96%//CAB62994-   FCBBF30143550//FYVE FINGER-CONTAINING PHOSPHOINOSITIDE KINASE (EC    2.7.1.68) (1-PHOSPHATIDYLINOSITOL-4-PHOSPHATE KINASE) (PIP5K)    (PTDINS(4)P-5-KINASE) (P235).//0//1027aa//91%//Q9Z1T6-   FCBBF30145670-   FCBBF30151190-   FCBBF30153170//6-PHOSPHOFRUCTOKINASE, LIVER TYPE (EC 2.7.1.11)    (PHOSPHOFRUCTOKINASE 1) (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTO-1-KINASE    ISOZYME B).//0//670aa//99%//P17858-   FCBBF30157270//Rattus norvegicus PAPIN mRNA, complete    cds.//1.20E-179//639aa//58%//AF169411-   FCBBF30161780-   FCBBF30164510//RETINAL-CADHERIN PRECURSOR(R-CADHERIN)    (R-CAD).//0//794aa//98%//P55283-   FCBBF30166220//SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC (EC    2.1.2.1) (SERINE METHYLASE) (GLYCINE HYDROXYMETHYLTRANSFERASE)    (SHMT).//2.70E-12//33aa//100%//P34896-   FCBBF30169280//Petunia x hybrida PGPD14 (PGPD14) mRNA, complete    cds.//1.40E-62//261 aa//42%//AF049930-   FCBBF30169870-   FCBBF30170710-   FCBBF30171230//NEUROENDOCRINE CONVERTASE 2 PRECURSOR (EC 3.4.21.94)    (NEC 2) (PC2) (PROHORMONE CONVERTASE 2) (PROPROTEIN CONVERTASE 2)    (KEX2-LIKE ENDOPROTEASE 2).//1.70E-82//181aa//86%//P16519-   FCBBF30172330-   FCBBF30173960//erythroid differentiation-related factor 1 [Homo    sapiens].//6.00E-32//113aa//100%//AAC0001-   FCBBF30175350//MITOGEN-ACTIVATED PROTEIN KINASE 7 (EC 2.7.1.-)    (EXTRACELLULAR SIGNAL-REGULATED KINASE 5) (ERK5) (ERK4) (BMK1    KINASE).//4.60E-06//245aa//28%//Q13164-   FCBBF30177290//HYPOTHETICAL 47.6 KDA PROTEIN C16C10.5 IN CHROMOSOME    III.//2.40E-28//133aa//46%//Q09251-   FCBBF30179180-   FCBBF30179740-   FCBBF30181730-   FCBBF30194370-   FCBBF30194550//ANKYRIN 1 (ERYTHROCYTE ANKYRIN) (ANKYRIN R) (ANKYRINS    2.1 AND 2.2).//9.90E-54//478aa//33%//P16157-   FCBBF30195690//SYNAPTOTAGMIN I.//1.30E-27//138aa//31%//P34693-   FCBBF30195700-   FCBBF30197840//Mouse mRNA for seizure-related gene product 6 type 2    precursor, complete cds.//0//869aa//91%//D64009-   FCBBF30198670//dof protein—fruit fly (Drosophila    melanogaster)//6.60E-05//272aa//24%//T13712-   FCBBF30201630//Chlamydomonas reinhardtii dhc1 gene for 1-alpha    dynein heavy chain.//1.10E-121//384aa//58%//AJ243806-   FCBBF30212210-   FCBBF30215240//mitogen inducible gene    mig-2—human//2.20E-135//263aa//96%//S69890-   FCBBF30220050//OXYSTEROLS RECEPTOR LXR-BETA (LIVER X RECEPTOR BETA)    (NUCLEAR ORPHAN RECEPTOR LXR-BETA) (UBIQUITOUSLY-EXPRESSED NUCLEAR    RECEPTOR) (NUCLEAR RECEPTOR NER).//6.90E-96//167aa//100%//P55055-   FCBBF30222910//Mus musculus Rap2 interacting protein 8 (RPIP8) mRNA,    complete cds.//4.70E-29//76aa//46%//U73941-   FCBBF30223110-   FCBBF30223210//PLEXIN 4 PRECURSOR (TRANSMEMBRANE PROTEIN    SEX).//1.70E-72//179aa//76%//P51805-   FCBBF30225930-   FCBBF30228940//Homo sapiens zinc finger protein dp mRNA, complete    cds.//2.60E-14//114aa//42%//AF153201-   FCBBF30230610-   FCBBF30236670//Homo sapiens DEAD-box protein abstrakt (ABS) mRNA,    complete cds.//1.00E-128//276aa//91%//AF195417-   FCBBF30250980//GUANINE NUCLEOTIDE-BINDING PROTEIN BETA SUBUNIT-LIKE    PROTEIN.//3.20E-06//190aa//28%//024076-   FCBBF30255680//Rattus norvegicus brain specific cortactin-binding    protein CBP90 mRNA, partial cds.//1.80E-275//641aa//82%//AF053768-   FCBBF30257370//CARNITINE DEFICIENCY-ASSOCIATED PROTEIN EXPRESSED IN    VENTRICLE 1 (CDV-1 PROTEIN).//2.80E-169//355aa//92%//035594-   FCBBF30259050//Mus musculus (clone pMLZ-1) zinc finger protein (Zfp)    mRNA, 3′ end of cds.//1.40E-241//499aa//83%//L36315-   FCBBF30260210//Drosophila melanogaster KISMET-L long isoform (kis)    mRNA, complete cds.//3.90E-178//420aa//68%//AF215703-   FCBBF30260480//Mus musculus putative E1-E2 ATPase mRNA, partial    cds.//1.80E-78//154aa//95%//AF156547-   FCBBF30263080//ZINC FINGER PROTEIN 83 (ZINC FINGER PROTEIN    HPF1).//4.20E-33//107aa//58%//P51522 FCBBF30266510-   FCBBF30271990//ANKYRIN 1 (ERYTHROCYTE    ANKYRIN).//3.00E-43//419aa//33%//Q02357-   FCBBF30275590//dedicator of cyto-kinesis 1 [Homo    sapiens].//1.00E-138//791aa//37%//NP_(—)001371-   FCBBF30282020//cca3 protein—rat//5.50E-249//492aa//94%//T31081-   FCBBF30285930//ZINC FINGER PROTEIN ZFP-1 (MKR1    PROTEIN).//5.70E-68//125aa//97%//P08042-   FCBBF30287940-   FCBBF40000610//late gestation lung 2 protein [Rattus    norvegicus].//5.00E-86//178aa//94%//AAF44721-   FCBBF40001920-   FCBBF40005000-   FCBBF50000410-   FCBBF50000610-   FCBBF50001650//Homo sapiens JP3 mRNA for junctophilin type3,    complete cds.//1.20E-111//407aa//57%//AB042636-   FCBBF50003530//H. sapiens mRNA for dinG    gene.//2.70E-137//181aa//100%//Y10571-   FCBBF50004950-   FEBRA20005040//MYOSIN HEAVY CHAIN, STRIATED    MUSCLE.//1.90E-13//479aa//23%//P24733-   FEBRA20007820//MLN 64 PROTEIN (CAB1    PROTEIN).//7.00E-31//129aa//51%//Q14849-   FEBRA20018670-   FEBRA20026820//ZINC FINGER PROTEIN 91 (ZINC FINGER PROTEIN HTF10)    (HPF7).//2.20E-135//431aa//50%//Q05481-   FEBRA20027070//ZINC FINGER PROTEIN 41    (FRAGMENT).//1.00E-139//333aa//70%//P51814-   FEBRA20029620-   FEBRA20031000//TRICHOHYALIN.//2.20E-16//360aa//26%//P37709-   FEBRA20031150//Homo sapiens HSKM-B (HSKM-B) mRNA, complete    cds.//2.00E-29//63aa//100%//AF226053-   FEBRA20031280-   FEBRA20031810-   FEBRA20035200-   FEBRA20035240//SPLICEOSOME ASSOCIATED PROTEIN 49 (SAP 49)    (SF3B53).//7.30E-05//108aa//31%//Q15427-   FEBRA20038220//GLUCOAMYLASE S1/S2 PRECURSOR (EC 3.2.1.3) (GLUCAN    1,4-ALPHA-GLUCOSIDASE) (1,4-ALPHA-D-GLUCAN    GLUCOHYDROLASE).//7.50E-05//256aa//24%//P08640-   FEBRA20038330-   FEBRA20038970//Homo sapiens mRNA for stabilin-1 (stab1    gene).//1.30E-42//413aa//99%//AJ275213-   FEBRA20039070-   FEBRA20039260//NonF [Streptomyces griseus subsp.    griseus].//2.20E-16//140aa//38%//AAD37457-   FEBRA20040230-   FEBRA20040260-   FEBRA20040290-   FEBRA20040560//Homo sapiens delta-6 fatty acid desaturase (CYB5RP)    mRNA, complete cds.//1.70E-112//204aa//100%//AF134404-   FEBRA20045380//EVI-5 homolog [Homo    sapiens].//7.00E-49//130aa//81%//AAC16031-   FEBRA20046200//ANKYRIN 2 (BRAIN ANKYRIN) (ANKYRIN B) (ANKYRIN,    NONERYTHROID).//1.70E-25//368aa//30%//Q01484-   FEBRA20046280-   FEBRA20046510//ZINC FINGER PROTEIN    135.//1.10E-94//260aa//62%//P52742-   FEBRA20057010//ZINC FINGER PROTEIN 195.//1.30E-12//47aa//70%//014628-   FEBRA20063720//ZINC FINGER PROTEIN 85 (ZINC FINGER PROTEIN HPF4)    (HTF1).//3.10E-243//586aa//73%//Q03923-   FEBRA20076200-   FEBRA20078180-   FEBRA20078800//NADH-UBIQUINONE OXIDOREDUCTASE 20 KDA SUBUNIT    PRECURSOR (EC 1.6.5.3) (EC 1.6.99.3) (COMPLEX I-20 KD) (CI-20KD)    (PSST SUBUNIT).//2.30E-96//192aa//96%//075251-   FEBRA20080860-   FEBRA20082660-   FEBRA20083410-   FEBRA20084750-   FEBRA20086600-   FEBRA20087550//damage-specific DNA binding protein 2 (48 kD) [Homo    sapiens]//1.10E-106//119aa//94%//NP_(—)000098-   FEBRA20088610//CELLULAR RETINALDEHYDE-BINDING PROTEIN    (CRALBP).//2.40E-14//145aa//30%//P10123-   FEBRA20088810//FIBROBLAST GROWTH FACTOR-17 PRECURSOR    (FGF-17).//1.00E-102//193aa//99%//060258-   FEBRA20090160//MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 10 (EC    2.7.1.-) (MIXED LINEAGE KINASE 2) (PROTEIN KINASE    MST).//1.10E-15//111aa//48%//Q02779-   FEBRA20090220//TRANSLATION INITIATION FACTOR EIF-2B EPSILON SUBUNIT    (EIF-2B GDP-GTP EXCHANGE FACTOR).//0//721aa//90%//P47823-   FEBRA20091620-   FEBRA20092760//PINCH PROTEIN (PARTICULARY INTERESTING NEW CYS-HIS    PROTEIN).//2.50E-81//165aa//80%//P48059-   FEBRA20093270-   FEBRA20093280-   FEBRA20095410-   FEBRA20098040-   FEBRA20099860//dynactin 3 (p22); dynactin light chain [Homo    sapiens]//1.70E-41//89aa//100%//NP_(—)009165-   FEBRA20101410-   FEBRA20108020-   FEBRA20108580-   FEBRA20115930-   FEBRA20116650-   FEBRA20121200-   FEBRA20121950//X INACTIVE SPECIFIC TRANSCRIPT PROTEIN    (FRAGMENT).//1.60E-07//155aa//24%//P27571-   FEBRA20141980-   FEBRA20150420//HYPOTHETICAL 131.5 KDA PROTEIN CO₂F12.7 IN CHROMOSOME    X.//6.90E-56//877aa//24%//Q11102-   FEBRA20151750//Mus musculus (clone E5.53) Huntington disease (hdh)    gene, exon 5.//2.60E-12//88aa//43%//L34024-   FEBRA20163980-   FEBRA20170240//ZINC FINGER PROTEIN    75.//7.90E-158//278aa//99%//P51815-   FEBRA20172230//Mus musculus schwannoma-associated protein (SAM9)    mRNA, complete cds.//1.70E-57//295aa//40%//AF026124-   FEBRA20173330//PROTEIN KINASE CLK3 (EC    2.7.1.-).//4.80E-277//490aa//99%//P49761-   FEBRA20175020-   FEBRA20175330-   FEBRA20177800//RNA binding motif protein 9 [Homo    sapiens].//4.00E-09//75aa//95%//NP_(—)055124-   FEBRA20180510-   FEBRA20182030-   FEBRA20187460-   FEBRA20191720//REGULATOR OF G-PROTEIN SIGNALING 11    (RGS11).//2.00E-73//104aa//100%//094810-   HCHON10000150//SKELETAL MUSCLE LIM-PROTEIN 1 (SLIM 1) (SLIM) (FOUR    AND A HALF LIM DOMAINS PROTEIN 1)    (FHL-1).//4.10E-74//154aa//84%//Q13642-   HCHON10001660-   HCHON20000870//SERINE/THREONINE-PROTEIN KINASE CTR1 (EC    2.7.1.37).//2.10E-21//300aa//26%//Q05609-   HCHON20002650//EARLY GROWTH RESPONSE PROTEIN 2 (EGR-2) (KROX-20    PROTEIN).//9.90E-05//166aa//26%//P51774-   HCHON20002710//UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 13 (EC    3.1.2.15) (UBIQUITIN THIOLESTERASE 13) (UBIQUITIN-SPECIFIC    PROCESSING PROTEASE 13) (DEUBIQUITINATING ENZYME    13).//7.40E-10//114aa//28%//P38187-   HCHON20015050//LEUKOCYTE ADHESION GLYCOPROTEIN P150, 95 ALPHA CHAIN    PRECURSOR (LEUKOCYTE ADHESION RECEPTOR P150, 95) (CD11C) (LEU M5)    (INTEGRIN ALPHA-X).//8.60E-06//250aa//26%//P20702-   HEART10001420//Mus musculus skm-BOP1 (Bop) mRNA, complete    cds.//6.10E-259//485aa//94%//U76373-   HEART10001490//ACTIN INTERACTING PROTEIN    2.//1.80E-71//243aa//58%//P46681-   HEART20009590//Homo sapiens mRNA for paraplegin-like    protein.//7.10E-47//145aa//67%//Y18314-   HEART20019310//Mus musculus RING-finger protein MURF mRNA, complete    cds.//6.70E-118//362aa//61%//AF294790-   HEART20022200//METHIONINE AMINOPEPTIDASE 2 (EC 3.4.11.18) (METAP 2)    (PEPTIDASE M 2) (INITIATION FACTOR 2 ASSOCIATED 67 KDA GLYCOPROTEIN)    (P67).//1.50E-209//447aa//86%//P50579-   HEART20031680-   HEART20047640//CALCIUM/CALMODULIN-DEPENDENT 3′,5′-CYCLIC NUCLEOTIDE    PHOSPHODIESTERASE 1C (EC 3.1.4.17) (CAM-PDE    1C).//0//769aa//94%//Q63421-   HEART20063100//H. sapiens mRNA histone RNA hairpin-binding    protein.//5.60E-114//212aa//100%//Z71188-   HEART20082570//AMINOMETHYLTRANSFERASE PRECURSOR (EC 2.1.2.10)    (GLYCINE CLEAVAGE SYSTEM T PROTEIN).//5.50E-113//210aa//69%//P28337-   HHDPC10001140-   HHDPC20051850//STEROID RECEPTOR PROTEIN    DG6.//9.50E-43//101aa//89%//015173-   HHDPC20081230//NUCLEOLIN (PROTEIN C23).//0//681aa//92%//P19338-   HHDPC20082790-   HHDPC20082970-   HHDPC20088160-   HLUNG20008460//DIAPHANOUS PROTEIN HOMOLOG    2.//7.60E-33//521aa//26%//060879-   HLUNG20009260-   HLUNG20009550-   HLUNG20010130-   HLUNG20011260//TYROSINE-PROTEIN KINASE SRC-1 (EC 2.7.1.112)    (P60-SRC-1).//1.10E-46//92aa//100%//P13115-   HLUNG20011440-   HLUNG20011460//Rattus norvegicus serine-arginine-rich splicing    regulatory protein SRRP86 mRNA, complete    cds.//1.20E-159//398aa//79%//AF234765-   HLUNG20012140-   HLUNG20014590//ZINC FINGER PROTEIN    135.//1.20E-122//350aa//59%//P52742-   HLUNG20015070//SLIT PROTEIN PRECURSOR.//5.00E-14//167aa//33%//P24014-   HLUNG20015180//BALBIANI RING PROTEIN 3    PRECURSOR.//8.80E-08//444aa//24%//Q03376-   HLUNG20020500-   HLUNG20020850//TLM PROTEIN (TLM    ONCOGENE).//5.00E-17//91aa//54%//P17408-   HLUNG20021450-   HLUNG20023030-   HLUNG20024050-   HLUNG20025620-   HLUNG20028110//zinc finger protein—fission yeast    (Schizosaccharomyces pombe).//2.70E-23//140aa//38%//T39456-   HLUNG20029420-   HLUNG20029490-   HLUNG20030420//Mus musculus mRNA for MAIL, complete    cds.//1.00E-164//728aa//68%//AB020974-   HLUNG20030490//Ambystoma tigrinum RPE65 protein mRNA, complete    cds.//1.70E-64//335aa//42%//AF047465-   HLUNG20030610-   HLUNG20031620-   HLUNG20032460//LYSOSOMAL PRO-X CARBOXYPEPTIDASE PRECURSOR (EC    3.4.16.2) (PROLYLCARBOXYPEPTIDASE) (PRCP) (PROLINE CARBOXYPEPTIDASE)    (ANGIOTENSINASE C) (LYSOSOMAL CARBOXYPEPTIDASE    C).//8.60E-274//440aa//99%//P42785-   HLUNG20033060//Homo sapiens GAP-like protein (N61) mRNA, complete    cds.//1.20E-81//389aa//45%//AF251038-   HLUNG20033310-   HLUNG20033350-   HLUNG20034970-   HLUNG20037140-   HLUNG20037160//RETROVIRUS-RELATED ENV    POLYPROTEIN.//1.90E-131//439aa//54%//P10267-   HLUNG20037780-   HLUNG20038330-   HLUNG20041540//GLUCOAMYLASE S1/S2 PRECURSOR (EC 3.2.1.3) (GLUCAN    1,4-ALPHA-GLUCOSIDASE) (1,4-ALPHA-D-GLUCAN    GLUCOHYDROLASE).//8.80E-08//286aa//24%//P08640-   HLUNG20041590//ubiquitous tetratricopeptide containing protein RoXaN    [Homo sapiens].//1.00E-158//737aa//42%//AAF05541-   HLUNG20042730//CYTOCHROME P450 4A4 (EC 1.14.14.1) (CYPIVA4)    (PROSTAGLANDIN OMEGA-HYDROXYLASE)    (P450-P-2).//4.90E-126//442aa//49%//P10611-   HLUNG20045340//MOB2 PROTEIN (MPS1 BINDER    2).//4.60E-27//135aa//37%//P43563-   HLUNG20047070-   HLUNG20050760-   HLUNG20051330-   HLUNG20052300//AIG1 PROTEIN.//3.00E-23//216aa//30%//P54120-   HLUNG20054790//PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT (EC    2.7.1.137) (IB PI3-KINASE P101 SUBUNIT) (PTDINS-3-KINASE P101)    (PI3K) (P101-P13K).//8.30E-22//292aa//25%//002696-   HLUNG20055240-   HLUNG20056560-   HLUNG20057380-   HLUNG20059240-   HLUNG20060670-   HLUNG20063700//H. sapiens PEBP2aC1 acute myeloid leukaemia    mRNA.//3.60E-22//62aa//79%//Z35278-   HLUNG20065700-   HLUNG20065990//SYNTAXIN 4.//8.80E-127//267aa//96%//Q12846-   HLUNG20067810-   HLUNG20068120//NUCLEAR TRANSITION PROTEIN 2    (TP-2).//7.10E-06//86aa//38%//P11101-   HLUNG20069350//CALCYPHOSINE.//1.80E-13//128aa//31%//Q13938-   HLUNG20070410-   HLUNG20072100//Gallus gallus Dach2 protein (Dach2) mRNA, complete    cds.//1.40E-236//404aa//79%//AF198349-   HLUNG20072190-   HLUNG20072450-   HLUNG20074330-   HLUNG20079310-   HLUNG20081390//DNAJ PROTEIN.//1.60E-17//98aa//47%//P35515-   HLUNG20081530//NEUROFILAMENT TRIPLET H PROTEIN (200 KDA    NEUROFILAMENT PROTEIN) (NF-H).//1.90E-09//220aa//25%//P12036-   HLUNG20082350//Homo sapiens goodpasture antigen-binding protein    (COL4A3BP) mRNA, complete cds.//0//399aa//93%//AF136450-   HLUNG20083330//alpha1 (III) collagen [Homo    sapiens]//5.40E-61//113aa//99%//CAA29886-   HLUNG20083480//Chicken mRNA for TSC-22 variant, complete cds, clone    SLFEST52.//9.00E-178//527aa//68%//D82364-   HLUNG20083840-   HLUNG20083960-   HLUNG20084790//HYPOTHETICAL 65.2 KDA TRP-ASP REPEATS CONTAINING    PROTEIN D2030.9 IN CHROMOSOME I.//5.50E-47//161aa//53%//P90794-   HLUNG20085210//Homo sapiens intersectin 2 (SH3D1B) mRNA, complete    cds.//9.60E-28//62aa//95%//AF248540-   HLUNG20088750-   HLUNG20092530-   HLUNG20093030-   HLUNG20094130-   KIDNE20011600-   KIDNE20016360//Rattus norvegicus potassium channel (erg2) mRNA,    complete cds.//0//418aa//96%//AF016192-   KIDNE20024380-   KIDNE20027980-   KIDNE20080690//PROBABLE AMINOTRANSFERASE T01B11.2 (EC    2.6.1.-).//5.80E-114//445aa//48%//P91408-   KIDNE20081170//Homo sapiens microtubule-based motor (HsKIFC3) mRNA,    complete cds.//6.20E-153//216aa//99%//AF004426-   KIDNE20083150-   KIDNE20083620//L-ASPARAGINASE (EC 3.5.1.1) (L-ASPARAGINE    AMIDOHYDROLASE).//2.60E-53//148aa//43%//Q9ZSD6-   KIDNE20084030-   KIDNE20084040//PHOSPHOLIPASE D1 (EC 3.1.4.4) (PLD 1) (CHOLINE    PHOSPHATASE 1) (PHOSPHATIDYLCHOLINE-HYDROLYZING PHOSPHOLIPASE    D1).//3.30E-70//134aa//100%//Q13393-   KIDNE20084730//Homo sapiens FH1/FH2 domain-containing protein FHOS    (FHOS) mRNA, complete cds.//2.60E-148//599aa//52%//AF113615-   KIDNE20084800-   KIDNE20086490-   KIDNE20086660-   KIDNE20086970-   KIDNE20087880-   KIDNE20088240//atopy related autoantigen CALC [Homo    sapiens].//1.00E-26//300aa//26%//CAA76830-   KIDNE20089870//HISTONE ACETYLTRANSFERASE TYPE B SUBUNIT 2    (RETINOBLASTOMA BINDING PROTEIN P46) (RETINOBLASTOMA-BINDING PROTEIN    7).//4.30E-237//422aa//99%//Q16576-   KIDNE20091090-   KIDNE20094260-   KIDNE20094670//Drosophila melanogaster AAA family protein Bor (bor)    mRNA, complete cds.//2.10E-124//399aa//59%//AF227209-   KIDNE20095530-   KIDNE20133460//Homo sapiens mRNA for sperm    protein.//3.40E-146//284aa//100%//X91879-   KIDNE20133880-   KIDNE20134130-   KIDNE20134890//CENTROMERIC PROTEIN E (CENP-E    PROTEIN).//7.70E-05//169aa//21%//Q02224-   KIDNE20137310-   KIDNE20138450-   KIDNE20140870//zinc finger protein 106 [Mus    musculus]//2.10E-288//822aa//67%//AF060246-   KIDNE20141120-   KIDNE20141700//40S RIBOSOMAL PROTEIN S4, X ISOFORM (SINGLE COPY    ABUNDANT mRNA PROTEIN) (SCR10).//2.60E-72//153aa//89%//P12750-   KIDNE20142680-   KIDNE20142900//THROMBOMODULIN PRECURSOR (FETOMODULIN) (TM) (CD141    ANTIGEN).//1.80E-71//119aa//100%//P07204-   KIDNE20143200-   KIDNE20147170//acetylglutamate synthase—fission yeast    (Schizosaccharomyces pombe)//8.40E-15//143aa//37%//T40666-   KIDNE20148080-   KIDNE20149780//NG28 [Mus musculus]//3.50E-66//367aa//44%//AAC97966-   KIDNE20150730//REGULATOR OF MITOTIC SPINDLE ASSEMBLY 1    (RMSA-1).//2.40E-06//84aa//41%//P49646-   KIDNE20152440//Homo sapiens mRNA for serin protease with IGF-binding    motif, complete cds.//1.80E-181//388aa//93%//D87258-   KIDNE20154330//Rattus norvegicus mRNA for multi PDZ domain    protein.//0//763aa//87%//AJ001320-   KIDNE20154830-   KIDNE20155980-   KIDNE20157100-   KIDNE20160360//ARF NUCLEOTIDE-BINDING SITE OPENER (ARNO PROTEIN)    (ARF EXCHANGE FACTOR).//7.10E-40//194aa//41%//Q99418-   KIDNE20160960-   KIDNE20163710-   KIDNE20165390//Homo sapiens mRNA for beta-tubulin folding cofactor    D.//0//709aa//94%//AJ006417-   KIDNE20169180//UROMODULIN PRECURSOR (TAMM-HORSFALL URINARY    GLYCOPROTEIN) (THP).//0//615aa//99%//P07911-   KIDNE20170400-   KIDNE20173150//Bos taurus mRNA for mitochondrial aralkyl    acylCoA:amino acid    N-acyltransferase.//2.90E-53//277aa//40%//AJ223301-   KIDNE20173430//Homo sapiens PDZ domain containing-protein (PDZK1)    mRNA, complete cds.//7.90E-28//150aa//34%//AF012281-   KIDNE20176030-   KIDNE20181670-   KIDNE20182540-   KIDNE20186170//UDP-GLUCURONOSYLTRANSFERASE 2B13 PRECURSOR,    MICROSOMAL (EC 2.4.1.17) (UDPGT)    (EGT10).//4.40E-38//214aa//39%//P36512-   KIDNE20188630-   KIDNE20189890//Homo sapiens mRNA for KARP-1-binding protein 2    (KAB2), complete cds.//6.00E-30//177aa//44%//AB022658-   KIDNE20189960//TREHALASE PRECURSOR (EC 3.2.1.28)    (ALPHA,ALPHA-TREHALASE) (ALPHA,ALPHA-TREHALOSE    GLUCOHYDROLASE).//1.40E-224//421aa//97%//043280-   KIDNE20191870-   LIVER20006260//Mus musculus zinc finger protein ZFP113 mRNA,    complete cds.//4.50E-183//385aa//85%//AF167320-   LIVER20007690-   LIVER20007750-   LIVER20010510-   LIVER20010760//Homo sapiens C-type lectin-like receptor-1 mRNA,    complete cds.//3.10E-134//208aa//100%//AF200949-   LIVER20010990//Rattus norvegicus mRNA for putative integral membrane    transport protein (UST1r).//7.00E-52//196aa//54%//Y09945-   LIVER20011640//Human proline rich calmodulin-dependent protein    kinase mRNA, complete cds.//2.00E-116//221aa//97%//U23460-   LIVER20013890-   LIVER20026440//CYTOCHROME P450 4F3 (EC 1.14.13.30) (CYPIVF3)    (LEUKOTRIENE-B4 OMEGA-HYDROXYLASE) (LEUKOTRIENE-B4 20-MONOOXYGENASE)    (CYTOCHROME P450-LTB-OMEGA).//2.60E-136//295aa//84%//Q08477-   LIVER20030650//WHITE PROTEIN.//7.20E-09//229aa//25%//Q05360-   LIVER20032340-   LIVER20038000//MITOCHONDRIAL CARNITINE/ACYLCARNITINE CARRIER PROTEIN    (CARNITINE/ACYLCARNITINE TRANSLOCASE)    (CAC).//9.40E-40//148aa//38%//P97521-   LIVER20040740//RETINAL-BINDING PROTEIN    (RALBP).//3.10E-60//337aa//37%//P49193-   LIVER20055270//SELENIDE, WATER DIKINASE 2 (EC 2.7.9.3)    (SELENOPHOSPHATE SYNTHETASE 2) (SELENIUM DONOR PROTEIN    2).//2.70E-204//376aa//97%//Q99611-   MESAN20006200//ANNEXIN II (LIPOCORTIN II) (CALPACTIN I HEAVY CHAIN)    (CHROMOBINDIN 8) (P36) (PROTEIN I) (PLACENTAL ANTICOAGULANT    PROTEIN IV) (PAP-IV).//1.70E-84//174aa//95%//P07355-   MESAN20007110-   MESAN20008150-   MESAN20008940-   MESAN20009090//Homo sapiens CEGP1 protein (CEGP1),    mRNA//1.10E-179//553aa//58%//NM_(—)020974-   MESAN20016270//ZINC FINGER PROTEIN 37A (ZINC FINGER PROTEIN KOX21)    (FRAGMENT).//1.60E-141//242aa//100%//P17032-   MESAN20021130//Human SH3 domain-containing proline-rich kinase    (sprk) mRNA, complete cds.//8.20E-168//346aa//91%//U07747    MESAN20021220//INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN COMPLEX    ACID LABILE CHAIN PRECURSOR (ALS).//7.40E-26//197aa//30%//002833-   MESAN20021470//SPINDLIN (30000 MR METAPHASE COMPLEX) (SSEC    P).//3.50E-123//229aa//98%//Q61142-   MESAN20021860-   MESAN20026870-   MESAN20027240//Rho guanine nucleotide exchange factor (GEF) 10 [Homo    sapiens].//1.00E-134//620aa//40%//NP_(—)055444-   MESAN20027900//COLLAGEN ALPHA 3(VI) CHAIN    PRECURSOR//0//1001aa//98%//P12111-   MESAN20029780-   MESAN20030350//Mus musculus diaphanous-related formin (Dia2) mRNA,    complete cds.//6.60E-301//669aa//84%//AF094519-   MESAN20030370-   MESAN20030390-   MESAN20033220//ALDEHYDE DEHYDROGENASE 7 (EC    1.2.1.5).//1.60E-24//54aa//100%//P43353-   MESAN20034440//39.1 KDA PROTEIN IN SURE-CYSC INTERGENIC    REGION.//2.70E-07//117aa//31%//Q57261-   MESAN20038520//DNA-DIRECTED RNA POLYMERASE III 128 KDA POLYPEPTIDE    (EC 2.7.7.6) (RNA POLYMERASE III SUBUNIT 2).//0//831aa//70%//P25167-   MESAN20041380-   MESAN20045750-   MESAN20056890//SPLICING FACTOR, ARGININE/SERINE-RICH 2 (SPLICING    FACTOR SC35) (SC-35) (SPLICING COMPONENT, 35 KDA) (PR264    PROTEIN).//3.30E-12//97aa//48%//Q01130-   MESAN20057240//DNA EXCISION REPAIR PROTEIN    ERCC-1.//5.90E-120//195aa//98%//P07992-   MESAN20058110//65 KDA FK506-BINDING PROTEIN PRECURSOR (EC 5.2.1.8)    (FKBP65) (FKBPRP) (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE) (PPIASE)    (ROTAMASE) (IMMUNOPHILIN FKBP65).//8.00E-117//229aa//89%//Q61576-   MESAN20059570//Rattus norvegicus mRNA for seven transmembrane    receptor, complete cds.//1.00E-173//484aa//63%//BAA82518-   MESAN20060220-   MESAN20060430-   MESAN20065990//Human protein serine/threonine kinase stk2 mRNA,    complete cds.//2.40E-07//65aa//50%//L20321-   MESAN20067430//TROPOMYOSIN, FIBROBLAST ISOFORM    TM3.//1.80E-39//87aa//100%//P09494-   MESAN20069530//LIM domain only 7 isoform c [Homo    sapiens]//2.20E-286//545aa//99%//NP_(—)056667-   MESAN20084150//Mus musculus secretory carrier membrane protein 4    mRNA, complete cds.//2.20E-48//128aa//72%//AF224721-   MESAN20085360-   MESAN20089260-   MESAN20090190//CEGP1 protein [Homo    sapiens].//0//880aa//57%//NP_(—)066025-   MESAN20094180-   MESAN20095220-   MESAN20095800//PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 10 (EC 5.2.1.8)    (PPIASE) (ROTAMASE) (CYCLOPHILIN-10).//1.60E-31//150aa//46%//P52017-   NESOP20004520//LYMPHOCYTE-SPECIFIC PROTEIN LSP1 (PP52 PROTEIN) (52    KDA PHOSPHOPROTEIN) (LYMPHOCYTE-SPECIFIC ANTIGEN    WP34).//3.40E-173//321aa//99%//P33241-   NESOP20005040-   NT2NE20018740-   NT2NE20018890//Homo sapiens WD-repeat protein 6 (WDR6) mRNA,    complete cds.//6.60E-184//257aa//99%//AF099100-   NT2NE20021860//Lytechinus variegatus embryonic blastocoelar    extracellular matrix protein precursor (ECM3) mRNA, complete    cds.//9.00E-68//466aa//36%//AF287478-   NT2NE20026200//TRANSKETOLASE (EC 2.2.1.1)    (TK).//1.80E-160//310aa//99%//P29401-   NT2NE20026510//basic protein, cytosolic—fruit fly (Drosophila    melanogaster)//6.10E-35//202aa//41%//S47857-   NT2NE20028700-   NT2NE20033150-   NT2NE20037050//U2 SMALL NUCLEAR RIBONUCLEOPROTEIN AUXILIARY FACTOR    35 KDA SUBUNIT RELATED-PROTEIN 2.//7.20E-08//109aa//38%//Q15696-   NT2NE20038870//ZINC FINGER X-LINKED PROTEIN ZXDA    (FRAGMENT).//5.90E-153//405aa//72%//P98168-   NT2NE20039210-   NT2NE20042550//ADENYLATE KINASE, CHLOROPLAST (EC 2.7.4.3) (ATP-AMP    TRANSPHOSPHORYLASE).//7.80E-15//153aa//28%//P43188-   NT2NE20045190-   NT2NE20047870-   NT2NE20053230-   NT2NE20053950//ZINC FINGER PROTEIN    136.//6.40E-108//284aa//64%//P52737-   NT2NE20059210-   NT2NE20059680//Homo sapiens integrin cytoplasmic domain associated    protein (Icap-1a) mRNA, complete    cds.//1.80E-44//96aa//100%//AF012023-   NT2NE20060750//ZINC FINGER PROTEIN ZFP-36    (FRAGMENT).//1.20E-69//198aa//68%//P16415-   NT2NE20061030//ZINC FINGER PROTEIN    165.//3.00E-39//125aa//65%//P49910-   NT2NE20062880-   NT2NE20064780//A-AGGLUTININ ATTACHMENT SUBUNIT    PRECURSOR.//4.10E-05//443aa//24%//P32323-   NT2NE20066590-   NT2NE20069580-   NT2NE20070520-   NT2NE20073650-   NT2NE20077250//Homo sapiens cell cycle progression 2 protein (CPR2)    mRNA, complete cds.//1.20E-173//349aa//94%//AF011792-   NT2NE20077270-   NT2NE20077860-   NT2NE20079670//ZINC FINGER PROTEIN 84 (ZINC FINGER PROTEIN    HPF2).//2.60E-98//345aa//47%//P51523-   NT2NE20080770-   NT2NE20082130-   NT2NE20082600//Homo sapiens zinc finger protein dp mRNA, complete    cds.//2.10E-19//163aa//42%//AF153201-   NT2NE20086070-   NT2NE20087270//Homo sapiens putative RNA binding protein mRNA,    alternatively spliced, complete cds.//4.30E-14//221aa//29%//AF119121-   NT2NE20087850//ANTER-SPECIFIC PROLINE-RICH PROTEIN APG (PROTEIN CEX)    (FRAGMENT).//1.80E-08//75aa//40%//P40603-   NT2NE20088030-   NT2NE20092950-   NT2NE20095230//Homo sapiens HSKM-B (HSKM-B) mRNA, complete    cds.//1.40E-09//112aa//32%//AF226053-   NT2NE20104000-   NT2NE20107810-   NT2NE20108420//KES1 PROTEIN.//4.70E-25//312aa//31%//P35844-   NT2NE20111190//C-TERMINAL BINDING PROTEIN    2.//9.00E-54//137aa//84%//P56545-   NT2NE20112210-   NT2NE20114850-   NT2NE20117580//NADH-UBIQUINONE OXIDOREDUCTASE 20 KDA SUBUNIT    PRECURSOR (EC 1.6.5.3) (EC 1.6.99.3) (COMPLEX I-20 KD) (CI-20 KD)    (PSST SUBUNIT).//1.20E-76//153aa//95%//075251-   NT2NE20119980//TUMOR NECROSIS FACTOR, ALPHA-INDUCED PROTEIN 1,    ENDOTHELIAL (B12 PROTEIN).//6.10E-48//135aa//74%//Q13829-   NT2NE20123610-   NT2NE20124570-   NT2NE20126030-   NT2NE20127900//Homo sapiens myo-inositol 1-phosphate synthase A1    (ISYNA1) mRNA, complete cds.//1.40E-269//465aa//99%//AF220530-   NT2NE20140130//SEMAPHORIN 3B PRECURSOR (SEMAPHORIN V) (SEMA    V).//1.90E-42//90aa//100%//Q13214-   NT2NE20140280-   NT2NE20141040//DOWN SYNDROME CRITICAL REGION PROTEIN    1.//1.80E-105//197aa//99%//P53805-   NT2NE20145250//SCG10 PROTEIN (SUPERIOR CERVICAL GANGLION-10    PROTEIN).//2.50E-58//141aa//88%//P55821-   NT2NE20146510//HYPOTHETICAL 104.7 KDA PROTEIN F23F12.8 IN CHROMOSOME    III PRECURSOR.//6.20E-08//179aa//23%//P46504-   NT2NE20148690-   NT2NE20149500-   NT2NE20150610-   NT2NE20152620-   NT2NE20153620//mitogen inducible gene    mig-2—human//7.90E-147//449aa//63%//S69890-   NT2NE20155650//RETROVIRUS-RELATED ENV    POLYPROTEIN.//2.30E-29//114aa//33%//P10267-   NT2NE20157120-   NT2NE20165190-   NT2NE20167660//Mus musculus nuclear localization signal binding    protein (spot-1) mRNA, complete cds.//3.50E-09//76aa//40%//S79410-   NT2NE20173970//Rattus norvegicus beta-catenin binding protein mRNA,    complete cds.//1.60E-24//134aa//46%//AF169825-   NT2NE20177210//Leishmania major partial ppg1 gene for    proteophosphoglycan.//1.10E-06//169aa//27%//AJ243460-   NT2NE20181760-   NT2NE20181800-   NT2NE20184720-   NT2RI20016240-   NT2RI20021200-   NT2RI20033920-   NT2RI20093010//BIFUNCTIONAL METHYLENETETRAHYDROFOLATE    DEHYDROGENASE/CYCLOHYDROLASE, MITOCHONDRIAL PRECURSOR [INCLUDES:    NAD-DEPENDENT METHYLENETETRAHYDROFOLATE DEHYDROGENASE (EC 1.5.1.15);    METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE (EC    3.5.4.9)].//5.90E-34//86aa//81%//P13995-   NT2RP70001120//GA BINDING PROTEIN BETA-1 CHAIN (GABP-BETA-1 SUBUNIT)    (GABPB1).//2.50E-113//384aa//62%//Q00420-   NT2RP70001730//Mus musculus actin-binding protein (ENC-1) mRNA,    complete cds.//4.30E-249//589aa//74%//U65079-   NT2RP70003110//ELASTIN PRECURSOR    (TROPOELASTIN).//1.40E-165//613aa//61%//P15502-   NT2RP70012830//CALPHOTIN.//7.90E-17//445aa//28%//Q02910-   NT2RP70022820-   NT2RP70027190//RAS SUPPRESSOR PROTEIN 1 (RSU-1) (RSP-1 PROTEIN)    (RSP-1).//3.80E-23//186aa//34%//Q01730-   NT2RP70029780//ZINC FINGER PROTEIN ZFP-36    (FRAGMENT).//4.30E-118//381aa//56%//P16415-   NT2RP70030840//Mus musculus schlafen3 (Slfn3) mRNA, complete    cds.//3.70E-55//328aa//33%//AF099974-   NT2RP70031070//36 KDA NUCLEOLAR PROTEIN HNP36 (DELAYED-EARLY    RESPONSE PROTEIN 12) (DER12).//1.20E-23//169aa//34%//Q61672-   NT2RP70031340-   NT2RP70031480-   NT2RP70035110//Caenorhabditis elegans UNC-89 (unc-89) gene, complete    cds.//1.50E-07//229aa//26%//U33058-   NT2RP70046410//BASONUCLIN.//3.60E-71//318aa//43%//Q01954-   NT2RP70049610-   NT2RP70056290-   NT2RP70056690//F-SPONDIN PRECURSOR.//2.20E-15//366aa//24%//P35447-   NT2RP70057500//Hypothetical zinc finger-like protein [Homo    sapiens].//0//799aa//94%//AAF88107-   NT2RP70064570//CALPAIN P94, LARGE [CATALYTIC] SUBUNIT (EC 3.4.22.17)    (CALCIUM-ACTIVATED NEUTRAL PROTEINASE) (CANP) (P94 PROTEIN)    (MUSCLE-SPECIFIC CALCIUM-ACTIVATED NEUTRAL PROTEASE 3 LARGE    SUBUNIT).//9.40E-86//278aa//40%//Q64691-   NT2RP70074800-   NT2RP70075300//ZINC FINGER PROTEIN 211 (ZINC FINGER PROTEIN    C2H2-25).//9.60E-121//333aa//63%//Q13398-   NT2RP70075800//HYPOTHETICAL 43.1 KDA TRP-ASP REPEATS CONTAINING    PROTEIN K04G11.4 IN CHROMOSOME X.//1.80E-13//244aa//25%//Q93847-   NT2RP70080150-   NT2RP70084540-   NT2RP70087140//SKIN SECRETORY PROTEIN XP2 PRECURSOR (APEG    PROTEIN).//1.40E-11//264aa//31%//P17437-   NT2RP70090870//ZINC FINGER PROTEIN 91 (ZINC FINGER PROTEIN HTF10)    (HPF7).//4.20E-230//592aa//61%//Q05481-   NTONG20002230//Mus musculus RW1 protein mRNA, complete    cds.//5.20E-97//546aa//34%//AF060565-   NTONG20005310-   NTONG20017620-   NTONG20029850//CALCYPHOSINE (R2D5    ANTIGEN).//1.60E-24//183aa//32%//P41150-   NTONG20031580//heat shock 27 kD protein family, member 7    (cardiovascular); cardiovascular heat shock protein [Homo    sapiens]//6.10E-69//141aa//95%//NP_(—)055239-   NTONG20032100//KERATIN, TYPE I CYTOSKELETAL 13 (CYTOKERATIN 13)    (K13) (CK 13).//4.20E-175//351aa//96%//P13646-   NTONG20034540//CGMP-DEPENDENT 3′,5′-CYCLIC PHOSPHODIESTERASE (EC    3.1.4.17) (CYCLIC GMP STIMULATED PHOSPHODIESTERASE)    (CGS-PDE).//0//713aa//99%//000408-   NTONG20035150//RING CANAL PROTEIN (KELCH    PROTEIN).//9.10E-30//570aa//25%//Q04652-   NTONG20043080//MYOSIN LIGHT CHAIN KINASE, SMOOTH MUSCLE AND    NON-MUSCLE ISOZYMES (EC 2.7.1.117) (MLCK) [CONTAINS:    TELOKIN].//4.30E-12//226aa//28%//P11799-   NTONG20048440//P116 RHO-INTERACTING PROTEIN (P116RIP)    (RIP3).//1.60E-269//588aa//87%//P97434-   NTONG20049180-   NTONG20053630//GLUCOAMYLASE S1/S2 PRECURSOR (EC 3.2.1.3) (GLUCAN    1,4-ALPHA-GLUCOSIDASE) (1,4-ALPHA-D-GLUCAN    GLUCOHYDROLASE).//1.30E-12//247aa//29%//P08640-   NTONG20053730//UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 64E (EC    3.1.2.15) (UBIQUITIN THIOLESTERASE 64E) (UBIQUITIN-SPECIFIC    PROCESSING PROTEASE 64E) (DEUBIQUITINATING ENZYME    64E).//8.70E-104//340aa//60%//Q24574-   NTONG20053910//Bos taurus differentiation enhancing factor 1 (DEF-1)    mRNA, complete cds.//2.50E-198//891aa//45%//AF112886-   NTONG20055200//ELONGATION FACTOR G, MITOCHONDRIAL PRECURSOR    (MEF-G).//1.10E-269//522aa//83%//Q07803-   NTONG20058010//ACETYL-COENZYME A SYNTHETASE (EC 6.2.1.1)    (ACETATE-COA LIGASE) (ACYL-ACTIVATING    ENZYME).//3.90E-124//398aa//54%//068040-   NTONG20058220//Homo sapiens phosphoprotein pp75 mRNA, partial    cds.//8.60E-14//349aa//25%//AF153085-   OCBBF20000740//Homo sapiens mRNA for ISLR, complete    cds.//3.60E-87//287aa//59%//AB003184-   OCBBF20001780-   OCBBF20005220//Rattus norvegicus Fos-related antigen mRNA, complete    cds.//3.40E-233//552aa//84%//U34932-   OCBBF20009820-   OCBBF20011860//Mus musculus epithelial protein lost in neoplasm-a    (Eplin) mRNA, complete cds.//4.30E-33//98aa//66%//AF307844-   OCBBF20012520//Homo sapiens mRNA for ISLR, complete    cds.//6.50E-88//287aa//59%//AB003184-   OCBBF20016390-   OCBBF20016810//enhancer of polycomb [Mus    musculus]//0//743aa//92%//AF079765-   OCBBF20109450-   OCBBF20109780-   OCBBF20110210//KILON PROTEIN PRECURSOR (KINDRED OF    IGLON).//4.30E-182//352aa//94%//Q9Z0J8-   OCBBF20110730-   OCBBF20111370//BCL2/ADENOVIRUS E1B 19-KDA PROTEIN-INTERACTING    PROTEIN 2.//5.70E-84//324aa//52%//054940-   OCBBF20111600//69 KDA ISLET CELL AUTOANTIGEN (ICA69) (ISLET CELL    AUTOANTIGEN 1).//1.30E-113//335aa//57%//Q05084-   OCBBF20112280//Mesembryanthemum crystallinum    phosphoenolpyruvate/phosphate translocator precursor (PPT) mRNA,    complete cds.//7.00E-09//113aa//30%//AF223359-   OCBBF20112320-   OCBBF20113110-   OCBBF20115360-   OCBBF20116250//Mus musculus C2H2-type zinc finger protein (Evi9)    mRNA, complete cds.//0//592aa//99%//AF051525-   OCBBF20117220-   OCBBF20118720-   OCBBF20119810-   OCBBF20120010//Homo sapiens zinc metalloprotease ADAMTS6 (ADAMTS6)    mRNA, complete cds.//1.60E-44//217aa//42%//AF140674-   OCBBF20120950//ZINC FINGER PROTEIN 151 (POLYOMAVIRUS LATE INITIATOR    PROMOTER BINDING PROTEIN) (LP-1) (ZINC FINGER PROTEIN    Z13).//1.00E-28//201aa//34%//Q60821-   OCBBF20121910//LAF-4 PROTEIN (LYMPHOID NUCLEAR    PROTEIN).//0//740aa//98%//P51826-   OCBBF20123200-   OCBBF20142290-   OCBBF20147070-   OCBBF20152330-   OCBBF20155030-   OCBBF20156450//ZINC FINGER PROTEIN    75.//8.20E-163//289aa//99%//P51815-   OCBBF20157970//ZINC FINGER PROTEIN    135.//2.80E-98//306aa//56%//P52742-   OCBBF20160380//liver stage antigen LSA-1—Plasmodium    falciparum//1.10E-21//938aa//24%//A45592-   OCBBF20165900//CELL SURFACE ANTIGEN 114/A10    PRECURSOR.//4.80E-09//145aa//31%//P19467-   OCBBF20165910//Mus musculus pecanex 1 mRNA, complete    cds.//4.20E-116//407aa//53%//AF096286-   OCBBF20166890//RESTIN (CYTOPLASMIC LINKER PROTEIN-170)    (CLIP-170).//4.20E-21//124aa//45%//042184-   OCBBF20166900//ZINC FINGER PROTEIN CLONE 647    (FRAGMENT).//9.00E-18//196aa//30%//P15622-   OCBBF20167290//probable acyl-CoA dehydrogenase—Deinococcus    radiodurans (strain R1)//2.50E-72//222aa//60%//D75616-   OCBBF20170350//Mus musculus mRNA for GATS    protein.//2.50E-56//121aa//96%//AJ296173-   OCBBF20174580//G2/MITOTIC-SPECIFIC CYCLIN S13-7 (B-LIKE CYCLIN)    (FRAGMENT).//7.10E-16//240aa//25%//P25012-   OCBBF20174890//ankyrin 3, long splice    form—human//1.10E-150//178aa//100%//A55575-   OCBBF20175360//Homo sapiens C2H2 (Kruppel-type) zinc finger protein    mRNA, complete cds.//3.80E-11//101aa//36%//AF159567-   OCBBF20176650-   OCBBF20177540//ZINC FINGER PROTEIN MLZ-4 (ZINC FINGER PROTEIN    46).//1.40E-110//223aa//86%//Q03309-   OCBBF20177910-   OCBBF20182060//Mesocricetus auratus guanine nucleotide-binding    protein beta 5 (Gnb5) mRNA, complete    cds.//7.20E-82//265aa//61%//U13152-   OCBBF20185630-   OCBBF20188280-   OCBBF20191950//VERY LOW-DENSITY LIPOPROTEIN RECEPTOR PRECURSOR (VLDL    RECEPTOR).//0//720aa//97%//P98155-   PANCR10000860//ELASTASE IIIB PRECURSOR (EC 3.4.21.70) (PROTEASE    E).//1.10E-52//87aa//97%//P08861-   PEBLM10001470//glutamine (Q)-rich factor 1, QRF-1 [mice, B-cell    leukemia, BCL1, Peptide Partial, 84    aa]//5.00E-42//84aa//98%//AAB29272-   PEBLM20001800//IG ALPHA-1 CHAIN C    REGION.//7.90E-197//353aa//100%//P01876-   PEBLM20003260//ZINC FINGER PROTEIN 83 (ZINC FINGER PROTEIN    HPF1).//4.90E-62//151aa//70%//P51522 PEBLM20005020-   PLACE50001290//HYPOTHETICAL 87.9 KDA PROTEIN F44G4.1 IN CHROMOSOME    II PRECURSOR.//2.90E-16//102aa//43%//P54073-   PLACE50001390-   PLACE60001910-   PLACE60004260//CYSTATIN M PRECURSOR (CYSTATIN    E).//1.50E-37//81aa//97%//Q15828-   PLACE60006300-   PLACE60011180-   PLACE60012620//LYSOSOMAL TRAFFICKING REGULATOR (BEIGE    HOMOLOG).//8.40E-14//128aa//38%//Q99698-   PLACE60017120-   PLACE60052940//TRANSCRIPTION REGULATORY PROTEIN    GAL11.//1.70E-05//445aa//23%//P32257-   PLACE60053280-   PLACE60054230//DIAPHANOUS PROTEIN HOMOLOG    2.//1.00E-35//385aa//26%//060879-   PLACE60054820//HYPOTHETICAL PROTEIN    KIAA0032.//1.20E-50//180aa//61%//Q15034-   PLACE60054870//MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B (CELLULAR MYOSIN    HEAVY CHAIN, TYPE B) (NMMHC-B).//3.70E-11//434aa//20%//P35580-   PLACE60055350-   PLACE60055460//Homo sapiens leucine-zipper protein FKSG13 (FKSG13)    mRNA, complete cds.//5.40E-164//327aa//99%//AF312393-   PLACE60055590//MYOSIN-BINDING PROTEIN H (MYBP-H) (H-PROTEIN) (86 KDA    PROTEIN).//1.30E-05//124aa//35%//Q05623-   PLACE60056910-   PLACE60057860-   PLACE60061370-   PLACE60062660//ADP-ribosylation factor binding protein GGA1;    ADP-ribosylation factor binding protein; Golgi-associated,    gamma-adaptin ear containing, ARF-binding protein 1 [Homo    sapiens].//6.00E-84//249aa//93%//NP_(—)037497-   PLACE60062870-   PLACE60063940-   PLACE60064180//PUTATIVE PRE-mRNA SPLICING FACTOR ATP-DEPENDENT RNA    HELICASE.//1.90E-51//368aa//37%//022899-   PLACE60064740//ADHESIVE PLAQUE MATRIX PROTEIN PRECURSOR (FOOT    PROTEIN 1) (MCFP1).//4.80E-11//157aa//31%//Q25434-   PLACE60066970//ZINC FINGER PROTEIN    191.//1.30E-36//115aa//48%//014754-   PLACE60068710//SUPPRESSOR PROTEIN    SRP40.//9.50E-43//238aa//50%//P32583-   PLACE60069880-   PLACE60070500-   PLACE60071800//CORONIN-LIKE PROTEIN    P57.//3.80E-60//108aa//81%//Q92176-   PLACE60072390-   PLACE60072420-   PLACE60073090//Homo sapiens myo-inositol 1-phosphate synthase A1    (ISYNA1) mRNA, complete cds.//6.60E-219//362aa//98%//AF220530-   PLACE60074820-   PLACE60077870-   PLACE60080360//mucin [Homo sapiens]//5.50E-05//164aa//30%//CAA84032-   PLACE60081260-   PLACE60082850-   PLACE60087680//INSULIN-LIKE GROWTH. FACTOR BINDING PROTEIN 3    PRECURSOR (IGFBP-3) (IBP-3) (IGF-BINDING PROTEIN    3).//2.30E-103//255aa//79%//P17936-   PLACE60088240-   PLACE60092280-   PLACE60092370-   PLACE60093380-   PLACE60095240-   PLACE60095600//HYPOTHETICAL HELICASE C28H8.3 IN CHROMOSOME    III.//2.70E-28//201aa//38%//Q09475-   PLACE60098350//Human hepatocellular carcinoma associated protein    (JCL-1) mRNA, complete cds.//5.20E-285//558aa//97%//U92544-   PLACE60104630//macrophage migration inhibitory factor    (glycosylation-inhibiting factor) [Homo    sapiens]//9.70E-51//10aa//93%//XP_(—)000858-   PLACE60105680//Homo sapiens mRNA for TU12B1-TY, complete    cds.//1.70E-30//65aa//64%//AB032773-   PLACE60107010//SUPPRESSOR PROTEIN    SRP40.//3.80E-05//117aa//29%//P32583-   PLACE60109910-   PLACE60113340//BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE    PROTEOGLYCAN CORE PROTEIN PRECURSOR(HSPG) (PERLECAN)    (PLC).//5.90E-65//238aa//32%//Q05793-   PLACE60118810//Rattus norvegicus kinesin light chain KLCt mRNA,    complete cds.//1.90E-230//504aa//87%//AF166267-   PLACE60119700//Homo sapiens mRNA for ABP32, complete    cds.//2.30E-21//47aa//100%//AB018357-   PLACE60120280//SER/THR-RICH PROTEIN T10 IN DGCR    REGION.//6.00E-99//126aa//84%//P54797-   PLACE60122970//novel C2H2 type zinc finger    protein//5.60E-84//169aa//98%//CAC10457-   PLACE60132200//TRICHIOHYALIN.//3.10E-47//297aa//47%//P37709-   PLACE60132320-   PLACE60132880-   PLACE60138840//PUTATIVE MITOCHONDRIAL CARRIER PROTEIN    PET8.//7.40E-59//274aa//47%//P38921-   PLACE60140640//Homo sapiens nucleotide binding protein (NBP) mRNA,    complete cds.//3.90E-138//262aa//99%//AF208536-   PLACE60150510//NUCLEAR PROTEIN SNF7.//1.60E-11//189aa//25%//P39929-   PLACE60154450//PUTATIVE PREOPTIC REGULATORY FACTOR-2 PRECURSOR    (PORF-2).//7.30E-36//75aa//98%//P18890-   PLACE60155910-   PLACE60157310-   PLACE60162100-   PLACE60175640-   PLACE60177880//IGSF5 [Homo    sapiens].//3.60E-174//315aa//99%//CAB90447-   PLACE60177910-   PLACE60181870-   PLACE60184410//Mus musculus peroxisomal long chain acyl-CoA    thioesterase Ib (Pte1b) gene, exon 3 and complete    cds.//1.00E-43//126aa//69%//AF180801-   PLACE60184870//PHOSPHOLIPID TRANSFER PROTEIN PRECURSOR (LIPID    TRANSFER PROTEIN II).//1.50E-227//330aa//99%//P55058-   PLACE60188630//Mus musculus mRNA for    acetylglucosaminyltransferase-like    protein.//7.80E-08//317aa//23%//AJ006278-   PROST10001100//Zea mays clone AGPZm1 arabinogalactan protein (agp)    mRNA, partial cds.//5.80E-05//180aa//32%//AF134579-   PROST10001360-   PROST10002150-   PROST20007170//Hypothetical Kruppel-Type Zinc Finger Protein    (R28830_(—)1)//0//432aa//100%//AAC24608-   PROST20007600//PUTATIVE ENDONUCLEASE C1F12.06C (EC    3.1.-.-).//5.90E-29//134aa//44%//Q10348-   PROST20011160-   PROST20011800-   PROST20014140-   PROST20014150-   PROST20014650-   PROST20015210//MYOSIN HEAVY CHAIN, SMOOTH MUSCLE ISOFORM (SMMHC)    (FRAGMENT).//3.00E-107//262aa//85%//P35749-   PROST20015400-   PROST20016760//M-PHASE PHOSPHOPROTEIN 8    (FRAGMENT).//9.00E-157//298aa//99%//Q99549-   PROST20022120-   PROST20024250//ZINC FINGER PROTEIN    136.//1.70E-45//128aa//63%//P52737-   PROST20028970//Oryctolagus cuniculus CARP mRNA, complete    cds.//4.80E-44//177aa//51%//AF131883-   PROST20033240//EPHRIN TYPE-A RECEPTOR 6 PRECURSOR (EC 2.7.1.112)    (TYROSINE-PROTEIN KINASE RECEPTOR EHK-2) (EPH HOMOLOGY    KINASE-2).//8.40E-241//441aa//95%//Q62413-   PROST20035170//Homo sapiens zinc finger protein dp mRNA, complete    cds.//3.40E-15//128aa//42%//AF153201-   PROST20035830-   PROST20036280-   PROST20036350//MULTIFUNCTIONAL AMINOACYL-TRNA SYNTHETASE [INCLUDES:    GLUTAMYL-TRNA SYNTHETASE (EC 6.1.1.17) (GLUTAMATE-TRNA LIGASE);    PROLYL-TRNA SYNTHETASE (EC 6.1.1.15) (PROLINE-TRNA    LIGASE)].//2.20E-137//651aa//42%//P07814-   PROST20039300//Bos taurus mitochondrial mRNA for    xenobiotic/medium-chain fatty acid:CoA ligase form    XL-III.//1.60E-68//180aa//68%//AJ132751-   PROST20041460-   PROST20042700-   PROST20045700//Zea mays clone AGPZm1 arabinogalactan protein (agp)    mRNA, partial cds.//5.80E-05//180aa//32%//AF134579-   PROST20047440-   PROST20048170-   PROST20050390//CYTOCHROME P450 2J2 (EC 1.14.14.1) (CYPIIJ2)    (ARACHIDONIC ACID EPOXYGENASE).//1.40E-34//188aa//42%//P51589-   PROST20051310//Homo sapiens DEAD-box protein abstrakt (ABS) mRNA,    complete cds.//8.50E-134//257aa//99%//AF195417-   PROST20052720-   PROST20052850//CYCLIN G-ASSOCIATED KINASE (EC    2.7.1.-).//2.20E-18//107aa//54%//P97874-   PROST20054660-   PROST20058860//SMALL NUCLEAR RIBONUCLEOPROTEIN ASSOCIATED PROTEINS B    AND B′ (SNRNP-B) (SM PROTEIN B/B′)    (SM-B/SM-B′).//8.20E-05//134aa//33%//P14678-   PROST20060200-   PROST20062820//TRANSLATION INITIATION FACTOR    IF-2.//1.50E-07//102aa//41%//P71613-   PROST20063430//BCL2/ADENOVIRUS E1B 19-KDA PROTEIN-INTERACTING    PROTEIN 2.//8.50E-74//305aa//46%//Q12982-   PROST20065100-   PROST20065790//6-PHOSPHOFRUCTOKINASE, TYPE C (EC 2.7.1.11)    (PHOSPHOFRUCTOKINASE 1) (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTO-1-KINASE    ISOZYME C) (6-PHOSPHOFRUCTOKINASE, PLATELET    TYPE).//0//697aa//99%//Q01813-   PROST20073280-   PROST20075280//MYOSIN LIGHT CHAIN KINASE, SMOOTH MUSCLE AND    NON-MUSCLE ISOZYMES (EC 2.7.1.117) (MLCK) [CONTAINS:    TELOKIN].//1.30E-08//245aa//23%//P11799-   PROST20078710-   PROST20082430-   PROST20084470//Plasmodium berghei strain NYU2 merozoite surface    protein-1 mRNA, partial cds.//2.50E-08//122aa//28%//AF000413-   PROST20084680-   PROST20084720//CYTOCHROME P450 4F2 (EC 1.14.13.30) (CYPIVF2)    (LEUKOTRIENE-B4 OMEGA-HYDROXYLASE) (LEUKOTRIENE-B4 20-MONOOXYGENASE)    (CYTOCHROME P450-LTB-OMEGA).//1.50E-37//85aa//85%//P78329-   PROST20087240-   PROST20093470-   PROST20094000-   PROST20097310-   PROST20097360-   PROST20097840//SYNAPSIN I.//1.80E-09//193aa//34%//P17599-   PROST20099090//ADAM 12 PRECURSOR (EC 3.4.24.-) (A DISINTEGRIN AND    METALLOPROTEINASE DOMAIN 12) (MELTRIN    ALPHA).//1.90E-22//73aa//60%//043184-   PROST20102190//CALMODULIN.//1.30E-20//98aa//47%//P02594-   PROST20102500-   PROST20103820-   PROST20105450//SODIUM/HYDROGEN EXCHANGER 6 (NA(+)/H(+) EXCHANGER 6)    (NHE-6) (KIAA0267).//1.60E-96//214aa//75%//Q92581-   PROST20106060-   PROST20108850//MICROSOMAL SIGNAL PEPTIDASE 23 KDA SUBUNIT (EC    3.4.-.-) (SPC22/23).//1.20E-69//132aa//100%//P12280-   PROST20110120-   PROST20114100-   PROST20120070//KINESIN HEAVY CHAIN (UBIQUITOUS KINESIN HEAVY CHAIN)    (UKHC).//5.00E-05//286aa//24%//P33176-   PROST20121570-   PROST20122490//Gallus gallus syndesmos mRNA, complete    cds.//1.20E-63//139aa//84%//AF095446-   PROST20124000-   PROST20125420-   PROST20127450//Homo sapiens TSC-22 related protein (TSC-22R) mRNA,    complete cds.//7.90E-44//95aa//98%//AF153603-   PROST20130320-   PROST20138730-   PROST20146590//MUCIN 1 PRECURSOR (POLYMORPHIC EPITHELIAL MUCIN)    (PEM) (PEMT) (EPISIALIN) (TUMOR-ASSOCIATED MUCIN)    (CARCINOMA-ASSOCIATED MUCIN) (TUMOR-ASSOCIATED EPITHELIAL MEMBRANE    ANTIGEN) (EMA) (H23AG) (PEANUT-REACTIVE URINARY MUCIN) (PUM) (BREAST    CARCINOMA-ASSOCIATED ANTIGEN DF3).//3.50E-08//556aa//23%//P15941-   PROST20151370//Human probable zinc finger protein H101 mRNA, partial    cds.//1.60E-11//104aa//41%//U81557-   PROST20152510//UDP-N-ACETYLGLUCOSAMINE-PEPTIDE    N-ACETYLGLUCOSAMINYLTRANSFERASE 100 KDA SUBUNIT (EC 2.4.1.-)    (O-GLCNAC TRANSFERASE P100 SUBUNIT).//6.00E-17//148aa//34%//015294-   PROST20152870//Homo sapiens APC2 gene, exon    14.//1.60E-05//195aa//30%//AJ131187 PROST20155370//ZINC FINGER    PROTEIN 38 (ZFP-38) (CTFIN51) (TRANSCRIPTION FACTOR    RU49).//1.10E-72//140aa//55%//Q07231-   PROST20156360-   PROST20159320-   PROST20168600//Homo sapiens six transmembrane epithelial antigen of    prostate (STEAP1) mRNA, complete    cds.//1.20E-70//237aa//54%//AF186249-   PUAEN10000650//Homo sapiens TSC-22 related protein (TSC-22R) mRNA,    complete cds.//7.90E-44//95aa//98%//AF153603-   PUAEN10000870-   PUAEN10001640//Mus musculus cerebellar postnatal development    protein-1 (Cpd1) mRNA, partial cds.//2.80E-126//270aa//90%//U89345-   PUAEN20000800-   PUAEN20001520//L-A VIRUS GAG PROTEIN N-ACETYLTRANSFERASE (EC    2.3.1.-).//1.70E-34//145aa//51%//Q03503-   PUAEN20002470//PROTEIN MOV-10.//6.30E-102//405aa//44%//P23249-   PUAEN20003120//ENHANCER OF ZESTE HOMOLOG 2    (ENX-1).//0//643aa//97%//Q15910-   SALGL10001070//CH-TOG PROTEIN (COLONIC AND HEPATIC TUMOR    OVER-EXPRESSED PROTEIN) (KIAA0097).//5.30E-150//297aa//96%//Q14008-   SKMUS20006790-   SKMUS20007260//MICROTUBULE-ASSOCIATED PROTEIN 1B (MAP1.2) (MAP1(X))    [CONTAINS: MAP1 LIGHT CHAIN LC1].//8.10E-05//396aa//23%//P14873-   SKMUS20008730//smoothelin large isoform L2 [Homo    sapiens].//1.20E-221//217aa//98%//AAF01481-   SKMUS20017400//TROPOMYOSIN ALPHA CHAIN, SKELETAL MUSCLE    TYPE.//3.20E-97//242aa//81%//P06753-   SKMUS20020770-   SKMUS20026340-   SKMUS20040440//60S RIBOSOMAL PROTEIN L3 (HIV-1 TAR RNA BINDING    PROTEIN B) (TARBP-B).//3.60E-189//229aa//99%//P39023-   SKMUS20064810-   SKMUS20073150//20-HYDROXYECDYSONE PROTEIN PRECURSOR    (20-HE).//1.50E-05//129aa//32%//P29681-   SKMUS20073590//tropomodulin 4 (muscle) [Homo    sapiens]//3.90E-58//115aa//100%//NP_(—)037485-   SKMUS20079150//splicing factor 3a, subunit 3, 60 kD; pre-mRNA    splicing factor SF3a (60 kD), similar to S. cerevisiae PRP9    (spliceosome-associated protein 61) [Homo    sapiens]//9.10E-13//65aa//60%//NP_(—)006793-   SKMUS20091900-   SKNMC10001230//CYCLIN-DEPENDENT KINASE 4 INHIBITOR A (CDK4I)    (P16-INK4) (P16-INK4A) (TUMOR SUPPRESSOR    CDKN2A).//1.60E-08//105aa//38%//077617-   SKNMC20006350//65 KDA FK506-BINDING PROTEIN PRECURSOR (EC 5.2.1.8)    (FKBP65) (FKBPRP) (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE) (PPIASE)    (ROTAMASE) (IMMUNOPHILIN FKBP65).//1.10E-185//419aa//79%//Q61576-   SKNSH10001010-   SKNSH20007160-   SKNSH20009710//TROPOMYOSIN, CYTOSKELETAL TYPE    (TM30-NM).//3.20E-74//174aa//86%//P12324-   SKNSH20030640//SPLICEOSOME ASSOCIATED PROTEIN 62 (SAP 62)    (SF3A66).//3.00E-06//127aa//33%//Q62203-   SKNSH20040390-   SKNSH20052400//VEGETATIBLE INCOMPATIBILITY PROTEIN    HET-E-1.//3.60E-17//175aa//29%//Q00808-   SKNSH20057920//CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE I    (EC 2.7.1.123) (CAM KINASE I).//5.00E-37//197aa//40%//Q14012-   SKNSH20068220-   SKNSH20094350-   SMINT20000070//Mus musculus mRNA for granuphilin-b, complete    cds.//2.70E-44//128aa//41%//AB025259-   SMINT20002320//SERINE/THREONINE PROTEIN PHOSPHATASE 2A, 56 KDA    REGULATORY SUBUNIT, BETA ISOFORM (PP2A, B SUBUNIT, B′ BETA ISOFORM)    (PP2A, B SUBUNIT, B56 BETA ISOFORM) (PP2A, B SUBUNIT, PR61 BETA    ISOFORM) (PP2A, B SUBUNIT, R5 BETA    ISOFORM).//4.70E-160//299aa//100%//Q15173-   SMINT20006020//faciogenital dysplasia protein 2 [Mus    musculus]//4.10E-158//327aa//87%//AF017368-   SMINT20006090//Oryctolagus cuniculus mRNA for parchorin, complete    cds.//7.50E-87//175aa//93%//AB035520-   SMINT20007470//TRICHOHYALIN.//1.20E-37//492aa//28%//Q07283-   SMINT20008110//CALCIUM-TRANSPORTING ATPASE 2C1 (EC 3.6.1.38)    (ATP-DEPENDENT CA2+ PUMP PMR1).//1.20E-50//165aa//63%//P98194-   SMINT20011830-   SMINT20011950//ZINC FINGER PROTEIN    202.//1.90E-67//426aa//40%//095125-   SMINT20012220-   SMINT20013970-   SMINT20014610-   SMINT20016150//FERRITIN LIGHT CHAIN (FERRITIN L    SUBUNIT).//3.50E-91//174aa//100%//P02792-   SMINT20017310-   SMINT20021260-   SMINT20023110-   SMINT20024140//IG KAPPA CHAIN V-IV REGION B17    PRECURSOR.//1.20E-60//134aa//87%//P06314-   SMINT20026200//ENL PROTEIN.//1.10E-05//260aa//24%//Q03111-   SMINT20028800//tumor supressor protein—fruit fly (Drosophila    melanogaster).//2.00E-78//493aa//34%//T13797-   SMINT20028840//CMRF35 ANTIGEN    PRECURSOR.//8.40E-19//136aa//41%//Q08708-   SMINT20030740//ZINC FINGER PROTEIN    136.//4.50E-194//535aa//63%//P52737-   SMINT20031280-   SMINT20035050//GTPASE ACTIVATING PROTEIN    BEM2/IPL2.//1.20E-07//134aa//26%//P39960-   SMINT20035510//Drosophila melanogaster La related protein (larp)    mRNA, partial cds.//5.40E-39//334aa//30%//AF221108-   SMINT20036440//Drosophila melanogaster epsin-like protein mRNA,    complete cds./12.90E-69//446aa//41%//AF233291-   SMINT20038660//Homo sapiens HNOEL-iso (HNOEL-iso) mRNA, complete    cds.//5.60E-201//368aa//99%//AF201945-   SMINT20039050//Homo sapiens TRIAD3 mRNA, partial    cds.//3.20E-86//156aa//100%//AF228527-   SMINT20043390-   SMINT20044140//ZINC FINGER PROTEIN 84 (ZINC FINGER PROTEIN    HPF2).//3.50E-39//440aa//28%//P51523-   SMINT20044730//UBIQUINONE BIOSYNTHESIS PROTEIN    AARF.//6.20E-22//272aa//27%//P27854-   SMINT20045470-   SMINT20045830-   SMINT20045890-   SMINT20047290-   SMINT20048720-   SMINT20049920//CYTOSOLIC PURINE 5′-NUCLEOTIDASE (EC    3.1.3.5).//4.10E-39//132aa//57%//P49902-   SMINT20052130//Rattus norvegicus mRNA for gankyrin homologue,    complete cds.//9.20E-07//104aa//33%//AB022014-   SMINT20054050//ABC1 PROTEIN HOMOLOG    PRECURSOR.//1.40E-98//467aa//45%//Q92338-   SMINT20056230//Ig mu chain precursor, membrane-bound (clone    201)—human//5.60E-233//422aa//78%//S14683-   SMINT20056240-   SMINT20062050//PLECTIN.//7.50E-17//436aa//25%//P30427-   SMINT20067080-   SMINT20070620-   SMINT20074330//tektin A1 [Strongylocentrotus    purpuratus]//3.10E-26//125aa//45%//M97188-   SMINT20077920-   SMINT20077960//GELSOLIN PRECURSOR, PLASMA (ACTIN-DEPOLYMERIZING    FACTOR) (ADF) (BREVIN) (AGEL).//3.30E-246//459aa//99%//P06396-   SMINT20081330-   SMINT20083290//IG ALPHA-1 CHAIN C    REGION.//4.40E-196//352aa//99%//P01876-   SMINT20084910-   SMINT20085310-   SMINT20085450-   SMINT20086250//GLYCINE CLEAVAGE SYSTEM H PROTEIN    PRECURSOR.//2.20E-40//70aa//97%//P23434-   SMINT20086720//ZINC FINGER PROTEIN    191.//1.40E-29//109aa//55%//014754-   SMINT20088440//IG KAPPA CHAIN V-II REGION RPMI 6410    PRECURSOR.//5.10E-44//117aa//78%//P06310-   SMINT20088690-   SMINT20089210-   SMINT20089600//Homo sapiens mRNA for PICK1, complete    cds.//3.10E-145//278aa//100%//AB026491-   SMINT20091190//IG ALPHA-1 CHAIN C    REGION.//3.70E-198//353aa//99%//P01876-   SMINT20092120-   SMINT20092160-   SMINT20093630-   SMINT20094150-   SMINT20094680//Homo sapiens mawbp mRNA for MAWD binding protein,    complete cds.//2.80E-50//77aa//100%//AB049758-   SPLEN20005160-   SPLEN20005370-   SPLEN20006950-   SPLEN20011350-   SPLEN20012450-   SPLEN20015030-   SPLEN20015100//HYPOTHETICAL 72.5 KDA PROTEIN C2F7.10 IN CHROMOSOME    I.//7.50E-16//121aa//36%//Q09701-   SPLEN20016500-   SPLEN20017610-   SPLEN20017810-   SPLEN20019120-   SPLEN20020530-   SPLEN20023430-   SPLEN20023540//H. sapiens mRNA for F25B3.3 kinase like protein    from C. elegans.//1.50E-205//385aa//99%//Y12336-   SPLEN20023850//DNA REPAIR PROTEIN    RAD18.//3.00E-56//469aa//30%//P53692-   SPLEN20024190//EGF-containing fibulin-like extracellular matrix    protein 1; fibrillin-like [Homo    sapiens]//3.70E-192//327aa//99%//NP_(—)061489-   SPLEN20024510-   SPLEN20024620//Homo sapiens mRNA for acetyl LDL receptor, complete    cds.//1.00E-217//401aa//100%//D86864-   SPLEN20024770//Rattus norvegicus (rsec6) mRNA, complete    cds.//2.10E-88//545aa//31%//U32575-   SPLEN20024930//Rattus norvegicus PIPP mRNA for proline-rich inositol    polyphosphate 5-phosphatase, complete cds.//0//639aa//91%//AB032551-   SPLEN20029170-   SPLEN20036780-   SPLEN20039180//TENSIN.//2.70E-135//341aa//65%//Q04205-   SPLEN20040780//CORNIFIN B (SMALL PROLINE-RICH PROTEIN 1B) (SPR1B)    (SPR1 B).//5.10E-12//110aa//37%//Q62267-   SPLEN20041810//BC-2 protein [Homo    sapiens]//4.00E-24//59aa//96%//AF042384-   SPLEN20042200//TRANSCRIPTIONAL REPRESSOR    CTCF.//8.40E-22//127aa//33%//P49711-   SPLEN20043430-   SPLEN20043460-   SPLEN20043680//DNA-REPAIR PROTEIN COMPLEMENTING XP-D CELLS    (XERODERMA PIGMENTOSUM GROUP D COMPLEMENTING PROTEIN) (DNA EXCISION    REPAIR PROTEIN ERCC-2).//7.30E-171//325aa//99%//P18074-   SPLEN20045550-   SPLEN20048800//Homo sapiens mRNA for N-Acetylglucosamine    kinase.//1.90E-51//104aa//100%//AJ242910-   SPLEN20049840//M. musculus mRNA for myosin    I.//0//1093aa//89%//X97650-   SPLEN20050090//TRICHOHYALIN.//7.20E-17//554aa//23%//P37709-   SPLEN20051420-   SPLEN20054160//Dof protein [Drosophila    melanogaster]//9.60E-14//222aa//29%//AJ010641-   SPLEN20054500//Homo sapiens mRNA for putative    dipeptidase.//7.10E-130//244aa//100%//AJ295149-   SPLEN20055600//ZINC FINGER PROTEIN 46 (ZINC FINGER PROTEIN    KUP).//3.00E-56//155aa//63%//P24278-   SPLEN20057830//REGULATOR OF MITOTIC SPINDLE ASSEMBLY 1    (RMSA-1).//1.10E-16//139aa//43%//P49646-   SPLEN20057900//Homo sapiens N-acetylglucosamine-1-phosphodiester    alpha-N-acetylglucosaminidase mRNA, complete    cds.//9.00E-75//130aa//93%//AF187072-   SPLEN20058180-   SPLEN20059270//ZINC-FINGER PROTEIN RFP (RET FINGER    PROTEIN).//7.20E-61//497aa//31%//P14373-   SPLEN20062830-   SPLEN20063250//zinc finger protein nocA—fruit fly (Drosophila    melanogaster)//9.00E-16//364aa//30%//A55929-   SPLEN20063890//FIBROMODULIN PRECURSOR (FM) (COLLAGEN-BINDING 59 KDA    PROTEIN).//2.60E-118//242aa//94%//Q06828-   SPLEN20067010-   SPLEN20071820//Homo sapiens DNA polymerase mu (Pol mu) mRNA,    complete cds.//4.70E-62//116aa//100%//AF176097-   SPLEN20073500//TUMOR NECROSIS FACTOR, ALPHA-INDUCED PROTEIN 2 (B94    PROTEIN).//3.50E-10//463aa//25%//Q03169-   SPLEN20073880-   SPLEN20076190-   SPLEN20076470//KINESIN LIGHT CHAIN    (KLC).//2.40E-18//137aa//38%//P46825-   SPLEN20080070//TISSUE ALPHA-L-FUCOSIDASE PRECURSOR (EC 3.2.1.51)    (ALPHA-L-FUCOSIDASE I) (ALPHA-L-FUCOSIDE    FUCOHYDROLASE).//4.70E-253//359aa//98%//P04066-   SPLEN20081640-   SPLEN20085910//Homo sapiens protein activator of the    interferon-induced protein kinase (PACT) mRNA, complete    cds.//2.90E-23//52aa//100%//AF072860-   SPLEN20087370-   SPLEN20087860-   SPLEN20090880//HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-24(A-9)    ALPHA CHAIN PRECURSOR (AW-24).//1.40E-66//153aa//83%//P05534-   SPLEN20098030//TRANSCRIPTION INTERMEDIARY FACTOR 1-BETA (NUCLEAR    COREPRESSOR KAP-1) (KRAB-ASSOCIATED PROTEIN    1).//4.00E-18//267aa//26%//Q13263-   SPLEN20100040//258.1 KDA PROTEIN C210RF5    (KIAA0933).//7.90E-46//223aa//43%//Q9Y3R5-   SPLEN20101950//SODIUM/HYDROGEN EXCHANGER 6 (NA(+)/H(+) EXCHANGER 6)    (NHE-6) (KIAA0267).//7.70E-112//353aa//61%//Q92581-   SPLEN20104150-   SPLEN20104690-   SPLEN20105100-   SPLEN20108000//Homo sapiens steroid dehydrogenase homolog mRNA,    complete cds.//9.30E-73//155aa//94%//AF078850-   SPLEN20108460-   SPLEN20110180//Homo sapiens golgi membrane protein GP73 mRNA,    complete cds.//1.60E-162//347aa//91%//AF236056-   SPLEN20110210-   SPLEN20110860-   SPLEN20111450-   SPLEN20114190-   SPLEN20116720//Homo sapiens misato mRNA, partial    cds.//1.00E-277//481aa//89%//AF272833-   SPLEN20117580-   SPLEN20118050//BONE/CARTILAGE PROTEOGLYCAN I PRECURSOR (BIGLYCAN)    (PG-S1).//1.00E-123//240aa//97%//P21810-   SPLEN20121790-   SPLEN20125230-   SPLEN20126110-   SPLEN20135030//Homo sapiens PDZ-LIM protein mystique mRNA, complete    cds.//3.30E-92//178aa//97%//AY007729-   SPLEN20136700-   SPLEN20136730//Homo sapiens RAB-like protein 2A (RABL2A) mRNA,    complete cds.//9.30E-41//102aa//90%//AF095350-   SPLEN20137530-   SPLEN20138600//NUMB protein [Homo    sapiens].//1.00E-97//102aa//100%//AAD01548-   SPLEN20139100//Human (hybridoma H210) anti-hepatitis A IgG variable    region, constant region, complementarity-determining regions mRNA,    complete cds.//2.30E-227//490aa//85%//M87789-   SPLEN20139360//MAJOR CENTROMERE AUTOANTIGEN B (CENTROMERE PROTEIN B)    (CENP-B).//5.10E-35//295aa//32%//P07199-   SPLEN20175920-   SPLEN20176130//Homo sapiens mRNA for ALEX1, complete    cds.//9.90E-21//161aa//32%//AB039670-   SPLEN20177400-   SPLEN20180980//METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10)    (METHIONINE-TRNA LIGASE) (METRS).//3.40E-57//133aa//87%//P56192-   SPLEN20181570//TRICHOHYALIN.//7.80E-45//832aa//23%//P37709-   SPLEN20182850-   SPLEN20182990//Mus musculus actin-binding protein (ENC-1) mRNA,    complete cds.//1.90E-49//586aa//26%//U65079-   SPLEN20183020//BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE    PROTEOGLYCAN CORE PROTEIN PRECURSOR(HSPG) (PERLECAN)    (PLC).//1.20E-24//128aa//46%//Q05793-   SPLEN20183950-   SPLEN20187490//RESTIN (CYTOPLASMIC LINKER PROTEIN-170 ALPHA-2)    (CLIP-170) (REED-STERNBERG INTERMEDIATE FILAMENT ASSOCIATED    PROTEIN).//5.10E-09//411aa//22%//P30622-   SPLEN20190080-   SPLEN20190430//NEURALIZED PROTEIN.//2.80E-09//181aa//27%//P29503-   SPLEN20190770-   SPLEN20191020//Homo sapiens MIST mRNA, partial    cds.//1.50E-207//376aa//99%//AB032369-   SPLEN20192570-   SPLEN20193230-   SPLEN20193490-   SPLEN20193750-   SPLEN20193790//INTERFERON-REGULATED RESISTANCE GTP-BINDING PROTEIN    MXA (INTERFERON-INDUCED PROTEIN P78)    (IFI-78K).//0//572aa//98%//P20591-   SPLEN20195710//KINESIN LIGHT CHAIN    (KLC).//5.80E-28//145aa//45%//P46824-   SPLEN20197090-   SPLEN20197740-   SPLEN20197930//Rattus norvegicus putative transcription factor LUZP    (Luzp) mRNA, complete cds.//6.10E-124//275aa//90%//AF181259-   SPLEN20198390//TIPD PROTEIN.//2.80E-52//307aa//37%//015736-   SPLEN20199850-   SPLEN20200070-   SPLEN20200340-   SPLEN20201830//BONE/CARTILAGE PROTEOGLYCAN I PRECURSOR (BIGLYCAN)    (PG-S1).//2.50E-152//283aa//100%//P21810-   SPLEN20203590-   SPLEN20204670-   SPLEN20205120-   TESOP10000350-   TESOP10001600-   TESTI10000190//MUCIN 1 PRECURSOR (POLYMORPHIC EPITHELIAL MUCIN)    (PEM) (PEMT) (EPISIALIN) (TUMOR-ASSOCIATED MUCIN)    (CARCINOMA-ASSOCIATED MUCIN) (TUMOR-ASSOCIATED EPITHELIAL MEMBRANE    ANTIGEN) (EMA) (H23AG) (PEANUT-REACTIVE URINARY MUCIN) (PUM) (BREAST    CARCINOMA-ASSOCIATED ANTIGEN DF3).//1.40E-23//667aa//28%//P15941-   TESTI10000850-   TESTI10001570//ZINC FINGER PROTEIN 84 (ZINC FINGER PROTEIN    HPF2).//1.30E-148//598aa//46%//P51523-   TESTI20004310//TRICHOHYALIN.//1.40E-07//247aa//25%//P22793-   TESTI20005980-   TESTI20006160//CALCIUM-BINDING    PROTEIN.//1.10E-11//260aa//28%//P35085-   TESTI20006830//GAR2 PROTEIN.//2.90E-05//221aa//19%//P41891-   TESTI20012080//TUBULIN-TYROSINE LIGASE (EC 6.3.2.25)    (TTL).//2.20E-22//217aa//35%//P38584-   TESTI20012360-   TESTI20016970-   TESTI20019590-   TESTI20028020-   TESTI20029100//FIBROSIN (FRAGMENT).//1.60E-10//70aa//48%//Q60791-   TESTI20030200//DOUBLE-STRANDED RNA-SPECIFIC EDITASE 1 (EC 3.5.-.-)    (DSRNA ADENOSINE DEAMINASE) (RNA EDITING ENZYME    1).//1.90E-30//192aa//38%//P51400-   TESTI20030440//TRICHOHYALIN.//2.80E-21//412aa//26%//P37709-   TESTI20030610-   TESTI20031310//ALPHA-1-ANTICHYMOTRYPSIN PRECURSOR    (ACT).//7.80E-222//423aa//99%//P01011-   TESTI20031410//SYNAPTONEMAL COMPLEX PROTEIN 1 (SCP-1    PROTEIN).//6.10E-11//449aa//24%//Q03410-   TESTI20032770//ANTER-SPECIFIC PROLINE-RICH PROTEIN APG    PRECURSOR.//1.40E-07//121aa//37%//P40602-   TESTI20034750-   TESTI20035330-   TESTI20035790//SPLICING FACTOR, ARGININE/SERINE-RICH 4 (PRE-mRNA    SPLICING FACTOR SRP75).//2.30E-44//346aa//37%//Q08170-   TESTI20038240//Mus musculus neprilysin-like metallopeptidase 1 (Nl1)    mRNA, complete cds.//0//770aa//77%//AF176569-   TESTI20040850-   TESTI20041630//Mus musculus mRNA for type II cytokeratin, complete    cds.//1.30E-151//407aa//75%//AB033744-   TESTI20043130-   TESTI20043180//mouse mRNA for megakaryocyte potentiating factor,    complete cds.//8.40E-06//392aa//24%//D86370-   TESTI20043220//ORM1 PROTEIN.//6.40E-21//138aa//37%//P53224-   TESTI20043910-   TESTI20043990//APOMUCIN (MUCIN CORE PROTEIN)    (FRAGMENT).//8.70E-64//283aa//53%//P12021-   TESTI20044900//Strongylocentrotus purpuratus radial spokehead mRNA,    complete cds.//2.50E-150//447aa//61%//U73123-   TESTI20045390//Homo sapiens adlican mRNA, complete    cds.//1.80E-173//632aa//47%//AF245505-   TESTI20045740-   TESTI20046110-   TESTI20046490//Homo sapiens B2 gene partial cDNA, clone    B2E.//4.30E-33//284aa//34%//AJ002220-   TESTI20046540-   TESTI20046870//RETINAL-BINDING PROTEIN    (RALBP).//4.00E-06//244aa//23%//P49193-   TESTI20046890//Mus musculus axotrophin mRNA, complete    cds.//2.30E-40//173aa//53%//AF155739-   TESTI20047370//ATROPHIN-1 (DENTATORUBRAL-PALLIDOLUYSIAN ATROPHY    PROTEIN).//1.90E-22//695aa//28%//P54258-   TESTI20047930//Homo sapiens NY-REN-2 antigen mRNA, complete    cds.//1.50E-191//530aa//67%//AF155095-   TESTI20049060//H. sapiens mRNA for    SIRP-beta1.//2.50E-31//172aa//45%//Y10376-   TESTI20049410-   TESTI20049990-   TESTI20050170-   TESTI20050400-   TESTI20050720//SUCCINYL-COA:3-KETOACID-COENZYME A TRANSFERASE    PRECURSOR (EC 2.8.3.5) (SUCCINYL COA:3-OXOACID COA-TRANSFERASE)    (OXCT).//1.40E-208//519aa//74%//P55809-   TESTI20051200//POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE (EC    2.4.1.41) (PROTEIN-UDP ACETYLGALACTOSAMINYLTRANSFERASE)    (UDP-GALNAC:POLYPEPTIDE, N-ACETYLGALACTOSAMINYLTRANSFERASE)    (GALNAC-T1).//6.10E-50//189aa//49%//Q10472-   TESTI20051730//MALTOSE PERMEASE.//2.20E-05//327aa//23%//Q45632-   TESTI20052670-   TESTI20053070//HYPOTHETICAL WD-REPEAT PROTEIN    SLL0163.//5.00E-06//172aa//28%//Q55563-   TESTI20053260-   TESTI20053780-   TESTI20053800-   TESTI20053950-   TESTI20054700//Streptococcus pneumoniae strain g375 surface protein    PspC (pspC) gene, pspC-8.1 allele, complete    cds.//6.70E-11//219aa//32%//AF154015-   TESTI20055680//TRANSLATION INITIATION FACTOR    IF-2.//5.90E-08//98aa//41%//060841-   TESTI20055880-   TESTI20056030//Homo sapiens 88-kDa Golgi protein (GM88) mRNA,    complete cds.//3.60E-103//316aa//68%//AF204231-   TESTI20057200-   TESTI20057430//ZINC FINGER PROTEIN 8 (ZINC FINGER PROTEIN HF.18)    (FRAGMENT).//3.00E-307//543aa//99%//P17098-   TESTI20057590//TYROSINE-PROTEIN KINASE-LIKE 7 PRECURSOR(COLON    CARCINOMA KINASE-4) (CCK-4).//7.80E-07//152aa//27%//Q13308-   TESTI20057840//INHIBITOR OF APOPTOSIS PROTEIN (IAP) (INHIBITOR OF T    CELL APOPTOSIS PROTEIN).//7.20E-08//86aa//36%//Q90660-   TESTI20057880//CALDESMON (CDM).//6.20E-08//203aa//29%//P12957-   TESTI20058350//SERINE/THREONINE PROTEIN PHOSPHATASE 2A, 55 KDA    REGULATORY SUBUNIT B, GAMMA ISOFORM (PP2A, SUBUNIT B, B-GAMMA    ISOFORM) (PP2A, SUBUNIT B, B55-GAMMA ISOFORM) (PP2A, SUBUNIT B,    PR55-GAMMA ISOFORM) (PP2A, SUBUNIT B, R2-GAMMA    ISOFORM).//2.00E-232//426aa//99%//P50410-   TESTI20058920//TUBULIN ALPHA-3/ALPHA-7    CHAIN.//3.50E-148//277aa//98%//P05214-   TESTI20059080//Homo sapiens hyaluronidase (LUCA-3) mRNA, complete    cds.//2.40E-170//298aa//100%//AF040710-   TESTI20059330-   TESTI20059370-   TESTI20059480-   TESTI20059790-   TESTI20059810//ZINC FINGER PROTEIN 84 (ZINC FINGER PROTEIN    HPF2).//7.50E-153//536aa//52%//P51523-   TESTI20060080//MYOSIN HEAVY CHAIN, CLONE 203    (FRAGMENT).//5.30E-09//236aa//24%//P39922-   TESTI20060150-   TESTI20060350-   TESTI20060450-   TESTI20060830//Mus musculus mRNA for MIWI (piwi), complete    cds.//0//824aa//94%//AB032604-   TESTI20061090-   TESTI20061200//NITRITE EXTRUSION PROTEIN (NITRITE    FACILITATOR).//4.90E-05//379aa//23%//P46907-   TESTI20062120//poly(A)-specific ribonuclease (deadenylation    nuclease); deadenylation nuclease [Homo    sapiens]//1.00E-38//144aa//36%//NP_(—)002573-   TESTI20062180-   TESTI20062580-   TESTI20063330-   TESTI20063410-   TESTI20063600-   TESTI20064370-   TEST120064530//microtubule-associated protein like echinoderm EMAP    [Homo sapiens].//1.00E-173//562aa//48%//XP_(—)009139-   TESTI20064650//Rattus norvegicus myr 6 myosin heavy chain mRNA,    complete cds.//0//645aa//91%//U60416-   TESTI20064990-   TESTI20065650//INNER CENTROMERE PROTEIN    (INCENP).//1.00E-14//273aa//27%//P53352-   TESTI20066150-   TESTI20066170-   TESTI20066280-   TESTI20066330//FIBRONECTIN PRECURSOR.//9.10E-12//408aa//22%//Q91740-   TESTI20066590-   TESTI20066650//CELL DIVISION CONTROL PROTEIN    25.//2.20E-18//216aa//32%//P04821-   TESTI20067350-   TESTI20067440//INTRACELLULAR PROTEIN TRANSPORT PROTEIN    US01.//2.90E-11//553aa//20%//P25386-   TESTI20067480//ZINC FINGER PROTEIN 184 (FRAGMENT).//8.60E-134//421    aa//50%//Q99676-   TESTI20068530-   TESTI20068790//TRANS-ACTING TRANSCRIPTIONAL PROTEIN ICP0 (P135    PROTEIN) (IER 2.9/ER2.6).//7.50E-06//240aa//28%//P29128-   TESTI20068940-   TESTI20070400//Homo sapiens CTL2    gene.//5.90E-229//694aa//55%//AJ245621-   TEST120070740-   TESTI20071130//MYOSIN HEAVY CHAIN, CARDIAC MUSCLE ALPHA    ISOFORM.//6.30E-09//399aa//23%//Q02566-   TESTI20071630//GLIOMA PATHOGENESIS-RELATED PROTEIN (RTVP-1    PROTEIN).//5.10E-44//203aa//42%//P48060-   TESTI20073460-   TESTI20075240//HYPOTHETICAL ZINC FINGER PROTEIN    KIAA0961.//3.20E-145//492aa//56%//Q9Y2G7-   TESTI20076570//Homo sapiens mitogen-activated protein kinase    phosphatase x (MKPX) mRNA, complete    cds.//7.20E-66//126aa//100%//AF165519-   TESTI20076920-   TESTI20079060-   TESTI20079220//ZINC FINGER PROTEIN 29    (ZFP-29).//2.00E-73//281aa//49%//Q07230-   TESTI20079980//SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-1    (DISHEVELLED-1) (DSH HOMOLOG 1).//7.10E-212//413aa//93%//P51141-   TESTI20080460-   TESTI20081890//SPA-1 like protein p1294 [Rattus    norvegicus]//5.80E-129//385aa//41%//AF026504-   TESTI20083890-   TESTI20084250//OXYSTEROL-BINDING    PROTEIN.//3.70E-183//551aa//62%//P16258-   TESTI20085670-   TESTI20086840//CARTILAGE MATRIX PROTEIN PRECURSOR    (MATRILIN-1).//3.40E-09//181aa//29%//P05099-   TESTI20088840//ZINC-FINGER PROTEIN RFP (RET FINGER    PROTEIN).//2.60E-73//258aa//31%//Q62158-   TESTI20089290-   TESTI20090180-   TESTI20090970-   TESTI20091360-   TESTI20092170-   TESTI20093900-   TESTI20094620-   TESTI20095200//HYPOTHETICAL 98.3 KDA PROTEIN B0495.7 IN CHROMOSOME    II.//1.30E-63//328aa//40%//Q09216-   TESTI20095440//probable membrane protein YOR240w—yeast    (Saccharomyces cerevisiae)//1.00E-25//98aa//55%//S67133-   TESTI20095770//NEDD1 PROTEIN    (FRAGMENT).//5.80E-297//648aa//85%//P33215-   TESTI20095880//HYPOTHETICAL SYMPORTER    SLL1374.//3.80E-26//243aa//27%//P74168-   TESTI20097270-   TESTI20099350//MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B (CELLULAR MYOSIN    HEAVY CHAIN, TYPE B) (NMMHC-B).//1.50E-26//566aa//23%//P35580-   TESTI20100090//Homo sapiens endocytic receptor Endo180 (ENDO180)    mRNA, complete cds.//5.00E-161//317aa//93%//AF134838-   TESTI20102390-   TESTI20103690//Columba livia mRNA for    5′-nucleotidase.//2.70E-114//324aa//66%//AJ131243-   TESTI20104090//TRANSCRIPTIONAL ENHANCER FACTOR TEF-4 (EMBRYONIC TEA    DOMAIN-CONTAINING FACTOR) (ETF) (ETEF-1)    (TEAD-2).//1.60E-228//450aa//92%//P48301-   TESTI20105130//MYOTUBULARIN.//4.30E-95//537aa//38%//Q13496-   TESTI20105910//AMILORIDE-SENSITIVE SODIUM CHANNEL DELTA-SUBUNIT    (EPITHELIAL NA+ CHANNEL DELTA SUBUNIT) (DELTA ENAC)    (NONVOLTAGE-GATED SODIUM CHANNEL 1 DELTA SUBUNIT) (SCNED) (DELTA    NACH).//0//636aa//97%//P51172-   TESTI20106170//Mus musculus spermatid WD-repeat protein mRNA,    complete cds.//2.20E-167//367aa//83%//AF274321-   TESTI20106820//PROTEIN KINASE C, ETA TYPE (EC 2.7.1.-) (NPKC-ETA)    (PKC-L).//5.40E-53//97aa//100%//P24723-   TESTI20107240//EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 10    (EIF-3 THETA) (EUKARYOTIC TRANSLATION INITIATION FACTOR 3 LARGE    SUBUNIT) (PNLA-35).//5.60E-07//428aa//22%//Q40554-   TESTI20107320//G1/S-SPECIFIC CYCLIN    C-TYPE.//1.20E-05//130aa//26%//P93411-   TESTI20107340-   TESTI20108060//SERINE/THREONINE PROTEIN PHOSPHATASE PP1-BETA    CATALYTIC SUBUNIT (EC 3.1.3.16)    (PP-1B).//1.10E-78//145aa//100%//P37140-   TESTI20112540//CALDESMON (CDM).//9.10E-06//203aa//30%//P12957-   TESTI20112860//MYOSIN LIGHT CHAIN KINASE (EC 2.7.1.117)    (MLCK).//1.60E-54//290aa//40%//P25323-   TESTI20113150-   TESTI20113940-   TESTI20114480//Human 1(3)mbt protein homolog mRNA, complete    cds.//7.10E-146//582aa//49%//U89358-   TESTI20116050-   TESTI20116120//Aegilops squarrosa partial GAG56D gene for    gamma-gliadin, accession CIae 24.//3.10E-07//93aa//40%//AJ389681-   TESTI20117500-   TESTI20118460-   TESTI20120500-   TESTI20120900-   TESTI20121040//PROBABLE PROTEIN PHOSPHATASE 2C T23F11.1 (EC    3.1.3.16) (PP2C).//8.60E-13//91aa//39%//P49596-   TESTI20121710//HYPOTHETICAL 57.5 KDA PROTEIN IN VMA7-RPS25A    INTERGENIC REGION.//5.00E-08//292aa//26%//P53214-   TESTI20122070//Xenopus laevis ER1 mRNA, complete    cds.//1.80E-78//341aa//49%//AF015454-   TESTI20122440-   TESTI20124440-   TESTI20125280//M-PROTEIN, STRIATED    MUSCLE.//3.60E-68//295aa//46%//Q02173-   TESTI20125440-   TESTI20125920//G PROTEIN PATHWAY SUPPRESSOR 1 (GPS1 PROTEIN) (MFH    PROTEIN).//5.20E-199//367aa//98%//Q13098-   TESTI20126280//Mus musculus STAP mRNA for sperm tail associated    protein, complete cds.//4.60E-213//769aa//57%//AB029919-   TESTI20130530//INSULIN-DEGRADING ENZYME (EC 3.4.24.56) (INSULYSIN)    (INSULINASE) (INSULIN PROTEASE).//1.60E-237//464aa//94%//P14735-   TESTI20131440//CARBOXYPEPTIDASE A1 PRECURSOR (EC    3.4.17.1).//2.80E-107//332aa//58%//P15085-   TESTI20132310-   TESTI20132680-   TESTI20134010-   TESTI20134270-   TESTI20134680//CENTROMERIC PROTEIN E (CENP-E    PROTEIN).//2.40E-08//796aa//19%//Q02224-   TESTI20134970//M. musculus Tenr mRNA for RNA binding    protein.//5.50E-265//559aa//88%//X84693-   TESTI20136010//MYOSIN HEAVY CHAIN, NONMUSCLE (CELLULAR MYOSIN HEAVY    CHAIN) (NMMHC).//1.10E-11//438aa//23%//P14105-   TESTI20140970//V_segment translation product [Homo    sapiens].//6.30E-51//101aa//99%//AAC80210-   TEST120142480-   TESTI20142540//MPV17 PROTEIN.//8.00E-62//116aa//98%//P39210-   TESTI20143180//CENTROMERIC PROTEIN E (CENP-E    PROTEIN).//3.30E-09//507aa//22%//Q02224-   TESTI20144390//TESTIS-SPECIFIC PROTEIN    PBS13.//6.40E-76//251aa//63%//Q01755-   TESTI20145780//Mus musculus mRNA for SH2-containing leukocyte    protein 65.//1.20E-13//91aa//36%//Y17159-   TESTI20148380//TRANSFORMATION-SENSITIVE PROTEIN IEF SSP    3521.//2.50E-05//193aa//22%//P31948-   TESTI20149880-   TESTI20150420//RHO-GTPASE-ACTIVATING PROTEIN 1 (GTPASE-ACTIVATING    PROTEIN RHOGAP) (RHO-RELATED SMALL GTPASE PROTEIN ACTIVATOR) (CDC42    GTPASE-ACTIVATING PROTEIN)    (P50-RHOGAP).//4.50E-09//129aa//34%//Q07960-   TESTI20150920//PROTEIN PHOSPHATASES PP1 REGULATORY SUBUNIT    SDS22.//2.60E-16//193aa//34%//P22194-   TESTI20151050-   TESTI20151800-   TESTI20152490-   TEST120153310//LAMIN B3.//6.30E-13//104aa//41%//P48680-   TESTI20154370//HYALURONAN MEDIATED MOTILITY RECEPTOR (INTRACELLULAR    HYALURONIC ACID BINDING PROTEIN) (RECEPTOR FOR HYALURONAN-MEDIATED    MOTILITY).//1.10E-07//300aa//21%//075330-   TESTI20159380-   TESTI20161010-   TESTI20162780//COTE1 PROTEIN.//1.00E-107//207aa//99%//P81408-   TESTI20162980//DNA-DAMAGE INDUCIBLE PROTEIN    DDI1.//1.80E-39//174aa//48%//P40087-   TESTI20164210//PROTEIN KINASE C-BINDING PROTEIN NELL1 (NEL-LIKE    PROTEIN 1) (FRAGMENT).//1.60E-88//163aa//92%//Q92832-   TESTI20165680-   TESTI20165990-   TESTI20166290//Homo sapiens NY-REN-50 antigen mRNA, partial    cds.//3.00E-223//426aa//93%//AF155112-   TESTI20166670//HOMEOBOX PROTEIN HOX-B1    (HOX-2I).//6.70E-06//224aa//29%//P14653-   TESTI20167580-   TESTI20168880//BREAKPOINT CLUSTER REGION PROTEIN (EC    2.7.1.-).//2.10E-23//57aa//92%//P11274-   TESTI20169500//HYPOTHETICAL 51.9 KDA PROTEIN C27F1.04C IN CHROMOSOME    I.//9.50E-17//428aa//25%//Q10173-   TESTI20170170//Homo sapiens mRNA for chondroitin-4-sulfotransferase    (C4ST gene).//1.10E-53//277aa//40%//AJ269537-   TESTI20170280-   TESTI20170690-   TESTI20170890-   TESTI20171070//CYCLIC-AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-4    (DNA-BINDING PROTEIN TAXREB67) (CYCLIC AMP RESPONSE ELEMENT-BINDING    PROTEIN 2) (CREB2).//2.60E-63//136aa//91%//P18848-   TESTI20173050-   TESTI20173110-   TESTI20173960//ZINC FINGER PROTEIN 91 (ZINC FINGER PROTEIN HTF10)    (HPF7).//1.90E-104//335aa//48%//Q05481-   TESTI20175370//MYOSIN HEAVY CHAIN, NONMUSCLE (CELLULAR MYOSIN HEAVY    CHAIN) (NMMHC).//1.00E-11//290aa//25%//P14105-   TESTI20176450//thioredoxin interacting factor [Mus    musculus].//1.00E-75//300aa//46%//AAG32665-   TESTI20179230-   TESTI20179510-   TESTI20180600//Homo sapiens HOM-TES-85 tumor antigen mRNA, complete    cds.//8.10E-106//202aa//99%//AF124430-   TESTI20182210-   TESTI20182760//AMILORIDE-SENSITIVE SODIUM CHANNEL DELTA-SUBUNIT    (EPITHELIAL NA+ CHANNEL DELTA SUBUNIT) (DELTA ENAC)    (NONVOLTAGE-GATED SODIUM CHANNEL 1 DELTA SUBUNIT) (SCNED) (DELTA    NACH).//5.90E-185//336aa//99%//P51172-   TESTI20183680//EARLY NODULIN 20 PRECURSOR    (N-20).//5.10E-08//127aa//37%//P93329-   TESTI20184280-   TESTI20184750//LAMININ ALPHA-1 CHAIN PRECURSOR (LAMININ A    CHAIN).//2.30E-200//377aa//99%//P25391-   TESTI20184760//ZINC FINGER PROTEIN 29    (ZFP-29).//9.70E-74//281aa//49%//Q07230-   TESTI20184820-   TESTI20186110-   TESTI20192570-   TESTI20193080//GAR22 PROTEIN.//5.10E-153//313aa//92%//Q99501-   TESTI20193520-   TESTI20194880//PERIOD CIRCADIAN PROTEIN 1 (CIRCADIAN PACEMAKER    PROTEIN RIGUI) (HPER).//1.50E-11//288aa//30%//05534-   TESTI20196690//Bos taurus pyruvate dehydrogenase phosphatase    regulatory subunit precursor, mRNA, complete    cds.//9.10E-114//224aa//92%//AF026954-   TESTI20196970//THIMET OLIGOPEPTIDASE (EC 3.4.24.15) (ENDOPEPTIDASE    24.15) (MP78).//4.00E-106//147aa//100%//P52888-   TESTI20197030-   TESTI20197290-   TESTI20197600//TRANSCRIPTIONAL REPRESSOR    CTCF.//5.30E-120//271aa//82%//P49711-   TESTI20198540-   TESTI20198600-   TESTI20199110//disintegrin-like testicular metalloproteinase (EC    3.4.24.-) IVb—crab-eating macaque    (fragment)//1.00E-167//331aa//84%//165253-   TESTI20199980-   TESTI20200120-   TESTI20200840-   TESTI20201760//SYNAPTONEMAL COMPLEX PROTEIN 1 (SCP-1    PROTEIN).//4.70E-09//189aa//25%//Q15431-   TESTI20202830-   TESTI20204260-   TESTI20205100//TRICHOHYALIN.//2.60E-15//343aa//24%//P37709-   TESTI20205150-   TESTI20205250//phosphatidylinositol-4-phosphate 5-kinase homolog    T3K9.2—Arabidopsis thaliana//4.20E-21//194aa//33%//T02098-   TESTI20207170//Human testis-specific protein (TSPY) mRNA, complete    cds.//6.60E-111//231aa//96%//U58096-   TESTI20209050//HYPOTHETICAL 113.1 KDA PROTEIN IN PRE5-FET4    INTERGENIC REGION.//1.90E-05//462aa//22%//Q04893-   TESTI20210030-   TESTI20210570//RETINAL-BINDING PROTEIN    (RALBP).//5.00E-53//327aa//36%//P49193-   TESTI20211380-   TESTI20212970//PUTATIVE ATP-DEPENDENT RNA HELICASE    YIR002C.//5.90E-85//458aa//32%//P40562-   TESTI20214630-   TESTI20215310//Homo sapiens calcyclin binding protein mRNA, complete    cds.//6.60E-95//182aa//100%//AF057356-   TESTI20219110//TYROSINE-PROTEIN KINASE-LIKE 7 PRECURSOR(COLON    CARCINOMA KINASE-4) (CCK-4).//4.00E-23//53aa//100%//Q13308-   TESTI20219390-   TESTI20220230//Bos taurus Reissner's fiber glycoprotein I mRNA,    partial cds.//1.20E-10//77aa//50%//AF078930-   TESTI20221790-   TESTI20222030//Homo sapiens very long-chain acyl-CoA synthetase    (BG1) mRNA, complete cds.//6.10E-172//643aa//50%//AF179481-   TESTI20222460//DYNEIN GAMMA CHAIN, FLAGELLAR OUTER    ARM.//1.50E-138//589aa//46%//Q39575-   TESTI20223380-   TESTI20226520//TUBULIN-TYROSINE LIGASE (EC 6.3.2.25)    (TTL).//6.70E-06//164aa//30%//P38160-   TEST120227380//DEAD BOX PROTEIN 4 (VASA HOMOLOG)    (RVLG).//1.10E-263//577aa//86%//Q64060-   TESTI20228120//RHO-GTPASE-ACTIVATING PROTEIN 6 (RHO-TYPE    GTPASE-ACTIVATING PROTEIN RHOGAPX-1)    (FRAGMENT).//4.50E-12//164aa//34%//054834-   TESTI20228740//ZINC FINGER PROTEIN    135.//3.50E-25//132aa//43%//P52742-   TESTI20244220//MYOSIN HEAVY CHAIN IB (MYOSIN HEAVY CHAIN    IL).//6.50E-11//77aa//42%//P19706-   TESTI20244430//ANKYRIN 1 (ERYTHROCYTE ANKYRIN) (ANKYRIN R) (ANKYRINS    2.1 AND 2.2).//3.70E-15//173aa//35%//P16157-   TESTI20244460//ADENYLATE KINASE, CHLOROPLAST (EC 2.7.4.3) (ATP-AMP    TRANSPHOSPHORYLASE).//3.60E-34//209aa//37%//P43188-   TESTI20244730//Mus musculus alpha/beta hydrolase-1 mRNA, complete    cds.//8.20E-113//266aa//81%//AF189764-   TESTI20245600//HYPOTHETICAL 118.4 KDA PROTEIN IN BAT2-DAL5    INTERGENIC REGION PRECURSOR.//4.50E-05//236aa//27%//P47179-   TESTI20245860-   TESTI20246410-   TESTI20246480//Homo sapiens germline specific RNA binding protein    (DAZL1) mRNA, complete cds.//5.00E-22//86aa//55%//U66726-   TESTI20247440//Human BLu protein testis isoform (BLu) mRNA, complete    cds.//5.40E-45//91aa//96%//U70880-   TESTI20248850-   TESTI20249360//Homo sapiens DEME-6 mRNA, partial    cds.//4.70E-94//299aa//56%//AF007170-   TESTI20250220//TRICHOHYALIN.//5.40E-54//537aa//30%//P37709-   TESTI20250630//Columba livia mRNA for    5′-nucleotidase.//3.80E-115//328aa//66%//AJ131243-   TESTI20251440//Rattus norvegicus (rsec6) mRNA, complete    cds.//3.80E-31//379aa//28%//U32575-   TESTI20251610//INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H2    PRECURSOR (ITI HEAVY CHAIN H2).//1.10E-07//182aa//26%//002668-   TESTI20251740//FYN-BINDING PROTEIN (SLP-76 ASSOCIATED PROTEIN)    (SLAP-130).//6.30E-16//88aa//50%//015117-   TESTI20252690//SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-3    (DISHEVELLED-3) (DSH HOMOLOG 3)    (KIAA0208).//4.60E-137//304aa//85%//Q92997-   TESTI20254030//Homo sapiens actin-binding double-zinc-finger protein    (abLIM) mRNA, complete cds.//6.70E-150//280aa//96%//AF005654-   TESTI20254090-   TESTI20254480-   TESTI20254990//ZINC FINGER PROTEIN GLI3 (NEURAL SPECIFIC DNA BINDING    PROTEIN XGLI3) (XGLI-3).//6.50E-46//105aa//75%//Q91660-   TESTI20255460//Mus musculus mRNA for MIWI (piwi), complete    cds.//1.50E-225//864aa//49%//AB032604-   TESTI20256560//NUF1 PROTEIN (SPINDLE POLY BODY SPACER PROTEIN    SPC110).//5.70E-05//590aa//19%//P32380-   TESTI20257910//HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN G    PRECURSOR (HLA G ANTIGEN).//1.90E-122//223aa//100%//P17693-   TESTI20258720//ANKYRIN 1 (ERYTHROCYTE ANKYRIN) (ANKYRIN R) (ANKYRINS    2.1 AND 2.2).//1.20E-10//233aa//27%//P16157-   TEST120259110-   TESTI20259200-   TESTI20260140-   TESTI20260640//helicase II homolog—fruit fly (Drosophila    sp.)//2.70E-27//374aa//27%//T13889-   TESTI20261040//DPY-19 PROTEIN.//2.10E-47//316aa//34%//P34413-   TESTI20261160//Mus musculus rasGAP-activating-like protein mRNA,    complete cds.//1.60E-21//129aa//41%//AF086714-   TESTI20261680//HEAT SHOCK PROTEIN 30C.//1.70E-08//136aa//27%//P30218-   TESTI20262150//Rattus norvegicus mRNA for voltage-gated ca channel,    complete cds.//0//822aa//87%//AB018253-   TESTI20262940//TUBULIN-TYROSINE LIGASE (EC 6.3.2.25)    (TTL).//5.70E-10//218aa//25%//P38160-   TESTI20264530//PUTATIVE SERINE/THREONINE-PROTEIN KINASE PKWA (EC    2.7.1.-).//5.60E-18//219aa//34%//P49695-   TESTI20264910-   TEST120265150-   TESTI20265340-   TESTI20265890-   TESTI20266050//52 KDA RO PROTEIN (SJOGREN SYNDROME TYPE A ANTIGEN    (SS-A)) (RO(SS-A)).//2.10E-77//472aa//38%//P19474-   TESTI20268240//Homo sapiens membrane-associated nucleic acid binding    protein mRNA, partial cds.//1.90E-52//412aa//36%//AF255303-   TESTI20269250-   TESTI20269360-   TESTI20270130//FIBRILLARIN.//2.10E-11//97aa//43%//Q22053-   TESTI20271790//Human p76 mRNA, complete    cds.//6.9e-317//496aa//99%//U81006-   TESTI20272380-   TESTI20274960//ZINC FINGER PROTEIN 83 (ZINC FINGER PROTEIN    HPF1).//7.90E-126//342aa//63%//P51522-   TESTI20277300-   TESTI20278280//Mus musculus p53 apoptosis-associated target (Perp)    mRNA, complete cds.//3.40E-84//155aa//88%//AF249870-   TESTI20282420//Mus musculus EPCS26 mRNA, complete    cds.//2.40E-19//122aa//33%//AF250838-   TESTI20282530//ZINC FINGER PROTEIN    135.//1.60E-56//271aa//39%//P52742-   TESTI20282900-   TESTI20284260//HISTONE H₂B F (H₂B    291A).//2.10E-22//120aa//43%//P10853-   TESTI20285230//DOUBLE-STRANDED RNA-SPECIFIC EDITASE 1 (EC 3.5.-.-)    (DSRNA ADENOSINE DEAMINASE) (RNA EDITING ENZYME    1).//2.10E-20//192aa//38%//P51400-   TESTI20286590//Human type 3 inositol 1,4,5-trisphosphate receptor    (ITPR3) mRNA, complete cds.//1.00E-93//185aa//100%//U01062-   TESTI20287760-   THYMU10004280//ZINC-FINGER PROTEIN HT2A (72 KDA TAT-INTERACTING    PROTEIN).//7.90E-13//87aa//42%//Q13049-   THYMU20006020//ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA,    MITOCHONDRIAL PRECURSOR (EC 1.1.1.41) (ISOCITRIC DEHYDROGENASE)    (NAD+-SPECIFIC ICDH).//2.60E-120//229aa//99%//P50213-   THYMU20007020-   THYMU20007750-   THYMU20008000-   THYMU20009460-   THYMU20009500-   THYMU20009710-   THYMU20010180//MOB1 PROTEIN (MPS1 BINDER    1).//2.60E-31//136aa//50%//P40484-   THYMU20010710-   THYMU20012020-   THYMU20012560-   THYMU20013250//LIM DOMAIN KINASE 2 (EC 2.7.1.-)    (LIMK-2).//3.50E-213//354aa//99%//P53671-   THYMU20013810//Human SEC7 homolog Tic (TIC) mRNA, complete    cds.//2.30E-88//138aa//96%//U63127-   THYMU20014430-   THYMU20017270-   THYMU20018250-   THYMU20018390-   THYMU20019000-   THYMU20019260//ZINC FINGER PROTEIN 85 (ZINC FINGER PROTEIN HPF4)    (HTF1).//6.80E-49//137aa//68%//Q03923-   THYMU20020370-   THYMU20020800//LMBR1 long form [Mus    musculus].//3.00E-69//198aa//55%//AAF91092-   THYMU20021090//Homo sapiens Sex comb on midleg homolog 1 isoform 1    (SCMH1) mRNA, complete cds.//4.40E-80//149aa//63%//AF149045-   THYMU20021540-   THYMU20023560//DNA BINDING PROTEIN    RFX2.//6.70E-25//59aa//94%//P48378-   THYMU20024500//NEUROFILAMENT TRIPLET M PROTEIN (160 KDA    NEUROFILAMENT PROTEIN) (NF-M).//6.20E-06//296aa//22%//P16053-   THYMU20025480-   THYMU20026950//Mus musculus ROSA 26 transcription AS ROSA26AS mRNA,    complete cds.//2.20E-12//285aa//23%//U83176-   THYMU20028150//AXONIN-1 PRECURSOR (AXONAL GLYCOPROTEIN TAG-1)    (TRANSIENT AXONAL GLYCOPROTEIN 1).//2.20E-33//301aa//31%//Q02246-   THYMU20028410//Mus musculus Pax transcription activation domain    interacting protein PTIP mRNA, complete    cds.//1.70E-144//345aa//81%//AF104261-   THYMU20029830-   THYMU20030460//Homo sapiens tumor endothelial marker 7 precursor    (TEM7) mRNA, complete cds.//2.10E-123//230aa//99%//AF279144-   THYMU20030690-   THYMU20031330//Homo sapiens putative nucleotide binding protein    mRNA, complete cds.//1.00E-18//64aa//82%//AF118394-   THYMU20032820//ZINC FINGER PROTEIN    135.//1.40E-82//258aa//55%//P52742-   THYMU20034400//26S proteasome subunit p44.5 [Homo    sapiens]//8.80E-29//71aa//91%//AB003102-   THYMU20034790-   THYMU20036500-   THYMU20039320//PUTATIVE SERINE/THREONINE-PROTEIN KINASE PKWA (EC    2.7.1.-).//1.40E-09//206aa//27%//P49695-   THYMU20043440-   THYMU20043560-   THYMU20044100-   THYMU20044520-   THYMU20046350-   THYMU20046770-   THYMU20049060//SPLICING FACTOR, ARGININE/SERINE-RICH 2 (SPLICING    FACTOR SC35) (SC-35) (SPLICING COMPONENT, 35 KDA) (PR264    PROTEIN).//6.00E-41//119aa//76%//P30352-   THYMU20050010-   THYMU20051340-   THYMU20052460//PHORBOLIN I    (FRAGMENTS).//5.80E-20//111aa//45%//P31941-   THYMU20052830//Homo sapiens mRNA for immunoglobulin lambda heavy    chain.//1.50E-237//477aa//90%//Y14737-   THYMU20054800-   THYMU20055450-   THYMU20055460//ESTERASE D (EC    3.1.1.1).//7.60E-57//107aa//100%//P10768-   THYMU20055740-   THYMU20055760//Mus musculus group IIF secreted phospholipase A2    (Pla2g2f) mRNA, complete cds.//1.70E-73//165aa//75%//AF166099-   THYMU20058550-   THYMU20060480-   THYMU20062520-   THYMU20062610//DYNEIN GAMMA CHAIN, FLAGELLAR OUTER    ARM.//1.70E-156//585aa//50%//Q39575-   THYMU20062770//UROMODULIN PRECURSOR (TAMM-HORSFALL URINARY    GLYCOPROTEIN) (THP).//4.20E-22//253aa//28%//P27590-   THYMU20063650//Homo sapiens mRNA for putative    ribulose-5-phosphate-epimerase, partial    cds.//9.30E-57//116aa//97%//AJ224326-   THYMU20064680-   THYMU20066660//Homo sapiens putative ATP-dependent RNA helicase ROK1    mRNA, complete cds.//9.20E-153//361aa//85%//AF077033-   THYMU20069130-   THYMU20069460-   THYMU20069650-   THYMU20070250//TRANSKETOLASE (EC 2.2.1.1)    (TK).//4.50E-288//513aa//96%//P29401-   THYMU20071120//ZINC FINGER PROTEIN 85 (ZINC FINGER PROTEIN HPF4)    (HTF1).//1.40E-229//536aa//74%//Q03923-   THYMU20071460-   THYMU20072580-   THYMU20073070-   THYMU20073080-   THYMU20077250//T-CELL-SPECIFIC TRANSCRIPTION FACTOR 1 (TCF-1)    (T-CELL FACTOR 1) (TRANSCRIPTION    FACTOR-7).//4.10E-90//176aa//96%//Q00417-   THYMU20078020-   THYMU20078240-   THYMU20079690-   THYMU20080490-   THYMU20081110//PINCH PROTEIN (PARTICULARY INTERESTING NEW CYS-HIS    PROTEIN).//4.00E-28//60aa//86%//P48059-   THYMU20083390-   THYMU20083500-   THYMU20083830//Homo sapiens angiostatin binding protein 1 mRNA,    complete cds.//2.30E-09//230aa//28%//AF286598-   THYMU20084520-   THYMU20086430-   THYMU20087270//POTENTIAL PHOSPHOLIPID-TRANSPORTING ATPASE IIB (EC    3.6.1.-).//7.20E-154//235aa//88%//P98195-   THYMU20089170-   THYMU20089900-   THYMU20090230//Homo sapiens ribonucleoprotein mRNA, complete    cds.//9.30E-73//133aa//100%//L32610-   THYMU20091040-   THYMU20095920//Homo sapiens nuclear prelamin A recognition factor    mRNA, complete cds.//2.90E-94//178aa//100%//AF128406-   THYMU20096580//SERYL-TRNA SYNTHETASE (EC 6.1.1.11) (SERINE-TRNA    LIGASE) (SERRS).//9.90E-20//45aa//97%//P49591-   THYMU20097920//mitogen inducible gene    mig-2—human//2.50E-197//477aa//55%//S69890-   THYMU20098350//KERATIN, TYPE II CYTOSKELETAL 5 (CYTOKERATIN 5) (K5)    (CK 5) (58 KDA CYTOKERATIN).//3.40E-267//577aa//89%//P13647-   THYMU20099060//IG ALPHA-1 CHAIN C    REGION.//1.70E-196//353aa//99%//P01876-   THYMU20100940//POTENTIAL PHOSPHOLIPID-TRANSPORTING ATPASE IR (EC    3.6.1.-) (FRAGMENT).//0//646aa//99%//Q9Y2G3-   THYMU20104480//TRICHOHYALIN.//2.90E-21//300aa//28%//P37709-   THYMU20106990//Mus musculus evectin-2 (Evt2) mRNA, complete    cds.//2.20E-112//222aa//90%//AF189817-   THYMU20110720//PROBABLE AMINOTRANSFERASE T01B11.2 (EC    2.6.1.-).//6.90E-40//211aa//41%//P91408-   THYMU20112570-   THYMU20112590//Homo sapiens AP-4 adaptor complex beta4 subunit mRNA,    complete cds.//3.40E-306//534aa//99%//AF092094-   THYMU20115380-   THYMU20115730-   THYMU20117850-   THYMU20120240//Arabidopsis thaliana ubiquitin-specific protease    (AtUBP4) mRNA, complete cds.//4.10E-18//179aa//28%//U76846-   THYMU20120730//ALDEHYDE DEHYDROGENASE, DIMERIC NADP-PREFERRING (EC    1.2.1.5) (ALDH CLASS 3).//2.10E-203//379aa//99%//P30838-   THYMU20121040//ELONGATION FACTOR 1-DELTA    (EF-1-DELTA).//5.30E-149//281 aa//99%//P29692-   THYMU20128910-   THYMU20129020-   THYMU20130470-   THYMU20134260-   THYMU20137050-   THYMU20137570-   THYMU20139160-   THYMU20140510-   THYMU20143230//Homo sapiens mRNA for stabilin-1 (stab1    gene).//1.70E-177//317aa//99%//AJ275213-   THYMU20145990//nesca protein [Homo    sapiens].//1.90E-152//282aa//98%//NP_(—)055143-   THYMU20148010-   THYMU20149230-   THYMU20150190-   THYMU20151610//Homo sapiens antigen NY-CO-1 (NY-CO-1) mRNA, complete    cds.//1.40E-181//344aa//100%//AF039687-   THYMU20153210//Homo sapiens Diff33 protein homolog mRNA, complete    cds.//4.00E-120//404aa//54%//AF164794-   THYMU20154790-   THYMU20157620-   THYMU20163600-   THYMU20170080//Homo sapiens SIT    protein.//9.50E-48//78aa//98%//AJ010059-   THYMU20170230//Homo sapiens sarcosine dehydrogenase (SARDH) mRNA,    complete cds.//1.80E-183//260aa//99%//AF095735-   THYMU20171580-   THYMU20174490-   THYMU20174790-   THYMU20175260-   THYMU20176010//VEGETATIBLE INCOMPATIBILITY PROTEIN    HET-E-1.//1.80E-20//256aa//28%//Q00808-   THYMU20177070-   THYMU20178440//Homo sapiens mRNA for immunoglobulin lambda heavy    chain.//2.20E-229//479aa//88%//Y14737-   THYMU20181890-   THYMU20184550-   THYMU20185470-   THYMU20185650//DIAPHANOUS PROTEIN HOMOLOG    1.//1.30E-20//85aa//44%//060610-   THYMU20187210-   THYMU20191970//Homo sapiens FLAMINGO 1 mRNA, partial    cds.//1.80E-54//450aa//36%//AF234887-   TKIDN10000620//Homo sapiens Tax interaction protein 2 mRNA, partial    cds.//1.20E-56//114aa//100%//AF028824-   TKIDN10001710-   TKIDN10001920//ZINC FINGER PROTEIN 85 (ZINC FINGER PROTEIN HPF4)    (HTF1).//3.20E-97//226aa//73%//Q03923-   TRACH20011010//GLUCOAMYLASE S1/S2 PRECURSOR (EC 3.2.1.3) (GLUCAN    1,4-ALPHA-GLUCOSIDASE) (1,4-ALPHA-D-GLUCAN    GLUCOHYDROLASE).//4.30E-17//593aa//22%//P08640-   TRACH20011540//TUMOR-ASSOCIATED ANTIGEN    L6.//4.70E-57//113aa//97%//P30408-   TRACH20012490-   TRACH20021000-   TRACH20021380//ADENYLATE CYCLASE, TYPE V (EC 4.6.1.1) (ATP    PYROPHOSPHATE-LYASE) (CA(2+)-INHIBITABLE ADENYLYL    CYCLASE).//1.20E-276//492aa//95%//P30803-   TRACH20025370-   TRACH20026640-   TRACH20029880-   TRACH20040390//MATERNAL PUMILIO    PROTEIN.//1.20E-177//812aa//47%//P25822-   TRACH20041090-   TRACH20043360//PUTATIVE KINESIN-LIKE PROTEIN    C2F12.13.//2.30E-55//333aa//39%//014343-   TRACH20044990-   TRACH20049500-   TRACH20051590-   TRACH20057200-   TRACH20058000-   TRACH20073990-   TRACH20080810-   TRACH20081270-   TRACH20090060//SYNAPTOTAGMIN IV.//1.10E-12//301aa//25%//P40749-   TRACH20091070//ALDEHYDE DEHYDROGENASE, DIMERIC NADP-PREFERRING (EC    1.2.1.5) (ALDH CLASS 3).//1.00E-173//328aa//98%//P30838-   TRACH20093400//TRICHOHYALIN.//2.30E-13//701aa//20%//P37709-   TRACH20093480-   TRACH20098510//MYOSIN HEAVY CHAIN, GIZZARD SMOOTH    MUSCLE.//1.10E-20//640aa//21%//P10587-   TRACH20101590-   TRACH20104510-   TRACH20108240//ribonucleoprotein—African clawed    frog//4.10E-118//223aa//96%//S40774-   TRACH20113020//SELENIDE, WATER DIKINASE 2 (EC 2.7.9.3)    (SELENOPHOSPHATE SYNTHETASE 2) (SELENIUM DONOR PROTEIN    2).//1.80E-207//364aa//96%//Q99611-   TRACH20122980//HYPOTHETICAL PROTEIN    MJ0798.//6.80E-13//211aa//22%//Q58208-   TRACH20123870-   TRACH20124970-   TRACH20125620-   TRACH20129180-   TRACH20131230//Homo sapiens oxysterol binding protein-related    protein 3 (ORP3) mRNA, complete    cds.//7.50E-282//608aa//62%//AY008372-   TRACH20139280-   TRACH20140180-   TRACH20143710//RAB GERANYLGERANYLTRANSFERASE ALPHA SUBUNIT (EC    2.5.1.-) (RAB GERANYL-GERANYLTRANSFERASE ALPHA SUBUNIT) (RAB GG    TRANSFERASE) (RAB GGTASE).//9.70E-07//142aa//33%//Q92696-   TRACH20149500//KERATIN, TYPE I CUTICULAR HA6 (HAIR KERATIN, TYPE I    HA6).//1.10E-62//215aa//60%//076013-   TRACH20149720-   TRACH20149740//EXCITATORY AMINO ACID TRANSPORTER 5 (RETINAL    GLUTAMATE TRANSPORTER).//5.00E-76//152aa//98%//000341-   TRACH20158240-   TRACH20159390-   TRACH20160800-   TRACH20163470//Mus musculus putative thymic stromal co-transporter    TSCOT mRNA, complete cds.//3.20E-41//187aa//34%//AF148145-   TRACH20164100//RETROVIRUS-RELATED PROTEASE (EC    3.4.23.-).//1.40E-32//113aa//56%//P10265-   TRACH20164810-   TRACH20165330-   TRACH20165540//Human alpha-1 type I collagen gene surrounding    osteogenesis imperfecta OI type II    deletion.//4.00E-05//102aa//37%//M11162-   TRACH20167090-   TRACH20170860//IG DELTA CHAIN C    REGION.//1.60E-212//383aa//100%//P01880-   TRACH20173680//Homo sapiens mRNA for LAK-4p, complete    cds.//3.50E-80//410aa//38%//AB002405-   TRACH20174980-   TRACH20182780-   TRACH20185120-   TRACH20188350//Homo sapiens mRNA for centaurin    beta2.//3.80E-60//204aa//56%//AJ238248-   TRACH20190460//MONO- AND DIACYLGLYCEROL LIPASE PRECURSOR (EC    3.1.1.-) (MDGL).//2.60E-11//195aa//28%//P25234-   UMVEN10001380-   UTERU10001060//ETS-DOMAIN PROTEIN    ELK-1.//1.40E-39//88aa//93%//P19419-   UTERU10001870-   UTERU20000230-   UTERU20000950//Homo sapiens PC326 protein (PC326) mRNA, complete    cds.//2.80E-55//112aa//100%//AF150734-   UTERU20011760-   UTERU20013890-   UTERU20016580//POTENTIAL TRANSCRIPTIONAL    ADAPTOR.//1.90E-37//323aa//31%//Q02336-   UTERU20026620//ZINC FINGER PROTEIN 75.//7.50E-82//174aa//82%//P51815-   UTERU20027360-   UTERU20029930-   UTERU20031350-   UTERU20035770-   UTERU20040150-   UTERU20040370-   UTERU20040390-   UTERU20040730-   UTERU20041630//ZINC FINGER PROTEIN 184    (FRAGMENT).//3.30E-75//239aa//44%//Q99676-   UTERU20041970-   UTERU20045200-   UTERU20051790//guanylate kinase-interacting protein 1 Maguin-1,    membrane-associated—rat//8.20E-26//267aa//33%//T18293-   UTERU20064120//MYELOID UPREGULATED    PROTEIN.//1.30E-79//245aa//66%//035682-   UTERU20065470-   UTERU20079240-   UTERU20083020-   UTERU20086530//GLYCODELIN PRECURSOR (GD) (PREGNANCY-ASSOCIATED    ENDOMETRIAL ALPHA-2 GLOBULIN) (PEG) (PAEG) (PLACENTAL PROTEIN 14)    (PROGESTERONE-ASSOCIATED ENDOMETRIAL PROTEIN)    (PROGESTAGEN-ASSOCIATED ENDOMETRIAL    PROTEIN).//6.00E-73//140aa//99%//P09466-   UTERU20087070//COMPLEMENT C1R COMPONENT PRECURSOR (EC    3.4.21.41).//4.80E-206//360aa//99%//P00736-   UTERU20087850//Homo sapiens mRNA for mucolipidin (ML4    gene).//2.70E-34//184aa//42%//AJ293970-   UTERU20089300-   UTERU20089390//Plectonema boryanum kinesin light chain (KLC) gene,    complete cds.//3.30E-38//216aa//43%//U78597-   UTERU20089620//Homo sapiens radical fringe (RFNG) gene, partial    cds.//1.50E-31//65aa//100%//AF108139-   UTERU20090940-   UTERU20091470-   UTERU20094830//SINGLE-MINDED HOMOLOG 2 (SIM TRANSCRIPTION FACTOR)    (MSIM).//8.70E-09//427aa//25%//Q61079-   UTERU20095100-   UTERU20099040//ZINC TRANSPORTER 2    (ZNT-2).//9.80E-96//242aa//76%//Q62941-   UTERU20099510//ZINC FINGER PROTEIN    135.//2.20E-107//346aa//54%//P52742-   UTERU20101150//NUCLEAR FACTOR NF-KAPPA-B P49    SUBUNIT.//2.20E-07//76aa//47%//Q04860-   UTERU20102260-   UTERU20103040-   UTERU20103200-   UTERU20104310//DNA-DIRECTED RNA POLYMERASE II 14.4 KDA POLYPEPTIDE    (EC 2.7.7.6) (RPB6) (RPB14.4).//1.80E-48//97aa//100%//P41584-   UTERU20106510-   UTERU20121140-   UTERU20122520//MOESIN (MEMBRANE-ORGANIZING EXTENSION SPIKE    PROTEIN).//6.00E-37//399aa//28%//P26042-   UTERU20125810-   UTERU20127030//LAMININ BETA-2 CHAIN    PRECURSOR(S-LAMININ).//6.80E-175//377aa//92%//P55268-   UTERU20127150-   UTERU20128560//26.4 KDA PROTEIN IN RUVC-ASPS INTERGENIC    REGION.//2.60E-17//120aa//34%//P24237-   UTERU20132620//AXONEME-ASSOCIATED PROTEIN MST101    (2).//1.40E-15//231aa//31%//Q08696-   UTERU20134830//pellino (Drosophila) homolog 2 [Homo    sapiens]//1.40E-153//361aa//72%//NP_(—)067078-   UTERU20139760//solute carrier family 25 (mitochondrial carrier;    peroxisomal membrane protein, 34 kD), member 17 [Homo    sapiens]//5.40E-100//203aa//97%//XP_(—)001136-   UTERU20140010-   UTERU20167570-   UTERU20168960//Homo sapiens actin filament associated protein (AFAP)    mRNA, complete cds.//2.60E-68//364aa//43%//AF188700-   UTERU20169020//HOMEOBOX PROSPERO-LIKE PROTEIN PROX1 (PROX    1).//1.30E-54//117aa//74%//Q91018-   UTERU20173030-   UTERU20176230-   UTERU20177150//Homo sapiens zinc finger protein dp mRNA, complete    cds.//4.60E-10//104aa//40%//AF153201-   UTERU20181270-   UTERU20185220//Human mRNA for transcriptional activator hSNF2a,    complete cds.//1.60E-125//246aa//98%//D26155-   UTERU20188670//HFM1 PROTEIN.//5.10E-19//234aa//26%//P51979-   UTERU20188840

1. (canceled)
 2. A polypeptide encoded by a polynucleotide selected fromthe group consisting of the following (a) to (g): (a) a polynucleotidecomprising a protein-coding region of the nucleotide sequence of any oneof SEQ ID NOs: 1 to 1970: (b) a polynucleotide encoding a polypeptidecomprising the amino acid sequence of any one of SEQ ID NOs: 1971 to3940: (c) a polynucleotide comprising a nucleotide sequence encoding apolypeptide comprising the amino acid sequence of any one of SEQ ID NOs:1971 to 3940, wherein in said amino acid sequence, one or more aminoacids have been substituted, deleted, inserted and/or added, and whereinsaid nucleotide sequence encodes a polypeptide functionally equivalentto a polypeptide comprising the selected amino acid sequence; (d) apolynucleotide hybridizing to a polynucleotide comprising the nucleotidesequence of any one of SEQ ID NOs: 1 to 1970, wherein said nucleotidesequence encodes a polypeptide functionally equivalent to a polypeptideencoded by the selected nucleotide sequence; (e) a polynucleotidecomprising a nucleotide sequence encoding a partial amino acid sequenceof a polypeptide encoded by the polynucleotide according to any one of(a) to (d); (f) a polynucleotide comprising a nucleotide sequence havingat least 70% identity to the nucleotide sequence of any one of SEQ IDNOs: 1 to 1970; and (g) a polynucleotide comprising a nucleotidesequence having at least 90% identity to the nucleotide sequence of anyone of SEQ ID NOs: 1 to 1970, or a partial peptide thereof. 3-7.(canceled)
 8. A method for producing the polypeptide or the partialpeptide of claim 2, said method comprising the steps of culturing atransformant carrying a polynucleotide selected from the groupconsisting of the following (a) to (g): (a) a polynucleotide comprisinga protein-coding region of the nucleotide sequence of any one of SEQ IDNOs: 1 to 1970; (b) a polynucleotide encoding a polypeptide comprisingthe amino acid sequence of any one of SEQ ID NOs: 1971 to 3940; (c) apolynucleotide comprising a nucleotide sequence encoding a polypeptidecomprising the amino acid sequence of any one of SEQ ID NOs: 1971 to3940, wherein, in said amino acid sequence, one or more amino acids havebeen substituted, deleted, inserted and/or added, and wherein saidnucleotide sequence encodes a polypeptide functionally equivalent to apolypeptide comprising the selected amino acid sequence; (d) apolynucleotide hybridizing to a polynucleotide comprising the nucleotidesequence of any one of SEQ ID NOs: 1 to 1970, wherein said nucleotidesequence encodes a polypeptide functionally equivalent to a polypeptideencoded by the selected nucleotide sequence; (e) a polynucleotidecomprising a nucleotide sequence encoding a partial amino acid sequenceof a polypeptide encoded by the polynucleotide according to any one of(a) to (d); (f) a polynucleotide comprising a nucleotide sequence havingat least 70% identity to the nucleotide sequence of any one of SEQ IDNOs: 1 to 1970; and (g) a polynucleotide comprising a nucleotidesequence having at least 90% identity to the nucleotide sequence of anyone of SEQ ID NOs: 1 to 1970, and recovering an expression product.9-14. (canceled)